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The map label for this gene is opuCB [H]

Identifier: 159896884

GI number: 159896884

Start: 422850

End: 423488

Strand: Direct

Name: opuCB [H]

Synonym: Haur_0352

Alternate gene names: 159896884

Gene position: 422850-423488 (Clockwise)

Preceding gene: 159896883

Following gene: 159896886

Centisome position: 6.66

GC content: 49.3

Gene sequence:

>639_bases
ATGAACGACATCGTTGATGGACTCCGATATCTATTAACTGAACGGGCTGAGGTTTGGCAATTGCTTGGCCAGCATGTAAC
GATCAGCCTGATCGCGCTCTTGATCGCTAGCTTGATTGCCTTGCCGCTGGGGGTATTGGTGGTGCGGGTTGGTTGGCTGG
CTGGTGGTGTGATGGCCGTGTTGAGTGTGCTCTATACAATTCCTAGTTTGGCAATGCTGATTATGCTGATTGCAGTGTTT
GGCCTGAGCAAAACCACCGTGATCGTGACGCTGGTGATCTATGCCCAAGTGATTTTGGTGCGCAACATTGTGGTTGGCTT
GAAGAGCATTGATCGCTCGGTGCTTGAAGCGGCGCGAGGTTTGGGCATGAATGCTTGGCAAATTTGGTGGCAAGTCGAAT
TGCCTTTAGCTTTGCCAATTATGTTGGCCGGCCTGCGGATTGCCGCCATGATGTGTATTGCGATTAGTTCAATTGCTGCA
ATGATTGGTGTTGGTGGATTGGGGCAGTTATTGTTTCAAGGCATCACCTTTGATCGGGCTGATATGATTTGGGCGGGCAC
AATCAGCATTGCCAGCTTGGCCTTGGTTTGTTATGGATTATTGGCTTTGGTGGAGCAACGATTTAGCCCAAAAATATAA

Upstream 100 bases:

>100_bases
GCCAGCAGCGACGAACAATTGTTGGTCGTTGAACACAATCAACCAATTGGTATGCTCTCATTAGCCGCAATTCATGCCTA
TTTGCACCCTGAGGTCATCC

Downstream 100 bases:

>100_bases
TTGGAGCCGCGACCAGCTTGCAATAGCCATTGCAACATATCGCTAGCTCCAATTATAGCCAAACCATACGATAGCTACTA
GCAGCGCCGAAGCGCAATTA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNDIVDGLRYLLTERAEVWQLLGQHVTISLIALLIASLIALPLGVLVVRVGWLAGGVMAVLSVLYTIPSLAMLIMLIAVF
GLSKTTVIVTLVIYAQVILVRNIVVGLKSIDRSVLEAARGLGMNAWQIWWQVELPLALPIMLAGLRIAAMMCIAISSIAA
MIGVGGLGQLLFQGITFDRADMIWAGTISIASLALVCYGLLALVEQRFSPKI

Sequences:

>Translated_212_residues
MNDIVDGLRYLLTERAEVWQLLGQHVTISLIALLIASLIALPLGVLVVRVGWLAGGVMAVLSVLYTIPSLAMLIMLIAVF
GLSKTTVIVTLVIYAQVILVRNIVVGLKSIDRSVLEAARGLGMNAWQIWWQVELPLALPIMLAGLRIAAMMCIAISSIAA
MIGVGGLGQLLFQGITFDRADMIWAGTISIASLALVCYGLLALVEQRFSPKI
>Mature_212_residues
MNDIVDGLRYLLTERAEVWQLLGQHVTISLIALLIASLIALPLGVLVVRVGWLAGGVMAVLSVLYTIPSLAMLIMLIAVF
GLSKTTVIVTLVIYAQVILVRNIVVGLKSIDRSVLEAARGLGMNAWQIWWQVELPLALPIMLAGLRIAAMMCIAISSIAA
MIGVGGLGQLLFQGITFDRADMIWAGTISIASLALVCYGLLALVEQRFSPKI

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=221, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789033, Length=145, Percent_Identity=32.4137931034483, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788449, Length=128, Percent_Identity=34.375, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22779; Mature: 22779

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIVDGLRYLLTERAEVWQLLGQHVTISLIALLIASLIALPLGVLVVRVGWLAGGVMAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVLYTIPSLAMLIMLIAVFGLSKTTVIVTLVIYAQVILVRNIVVGLKSIDRSVLEAARG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGMNAWQIWWQVELPLALPIMLAGLRIAAMMCIAISSIAAMIGVGGLGQLLFQGITFDRA
CCCCHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCH
DMIWAGTISIASLALVCYGLLALVEQRFSPKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDIVDGLRYLLTERAEVWQLLGQHVTISLIALLIASLIALPLGVLVVRVGWLAGGVMAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVLYTIPSLAMLIMLIAVFGLSKTTVIVTLVIYAQVILVRNIVVGLKSIDRSVLEAARG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGMNAWQIWWQVELPLALPIMLAGLRIAAMMCIAISSIAAMIGVGGLGQLLFQGITFDRA
CCCCHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCH
DMIWAGTISIASLALVCYGLLALVEQRFSPKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]