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The map label for this gene is dtd

Identifier: 159896719

GI number: 159896719

Start: 215792

End: 216253

Strand: Direct

Name: dtd

Synonym: Haur_0186

Alternate gene names: 159896719

Gene position: 215792-216253 (Clockwise)

Preceding gene: 159896718

Following gene: 159896720

Centisome position: 3.4

GC content: 50.87

Gene sequence:

>462_bases
ATGCGGGCAATTATCCAGCGCGTAGCTAATGCCAGCGTTACCGTTGCTGAGCAGATTGTCGGCCAAATTGAGACTGGCTT
GTTGGTGTTGCTGGCAGTGAGTCCTAGCGATACTAGCGACGATTTGCAAAAACTTGCTGATAAGATCCTCAATTTGCGGA
TTTTTCCTGATGCCCACGATCGTTTTGATCGCTCGTTGATTGATTGCCAAGGCCAATTACTGGTGGTTTCACAATTTACG
TTGTATGCCGACACGCGCAAGGGTCGCAGGCCATCGTTTACTGGGGCGGCGGCTCCAGCGTTGGCTGAGCCAATGGTTGA
CCAATTTATTGCCTATTGTCGTGGACAAGGCATTACGACGGCGAGTGGTCAATTTGGCGCAGCGATGCAGGTTCAACTGA
TTAATGATGGCCCAGTCACGATTATTTTGGATACAGCGGAGTGGCAGCATGGCCGAGGTTGA

Upstream 100 bases:

>100_bases
GTTCGGGTGATCGTCAGCCGGGTCTGGACGAACGATCGTGGTCGCATGGTCTTTGGGCGAATTATGGGCAGTGCTGGAGC
ATTTTACGGGGGCAAAAACG

Downstream 100 bases:

>100_bases
TGATTCTGAGCAGGTGTTGGTGCAATTGGCGCAGAGCTTGCATCGCCATCGCCTGAGCGGAGTCGCACAGTTGTTTCTAC
GCTCGGGCCATGTTGCTAGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRAIIQRVANASVTVAEQIVGQIETGLLVLLAVSPSDTSDDLQKLADKILNLRIFPDAHDRFDRSLIDCQGQLLVVSQFT
LYADTRKGRRPSFTGAAAPALAEPMVDQFIAYCRGQGITTASGQFGAAMQVQLINDGPVTIILDTAEWQHGRG

Sequences:

>Translated_153_residues
MRAIIQRVANASVTVAEQIVGQIETGLLVLLAVSPSDTSDDLQKLADKILNLRIFPDAHDRFDRSLIDCQGQLLVVSQFT
LYADTRKGRRPSFTGAAAPALAEPMVDQFIAYCRGQGITTASGQFGAAMQVQLINDGPVTIILDTAEWQHGRG
>Mature_153_residues
MRAIIQRVANASVTVAEQIVGQIETGLLVLLAVSPSDTSDDLQKLADKILNLRIFPDAHDRFDRSLIDCQGQLLVVSQFT
LYADTRKGRRPSFTGAAAPALAEPMVDQFIAYCRGQGITTASGQFGAAMQVQLINDGPVTIILDTAEWQHGRG

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=41.2162162162162, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=48.2517482517483, Blast_Score=137, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=39.3333333333333, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=36.4864864864865, Blast_Score=111, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=44, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_HERA2 (A9B6D5)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001542966.1
- ProteinModelPortal:   A9B6D5
- SMR:   A9B6D5
- GeneID:   5732032
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_0186
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- BioCyc:   HAUR316274:HAUR_0186-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16540; Mature: 16540

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIIQRVANASVTVAEQIVGQIETGLLVLLAVSPSDTSDDLQKLADKILNLRIFPDAHD
CHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHEEEECCCCHH
RFDRSLIDCQGQLLVVSQFTLYADTRKGRRPSFTGAAAPALAEPMVDQFIAYCRGQGITT
HHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
ASGQFGAAMQVQLINDGPVTIILDTAEWQHGRG
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MRAIIQRVANASVTVAEQIVGQIETGLLVLLAVSPSDTSDDLQKLADKILNLRIFPDAHD
CHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHEEEECCCCHH
RFDRSLIDCQGQLLVVSQFTLYADTRKGRRPSFTGAAAPALAEPMVDQFIAYCRGQGITT
HHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
ASGQFGAAMQVQLINDGPVTIILDTAEWQHGRG
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA