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The map label for this gene is yhdN [H]

Identifier: 159898321

GI number: 159898321

Start: 2085790

End: 2086776

Strand: Direct

Name: yhdN [H]

Synonym: Haur_1797

Alternate gene names: 159898321

Gene position: 2085790-2086776 (Clockwise)

Preceding gene: 159898320

Following gene: 159898323

Centisome position: 32.86

GC content: 51.47

Gene sequence:

>987_bases
ATGGATTATCGTGATTTAGGTCGAACTGGCTGGCAGATTTCGACGATTGGCTTTGGGGCATGGGCGATTGGCGGCGATGC
TTGGGGCAAAACCGACGATGCTACCTCGCTGGCCACAATTCACACAGCGATTGATGCTGGGGTGAATTTTATTGATACTG
CTGATGTCTATGGTGATGGCCATTCCGAGCGCCTGATTGCCCAAGTATTGCGTGAACGTCCAGGCGAGATTGTCGTTGCA
ACCAAGGCTGGTCGCCGTTTGAATCCGCATACAGCGGCTGGCTATAATCGCGAAAACCTAACTGCCTTTGTTGAACGTAG
TTTGCATAATTTGAATACCGAAGCCCTCGATTTGCTGCAACTGCATTGCCCACCAACCGACGTTTATTCAATGCCCGAAG
TCTTCGAGGTGCTTGATAATTTGGTGCGAGCTGGCAAGGTGCGTTACTACGGTGTAAGTGTCGAGCGCGTCGATGAGGCT
TTGGCCGCGATTGAATATCCCAATGTGCAAAGCGTGCAAATTATCTTCAATCTTTTTCGCTACAAACCAATTGAGCAATT
TTTTGCGGCGGCCAAAGCCAAGCGGGTTGGTATTCTGGCGCGGGTTCCCTTAGCCAGCGGTTTGCTATCAGGCAAAATCA
GCGCTGCAACCACGTTTGAAGCTAGCGATCATCGCAATTACAACCGCCATGGCGAATCGTTTGATCAAGGTGAAACCTTC
TCAGGGGTTGATTATGCTACCGGATTGCAAGCCGTTGAGGAATTACACGCTTTAGTGCCAATCGATGTCAGCATGGCCCA
ATTTGCCTTGCGCTGGATTTTGATGTTCGATGCGGTGACGACGGCAATTCCTGGGGCCAAAACGCCTGAACAAATGCGAG
CCAACGCTGCTGCTGCCGAGCTAGCCCCGCTCGATGCGGCAACCATGGCCCAAGCCCAAGCGATTTATGATCGTTTGATT
CGCCCGTTAGTGCACGAGCGCTGGTAA

Upstream 100 bases:

>100_bases
ACCCAAGTATTGCTGGTTTTGTTCTAGTAGTTTGTATCAACGCATCGAGCAATTGGCTATCCATGTTAAAATAGCTCATC
ATTACTTCCGAGGAGCGTGC

Downstream 100 bases:

>100_bases
CGAGTTTGGGATTAGGGATCAGAGGCTAGGGTTTAGGGAACGTGGTGGATTATTGACATGATGTTCTTCGATCCACGAAG
AGCACGAAGTTACACGAAGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDYRDLGRTGWQISTIGFGAWAIGGDAWGKTDDATSLATIHTAIDAGVNFIDTADVYGDGHSERLIAQVLRERPGEIVVA
TKAGRRLNPHTAAGYNRENLTAFVERSLHNLNTEALDLLQLHCPPTDVYSMPEVFEVLDNLVRAGKVRYYGVSVERVDEA
LAAIEYPNVQSVQIIFNLFRYKPIEQFFAAAKAKRVGILARVPLASGLLSGKISAATTFEASDHRNYNRHGESFDQGETF
SGVDYATGLQAVEELHALVPIDVSMAQFALRWILMFDAVTTAIPGAKTPEQMRANAAAAELAPLDAATMAQAQAIYDRLI
RPLVHERW

Sequences:

>Translated_328_residues
MDYRDLGRTGWQISTIGFGAWAIGGDAWGKTDDATSLATIHTAIDAGVNFIDTADVYGDGHSERLIAQVLRERPGEIVVA
TKAGRRLNPHTAAGYNRENLTAFVERSLHNLNTEALDLLQLHCPPTDVYSMPEVFEVLDNLVRAGKVRYYGVSVERVDEA
LAAIEYPNVQSVQIIFNLFRYKPIEQFFAAAKAKRVGILARVPLASGLLSGKISAATTFEASDHRNYNRHGESFDQGETF
SGVDYATGLQAVEELHALVPIDVSMAQFALRWILMFDAVTTAIPGAKTPEQMRANAAAAELAPLDAATMAQAQAIYDRLI
RPLVHERW
>Mature_328_residues
MDYRDLGRTGWQISTIGFGAWAIGGDAWGKTDDATSLATIHTAIDAGVNFIDTADVYGDGHSERLIAQVLRERPGEIVVA
TKAGRRLNPHTAAGYNRENLTAFVERSLHNLNTEALDLLQLHCPPTDVYSMPEVFEVLDNLVRAGKVRYYGVSVERVDEA
LAAIEYPNVQSVQIIFNLFRYKPIEQFFAAAKAKRVGILARVPLASGLLSGKISAATTFEASDHRNYNRHGESFDQGETF
SGVDYATGLQAVEELHALVPIDVSMAQFALRWILMFDAVTTAIPGAKTPEQMRANAAAAELAPLDAATMAQAQAIYDRLI
RPLVHERW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=318, Percent_Identity=25.4716981132075, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=25.4716981132075, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=25.1572327044025, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=24.5222929936306, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=24.3589743589744, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI27436971, Length=313, Percent_Identity=24.2811501597444, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=28.7878787878788, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788070, Length=338, Percent_Identity=27.5147928994083, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=26.7692307692308, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788081, Length=307, Percent_Identity=24.7557003257329, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789199, Length=366, Percent_Identity=24.8633879781421, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=335, Percent_Identity=23.8805970149254, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=307, Percent_Identity=26.3843648208469, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646159, Length=220, Percent_Identity=32.7272727272727, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24646155, Length=220, Percent_Identity=29.0909090909091, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36002; Mature: 36002

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRDLGRTGWQISTIGFGAWAIGGDAWGKTDDATSLATIHTAIDAGVNFIDTADVYGDG
CCCHHCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHCCCC
HSERLIAQVLRERPGEIVVATKAGRRLNPHTAAGYNRENLTAFVERSLHNLNTEALDLLQ
CHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LHCPPTDVYSMPEVFEVLDNLVRAGKVRYYGVSVERVDEALAAIEYPNVQSVQIIFNLFR
HCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YKPIEQFFAAAKAKRVGILARVPLASGLLSGKISAATTFEASDHRNYNRHGESFDQGETF
CCHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
SGVDYATGLQAVEELHALVPIDVSMAQFALRWILMFDAVTTAIPGAKTPEQMRANAAAAE
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LAPLDAATMAQAQAIYDRLIRPLVHERW
HCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYRDLGRTGWQISTIGFGAWAIGGDAWGKTDDATSLATIHTAIDAGVNFIDTADVYGDG
CCCHHCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHCCCC
HSERLIAQVLRERPGEIVVATKAGRRLNPHTAAGYNRENLTAFVERSLHNLNTEALDLLQ
CHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LHCPPTDVYSMPEVFEVLDNLVRAGKVRYYGVSVERVDEALAAIEYPNVQSVQIIFNLFR
HCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YKPIEQFFAAAKAKRVGILARVPLASGLLSGKISAATTFEASDHRNYNRHGESFDQGETF
CCHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
SGVDYATGLQAVEELHALVPIDVSMAQFALRWILMFDAVTTAIPGAKTPEQMRANAAAAE
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LAPLDAATMAQAQAIYDRLIRPLVHERW
HCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]