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The map label for this gene is pnuC [H]

Identifier: 159897043

GI number: 159897043

Start: 596256

End: 596888

Strand: Reverse

Name: pnuC [H]

Synonym: Haur_0513

Alternate gene names: 159897043

Gene position: 596888-596256 (Counterclockwise)

Preceding gene: 159897044

Following gene: 159897042

Centisome position: 9.4

GC content: 47.08

Gene sequence:

>633_bases
ATGGATCTTGCGAGTTTCTTCGATATTAATACGATTGCCTTTACGCTCTTTGGCTACCCCATGAGCTATCTCGAATTAGC
TGGTACGATCTTCAATTTGTGGTCGGTGTGGCTGGTTGGGCGTGGGCGCATCAGCAATTGGCCAATTGGCTTAATCGGCG
TAGTGCTCTTCTTCGTGTTGTTCTACCAAATTCAACTCTATGCCGACACGTTTGAGCAAGTTTACTACTTTTTTACTGGC
ATTTACGGCTGGTGGCATTGGTCGAAGCCGAAAGAGCAAGCCGCCAAACCGCGTTACAGTTCGCGCAACTATAATCTGCT
GGCCTTGGGTATTACTGTGGTTGGCACGCTGATTTTAGCGTTTATTATTGGCAATCTTGATCAATGGCTGCCTGCCTATT
TTCCTGCACCCGCAACCTATGTTTTGATCGATTCGTTGACCACCGTGATGAGCTTTACGGCGACGATTTTGATGGCCCAA
CGCCGAATCGAATGTTGGTATTATTGGATTACGGTCGATGTGATTGCGATTTGGCTGTATAGCGTTAAGGGCACACTCTT
GGTCGCGCTGCTATATGCAATCTTTTTGGTATTGGCTAGCAATGGTTGGCGTTTATGGCGCAAAGCCAGTTAA

Upstream 100 bases:

>100_bases
TTAGCGGCCCGCTTGAGCAGCGCATCGCCCAAGTGCAAAGCTTATTACAACGCCATCAGCTTTATCACAATCTGCTTGCC
AACCCAGCCTGAGGTGTTTT

Downstream 100 bases:

>100_bases
ACAAAAAAACACCCTAGGGTGCTTTGTTTAAGTGTGGCGACTCCGGGGCGAGTCGAACGCCCGACCTTTTCCTCCGCAGG
GAAACGCTCTATCCACTGAG

Product: nicotinamide mononucleotide transporter PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MDLASFFDINTIAFTLFGYPMSYLELAGTIFNLWSVWLVGRGRISNWPIGLIGVVLFFVLFYQIQLYADTFEQVYYFFTG
IYGWWHWSKPKEQAAKPRYSSRNYNLLALGITVVGTLILAFIIGNLDQWLPAYFPAPATYVLIDSLTTVMSFTATILMAQ
RRIECWYYWITVDVIAIWLYSVKGTLLVALLYAIFLVLASNGWRLWRKAS

Sequences:

>Translated_210_residues
MDLASFFDINTIAFTLFGYPMSYLELAGTIFNLWSVWLVGRGRISNWPIGLIGVVLFFVLFYQIQLYADTFEQVYYFFTG
IYGWWHWSKPKEQAAKPRYSSRNYNLLALGITVVGTLILAFIIGNLDQWLPAYFPAPATYVLIDSLTTVMSFTATILMAQ
RRIECWYYWITVDVIAIWLYSVKGTLLVALLYAIFLVLASNGWRLWRKAS
>Mature_210_residues
MDLASFFDINTIAFTLFGYPMSYLELAGTIFNLWSVWLVGRGRISNWPIGLIGVVLFFVLFYQIQLYADTFEQVYYFFTG
IYGWWHWSKPKEQAAKPRYSSRNYNLLALGITVVGTLILAFIIGNLDQWLPAYFPAPATYVLIDSLTTVMSFTATILMAQ
RRIECWYYWITVDVIAIWLYSVKGTLLVALLYAIFLVLASNGWRLWRKAS

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=211, Percent_Identity=31.7535545023697, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 24305; Mature: 24305

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLASFFDINTIAFTLFGYPMSYLELAGTIFNLWSVWLVGRGRISNWPIGLIGVVLFFVL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
FYQIQLYADTFEQVYYFFTGIYGWWHWSKPKEQAAKPRYSSRNYNLLALGITVVGTLILA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
FIIGNLDQWLPAYFPAPATYVLIDSLTTVMSFTATILMAQRRIECWYYWITVDVIAIWLY
HHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKGTLLVALLYAIFLVLASNGWRLWRKAS
HHHHHHHHHHHHHHHHHHHCCCCEECCCCC
>Mature Secondary Structure
MDLASFFDINTIAFTLFGYPMSYLELAGTIFNLWSVWLVGRGRISNWPIGLIGVVLFFVL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
FYQIQLYADTFEQVYYFFTGIYGWWHWSKPKEQAAKPRYSSRNYNLLALGITVVGTLILA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
FIIGNLDQWLPAYFPAPATYVLIDSLTTVMSFTATILMAQRRIECWYYWITVDVIAIWLY
HHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKGTLLVALLYAIFLVLASNGWRLWRKAS
HHHHHHHHHHHHHHHHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]