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The map label for this gene is oxyR [H]

Identifier: 159896566

GI number: 159896566

Start: 41857

End: 42765

Strand: Direct

Name: oxyR [H]

Synonym: Haur_0033

Alternate gene names: 159896566

Gene position: 41857-42765 (Clockwise)

Preceding gene: 159896564

Following gene: 159896567

Centisome position: 0.66

GC content: 48.07

Gene sequence:

>909_bases
ATGGAAATTCATCAATTGCTCTATTTTGTGGCGGTCGCTGAAACTGGTGGTTTTAGTCGGGCTGCCCAACGTTGCGCCGT
TAGCCAACCTTCGCTCAGCCAACAAATTATTAAATTGGAGCATGAACTCGGTCAAGCGCTGTTTGAACGTTTGGGTCGCA
CGATTCGCTTAACCACCGCGGGCCAAGCACTTTTGCCGCAAGCGCAGCAATTGCTCACCCAATGGCGTTCGATCAAACAA
CATGTTAGTGATAGTGTCGAGCAGCACGCTTGTCGTTTGGCAATTGGAATTATTCCGACGTTGGCTCCACGCTTTTTTCC
GAACGTCAGCCAAGCCTTTCAACACCATTTTCCCCGAACAACATTAAGCATAGTTGAACATACGACGAGCCAATTATTAA
TTCAACTAATCGAATATAGCCTCGATTTGCTAATTGCCAGCGGGCCGATTGAGCATCCGTTGATCCAGATTGAGCCTTTA
TTTGATGAAGTGTTGCTGGTAGCATTACCACACGATCATCAATATGCTCAGCGTTCGGTTTTGCAATTAAATGATTTATA
TCACATGCCGCTGCTGGCGTTACACGATGACCATTGTTTGAGCCAACAAGTTGATGCCTTTTGCTACGAACAATATTTGG
AGCCGCAAGTGGTTGGGCGAGTCACCAATTTAACCACGATTCAACGCTGTGTAGCCGCAGGCTTGGGCATGGCGTTTGTA
CCACAATCACTCACCCAAGCCGAGCCGCATCCCAATGTGGTCTATCGGCGTTTGCTCGATGCCCAGCCACAACGCAAGAT
CATCGCCGCATGGCATCATCAACGCCCACCAAGCAGCAGTGTGCTCGATTTATTGCGCACAAACCTTGGAGCAAGTCAAA
AGGCAGAAGTCAAAAGGCAAAAGAGTTAA

Upstream 100 bases:

>100_bases
TACAGGCGTTGGTGTGCAGACCATGCCTACAACTATACTGTATGCTATTATATCCATAGTTGCAACATCTTATTAACTAT
ACAATCTATAGGCAACAACT

Downstream 100 bases:

>100_bases
AGGGTGAGAGGGGTCAGGGGCTAGGGGTCAGGAGTAAGCATAGAACAGAGTGAATGCTGTGGCGGGTTGGAAATAGCAAA
AGAATAATTCGTGCAATCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEIHQLLYFVAVAETGGFSRAAQRCAVSQPSLSQQIIKLEHELGQALFERLGRTIRLTTAGQALLPQAQQLLTQWRSIKQ
HVSDSVEQHACRLAIGIIPTLAPRFFPNVSQAFQHHFPRTTLSIVEHTTSQLLIQLIEYSLDLLIASGPIEHPLIQIEPL
FDEVLLVALPHDHQYAQRSVLQLNDLYHMPLLALHDDHCLSQQVDAFCYEQYLEPQVVGRVTNLTTIQRCVAAGLGMAFV
PQSLTQAEPHPNVVYRRLLDAQPQRKIIAAWHHQRPPSSSVLDLLRTNLGASQKAEVKRQKS

Sequences:

>Translated_302_residues
MEIHQLLYFVAVAETGGFSRAAQRCAVSQPSLSQQIIKLEHELGQALFERLGRTIRLTTAGQALLPQAQQLLTQWRSIKQ
HVSDSVEQHACRLAIGIIPTLAPRFFPNVSQAFQHHFPRTTLSIVEHTTSQLLIQLIEYSLDLLIASGPIEHPLIQIEPL
FDEVLLVALPHDHQYAQRSVLQLNDLYHMPLLALHDDHCLSQQVDAFCYEQYLEPQVVGRVTNLTTIQRCVAAGLGMAFV
PQSLTQAEPHPNVVYRRLLDAQPQRKIIAAWHHQRPPSSSVLDLLRTNLGASQKAEVKRQKS
>Mature_302_residues
MEIHQLLYFVAVAETGGFSRAAQRCAVSQPSLSQQIIKLEHELGQALFERLGRTIRLTTAGQALLPQAQQLLTQWRSIKQ
HVSDSVEQHACRLAIGIIPTLAPRFFPNVSQAFQHHFPRTTLSIVEHTTSQLLIQLIEYSLDLLIASGPIEHPLIQIEPL
FDEVLLVALPHDHQYAQRSVLQLNDLYHMPLLALHDDHCLSQQVDAFCYEQYLEPQVVGRVTNLTTIQRCVAAGLGMAFV
PQSLTQAEPHPNVVYRRLLDAQPQRKIIAAWHHQRPPSSSVLDLLRTNLGASQKAEVKRQKS

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=37.5451263537906, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI157672245, Length=220, Percent_Identity=34.0909090909091, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788887, Length=275, Percent_Identity=30.9090909090909, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787879, Length=257, Percent_Identity=31.1284046692607, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693105, Length=253, Percent_Identity=24.5059288537549, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367136, Length=272, Percent_Identity=28.3088235294118, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=27.5303643724696, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=24.8, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787601, Length=221, Percent_Identity=27.1493212669683, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787530, Length=257, Percent_Identity=24.5136186770428, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786401, Length=159, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788296, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786713, Length=301, Percent_Identity=24.5847176079734, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=217, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=166, Percent_Identity=26.5060240963855, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=239, Percent_Identity=23.8493723849372, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790208, Length=254, Percent_Identity=25.1968503937008, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994962, Length=150, Percent_Identity=31.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=265, Percent_Identity=24.1509433962264, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34014; Mature: 34014

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS50931 HTH_LYSR ; PS00602 ALDOLASE_CLASS_II_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIHQLLYFVAVAETGGFSRAAQRCAVSQPSLSQQIIKLEHELGQALFERLGRTIRLTTA
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GQALLPQAQQLLTQWRSIKQHVSDSVEQHACRLAIGIIPTLAPRFFPNVSQAFQHHFPRT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHH
TLSIVEHTTSQLLIQLIEYSLDLLIASGPIEHPLIQIEPLFDEVLLVALPHDHQYAQRSV
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHH
LQLNDLYHMPLLALHDDHCLSQQVDAFCYEQYLEPQVVGRVTNLTTIQRCVAAGLGMAFV
HHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
PQSLTQAEPHPNVVYRRLLDAQPQRKIIAAWHHQRPPSSSVLDLLRTNLGASQKAEVKRQ
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHC
KS
CC
>Mature Secondary Structure
MEIHQLLYFVAVAETGGFSRAAQRCAVSQPSLSQQIIKLEHELGQALFERLGRTIRLTTA
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GQALLPQAQQLLTQWRSIKQHVSDSVEQHACRLAIGIIPTLAPRFFPNVSQAFQHHFPRT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHH
TLSIVEHTTSQLLIQLIEYSLDLLIASGPIEHPLIQIEPLFDEVLLVALPHDHQYAQRSV
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHH
LQLNDLYHMPLLALHDDHCLSQQVDAFCYEQYLEPQVVGRVTNLTTIQRCVAAGLGMAFV
HHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
PQSLTQAEPHPNVVYRRLLDAQPQRKIIAAWHHQRPPSSSVLDLLRTNLGASQKAEVKRQ
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]