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The map label for this gene is rsbRA [H]

Identifier: 159898186

GI number: 159898186

Start: 1930637

End: 1931509

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_1662

Alternate gene names: 159898186

Gene position: 1930637-1931509 (Clockwise)

Preceding gene: 159898183

Following gene: 159898193

Centisome position: 30.42

GC content: 48.45

Gene sequence:

>873_bases
ATGAGCAATTCAGCATCAGATTCCGCCGCACTCCAGGCCCAAATTGCCGAATTACAGGCCCAATTAGCCCACGCCCAACG
CCAAGCCGAGTTATTTGAAAATCTGGTCAAACGCTTGCCAATTGGCATCGATTTGTTACAACGCGAAGATCCCAATGATC
CGACCTCGCTGCGCTTAATTTTTACCAATGGTTTGATGCCCAATGCACCGATTGATATGCGCCTCCACGTGGGCAAGTTG
ATTAAAGATATTTTCCCCGATGTGCCACCCATGGTTTTTGATCGCTATCAGCATGCGCTGGATTCAGGTGAGATGGTGCA
TTTGAATGAATTAACCGTCAAAGTGCCAGATATTGGGGTTCGAATTGCCCAGCTTTCAGCGATTCCGCTTACCAACGATA
TTTTGTGTATCAAAGTTGCCGATATTACCGAGCAAAAGCAGGTGCTCGAAGCCCAACGCCATATGATGGAGCAACAGGCG
ATTATTAATAGCCAACAGGAAGCATTGGCTGATATTTCAACTCCATTAATTCCAATTACCGATAGTGTGGTGATTATGCC
GCTGATTGGGGCGGTCGATACGCGGCGGGCACAGCAGATGATGGAAACTTTGCTGCATGGCATTAGTCACATGACCGCGC
GTTTTGCCATTTTGGATATTACTGGGGTGCCGATTGTGGATACTCAGGTGGCCCATGTGCTGATTCAAGCGGCGCAATCG
GTGCGTTTGCTTGGCGGTCAGGTTATTTTAACTGGCATTCGCCCAGAAGTTGCCCAAACCTTGGTTGGCTTGGGCGTGAA
TCTCAACGATTTGATTGTACGCGGCAATTTGCAAAGTGGTGTAGCCTATGCCACGCTTGAGCGCTATCATTAA

Upstream 100 bases:

>100_bases
CAATACCCTGTATATCTGAATGATTTCGCTGTTGGCTGACCTTTACTCGCTGCATCGTCGTGATCGTTGAACTCCTTTGT
ATCAACCTTGGAGCGTTGAC

Downstream 100 bases:

>100_bases
TCATGGTTGCGCTAGCCACGTAGCTAGCGCTGTTTGCTAAATAAAGTTGGTTTTGCGTTGTTGGACGACAAGTGTGATGC
CCAATAAACCTACGATAATC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSNSASDSAALQAQIAELQAQLAHAQRQAELFENLVKRLPIGIDLLQREDPNDPTSLRLIFTNGLMPNAPIDMRLHVGKL
IKDIFPDVPPMVFDRYQHALDSGEMVHLNELTVKVPDIGVRIAQLSAIPLTNDILCIKVADITEQKQVLEAQRHMMEQQA
IINSQQEALADISTPLIPITDSVVIMPLIGAVDTRRAQQMMETLLHGISHMTARFAILDITGVPIVDTQVAHVLIQAAQS
VRLLGGQVILTGIRPEVAQTLVGLGVNLNDLIVRGNLQSGVAYATLERYH

Sequences:

>Translated_290_residues
MSNSASDSAALQAQIAELQAQLAHAQRQAELFENLVKRLPIGIDLLQREDPNDPTSLRLIFTNGLMPNAPIDMRLHVGKL
IKDIFPDVPPMVFDRYQHALDSGEMVHLNELTVKVPDIGVRIAQLSAIPLTNDILCIKVADITEQKQVLEAQRHMMEQQA
IINSQQEALADISTPLIPITDSVVIMPLIGAVDTRRAQQMMETLLHGISHMTARFAILDITGVPIVDTQVAHVLIQAAQS
VRLLGGQVILTGIRPEVAQTLVGLGVNLNDLIVRGNLQSGVAYATLERYH
>Mature_289_residues
SNSASDSAALQAQIAELQAQLAHAQRQAELFENLVKRLPIGIDLLQREDPNDPTSLRLIFTNGLMPNAPIDMRLHVGKLI
KDIFPDVPPMVFDRYQHALDSGEMVHLNELTVKVPDIGVRIAQLSAIPLTNDILCIKVADITEQKQVLEAQRHMMEQQAI
INSQQEALADISTPLIPITDSVVIMPLIGAVDTRRAQQMMETLLHGISHMTARFAILDITGVPIVDTQVAHVLIQAAQSV
RLLGGQVILTGIRPEVAQTLVGLGVNLNDLIVRGNLQSGVAYATLERYH

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31790; Mature: 31658

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSASDSAALQAQIAELQAQLAHAQRQAELFENLVKRLPIGIDLLQREDPNDPTSLRLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEE
FTNGLMPNAPIDMRLHVGKLIKDIFPDVPPMVFDRYQHALDSGEMVHLNELTVKVPDIGV
EECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCE
RIAQLSAIPLTNDILCIKVADITEQKQVLEAQRHMMEQQAIINSQQEALADISTPLIPIT
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECC
DSVVIMPLIGAVDTRRAQQMMETLLHGISHMTARFAILDITGVPIVDTQVAHVLIQAAQS
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHHH
VRLLGGQVILTGIRPEVAQTLVGLGVNLNDLIVRGNLQSGVAYATLERYH
HHHHCCEEEEECCCHHHHHHHHHCCCCHHHEEEECCCCCCCEEHHHHHCC
>Mature Secondary Structure 
SNSASDSAALQAQIAELQAQLAHAQRQAELFENLVKRLPIGIDLLQREDPNDPTSLRLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEE
FTNGLMPNAPIDMRLHVGKLIKDIFPDVPPMVFDRYQHALDSGEMVHLNELTVKVPDIGV
EECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCE
RIAQLSAIPLTNDILCIKVADITEQKQVLEAQRHMMEQQAIINSQQEALADISTPLIPIT
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECC
DSVVIMPLIGAVDTRRAQQMMETLLHGISHMTARFAILDITGVPIVDTQVAHVLIQAAQS
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHHH
VRLLGGQVILTGIRPEVAQTLVGLGVNLNDLIVRGNLQSGVAYATLERYH
HHHHCCEEEEECCCHHHHHHHHHCCCCHHHEEEECCCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]