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The map label for this gene is etfA [H]

Identifier: 159898360

GI number: 159898360

Start: 2134702

End: 2135679

Strand: Direct

Name: etfA [H]

Synonym: Haur_1836

Alternate gene names: 159898360

Gene position: 2134702-2135679 (Clockwise)

Preceding gene: 159898359

Following gene: 159898361

Centisome position: 33.64

GC content: 51.84

Gene sequence:

>978_bases
ATGGCTAGTGGCGTTTGGGTCTTAATCGAACATAAAAATGGCGAAGTTGGGGCAATTTCCAAAGAATTATTGGGCAAAGG
CAAAGAAATTGCCGATGCACTTGGTCAAGCAGTAGCTGCCTTGGTGCTTGGTAACAATACCGCCAGCTTGGTCGAGCAAG
CATTTGCTGCTGGTGCAAGCAAAGCCTATGTGGTTGATGATGCCAATTTAGCGCAATATACCACTGATGGTTATGTCGCT
GCGGCCAAAGCTGCAATCGAAGCCCATCAACCAGAAGTCTTTTTGACTGGTTCATCGTTGCAAATGCGCGATTTTACGGG
AGCCTTGGCTGCTGAATTGGGTGTTGGGCTTGCTCCTGATGTGACCAACATTGGAGTTGAAGCTGGTCAATTGACCGCTG
TGCGCCCTTCACACGGCGCAAATGTGATCAACAGCCTAAGTTTTGGGGCTGCTCGCCCAGCGATTGCCTCGGTTCGTCGC
CAAGTTGGCAAGCCAATTGCTGGCGCTGGTGCTGGTGAAGTGGTCAATGTGGCGATGCCTGCGGTGAACATTCGCACCAA
AGTGCGTAACGTTGAGCAACGTACTGGCGCGGTTAACCTCGCCGATGCAACCGTGATCGTTTCGGGCGGTCGTGGGCTTG
GCTCACCTGAAAACTACGAAAAACTCATCCCTGAGTTGGCTCGGGTGATGGGCGGAACCCACGGTGCTTCTCGTGCGGTA
GTCGATGCTGGCTGGATCGCTTACGAGCGCCAAGTTGGCCAAACTGGCAAAACTGTTGCGCCAAAATTGTATGTTGCCTG
TGGTATTTCCGGCGCAATTCAGCACCTCGCTGGCATGCGCTCGTCAAATACCATCGTGGCGATCAACAAAGATCCTGAAG
CACCGATTTTCAAGGTGGCAACATATGGGATTGTTGGCGATATCAATGAAGTTTTGCCCGCTTTGACCGCTGAAGTCAAA
GCTAAAACTGGTCGCTAA

Upstream 100 bases:

>100_bases
GCCCATACCAATGGACTACTTGCGCTATATGATTGATGATCTTGACGTTGACTTTTGACTTTTGACTTTTGACTTTTGAC
TTTCACAATGAGGTGTTTTC

Downstream 100 bases:

>100_bases
ATAAATCTCATCGTACAGTGTAAGAACGCGGGTCAAAGCTTTGCTTTGATCCGCGTTTTGTTATGGTTAAACGCAATTAA
AATAGTTGCGCCGATAACAA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MASGVWVLIEHKNGEVGAISKELLGKGKEIADALGQAVAALVLGNNTASLVEQAFAAGASKAYVVDDANLAQYTTDGYVA
AAKAAIEAHQPEVFLTGSSLQMRDFTGALAAELGVGLAPDVTNIGVEAGQLTAVRPSHGANVINSLSFGAARPAIASVRR
QVGKPIAGAGAGEVVNVAMPAVNIRTKVRNVEQRTGAVNLADATVIVSGGRGLGSPENYEKLIPELARVMGGTHGASRAV
VDAGWIAYERQVGQTGKTVAPKLYVACGISGAIQHLAGMRSSNTIVAINKDPEAPIFKVATYGIVGDINEVLPALTAEVK
AKTGR

Sequences:

>Translated_325_residues
MASGVWVLIEHKNGEVGAISKELLGKGKEIADALGQAVAALVLGNNTASLVEQAFAAGASKAYVVDDANLAQYTTDGYVA
AAKAAIEAHQPEVFLTGSSLQMRDFTGALAAELGVGLAPDVTNIGVEAGQLTAVRPSHGANVINSLSFGAARPAIASVRR
QVGKPIAGAGAGEVVNVAMPAVNIRTKVRNVEQRTGAVNLADATVIVSGGRGLGSPENYEKLIPELARVMGGTHGASRAV
VDAGWIAYERQVGQTGKTVAPKLYVACGISGAIQHLAGMRSSNTIVAINKDPEAPIFKVATYGIVGDINEVLPALTAEVK
AKTGR
>Mature_324_residues
ASGVWVLIEHKNGEVGAISKELLGKGKEIADALGQAVAALVLGNNTASLVEQAFAAGASKAYVVDDANLAQYTTDGYVAA
AKAAIEAHQPEVFLTGSSLQMRDFTGALAAELGVGLAPDVTNIGVEAGQLTAVRPSHGANVINSLSFGAARPAIASVRRQ
VGKPIAGAGAGEVVNVAMPAVNIRTKVRNVEQRTGAVNLADATVIVSGGRGLGSPENYEKLIPELARVMGGTHGASRAVV
DAGWIAYERQVGQTGKTVAPKLYVACGISGAIQHLAGMRSSNTIVAINKDPEAPIFKVATYGIVGDINEVLPALTAEVKA
KTGR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=124, Percent_Identity=62.9032258064516, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI189181759, Length=124, Percent_Identity=62.9032258064516, Blast_Score=151, Evalue=7e-37,
Organism=Escherichia coli, GI1787990, Length=325, Percent_Identity=30.7692307692308, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786226, Length=222, Percent_Identity=39.1891891891892, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082157, Length=197, Percent_Identity=32.994923857868, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=292, Percent_Identity=39.3835616438356, Blast_Score=157, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6325261, Length=203, Percent_Identity=39.4088669950739, Blast_Score=145, Evalue=9e-36,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=38.0503144654088, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=38.0503144654088, Blast_Score=158, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33194; Mature: 33063

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGVWVLIEHKNGEVGAISKELLGKGKEIADALGQAVAALVLGNNTASLVEQAFAAGAS
CCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
KAYVVDDANLAQYTTDGYVAAAKAAIEAHQPEVFLTGSSLQMRDFTGALAAELGVGLAPD
CEEEEECCCHHEECCCCHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHCCCCCCC
VTNIGVEAGQLTAVRPSHGANVINSLSFGAARPAIASVRRQVGKPIAGAGAGEVVNVAMP
HHHCCCCCCEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECC
AVNIRTKVRNVEQRTGAVNLADATVIVSGGRGLGSPENYEKLIPELARVMGGTHGASRAV
CHHHHHHHHHHHHHCCEEEEECEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
VDAGWIAYERQVGQTGKTVAPKLYVACGISGAIQHLAGMRSSNTIVAINKDPEAPIFKVA
EEHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEE
TYGIVGDINEVLPALTAEVKAKTGR
HHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASGVWVLIEHKNGEVGAISKELLGKGKEIADALGQAVAALVLGNNTASLVEQAFAAGAS
CCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
KAYVVDDANLAQYTTDGYVAAAKAAIEAHQPEVFLTGSSLQMRDFTGALAAELGVGLAPD
CEEEEECCCHHEECCCCHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHCCCCCCC
VTNIGVEAGQLTAVRPSHGANVINSLSFGAARPAIASVRRQVGKPIAGAGAGEVVNVAMP
HHHCCCCCCEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECC
AVNIRTKVRNVEQRTGAVNLADATVIVSGGRGLGSPENYEKLIPELARVMGGTHGASRAV
CHHHHHHHHHHHHHCCEEEEECEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
VDAGWIAYERQVGQTGKTVAPKLYVACGISGAIQHLAGMRSSNTIVAINKDPEAPIFKVA
EEHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEE
TYGIVGDINEVLPALTAEVKAKTGR
HHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]