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The map label for this gene is fusA [H]

Identifier: 159896822

GI number: 159896822

Start: 340088

End: 342199

Strand: Direct

Name: fusA [H]

Synonym: Haur_0289

Alternate gene names: 159896822

Gene position: 340088-342199 (Clockwise)

Preceding gene: 159896821

Following gene: 159896824

Centisome position: 5.36

GC content: 52.51

Gene sequence:

>2112_bases
ATGAAAGAGTACGGTCCGGATCGTATCCACACAATTGGCCTCTTTGGCCATGGCGGTGCTGGCAAAACTACCCTCGCTGA
AGCCCTACTTTTCGCCAGCAAAGCTCTCCCACGGATGGGTCGCGTCGAAGATGGCTCGACGGTTAGCGATTACGACCCCG
ATGAAGTCAAGCGCCATGCCTCAATTAACCTCTCGGTGATTCCGATCGAATGGAATGGCAACAAGTTCAATTTTATCGAT
GTGCCTGGCTATGCCGATTTCCGGGGTGAAGCCGCTGCGGCGCTCCGTGTGATCGATGGGATGGTGCTGGTGCTCGATGC
GGCTGGCGGGGTGGAAGTTGGCGCAGAATTACTTTGGCAAATGGCTCGTGAGGCGAATATCCCACGGGTCGTTTTTATTA
ACAAGCTTGATCGCGAAAATGCCAATTTCCAGCGGACTGTCGAACAAGCCAAGGGTCTGTTGAGCGAGGCAATCACGCCT
GTGCATATGCCAATCGGCAGCGGAGCCAACTTCAAGGGCATCGTGTCGCTACGCAAACGCAAAGCATGGCTGCATCACAA
TGGCAAAGATGGCGCGTATGAAATTGCCGAAATTCCCGCCGAAATTCGCCAAGAAGCGCTGCAAATGGCCGATGGCTTGA
TCGAAAAAATCGCCATGACCAACGACCACCTGATCGAAGAATATTTAGAAGGTGGAGCCGATGCCCTGAGTGCCGAGGAA
ATTCGCCAAGGCTTTCAAGCGGCAATCAATGCGCATACGATTATGCCGCTGTTTATTGGCTCGGCCACCACGCTTTCGGG
CATTCCCCAGTTGCTCGATGGGATTCTCGATGCGATTCCTTCGGCGGCCAATCGCTTGACGACCGCCCACGATTTGCGCA
ACGATGATGATTATTTCCTTGAAGGCAAGGCTGATGAGCCACTGAGCGCTTTAGTGTTCAAAACCTTGGTTGACCAATAT
GTTGGGCGCTTGAGTTTCTTCCGCGTGTTTAGCGGCGAAATTCATTCCAACTCAGTGGTGCGTAATGCTCGTACAGGCCG
CGAAGAGCGGATTGGCCAGCTCTTTCAGATGCGCGGCAAGGAGCAAACGCCTGTCTCCTCGGTGAGCGCTGGCGATTTGG
GAGCTGTGGCCAAACTCGCTGATACGCTCAGCGGCGACACGCTTTACAATCCTGAAAACCCTTTACGTTTACGCAGTGTT
AGCTACCCCGAAGCTGCTTTTACCGCCAAAGTTACGCCTCATTCCAAAAACGACCTCGATAAGTTGGGCAATGCATTGCA
TCGGATCGTCGAAGAAGACCCCACCTTGCACCTCGGACGCGACATCCAAACTGGCGAAACCTTGCTTGCTGGTTTGAGCG
AAACCCACCTGAATTTTGTGGCCGAGCGAGTCAAACGCAAATTCGATGTGCATTTTGATTTGGCAATACCTAGCGTGCCC
TATCGCGAACGCATCAGCAGCACCGCTACTGCCACCTATCGCCACAAAAAACAAACAGGTGGGGCTGGGCAATTTGCCGA
AATTTCGCTGCGGCTCGAACCATTGCCAACTGACCCGAATCGTGCTGATCCATTGGAATTTGTCAGCGAGATTGTGGGGG
GCGTGGTTTCACGGTCGTTCTGGCCAGCGATTGAAAAGGGTATCCGTGAATCGATGGCCTTGGGCGTGCTTTCTGGCCAT
CCAGTGATCGACGTGAAAGCAGCGATTTACGATGGCAAGGAACATCCCGTCGATAGCAAAGAAATTGCCTTCAAAACCGC
TGGTAAATTTGCCTTCCGCGAGGCCGCGCGTAAAGCCAACCCAGTTATTATCGAGCCAATTTATGCCTTGAAAATCAATG
TGCCCGATGAATATGTTGGCGATATTCTAAGCGATTTGAATGGCAACAAACGTGGGCGAGTGCAAGGTATGGAGCAAATC
GGCCATAGTCGCACCTTGATCACAGCCCACGTGCCATTAGCTGAATGCCAGCGTTATGCTACCGATTTGCGCTCAATTAC
CCAAGGCCGTGGCGATTTTGTGATGCGGCTTGATCACTATGATGATGTGCCACATAGCGTTGCCCAAACGATCATTGCCA
ACTCCAAACAGCAACACGACGATGATGAGTAG

