| Definition | Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome. |
|---|---|
| Accession | NC_009972 |
| Length | 6,346,587 |
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The map label for this gene is lgrB [H]
Identifier: 159898382
GI number: 159898382
Start: 2170286
End: 2174872
Strand: Direct
Name: lgrB [H]
Synonym: Haur_1858
Alternate gene names: 159898382
Gene position: 2170286-2174872 (Clockwise)
Preceding gene: 159898381
Following gene: 159898383
Centisome position: 34.2
GC content: 53.26
Gene sequence:
>4587_bases ATGACTATGAATGAGCGCGAAGTGTTTGCCTTCCCGATGTCGTTTGCCCAGCAACGGCTCTGGTTTTTGGAGCAACTTCA GCCGAATAGTGCCTTGTATCATATCGCTAGTTTGCTGGAAATTCAGGGGTCGCTTGATCTGGCGGCGTTGCAGCAGAGCA TTAACCAGATTGTTGTGCGTCACGAGACGTTGCGTACCACCTTTGGCATGGTCGATCAAACGCCGATGCAATTGATCAGC AGTGAGTTGACGCTCACCCCGGTTGTCCATAATTTGCAGGCGCTTGAGCCTGAGCAACGCTGGTTTGTGGCGCTTGAACA GGCCAAAGCCAGTTGTTTGGTGCCATTTGATTTGAGCCAAGGCCCGTTGGTGCGGCTTGAGTTGTTTCAACTTGGGCCTG AGCATTGCTTGATGACGGTCGTGCTGCACCACATTATTGCTGATGGCTGGTCGATGGAACTTTTCATTCAGGAACTAGTC AGCAGCTATGAGGCCTATCGCGCGGGTTTTCATCCGCAACTTGCGCCCTTGGCCTTGCAATATGCCGATTATAGCGAGTG GCAGCGTGAATGGCTGGCTAGCCCACGCCAGCAGCAACAATTGGATTTTTGGCAACAGCAATTGGCCGATGCCCCCAAGC GTTTGGAGTTAGCAACTGATCACCCTCGGCCTGCTCAGCAGAGTTTTGCGGGGAGCACGTTGAGTTTTGGCATCCCAAGC CAACAAACTAGTCAACTGCGCAGTTTGGCCCAGCAAACCCAAACTACGCCGTTTATGCTAGCTTTGGCGGTGTTTGCCAG CTTGTTGAGCCGTTATAGCCGCCAAGATCAGGTGTTGATTGGCTCGCCGATTGCCAACCGTACTACCGCCGAAGCCCAAC CGCTGATTGGCTTTTTCGTCAATACAGTGGTTTTCAAGGTACAACTGAGTCCAAACCTCGATTTGCTGAGCCTAGTTGAG CAGGTACGCGAGCAAAGTTTGGCGGTCTATGCCAACCAAGATGTGCCGTTTGAGCAGGTGGTGCAGCAGTTACAGCTTGA GCGCAATCTGAGCCATACGCCCATTTTTCAGGTGATGCTAGCTTACCAAAATGTGCCGAGCCAGCAACTGAGCATCGCCA ACTTGACAATCAAACAGCTGCCGCTGGATTTGGGTTATGCCAAATTTGACCTAACTTTATTTATTGAGGAAACTCCAGCA GGGCTAGTTGGGCGCTTGGAATATAACCGTGATTTGTTTGAGCCTGCCACGATTGCGCGCTTGCGCGACCATTTCTTGCG TTTGCTAGGCCACGCCTTGGCTCAGCCAACCCAACCACTGGCCCAAATCAGTATCTTGAGCGCTGCCGAATGCCAACAGC TTTTGGTCGATTGGAACCAAACGCAGCAGCCGTTCCCCGACCAACTTGGTTTGCAGCATTTGGTCGCGCAGCAAGTACAA CGTACTCCCAATGCTCCAGCGATGCGTTGGAATAACCAAATAATCTGCTATACAGAGCTTGAGCAACGTGCCAACCAATT AGCCCATTTGCTGCTGCAACGTGGCGTTACCCAAGGCTCAATCGTTGGAGTCTATGCGACGCGCTGCCCAGAAATGATCA TCAGCTTGCTGGCGATTTTGAAGGCTGGTGCTGCCTACTTGCCGCTTGATCCGGCCTATCCTGCTGAACGCTTGCACTAT TTGGTGGCCGATTCGGCGGCGAGTTTGATTGTGCAAGCCAGCCATCAGGCGCTGCCAACCCTCGTTAGTACAGCTGAAAC GCTTGATGTTGTAGCCGAAGCTGAAACGCTGGCTAGCTTGCCAACCACTGCTCCGATGGTTGATTTCGACCCGCAGCAAT TGGCCTATGTGATTTATACCTCTGGCTCGACTGGCAAGCCCAAAGGTGTGCTGATTCAGCATCAAGGGGTGGTGAATTAT CTGCACTGGGCGATTCATTATTATCCATTTGAGCAGGGTGCTGGTGCACCGCTGGCCTCGTCGTTGGCCTTCGATGCCAC AATTACGGCATTGTGGGGGCCACTCTGTACGGGCAAAACCATCGATTTGCTGCCTGAGCAGGATGAGCTAGAAGTCTTGG CGCAACGCCTGAGCAGCGAAGATTATAGCGTGCTCAAAATCACCCCAGCGCATATGGAAGCGCTTAGTCAGCTGGTTGCG CCCGACCAAATTGGCTCAAGCAAGGCCTTTGTGATTGGCGGCGAGGCCTTGTTGCAGCAACATGTGGCCTTTTGGCAAAC CAACGCTCCCAACCTGCGCTTGATCAATGAATATGGCCCAACCGAGACGGTAGTTGGCTGTGTGATCTATCAAGCCCAAG CTGCGCCAAGCGAATGGGCTGCCGTGCCGATTGGCCGCCCGATTGCCAATACCCAGTTGTATGTGCTTGATCCGGCAGGT TTGCCAGTGCCGATTGGCGTGCCTGGCGAGTTGTATATCGCTGGCTTGGGTGTTGGGCGCGGCTACCATGGGCGGCCTGA ATTGACCGCCGAGCGCTTTGTGCGGCTGGAACAATTGGCTGGGGTGCAGGCAGAACTTGCCCGTTGCCAACAGCCTCAGC CAGCGTTTGAACGCTTGTATCGTTCAGGCGATTTGGTGCGCTATCTGCCCGATGGTAATCTCGAATATCTTGGGCGGATC GATCAGCAAGTCAAACTCCATGGCTTTCGAATTGAGCTTGGCGAGATCGAAGCCACGCTGGCGAGCCATCCGACGGTGCA CGCGGCGGTGGCCATGATTCGCGAAGATCGGCCTGGACATAAGCGACTGGTTGCCTATGTGGTCGCTGAGCCAACTGCCA ATCAGGATACTTCGATTGTTTTGACCCATGTTGCCCAACAGTTGCCCCACTATATGCTGCCAAGCGTGGTGATTTGGCTC GATAGCTTGCCATTAACCCCCAATGGCAAAGTTGATCGTCAAGCGCTGCCCGCGCCTGAGATCAACCAAACTGCGCTTGA TTCGGCCCAAACCACCCCACTCGATCAGTATGAAGCTCAATTGATGGCTATTTGGCAGCGAGTGTTAGGACTGAAGGCCG TTGATCGCCATGCCAATTTCTTTAGCCTTGGTGGCGATTCGATTTTGGTGATGCAGGTAGTCGGCATTGCACGGCAGCAT GGCCTGATTCTAACCCCACGCTTGTTGTTCCAAAACCAAACGATTGCCAGCTTGGCCCAAGCGATTCGCCAGCAAACCCA AGCTAAGCCCGCGCTTGATCCCTTGAGTTTGCAGGGCATTGTGCCGCTTAGCCCAATGCAACATTGGCTATTTGAGCGCC AACTGGCCCAGCCCGCCCATGTCAACCAAAGTATTGTGCTCAAGTTACAAACGGGGTTAGCGACCGAACAAATACAGGCA GCGCTTGATCAATTAGTGCGTTTGCACCCAAGTTTGCGTTTGATCTTTACCCAAACTGCGGCTTGGCAACAACGCTATGA GCCAGCCGCCAGCGTGCCCTTGCGCGAATTACAGCAACCAACATTAAGCCAGCAACAAGTCTGTGATGCCGAATTGCAAG CTTCATTCGATTTAGCTCAAGTGCCGTTGTTACGAGCCTCGTTGTGGCGTGGTATCGACCACGATCAATTGCTGTTGGTG GCGCACCATAGCATTATCGACGGGGTTTCGTGGCGAATTGTGCTCGAAGATTTGGCTTTGTTGCTCAACCAACAAGCTGT GCCAGCGGCAACCACGCCATTTAGTGAGTGGGCCGAATATCAGGTGCAGCAAGCCCAAACCCCGCAATTGCTGAGCCAAC TCGCCTATTGGCGCTCGACGATTGAAGCCATCACGCCGATTCCTCAGCTAGCTCAAGCGGGGTTGGTTGGCGAAGCACAG CGCTTTCAAACCAAGCTTAATCCTGAATTGACCGAGCAACTGCTGCATCACGCACCTGAGCGCAGCCGTACCAGCGTGGC CGAGTTGCTGATCACTGGCTTGGCGATAGCTTTCCAGCGTTGGTCAAATCTACAACAATTAGTGCTTGATATTGAAAGCC ATGGTCGCGAATCGCTTGACCCTGAGCATGATTTCAGCCGGAGTTTGGGCTGGTTCACCAGTTTGTACCCAGTGCGCTTG GATTTCCCCACTACCAATGAGCCAAACCAGTGGATTAAGCAGATCAAAGAAAGCTTGCGGGCAGTGCCGCAAGCCGGAGC GGGCTATGGCATGTTGCGCTATTTGCACGCTGATCCAGCGATTCGCGCGAGCCTTGTGCCAACTCACGCCCCAGCAATTG CCTTCAACTACCTTGGTCAGCTCGATAACCAACAAACTTTAGCACCATTCCAAGGGCTAAATTTGGAGTTTGCCAGCCAA ACCTTGGCTCCCACCAACCAACGCAGTCATGCCTTAGAGCTTAATTGTTATAGCACTGATGGCTGTTTGGTGTTCGATTG GGAATGTCATCAGACAGCGCGGGCAGCCGTTGAACACTTGGCCGAGCAGTATCAAATAGCCTTAGCCGAGTTGTTGCAAG TACCAACCACAACTGCTAGCTTGGCTCCCTCGGATTTTCCAGCAGCTCGCGTCAAGGCCAACGATCTCGATCGATTGTTG GCTCGTTTGAAAGCAAAGGGGCAATAG
