Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 159896753

GI number: 159896753

Start: 256057

End: 257043

Strand: Direct

Name: trpS [H]

Synonym: Haur_0220

Alternate gene names: 159896753

Gene position: 256057-257043 (Clockwise)

Preceding gene: 159896746

Following gene: 159896760

Centisome position: 4.03

GC content: 50.56

Gene sequence:

>987_bases
ATGGGTTCGTTACCACGGGTTTTTTCGGGCATTCAACCATCAGGCAATTTGCACCTTGGCAACTATTTGGGGGCGATTCA
TACCTGGGTGCAAGAGCAAAATCAATACGATAATTTCTTCTGTATTGTCGATCTGCATGCGATCACCGTGCCACAAGATC
CAGCCGAGTTGCGCAAAAATGTGCGCGATTTGGCCGCGCTGTATCTGGCCGCAGGCATTAGCCTTGAGCATGCCACGATT
TTTGTCCAATCGCATGTGCCAGCTCACGTTGAGCTAGGCTGGATTTTAAATTGTCAAACGCCCTTGGGCTGGTTGAATCG
CATGACCCAATTTAAGGATAAATCGCAAAAGCAAGAAACCGTAGCGGCTGGCTTGATGAATTATCCAACGCTGATGGCTG
CTGATATTTTGCTCTACGACACCCAAGTTGTGCCAGTGGGCGACGATCAACGTCAGCATATTGAGCTAACTCGCGATATT
GCCGAGCGTTTTAATCATCTTTATGGCGAAACCTTTGTCATCCCCGAGGCCTTGATTCGGCCTGTGGCGGCGCGGGTGAT
GGGCCTCGACGACCCAACCCAGAAGATGAGCAAGAGCAACAAAGCAGCCAATCATTCAATTCCTTTGTTGGGCGATTTGA
AGGCAACGCGCAAGGCCATGATGCGGGCAGTCACCGATTCGGGCAGCGAAATCAAATTCGACGAAACCCGACCTGGGGTC
AACAATCTTTTGGGGATTTATCAAGCCTTGACTGGCAAAGACAAAGCCACGATTGAGGCTGAATTTGAAGGCCAAGGCTA
TGGCAAACTCAAAGGTGCAGTTGCCGATGTGGTGATCGCTACCTTGGAGCCATTGCAACAACGCTACAATCAACTCACCG
CTGATCCAGCTGAACTCGATGGGATTCTCAAACGTGGCGCTGAACGCGCTGCCGAAGTTGCTAACGCTACCTTGTTACGG
GCTTATCAACAACTTGGGCTGCGCTAA

Upstream 100 bases:

>100_bases
GGTTGCGAATTCGGGTGGTACCGCGAGAATCAAGCCGTCTCTCGTCCCGTATGTGGATTCGAGAGACGGCCTTGTTTTAG
TTAGACGGAGTGTTGCCATT

Downstream 100 bases:

>100_bases
TTCTTAACGAGGTCAGTTTTTGATCCACGAAGGACACGAAGAGCACGAAGACTGCTTTTTAGCCACAGATTGGCACAGAT
TGGCACAGATTTTTGTGATT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MGSLPRVFSGIQPSGNLHLGNYLGAIHTWVQEQNQYDNFFCIVDLHAITVPQDPAELRKNVRDLAALYLAAGISLEHATI
FVQSHVPAHVELGWILNCQTPLGWLNRMTQFKDKSQKQETVAAGLMNYPTLMAADILLYDTQVVPVGDDQRQHIELTRDI
AERFNHLYGETFVIPEALIRPVAARVMGLDDPTQKMSKSNKAANHSIPLLGDLKATRKAMMRAVTDSGSEIKFDETRPGV
NNLLGIYQALTGKDKATIEAEFEGQGYGKLKGAVADVVIATLEPLQQRYNQLTADPAELDGILKRGAERAAEVANATLLR
AYQQLGLR

Sequences:

>Translated_328_residues
MGSLPRVFSGIQPSGNLHLGNYLGAIHTWVQEQNQYDNFFCIVDLHAITVPQDPAELRKNVRDLAALYLAAGISLEHATI
FVQSHVPAHVELGWILNCQTPLGWLNRMTQFKDKSQKQETVAAGLMNYPTLMAADILLYDTQVVPVGDDQRQHIELTRDI
AERFNHLYGETFVIPEALIRPVAARVMGLDDPTQKMSKSNKAANHSIPLLGDLKATRKAMMRAVTDSGSEIKFDETRPGV
NNLLGIYQALTGKDKATIEAEFEGQGYGKLKGAVADVVIATLEPLQQRYNQLTADPAELDGILKRGAERAAEVANATLLR
AYQQLGLR
>Mature_327_residues
GSLPRVFSGIQPSGNLHLGNYLGAIHTWVQEQNQYDNFFCIVDLHAITVPQDPAELRKNVRDLAALYLAAGISLEHATIF
VQSHVPAHVELGWILNCQTPLGWLNRMTQFKDKSQKQETVAAGLMNYPTLMAADILLYDTQVVPVGDDQRQHIELTRDIA
ERFNHLYGETFVIPEALIRPVAARVMGLDDPTQKMSKSNKAANHSIPLLGDLKATRKAMMRAVTDSGSEIKFDETRPGVN
NLLGIYQALTGKDKATIEAEFEGQGYGKLKGAVADVVIATLEPLQQRYNQLTADPAELDGILKRGAERAAEVANATLLRA
YQQLGLR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=315, Percent_Identity=43.1746031746032, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=53.9772727272727, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI1789786, Length=327, Percent_Identity=54.1284403669725, Blast_Score=343, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI71982800, Length=329, Percent_Identity=34.6504559270517, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71982793, Length=329, Percent_Identity=34.6504559270517, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320474, Length=346, Percent_Identity=38.150289017341, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24666151, Length=325, Percent_Identity=42.7692307692308, Blast_Score=244, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36197; Mature: 36066

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLPRVFSGIQPSGNLHLGNYLGAIHTWVQEQNQYDNFFCIVDLHAITVPQDPAELRKN
CCCCCHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCHHHHHHH
VRDLAALYLAAGISLEHATIFVQSHVPAHVELGWILNCQTPLGWLNRMTQFKDKSQKQET
HHHHHHHHHHHCCCEEHEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
VAAGLMNYPTLMAADILLYDTQVVPVGDDQRQHIELTRDIAERFNHLYGETFVIPEALIR
HHHHHHCCHHHHHHHHHEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHH
PVAARVMGLDDPTQKMSKSNKAANHSIPLLGDLKATRKAMMRAVTDSGSEIKFDETRPGV
HHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
NNLLGIYQALTGKDKATIEAEFEGQGYGKLKGAVADVVIATLEPLQQRYNQLTADPAELD
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GILKRGAERAAEVANATLLRAYQQLGLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSLPRVFSGIQPSGNLHLGNYLGAIHTWVQEQNQYDNFFCIVDLHAITVPQDPAELRKN
CCCCHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCHHHHHHH
VRDLAALYLAAGISLEHATIFVQSHVPAHVELGWILNCQTPLGWLNRMTQFKDKSQKQET
HHHHHHHHHHHCCCEEHEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
VAAGLMNYPTLMAADILLYDTQVVPVGDDQRQHIELTRDIAERFNHLYGETFVIPEALIR
HHHHHHCCHHHHHHHHHEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHH
PVAARVMGLDDPTQKMSKSNKAANHSIPLLGDLKATRKAMMRAVTDSGSEIKFDETRPGV
HHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
NNLLGIYQALTGKDKATIEAEFEGQGYGKLKGAVADVVIATLEPLQQRYNQLTADPAELD
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GILKRGAERAAEVANATLLRAYQQLGLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]