Upstream 100 bases:

>100_bases
CTAGGCTTGCCGTTCGGCCACGACGGCGCTATAATCGACAAACAATCAACCTCACATTGATTCCGTCGTCGTTTCAAGTA
ACTCCAAAGGAGGAGTCTCT

Downstream 100 bases:

>100_bases
GGTTGATAAGGATGAATTATGAAGGATGAGGGATGAAATAGTGATCCACGAAGGACACGAAGGAATACCAAGCAGAAGCC
TGCCTTCGTGTCCTTCGTGT

Product: small GTP-binding protein

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MKEYGPDRIHTIGLFGHGGAGKTTLAEALLFASKALPRMGRVEDGSTVSDYDPDEVKRHASINLSVIPIEWNGNKFNFID
VPGYADFRGEAAAALRVIDGMVLVLDAAGGVEVGAELLWQMAREANIPRVVFINKLDRENANFQRTVEQAKGLLSEAITP
VHMPIGSGANFKGIVSLRKRKAWLHHNGKDGAYEIAEIPAEIRQEALQMADGLIEKIAMTNDHLIEEYLEGGADALSAEE
IRQGFQAAINAHTIMPLFIGSATTLSGIPQLLDGILDAIPSAANRLTTAHDLRNDDDYFLEGKADEPLSALVFKTLVDQY
VGRLSFFRVFSGEIHSNSVVRNARTGREERIGQLFQMRGKEQTPVSSVSAGDLGAVAKLADTLSGDTLYNPENPLRLRSV
SYPEAAFTAKVTPHSKNDLDKLGNALHRIVEEDPTLHLGRDIQTGETLLAGLSETHLNFVAERVKRKFDVHFDLAIPSVP
YRERISSTATATYRHKKQTGGAGQFAEISLRLEPLPTDPNRADPLEFVSEIVGGVVSRSFWPAIEKGIRESMALGVLSGH
PVIDVKAAIYDGKEHPVDSKEIAFKTAGKFAFREAARKANPVIIEPIYALKINVPDEYVGDILSDLNGNKRGRVQGMEQI
GHSRTLITAHVPLAECQRYATDLRSITQGRGDFVMRLDHYDDVPHSVAQTIIANSKQQHDDDE

Sequences:

>Translated_703_residues
MKEYGPDRIHTIGLFGHGGAGKTTLAEALLFASKALPRMGRVEDGSTVSDYDPDEVKRHASINLSVIPIEWNGNKFNFID
VPGYADFRGEAAAALRVIDGMVLVLDAAGGVEVGAELLWQMAREANIPRVVFINKLDRENANFQRTVEQAKGLLSEAITP
VHMPIGSGANFKGIVSLRKRKAWLHHNGKDGAYEIAEIPAEIRQEALQMADGLIEKIAMTNDHLIEEYLEGGADALSAEE
IRQGFQAAINAHTIMPLFIGSATTLSGIPQLLDGILDAIPSAANRLTTAHDLRNDDDYFLEGKADEPLSALVFKTLVDQY
VGRLSFFRVFSGEIHSNSVVRNARTGREERIGQLFQMRGKEQTPVSSVSAGDLGAVAKLADTLSGDTLYNPENPLRLRSV
SYPEAAFTAKVTPHSKNDLDKLGNALHRIVEEDPTLHLGRDIQTGETLLAGLSETHLNFVAERVKRKFDVHFDLAIPSVP
YRERISSTATATYRHKKQTGGAGQFAEISLRLEPLPTDPNRADPLEFVSEIVGGVVSRSFWPAIEKGIRESMALGVLSGH
PVIDVKAAIYDGKEHPVDSKEIAFKTAGKFAFREAARKANPVIIEPIYALKINVPDEYVGDILSDLNGNKRGRVQGMEQI
GHSRTLITAHVPLAECQRYATDLRSITQGRGDFVMRLDHYDDVPHSVAQTIIANSKQQHDDDE
>Mature_703_residues
MKEYGPDRIHTIGLFGHGGAGKTTLAEALLFASKALPRMGRVEDGSTVSDYDPDEVKRHASINLSVIPIEWNGNKFNFID
VPGYADFRGEAAAALRVIDGMVLVLDAAGGVEVGAELLWQMAREANIPRVVFINKLDRENANFQRTVEQAKGLLSEAITP
VHMPIGSGANFKGIVSLRKRKAWLHHNGKDGAYEIAEIPAEIRQEALQMADGLIEKIAMTNDHLIEEYLEGGADALSAEE
IRQGFQAAINAHTIMPLFIGSATTLSGIPQLLDGILDAIPSAANRLTTAHDLRNDDDYFLEGKADEPLSALVFKTLVDQY
VGRLSFFRVFSGEIHSNSVVRNARTGREERIGQLFQMRGKEQTPVSSVSAGDLGAVAKLADTLSGDTLYNPENPLRLRSV
SYPEAAFTAKVTPHSKNDLDKLGNALHRIVEEDPTLHLGRDIQTGETLLAGLSETHLNFVAERVKRKFDVHFDLAIPSVP
YRERISSTATATYRHKKQTGGAGQFAEISLRLEPLPTDPNRADPLEFVSEIVGGVVSRSFWPAIEKGIRESMALGVLSGH
PVIDVKAAIYDGKEHPVDSKEIAFKTAGKFAFREAARKANPVIIEPIYALKINVPDEYVGDILSDLNGNKRGRVQGMEQI
GHSRTLITAHVPLAECQRYATDLRSITQGRGDFVMRLDHYDDVPHSVAQTIIANSKQQHDDDE

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=698, Percent_Identity=32.9512893982808, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI19923640, Length=710, Percent_Identity=30.2816901408451, Blast_Score=295, Evalue=1e-79,
Organism=Homo sapiens, GI25306287, Length=710, Percent_Identity=28.7323943661972, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI25306283, Length=391, Percent_Identity=33.2480818414322, Blast_Score=189, Evalue=8e-48,
Organism=Homo sapiens, GI94966754, Length=163, Percent_Identity=30.0613496932515, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789738, Length=696, Percent_Identity=36.3505747126437, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1790835, Length=470, Percent_Identity=25.1063829787234, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI48994988, Length=174, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17533571, Length=704, Percent_Identity=30.5397727272727, Blast_Score=345, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17556745, Length=719, Percent_Identity=24.8956884561892, Blast_Score=206, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17557151, Length=178, Percent_Identity=29.2134831460674, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=704, Percent_Identity=33.0965909090909, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6322359, Length=796, Percent_Identity=24.6231155778894, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6324707, Length=178, Percent_Identity=28.0898876404494, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320593, Length=178, Percent_Identity=28.0898876404494, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24582462, Length=708, Percent_Identity=33.3333333333333, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI221458488, Length=719, Percent_Identity=25.452016689847, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24585711, Length=817, Percent_Identity=22.6438188494492, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585713, Length=817, Percent_Identity=22.6438188494492, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585709, Length=817, Percent_Identity=22.6438188494492, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 77046; Mature: 77046

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYGPDRIHTIGLFGHGGAGKTTLAEALLFASKALPRMGRVEDGSTVSDYDPDEVKRHA
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
SINLSVIPIEWNGNKFNFIDVPGYADFRGEAAAALRVIDGMVLVLDAAGGVEVGAELLWQ
CCEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
MAREANIPRVVFINKLDRENANFQRTVEQAKGLLSEAITPVHMPIGSGANFKGIVSLRKR
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHH
KAWLHHNGKDGAYEIAEIPAEIRQEALQMADGLIEKIAMTNDHLIEEYLEGGADALSAEE
HHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHH
IRQGFQAAINAHTIMPLFIGSATTLSGIPQLLDGILDAIPSAANRLTTAHDLRNDDDYFL
HHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
EGKADEPLSALVFKTLVDQYVGRLSFFRVFSGEIHSNSVVRNARTGREERIGQLFQMRGK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHCCC
EQTPVSSVSAGDLGAVAKLADTLSGDTLYNPENPLRLRSVSYPEAAFTAKVTPHSKNDLD
CCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCEEEECCCCCHHEEEEECCCCCCHHH
KLGNALHRIVEEDPTLHLGRDIQTGETLLAGLSETHLNFVAERVKRKFDVHFDLAIPSVP
HHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
YRERISSTATATYRHKKQTGGAGQFAEISLRLEPLPTDPNRADPLEFVSEIVGGVVSRSF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
WPAIEKGIRESMALGVLSGHPVIDVKAAIYDGKEHPVDSKEIAFKTAGKFAFREAARKAN
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PVIIEPIYALKINVPDEYVGDILSDLNGNKRGRVQGMEQIGHSRTLITAHVPLAECQRYA
CEEEEEEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHH
TDLRSITQGRGDFVMRLDHYDDVPHSVAQTIIANSKQQHDDDE
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKEYGPDRIHTIGLFGHGGAGKTTLAEALLFASKALPRMGRVEDGSTVSDYDPDEVKRHA
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
SINLSVIPIEWNGNKFNFIDVPGYADFRGEAAAALRVIDGMVLVLDAAGGVEVGAELLWQ
CCEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
MAREANIPRVVFINKLDRENANFQRTVEQAKGLLSEAITPVHMPIGSGANFKGIVSLRKR
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHH
KAWLHHNGKDGAYEIAEIPAEIRQEALQMADGLIEKIAMTNDHLIEEYLEGGADALSAEE
HHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHH
IRQGFQAAINAHTIMPLFIGSATTLSGIPQLLDGILDAIPSAANRLTTAHDLRNDDDYFL
HHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
EGKADEPLSALVFKTLVDQYVGRLSFFRVFSGEIHSNSVVRNARTGREERIGQLFQMRGK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHCCC
EQTPVSSVSAGDLGAVAKLADTLSGDTLYNPENPLRLRSVSYPEAAFTAKVTPHSKNDLD
CCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCEEEECCCCCHHEEEEECCCCCCHHH
KLGNALHRIVEEDPTLHLGRDIQTGETLLAGLSETHLNFVAERVKRKFDVHFDLAIPSVP
HHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
YRERISSTATATYRHKKQTGGAGQFAEISLRLEPLPTDPNRADPLEFVSEIVGGVVSRSF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
WPAIEKGIRESMALGVLSGHPVIDVKAAIYDGKEHPVDSKEIAFKTAGKFAFREAARKAN
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PVIIEPIYALKINVPDEYVGDILSDLNGNKRGRVQGMEQIGHSRTLITAHVPLAECQRYA
CEEEEEEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHH
TDLRSITQGRGDFVMRLDHYDDVPHSVAQTIIANSKQQHDDDE
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA