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The map label for this gene is clpB [H]

Identifier: 159897408

GI number: 159897408

Start: 1000501

End: 1002831

Strand: Direct

Name: clpB [H]

Synonym: Haur_0879

Alternate gene names: 159897408

Gene position: 1000501-1002831 (Clockwise)

Preceding gene: 159897407

Following gene: 159897409

Centisome position: 15.76

GC content: 48.99

Gene sequence:

>2331_bases
ATGGCGAATACGTTTGAACGGCTTAACCCCAACATTCAGCATATTATGTTGTTGGCCCAAGAAGAAGCTCGGAGCCTTAA
CCATAGTTTTTTAGGCCCAGAGCATTTACTATTGGGGCTATTGCGGCAAAAAGAGGGTCTTGCGGTGCAGATATTGCACG
AATTAGGGGTTTTCTACCCCCAAACTCGGCAGATTATTCAGACCATGATTACCCCGCATGCCCGTGATGAACAAACCTTA
CTTCCTGCCTACCTCCCGCTGGCCCCTCATACAAAAACCCTTTTGGATACTGCGGCACGGGAAGCTGATCAACTTAATCA
ACAGCAGATTGGGCCTGAACAGCTTCTTTTAGCTTTAGCCCGCGAGGCTAAGGGCTTTGTTCCCTATATTTTGGCACGTT
TAGGCCTGCATGGCAGCATTGTCTGCGATAGCTTGCACGCAGCCTTGCAGGCCAAAGCCACCGAGGTAGCTCCTGCGCAT
GCCGCCGATACTTCACTCCTAGCAAAATTAGGAATTAATCTGACGGAAGAAGCTCGCAATGGCCGACTAGACCCGGTGAT
TGGACGCAGCGCCGAGATTGAACGGACTATCCAAATTTTACGGCGACGCACCAAAAATAACGTTGTCTTAATTGGTGAGC
CAGGGGTTGGTAAGACGGCAATTGTTGAAGGTTTAGCGCAGCAATTGGCTCATGGCGCAATCCCATCGTTTCAAAAAACC
TCGGTTTGGTCGCTTGATGTTGGCTCACTTTTGGCGGGCGCGATTTATCGTGGGCAATTTGAGGAGCGCCTTAAAAGCGT
CATCGACCAAATTAGCGACCACGATGCGATTCTTTTCATTGATGAATTACATATGATCGTCGGGGCTGGCGCAAGCGAAA
ATACCGTTGATGCAGCGAATATGTTAAAGCCAGCTTTAGCTCGTGGCAAACTGCGGGTCATTGGTGCAACAACCTTTGAT
GAATATAGCCAGCATATCGAGAAAGATAGTGCTCTCAAACGGCGATTTCAGCCAATTGTCGTGCAGGAGCCAGGGATCGA
GGAAACGGTAACAATTTTACAGGGTATTCGTCCGAAATACGAAGCCCATCATGAGCTTAGCTTGAGCGACGAGGCTTTGT
ATACTGCGGCACGACTGGCTGCCCAATATATTCCTGATCTCTATTTGCCTGGCAAGGCGATTGATCTTCTGGATGAAGCG
GCGAGTCGAGTTTGGTATTATCGGCAACGCCAACTGGTAGCCCACGATGCGGCTTCCAGTGCTGAAGCGCCTACCACTGT
TGTTTGTGGGCGTGATGTGGCGCAAGTGCTTGCCATCCAAACAGGGATACCCTTAGCTCAACTTTTTTCCGATGGTCTCA
ACCGTATCGAAGATATTGAGCAGATTCTGAGTCAGCGGGTTATTGGTCAAGCCCAGGCAATTCGGGGGGTAACCAAAGCC
ATCCAACGCGCTTTTGCCGGACTTAAAACGAAGCAAGATCTGATCGGGGCTTTATTGTTCTTAGGGCCGTCAGGGGTCGG
CAAAACCGAGTTGAGCAAAGTCTTGGCGGAATATCTGCTTGGCAGTAACAAGGCACTTATCCGAATGGATATGAGCGAAT
ATGCTGAGGCCCATAGTGTCAGCCGCTTGATTGGTGCTCCGCCTGGCTATATTGGCTACGATCAGGGCGGTCAATTATCC
GAATCCGTTCGTCGCCGTCCGTATAGCGTTGTCTTGCTTGATAATATTGATTATGCCCATCCTGATGTGATCAATATATT
CATTCAAATCCTCGAAGAAGGCTCTATAACTGATGCGCGTGGGCGTTATGTTGATTTTCGAAATGTGTTGTTGTTGTGCA
CCGCAAACGTGGGTACTGAACTCTTTAAGCGCCAAACGGGGCTTGGTTTTAGAGCTGAGCTCCCTGAAATTGACCAAGTA
GCCCGCTATGAGCACTTGAAACAACAAGCACTTGACAAAATCAAAACCTCGCTGAGCCTCGATTTTCTCCATCGACTGAA
TGATGTGATTCTTTTTCAACCGCTCCAAGCTGAACACCTTGAAGTATTGGCGGGACTCTTCTTACAAGATGTTCGCCAGA
TGGTGCTAGCCCATGAAATTCGGCTCGACCTAACCTCAAATGCGCATACCTATTTGACGGATCATGGCTACGATCTTGAG
CGTGGGGTTCGACGCTTACGCCACCTCATCCAAACCCATATCGTTGATCCAATTAGCAATGGATTGCTCCATGGTAAATA
TCGGGCGGGTGATGAACTACTGATCGACTGTGATTTGAGTGGCAACTTTACCCTGTTGGTTGCTCAGCGCACAACGTCGG
TTGTCGCATAA