Upstream 100 bases:
>100_bases AGATTGCTAAACCAACCGCGCTCAAACGTCAGCGCCAACGGGTCAATTTGAATACGGCTGGCTTTGGCCAAATTGCTGAA AGCAACGACGGAGGTGCAGC
Downstream 100 bases:
>100_bases CGGTGGACAATATTCAGGATATTTATGAATTATCGCCAATGCAGCAGGGCATGCTGTTTCATACCATCGCTAGCCCGACT GCTGGAATGTACCTTGAACA
Product: amino acid adenylation domain-containing protein
Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]
Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]
Number of amino acids: Translated: 1528; Mature: 1527
Protein sequence:
>1528_residues MTMNEREVFAFPMSFAQQRLWFLEQLQPNSALYHIASLLEIQGSLDLAALQQSINQIVVRHETLRTTFGMVDQTPMQLIS SELTLTPVVHNLQALEPEQRWFVALEQAKASCLVPFDLSQGPLVRLELFQLGPEHCLMTVVLHHIIADGWSMELFIQELV SSYEAYRAGFHPQLAPLALQYADYSEWQREWLASPRQQQQLDFWQQQLADAPKRLELATDHPRPAQQSFAGSTLSFGIPS QQTSQLRSLAQQTQTTPFMLALAVFASLLSRYSRQDQVLIGSPIANRTTAEAQPLIGFFVNTVVFKVQLSPNLDLLSLVE QVREQSLAVYANQDVPFEQVVQQLQLERNLSHTPIFQVMLAYQNVPSQQLSIANLTIKQLPLDLGYAKFDLTLFIEETPA GLVGRLEYNRDLFEPATIARLRDHFLRLLGHALAQPTQPLAQISILSAAECQQLLVDWNQTQQPFPDQLGLQHLVAQQVQ RTPNAPAMRWNNQIICYTELEQRANQLAHLLLQRGVTQGSIVGVYATRCPEMIISLLAILKAGAAYLPLDPAYPAERLHY LVADSAASLIVQASHQALPTLVSTAETLDVVAEAETLASLPTTAPMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNY LHWAIHYYPFEQGAGAPLASSLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSVLKITPAHMEALSQLVA PDQIGSSKAFVIGGEALLQQHVAFWQTNAPNLRLINEYGPTETVVGCVIYQAQAAPSEWAAVPIGRPIANTQLYVLDPAG LPVPIGVPGELYIAGLGVGRGYHGRPELTAERFVRLEQLAGVQAELARCQQPQPAFERLYRSGDLVRYLPDGNLEYLGRI DQQVKLHGFRIELGEIEATLASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWL DSLPLTPNGKVDRQALPAPEINQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANFFSLGGDSILVMQVVGIARQH GLILTPRLLFQNQTIASLAQAIRQQTQAKPALDPLSLQGIVPLSPMQHWLFERQLAQPAHVNQSIVLKLQTGLATEQIQA ALDQLVRLHPSLRLIFTQTAAWQQRYEPAASVPLRELQQPTLSQQQVCDAELQASFDLAQVPLLRASLWRGIDHDQLLLV AHHSIIDGVSWRIVLEDLALLLNQQAVPAATTPFSEWAEYQVQQAQTPQLLSQLAYWRSTIEAITPIPQLAQAGLVGEAQ RFQTKLNPELTEQLLHHAPERSRTSVAELLITGLAIAFQRWSNLQQLVLDIESHGRESLDPEHDFSRSLGWFTSLYPVRL DFPTTNEPNQWIKQIKESLRAVPQAGAGYGMLRYLHADPAIRASLVPTHAPAIAFNYLGQLDNQQTLAPFQGLNLEFASQ TLAPTNQRSHALELNCYSTDGCLVFDWECHQTARAAVEHLAEQYQIALAELLQVPTTTASLAPSDFPAARVKANDLDRLL ARLKAKGQ
Sequences:
>Translated_1528_residues MTMNEREVFAFPMSFAQQRLWFLEQLQPNSALYHIASLLEIQGSLDLAALQQSINQIVVRHETLRTTFGMVDQTPMQLIS SELTLTPVVHNLQALEPEQRWFVALEQAKASCLVPFDLSQGPLVRLELFQLGPEHCLMTVVLHHIIADGWSMELFIQELV SSYEAYRAGFHPQLAPLALQYADYSEWQREWLASPRQQQQLDFWQQQLADAPKRLELATDHPRPAQQSFAGSTLSFGIPS QQTSQLRSLAQQTQTTPFMLALAVFASLLSRYSRQDQVLIGSPIANRTTAEAQPLIGFFVNTVVFKVQLSPNLDLLSLVE QVREQSLAVYANQDVPFEQVVQQLQLERNLSHTPIFQVMLAYQNVPSQQLSIANLTIKQLPLDLGYAKFDLTLFIEETPA GLVGRLEYNRDLFEPATIARLRDHFLRLLGHALAQPTQPLAQISILSAAECQQLLVDWNQTQQPFPDQLGLQHLVAQQVQ RTPNAPAMRWNNQIICYTELEQRANQLAHLLLQRGVTQGSIVGVYATRCPEMIISLLAILKAGAAYLPLDPAYPAERLHY LVADSAASLIVQASHQALPTLVSTAETLDVVAEAETLASLPTTAPMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNY LHWAIHYYPFEQGAGAPLASSLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSVLKITPAHMEALSQLVA PDQIGSSKAFVIGGEALLQQHVAFWQTNAPNLRLINEYGPTETVVGCVIYQAQAAPSEWAAVPIGRPIANTQLYVLDPAG LPVPIGVPGELYIAGLGVGRGYHGRPELTAERFVRLEQLAGVQAELARCQQPQPAFERLYRSGDLVRYLPDGNLEYLGRI DQQVKLHGFRIELGEIEATLASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWL DSLPLTPNGKVDRQALPAPEINQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANFFSLGGDSILVMQVVGIARQH GLILTPRLLFQNQTIASLAQAIRQQTQAKPALDPLSLQGIVPLSPMQHWLFERQLAQPAHVNQSIVLKLQTGLATEQIQA ALDQLVRLHPSLRLIFTQTAAWQQRYEPAASVPLRELQQPTLSQQQVCDAELQASFDLAQVPLLRASLWRGIDHDQLLLV AHHSIIDGVSWRIVLEDLALLLNQQAVPAATTPFSEWAEYQVQQAQTPQLLSQLAYWRSTIEAITPIPQLAQAGLVGEAQ RFQTKLNPELTEQLLHHAPERSRTSVAELLITGLAIAFQRWSNLQQLVLDIESHGRESLDPEHDFSRSLGWFTSLYPVRL DFPTTNEPNQWIKQIKESLRAVPQAGAGYGMLRYLHADPAIRASLVPTHAPAIAFNYLGQLDNQQTLAPFQGLNLEFASQ TLAPTNQRSHALELNCYSTDGCLVFDWECHQTARAAVEHLAEQYQIALAELLQVPTTTASLAPSDFPAARVKANDLDRLL ARLKAKGQ >Mature_1527_residues TMNEREVFAFPMSFAQQRLWFLEQLQPNSALYHIASLLEIQGSLDLAALQQSINQIVVRHETLRTTFGMVDQTPMQLISS ELTLTPVVHNLQALEPEQRWFVALEQAKASCLVPFDLSQGPLVRLELFQLGPEHCLMTVVLHHIIADGWSMELFIQELVS SYEAYRAGFHPQLAPLALQYADYSEWQREWLASPRQQQQLDFWQQQLADAPKRLELATDHPRPAQQSFAGSTLSFGIPSQ QTSQLRSLAQQTQTTPFMLALAVFASLLSRYSRQDQVLIGSPIANRTTAEAQPLIGFFVNTVVFKVQLSPNLDLLSLVEQ VREQSLAVYANQDVPFEQVVQQLQLERNLSHTPIFQVMLAYQNVPSQQLSIANLTIKQLPLDLGYAKFDLTLFIEETPAG LVGRLEYNRDLFEPATIARLRDHFLRLLGHALAQPTQPLAQISILSAAECQQLLVDWNQTQQPFPDQLGLQHLVAQQVQR TPNAPAMRWNNQIICYTELEQRANQLAHLLLQRGVTQGSIVGVYATRCPEMIISLLAILKAGAAYLPLDPAYPAERLHYL VADSAASLIVQASHQALPTLVSTAETLDVVAEAETLASLPTTAPMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNYL HWAIHYYPFEQGAGAPLASSLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSVLKITPAHMEALSQLVAP DQIGSSKAFVIGGEALLQQHVAFWQTNAPNLRLINEYGPTETVVGCVIYQAQAAPSEWAAVPIGRPIANTQLYVLDPAGL PVPIGVPGELYIAGLGVGRGYHGRPELTAERFVRLEQLAGVQAELARCQQPQPAFERLYRSGDLVRYLPDGNLEYLGRID QQVKLHGFRIELGEIEATLASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWLD SLPLTPNGKVDRQALPAPEINQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANFFSLGGDSILVMQVVGIARQHG LILTPRLLFQNQTIASLAQAIRQQTQAKPALDPLSLQGIVPLSPMQHWLFERQLAQPAHVNQSIVLKLQTGLATEQIQAA LDQLVRLHPSLRLIFTQTAAWQQRYEPAASVPLRELQQPTLSQQQVCDAELQASFDLAQVPLLRASLWRGIDHDQLLLVA HHSIIDGVSWRIVLEDLALLLNQQAVPAATTPFSEWAEYQVQQAQTPQLLSQLAYWRSTIEAITPIPQLAQAGLVGEAQR FQTKLNPELTEQLLHHAPERSRTSVAELLITGLAIAFQRWSNLQQLVLDIESHGRESLDPEHDFSRSLGWFTSLYPVRLD FPTTNEPNQWIKQIKESLRAVPQAGAGYGMLRYLHADPAIRASLVPTHAPAIAFNYLGQLDNQQTLAPFQGLNLEFASQT LAPTNQRSHALELNCYSTDGCLVFDWECHQTARAAVEHLAEQYQIALAELLQVPTTTASLAPSDFPAARVKANDLDRLLA RLKAKGQ
Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 4 acyl carrier domains [H]
Homologues:
Organism=Homo sapiens, GI187761345, Length=549, Percent_Identity=23.8615664845173, Blast_Score=84, Evalue=1e-15, Organism=Homo sapiens, GI187761343, Length=549, Percent_Identity=23.8615664845173, Blast_Score=84, Evalue=1e-15, Organism=Homo sapiens, GI115511026, Length=552, Percent_Identity=21.9202898550725, Blast_Score=77, Evalue=1e-13, Organism=Escherichia coli, GI1786801, Length=1080, Percent_Identity=29.3518518518519, Blast_Score=328, Evalue=1e-90, Organism=Escherichia coli, GI1790505, Length=536, Percent_Identity=24.2537313432836, Blast_Score=105, Evalue=2e-23, Organism=Escherichia coli, GI145693145, Length=558, Percent_Identity=22.4014336917563, Blast_Score=98, Evalue=4e-21, Organism=Escherichia coli, GI1788107, Length=560, Percent_Identity=23.2142857142857, Blast_Score=91, Evalue=6e-19, Organism=Escherichia coli, GI1786810, Length=508, Percent_Identity=25.7874015748031, Blast_Score=88, Evalue=5e-18, Organism=Escherichia coli, GI221142682, Length=511, Percent_Identity=22.8962818003914, Blast_Score=86, Evalue=2e-17, Organism=Escherichia coli, GI1789201, Length=372, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17550940, Length=1099, Percent_Identity=21.9290263876251, Blast_Score=176, Evalue=1e-43, Organism=Caenorhabditis elegans, GI17556356, Length=1180, Percent_Identity=21.9491525423729, Blast_Score=144, Evalue=3e-34, Organism=Caenorhabditis elegans, GI17531443, Length=509, Percent_Identity=19.6463654223969, Blast_Score=91, Evalue=5e-18, Organism=Caenorhabditis elegans, GI32563687, Length=539, Percent_Identity=20.5936920222635, Blast_Score=72, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6319591, Length=959, Percent_Identity=25.0260688216893, Blast_Score=264, Evalue=7e-71, Organism=Saccharomyces cerevisiae, GI6319699, Length=201, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24648676, Length=593, Percent_Identity=31.8718381112985, Blast_Score=217, Evalue=4e-56, Organism=Drosophila melanogaster, GI24581924, Length=549, Percent_Identity=23.8615664845173, Blast_Score=87, Evalue=7e-17, Organism=Drosophila melanogaster, GI21356947, Length=497, Percent_Identity=23.5412474849095, Blast_Score=77, Evalue=7e-14, Organism=Drosophila melanogaster, GI18859661, Length=497, Percent_Identity=23.5412474849095, Blast_Score=68, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR010071 - InterPro: IPR009081 - InterPro: IPR020845 - InterPro: IPR000873 - InterPro: IPR001242 - InterPro: IPR010060 - InterPro: IPR006163 - InterPro: IPR020806 - InterPro: IPR006162 [H]
Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]
EC number: 2.7.7.- [C]
Molecular weight: Translated: 169724; Mature: 169593
Theoretical pI: Translated: 5.53; Mature: 5.53
Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTMNEREVFAFPMSFAQQRLWFLEQLQPNSALYHIASLLEIQGSLDLAALQQSINQIVVR CCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH HETLRTTFGMVDQTPMQLISSELTLTPVVHNLQALEPEQRWFVALEQAKASCLVPFDLSQ HHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCC GPLVRLELFQLGPEHCLMTVVLHHIIADGWSMELFIQELVSSYEAYRAGFHPQLAPLALQ CCEEEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH YADYSEWQREWLASPRQQQQLDFWQQQLADAPKRLELATDHPRPAQQSFAGSTLSFGIPS HCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEECCCCCCCCHHHHHCCCCEECCCCC QQTSQLRSLAQQTQTTPFMLALAVFASLLSRYSRQDQVLIGSPIANRTTAEAQPLIGFFV HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHH NTVVFKVQLSPNLDLLSLVEQVREQSLAVYANQDVPFEQVVQQLQLERNLSHTPIFQVML HHHEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHH AYQNVPSQQLSIANLTIKQLPLDLGYAKFDLTLFIEETPAGLVGRLEYNRDLFEPATIAR HHHCCCHHHEEHHHEEHHHCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHH LRDHFLRLLGHALAQPTQPLAQISILSAAECQQLLVDWNQTQQPFPDQLGLQHLVAQQVQ HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH RTPNAPAMRWNNQIICYTELEQRANQLAHLLLQRGVTQGSIVGVYATRCPEMIISLLAIL HCCCCCCEEECCEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH KAGAAYLPLDPAYPAERLHYLVADSAASLIVQASHQALPTLVSTAETLDVVAEAETLASL HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PTTAPMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNYLHWAIHYYPFEQGAGAPLAS CCCCCCCCCCHHHEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHEEECCCCCCCCHHH SLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSVLKITPAHMEALSQLVA HHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHC PDQIGSSKAFVIGGEALLQQHVAFWQTNAPNLRLINEYGPTETVVGCVIYQAQAAPSEWA CCCCCCCCEEEECHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCC AVPIGRPIANTQLYVLDPAGLPVPIGVPGELYIAGLGVGRGYHGRPELTAERFVRLEQLA CCCCCCCCCCCEEEEECCCCCCEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHC GVQAELARCQQPQPAFERLYRSGDLVRYLPDGNLEYLGRIDQQVKLHGFRIELGEIEATL CHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHCCHHEEEEEEEEEHHHHHHHH ASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWL HCCCHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH DSLPLTPNGKVDRQALPAPEINQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANF HCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCE FSLGGDSILVMQVVGIARQHGLILTPRLLFQNQTIASLAQAIRQQTQAKPALDPLSLQGI EECCCCCCHHHHHHHHHHHCCEEECHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC VPLSPMQHWLFERQLAQPAHVNQSIVLKLQTGLATEQIQAALDQLVRLHPSLRLIFTQTA CCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEHHH AWQQRYEPAASVPLRELQQPTLSQQQVCDAELQASFDLAQVPLLRASLWRGIDHDQLLLV HHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEE AHHSIIDGVSWRIVLEDLALLLNQQAVPAATTPFSEWAEYQVQQAQTPQLLSQLAYWRST EHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH IEAITPIPQLAQAGLVGEAQRFQTKLNPELTEQLLHHAPERSRTSVAELLITGLAIAFQR HHHHCCCHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH WSNLQQLVLDIESHGRESLDPEHDFSRSLGWFTSLYPVRLDFPTTNEPNQWIKQIKESLR HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH AVPQAGAGYGMLRYLHADPAIRASLVPTHAPAIAFNYLGQLDNQQTLAPFQGLNLEFASQ HCCCCCCCHHHHHHHHCCCCHHEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH TLAPTNQRSHALELNCYSTDGCLVFDWECHQTARAAVEHLAEQYQIALAELLQVPTTTAS HCCCCCCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC LAPSDFPAARVKANDLDRLLARLKAKGQ CCCCCCCCHHCCHHHHHHHHHHHHCCCC >Mature Secondary Structure TMNEREVFAFPMSFAQQRLWFLEQLQPNSALYHIASLLEIQGSLDLAALQQSINQIVVR CCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH HETLRTTFGMVDQTPMQLISSELTLTPVVHNLQALEPEQRWFVALEQAKASCLVPFDLSQ HHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCC GPLVRLELFQLGPEHCLMTVVLHHIIADGWSMELFIQELVSSYEAYRAGFHPQLAPLALQ CCEEEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH YADYSEWQREWLASPRQQQQLDFWQQQLADAPKRLELATDHPRPAQQSFAGSTLSFGIPS HCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEECCCCCCCCHHHHHCCCCEECCCCC QQTSQLRSLAQQTQTTPFMLALAVFASLLSRYSRQDQVLIGSPIANRTTAEAQPLIGFFV HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHH NTVVFKVQLSPNLDLLSLVEQVREQSLAVYANQDVPFEQVVQQLQLERNLSHTPIFQVML HHHEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHH AYQNVPSQQLSIANLTIKQLPLDLGYAKFDLTLFIEETPAGLVGRLEYNRDLFEPATIAR HHHCCCHHHEEHHHEEHHHCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHH LRDHFLRLLGHALAQPTQPLAQISILSAAECQQLLVDWNQTQQPFPDQLGLQHLVAQQVQ HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH RTPNAPAMRWNNQIICYTELEQRANQLAHLLLQRGVTQGSIVGVYATRCPEMIISLLAIL HCCCCCCEEECCEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH KAGAAYLPLDPAYPAERLHYLVADSAASLIVQASHQALPTLVSTAETLDVVAEAETLASL HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PTTAPMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNYLHWAIHYYPFEQGAGAPLAS CCCCCCCCCCHHHEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHEEECCCCCCCCHHH SLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSVLKITPAHMEALSQLVA HHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHC PDQIGSSKAFVIGGEALLQQHVAFWQTNAPNLRLINEYGPTETVVGCVIYQAQAAPSEWA CCCCCCCCEEEECHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCC AVPIGRPIANTQLYVLDPAGLPVPIGVPGELYIAGLGVGRGYHGRPELTAERFVRLEQLA CCCCCCCCCCCEEEEECCCCCCEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHC GVQAELARCQQPQPAFERLYRSGDLVRYLPDGNLEYLGRIDQQVKLHGFRIELGEIEATL CHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHCCHHEEEEEEEEEHHHHHHHH ASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWL HCCCHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH DSLPLTPNGKVDRQALPAPEINQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANF HCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCE FSLGGDSILVMQVVGIARQHGLILTPRLLFQNQTIASLAQAIRQQTQAKPALDPLSLQGI EECCCCCCHHHHHHHHHHHCCEEECHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC VPLSPMQHWLFERQLAQPAHVNQSIVLKLQTGLATEQIQAALDQLVRLHPSLRLIFTQTA CCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEHHH AWQQRYEPAASVPLRELQQPTLSQQQVCDAELQASFDLAQVPLLRASLWRGIDHDQLLLV HHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEE AHHSIIDGVSWRIVLEDLALLLNQQAVPAATTPFSEWAEYQVQQAQTPQLLSQLAYWRST EHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH IEAITPIPQLAQAGLVGEAQRFQTKLNPELTEQLLHHAPERSRTSVAELLITGLAIAFQR HHHHCCCHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH WSNLQQLVLDIESHGRESLDPEHDFSRSLGWFTSLYPVRLDFPTTNEPNQWIKQIKESLR HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH AVPQAGAGYGMLRYLHADPAIRASLVPTHAPAIAFNYLGQLDNQQTLAPFQGLNLEFASQ HCCCCCCCHHHHHHHHCCCCHHEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH TLAPTNQRSHALELNCYSTDGCLVFDWECHQTARAAVEHLAEQYQIALAELLQVPTTTAS HCCCCCCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC LAPSDFPAARVKANDLDRLLARLKAKGQ CCCCCCCCHHCCHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: Phosphopantetheine. [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]
Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser
General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA