Click here to switch to the map view.

The map label for this gene is 159041955

Identifier: 159041955

GI number: 159041955

Start: 1468330

End: 1469883

Strand: Reverse

Name: 159041955

Synonym: Cmaq_1391

Alternate gene names: NA

Gene position: 1469883-1468330 (Counterclockwise)

Preceding gene: 159041956

Following gene: 159041951

Centisome position: 70.75

GC content: 47.88

Gene sequence:

>1554_bases
ATGGTATCCTGGGAAATAATCTACAGGGCATCAGTATTCATAGCTGAGGAAATGGGTGTGGCATTGAAGCGCTCGGCCTT
TTCCCCAAATATCCGTGAGAGGATGGATCACAGTTGCGCAATTACTGATGAGGATGGGAATATCATTGCCCAAGCCGAGC
ACATACCCGTTCACCTGGGTTCCTTTAAGATTGGTGTTAGGAATCTTTTAGACTGGTTATCCAGGGAGGGTGTTGAGCTT
AGGCAGGGTGACGCCGTTGTCTTGAATGACCCGTATATTTCAGGGACACATTTAAACGACGTTATGGTTACTCAACCCAT
ATACCACGGCAGTAGGTTGGTGGGTTACGTTGTTAATAAGGCTCACCACGTTGATGTAGGCGGCCCCGTACCCGGTAGTA
TTAATCCAAACGCCAGGACACTGTATGAGGAGGGTTTAATACTGCCTCCCGTTAAGATAATGGATAACGGTGAACTCAAG
CGTGATGTCCTTAACATAATATTGAGTAATTTCAAAACAACTGAGGCTGCTCTCGGGGACATTATGGCTCAATTATCAGC
CAACTCAGTGGGTGTATCTAGGGTTGCGGAGTTGATTAGTAAGTATGGTGTCGATGAGGTTGTTAACTCATGGAGGGAGA
GCATTACATACGGTAGGAGGCTGAGTCTACTTGAAATTAGTAAGTGGCCTAGGGGTGATTATAATGCTGTTGACTACATG
GAGTTGGGGGATGAATTACTACCCATAAGGGTTAAGGTTAGTATTAACGATGAGGGCATTACCGCGGACTTCTCTGGGAC
GCATGGGCAGGTGGATGCCCCGATAAATGCGGTTTACGGTGTAACCTTCTCAGCGGTCTCATTCGCCATTAGATCCTTGA
TTCAAACCGATGTACCAACCAATGAAGGCTTCTACAGTGTAATCAATGTTAATGCACCTGAAGGCACCCTGGTTAACCCA
AGGAAACCAGCCCCAGTCTCAGGGGGTAATGTGGAGACCACCCAGAGGATTGCGGATGTGGTTTTTAAGGCATTAGCCAA
TGCACTACCTAACAGTGTCCCAGCAGCCGGCTCCGGAACCATGATGAATATCATGATTGGCGGCGCATTACCCAATGGAG
GCTACTGGGCTTACTATGAAACAGTGGGTGGAGGCACTGGTGGTAGGCCTGGGAAACCTGGTGTGAGTGGTGTTCATGTT
AATATGACTAACACCTTGAATACACCCATTGAGATTGCTGAGAGGCAGTACCCATTATTATTCACGGCTTACAGGATTAG
GGAGGGTAGTGGTGGTTACGGTAAGTATAAGGGTGGTGATGGGGTGGTTAGGTCATTTAAGGTGTTAACTAAGGCTAGGC
TCTCAATAATGGCTGAGAGATTCAGGACTAGGCCGTGGGGATTACAGGGTGGTGGAGATGGGAAACCAGGTAGGGTTACT
GTGAGGAGGCTTAATGGTGTTGAGGAATTACCAAGTAAAGTAACCATTGACCTGGAGCCTGGGGATGAGGTCATAGTTGA
GACACCTGGTGGTGGGGGTTGGGGTAGTGGTTAG

Upstream 100 bases:

>100_bases
CCAGCCGTAATTGAGGAGTATGGTTCAACAATAGTGGTGCCGCCTAGGTGGAGGGCTGAGGTTGGTGGGAATGCGGAGGT
GATTATGAGGAGGTGACGCC

Downstream 100 bases:

>100_bases
GCTAGTTAATGGTGAGCTTTGATATGAAGAAGCCTTCAGCATTATGAATATGGGGCATTACCCTACCCACAACGCTTGAT
ACAGGGTAATTCACGTAACC

Product: 5-oxoprolinase

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MVSWEIIYRASVFIAEEMGVALKRSAFSPNIRERMDHSCAITDEDGNIIAQAEHIPVHLGSFKIGVRNLLDWLSREGVEL
RQGDAVVLNDPYISGTHLNDVMVTQPIYHGSRLVGYVVNKAHHVDVGGPVPGSINPNARTLYEEGLILPPVKIMDNGELK
RDVLNIILSNFKTTEAALGDIMAQLSANSVGVSRVAELISKYGVDEVVNSWRESITYGRRLSLLEISKWPRGDYNAVDYM
ELGDELLPIRVKVSINDEGITADFSGTHGQVDAPINAVYGVTFSAVSFAIRSLIQTDVPTNEGFYSVINVNAPEGTLVNP
RKPAPVSGGNVETTQRIADVVFKALANALPNSVPAAGSGTMMNIMIGGALPNGGYWAYYETVGGGTGGRPGKPGVSGVHV
NMTNTLNTPIEIAERQYPLLFTAYRIREGSGGYGKYKGGDGVVRSFKVLTKARLSIMAERFRTRPWGLQGGGDGKPGRVT
VRRLNGVEELPSKVTIDLEPGDEVIVETPGGGGWGSG

Sequences:

>Translated_517_residues
MVSWEIIYRASVFIAEEMGVALKRSAFSPNIRERMDHSCAITDEDGNIIAQAEHIPVHLGSFKIGVRNLLDWLSREGVEL
RQGDAVVLNDPYISGTHLNDVMVTQPIYHGSRLVGYVVNKAHHVDVGGPVPGSINPNARTLYEEGLILPPVKIMDNGELK
RDVLNIILSNFKTTEAALGDIMAQLSANSVGVSRVAELISKYGVDEVVNSWRESITYGRRLSLLEISKWPRGDYNAVDYM
ELGDELLPIRVKVSINDEGITADFSGTHGQVDAPINAVYGVTFSAVSFAIRSLIQTDVPTNEGFYSVINVNAPEGTLVNP
RKPAPVSGGNVETTQRIADVVFKALANALPNSVPAAGSGTMMNIMIGGALPNGGYWAYYETVGGGTGGRPGKPGVSGVHV
NMTNTLNTPIEIAERQYPLLFTAYRIREGSGGYGKYKGGDGVVRSFKVLTKARLSIMAERFRTRPWGLQGGGDGKPGRVT
VRRLNGVEELPSKVTIDLEPGDEVIVETPGGGGWGSG
>Mature_517_residues
MVSWEIIYRASVFIAEEMGVALKRSAFSPNIRERMDHSCAITDEDGNIIAQAEHIPVHLGSFKIGVRNLLDWLSREGVEL
RQGDAVVLNDPYISGTHLNDVMVTQPIYHGSRLVGYVVNKAHHVDVGGPVPGSINPNARTLYEEGLILPPVKIMDNGELK
RDVLNIILSNFKTTEAALGDIMAQLSANSVGVSRVAELISKYGVDEVVNSWRESITYGRRLSLLEISKWPRGDYNAVDYM
ELGDELLPIRVKVSINDEGITADFSGTHGQVDAPINAVYGVTFSAVSFAIRSLIQTDVPTNEGFYSVINVNAPEGTLVNP
RKPAPVSGGNVETTQRIADVVFKALANALPNSVPAAGSGTMMNIMIGGALPNGGYWAYYETVGGGTGGRPGKPGVSGVHV
NMTNTLNTPIEIAERQYPLLFTAYRIREGSGGYGKYKGGDGVVRSFKVLTKARLSIMAERFRTRPWGLQGGGDGKPGRVT
VRRLNGVEELPSKVTIDLEPGDEVIVETPGGGGWGSG

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=535, Percent_Identity=36.2616822429907, Blast_Score=291, Evalue=7e-79,
Organism=Caenorhabditis elegans, GI133901900, Length=526, Percent_Identity=37.0722433460076, Blast_Score=318, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI133901902, Length=510, Percent_Identity=36.078431372549, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6322634, Length=536, Percent_Identity=34.1417910447761, Blast_Score=290, Evalue=3e-79,
Organism=Drosophila melanogaster, GI45550492, Length=535, Percent_Identity=37.196261682243, Blast_Score=306, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 55659; Mature: 55659

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSWEIIYRASVFIAEEMGVALKRSAFSPNIRERMDHSCAITDEDGNIIAQAEHIPVHLG
CCEEEEEEEEEEEEHHHHCHHHHHCCCCCCHHHHCCCCEEEECCCCCEEEEECCCEEEEC
SFKIGVRNLLDWLSREGVELRQGDAVVLNDPYISGTHLNDVMVTQPIYHGSRLVGYVVNK
CEEHHHHHHHHHHHCCCCEEECCCEEEEECCEECCCCCCCEEEECCCCCCCHHEEHHHCC
AHHVDVGGPVPGSINPNARTLYEEGLILPPVKIMDNGELKRDVLNIILSNFKTTEAALGD
CEEEECCCCCCCCCCCCHHHHHHCCEECCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHH
IMAQLSANSVGVSRVAELISKYGVDEVVNSWRESITYGRRLSLLEISKWPRGDYNAVDYM
HHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHH
ELGDELLPIRVKVSINDEGITADFSGTHGQVDAPINAVYGVTFSAVSFAIRSLIQTDVPT
HCCCCEEEEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
NEGFYSVINVNAPEGTLVNPRKPAPVSGGNVETTQRIADVVFKALANALPNSVPAAGSGT
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MMNIMIGGALPNGGYWAYYETVGGGTGGRPGKPGVSGVHVNMTNTLNTPIEIAERQYPLL
EEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCCEE
FTAYRIREGSGGYGKYKGGDGVVRSFKVLTKARLSIMAERFRTRPWGLQGGGDGKPGRVT
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
VRRLNGVEELPSKVTIDLEPGDEVIVETPGGGGWGSG
EEECCCHHHCCCEEEEEECCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MVSWEIIYRASVFIAEEMGVALKRSAFSPNIRERMDHSCAITDEDGNIIAQAEHIPVHLG
CCEEEEEEEEEEEEHHHHCHHHHHCCCCCCHHHHCCCCEEEECCCCCEEEEECCCEEEEC
SFKIGVRNLLDWLSREGVELRQGDAVVLNDPYISGTHLNDVMVTQPIYHGSRLVGYVVNK
CEEHHHHHHHHHHHCCCCEEECCCEEEEECCEECCCCCCCEEEECCCCCCCHHEEHHHCC
AHHVDVGGPVPGSINPNARTLYEEGLILPPVKIMDNGELKRDVLNIILSNFKTTEAALGD
CEEEECCCCCCCCCCCCHHHHHHCCEECCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHH
IMAQLSANSVGVSRVAELISKYGVDEVVNSWRESITYGRRLSLLEISKWPRGDYNAVDYM
HHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHH
ELGDELLPIRVKVSINDEGITADFSGTHGQVDAPINAVYGVTFSAVSFAIRSLIQTDVPT
HCCCCEEEEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
NEGFYSVINVNAPEGTLVNPRKPAPVSGGNVETTQRIADVVFKALANALPNSVPAAGSGT
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MMNIMIGGALPNGGYWAYYETVGGGTGGRPGKPGVSGVHVNMTNTLNTPIEIAERQYPLL
EEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCCEE
FTAYRIREGSGGYGKYKGGDGVVRSFKVLTKARLSIMAERFRTRPWGLQGGGDGKPGRVT
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
VRRLNGVEELPSKVTIDLEPGDEVIVETPGGGGWGSG
EEECCCHHHCCCEEEEEECCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]