Upstream 100 bases:

>100_bases
TGATTACCTGCTGGCTCACCATCAGCATTGTTGGTCGCCATACAGCTAGCACGTAGGATTGAGCGTCGTTTGCAGCCTTT
GATTTGTGTGCGGTGGTACT

Downstream 100 bases:

>100_bases
AGGAAAAGCTATGACAGAAACACCATATTCAACCCACGTAGCAGGTTCGGCTAGTGGCAGCACTGATACAACGCAGCGCC
AAGCATGGATTATTGTGCTA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MANTFERLNPNIQHIMLLAQEEARSLNHSFLGPEHLLLGLLRQKEGLAVQILHELGVFYPQTRQIIQTMITPHARDEQTL
LPAYLPLAPHTKTLLDTAAREADQLNQQQIGPEQLLLALAREAKGFVPYILARLGLHGSIVCDSLHAALQAKATEVAPAH
AADTSLLAKLGINLTEEARNGRLDPVIGRSAEIERTIQILRRRTKNNVVLIGEPGVGKTAIVEGLAQQLAHGAIPSFQKT
SVWSLDVGSLLAGAIYRGQFEERLKSVIDQISDHDAILFIDELHMIVGAGASENTVDAANMLKPALARGKLRVIGATTFD
EYSQHIEKDSALKRRFQPIVVQEPGIEETVTILQGIRPKYEAHHELSLSDEALYTAARLAAQYIPDLYLPGKAIDLLDEA
ASRVWYYRQRQLVAHDAASSAEAPTTVVCGRDVAQVLAIQTGIPLAQLFSDGLNRIEDIEQILSQRVIGQAQAIRGVTKA
IQRAFAGLKTKQDLIGALLFLGPSGVGKTELSKVLAEYLLGSNKALIRMDMSEYAEAHSVSRLIGAPPGYIGYDQGGQLS
ESVRRRPYSVVLLDNIDYAHPDVINIFIQILEEGSITDARGRYVDFRNVLLLCTANVGTELFKRQTGLGFRAELPEIDQV
ARYEHLKQQALDKIKTSLSLDFLHRLNDVILFQPLQAEHLEVLAGLFLQDVRQMVLAHEIRLDLTSNAHTYLTDHGYDLE
RGVRRLRHLIQTHIVDPISNGLLHGKYRAGDELLIDCDLSGNFTLLVAQRTTSVVA

Sequences:

>Translated_776_residues
MANTFERLNPNIQHIMLLAQEEARSLNHSFLGPEHLLLGLLRQKEGLAVQILHELGVFYPQTRQIIQTMITPHARDEQTL
LPAYLPLAPHTKTLLDTAAREADQLNQQQIGPEQLLLALAREAKGFVPYILARLGLHGSIVCDSLHAALQAKATEVAPAH
AADTSLLAKLGINLTEEARNGRLDPVIGRSAEIERTIQILRRRTKNNVVLIGEPGVGKTAIVEGLAQQLAHGAIPSFQKT
SVWSLDVGSLLAGAIYRGQFEERLKSVIDQISDHDAILFIDELHMIVGAGASENTVDAANMLKPALARGKLRVIGATTFD
EYSQHIEKDSALKRRFQPIVVQEPGIEETVTILQGIRPKYEAHHELSLSDEALYTAARLAAQYIPDLYLPGKAIDLLDEA
ASRVWYYRQRQLVAHDAASSAEAPTTVVCGRDVAQVLAIQTGIPLAQLFSDGLNRIEDIEQILSQRVIGQAQAIRGVTKA
IQRAFAGLKTKQDLIGALLFLGPSGVGKTELSKVLAEYLLGSNKALIRMDMSEYAEAHSVSRLIGAPPGYIGYDQGGQLS
ESVRRRPYSVVLLDNIDYAHPDVINIFIQILEEGSITDARGRYVDFRNVLLLCTANVGTELFKRQTGLGFRAELPEIDQV
ARYEHLKQQALDKIKTSLSLDFLHRLNDVILFQPLQAEHLEVLAGLFLQDVRQMVLAHEIRLDLTSNAHTYLTDHGYDLE
RGVRRLRHLIQTHIVDPISNGLLHGKYRAGDELLIDCDLSGNFTLLVAQRTTSVVA
>Mature_775_residues
ANTFERLNPNIQHIMLLAQEEARSLNHSFLGPEHLLLGLLRQKEGLAVQILHELGVFYPQTRQIIQTMITPHARDEQTLL
PAYLPLAPHTKTLLDTAAREADQLNQQQIGPEQLLLALAREAKGFVPYILARLGLHGSIVCDSLHAALQAKATEVAPAHA
ADTSLLAKLGINLTEEARNGRLDPVIGRSAEIERTIQILRRRTKNNVVLIGEPGVGKTAIVEGLAQQLAHGAIPSFQKTS
VWSLDVGSLLAGAIYRGQFEERLKSVIDQISDHDAILFIDELHMIVGAGASENTVDAANMLKPALARGKLRVIGATTFDE
YSQHIEKDSALKRRFQPIVVQEPGIEETVTILQGIRPKYEAHHELSLSDEALYTAARLAAQYIPDLYLPGKAIDLLDEAA
SRVWYYRQRQLVAHDAASSAEAPTTVVCGRDVAQVLAIQTGIPLAQLFSDGLNRIEDIEQILSQRVIGQAQAIRGVTKAI
QRAFAGLKTKQDLIGALLFLGPSGVGKTELSKVLAEYLLGSNKALIRMDMSEYAEAHSVSRLIGAPPGYIGYDQGGQLSE
SVRRRPYSVVLLDNIDYAHPDVINIFIQILEEGSITDARGRYVDFRNVLLLCTANVGTELFKRQTGLGFRAELPEIDQVA
RYEHLKQQALDKIKTSLSLDFLHRLNDVILFQPLQAEHLEVLAGLFLQDVRQMVLAHEIRLDLTSNAHTYLTDHGYDLER
GVRRLRHLIQTHIVDPISNGLLHGKYRAGDELLIDCDLSGNFTLLVAQRTTSVVA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=4e-42,
Organism=Escherichia coli, GI1787109, Length=776, Percent_Identity=36.9845360824742, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1788943, Length=405, Percent_Identity=44.1975308641975, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6320464, Length=248, Percent_Identity=53.2258064516129, Blast_Score=267, Evalue=6e-72,
Organism=Saccharomyces cerevisiae, GI6323002, Length=406, Percent_Identity=39.6551724137931, Blast_Score=259, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 85687; Mature: 85555

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTFERLNPNIQHIMLLAQEEARSLNHSFLGPEHLLLGLLRQKEGLAVQILHELGVFYP
CCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
QTRQIIQTMITPHARDEQTLLPAYLPLAPHTKTLLDTAAREADQLNQQQIGPEQLLLALA
HHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
REAKGFVPYILARLGLHGSIVCDSLHAALQAKATEVAPAHAADTSLLAKLGINLTEEARN
HHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCC
GRLDPVIGRSAEIERTIQILRRRTKNNVVLIGEPGVGKTAIVEGLAQQLAHGAIPSFQKT
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
SVWSLDVGSLLAGAIYRGQFEERLKSVIDQISDHDAILFIDELHMIVGAGASENTVDAAN
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHH
MLKPALARGKLRVIGATTFDEYSQHIEKDSALKRRFQPIVVQEPGIEETVTILQGIRPKY
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCH
EAHHELSLSDEALYTAARLAAQYIPDLYLPGKAIDLLDEAASRVWYYRQRQLVAHDAASS
HCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEAPTTVVCGRDVAQVLAIQTGIPLAQLFSDGLNRIEDIEQILSQRVIGQAQAIRGVTKA
CCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQRAFAGLKTKQDLIGALLFLGPSGVGKTELSKVLAEYLLGSNKALIRMDMSEYAEAHSV
HHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
SRLIGAPPGYIGYDQGGQLSESVRRRPYSVVLLDNIDYAHPDVINIFIQILEEGSITDAR
HHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GRYVDFRNVLLLCTANVGTELFKRQTGLGFRAELPEIDQVARYEHLKQQALDKIKTSLSL
CCEEECCCEEEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DFLHRLNDVILFQPLQAEHLEVLAGLFLQDVRQMVLAHEIRLDLTSNAHTYLTDHGYDLE
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHH
RGVRRLRHLIQTHIVDPISNGLLHGKYRAGDELLIDCDLSGNFTLLVAQRTTSVVA
HHHHHHHHHHHHHHHCHHHCCCEECCCCCCCEEEEEEECCCCEEEEEEECCHHHCC
>Mature Secondary Structure 
ANTFERLNPNIQHIMLLAQEEARSLNHSFLGPEHLLLGLLRQKEGLAVQILHELGVFYP
CCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
QTRQIIQTMITPHARDEQTLLPAYLPLAPHTKTLLDTAAREADQLNQQQIGPEQLLLALA
HHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
REAKGFVPYILARLGLHGSIVCDSLHAALQAKATEVAPAHAADTSLLAKLGINLTEEARN
HHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCC
GRLDPVIGRSAEIERTIQILRRRTKNNVVLIGEPGVGKTAIVEGLAQQLAHGAIPSFQKT
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
SVWSLDVGSLLAGAIYRGQFEERLKSVIDQISDHDAILFIDELHMIVGAGASENTVDAAN
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHH
MLKPALARGKLRVIGATTFDEYSQHIEKDSALKRRFQPIVVQEPGIEETVTILQGIRPKY
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCH
EAHHELSLSDEALYTAARLAAQYIPDLYLPGKAIDLLDEAASRVWYYRQRQLVAHDAASS
HCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEAPTTVVCGRDVAQVLAIQTGIPLAQLFSDGLNRIEDIEQILSQRVIGQAQAIRGVTKA
CCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQRAFAGLKTKQDLIGALLFLGPSGVGKTELSKVLAEYLLGSNKALIRMDMSEYAEAHSV
HHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
SRLIGAPPGYIGYDQGGQLSESVRRRPYSVVLLDNIDYAHPDVINIFIQILEEGSITDAR
HHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GRYVDFRNVLLLCTANVGTELFKRQTGLGFRAELPEIDQVARYEHLKQQALDKIKTSLSL
CCEEECCCEEEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DFLHRLNDVILFQPLQAEHLEVLAGLFLQDVRQMVLAHEIRLDLTSNAHTYLTDHGYDLE
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHH
RGVRRLRHLIQTHIVDPISNGLLHGKYRAGDELLIDCDLSGNFTLLVAQRTTSVVA
HHHHHHHHHHHHHHHCHHHCCCEECCCCCCCEEEEEEECCCCEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]