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The map label for this gene is uidA [H]

Identifier: 159041950

GI number: 159041950

Start: 1461550

End: 1463226

Strand: Reverse

Name: uidA [H]

Synonym: Cmaq_1386

Alternate gene names: 159041950

Gene position: 1463226-1461550 (Counterclockwise)

Preceding gene: 159041951

Following gene: 159041948

Centisome position: 70.43

GC content: 44.66

Gene sequence:

>1677_bases
ATGGTTACTGGTGTTAGACCTAGGATACCTTTGGATGGTTTTTGGGGTTTCAGGCTTGATCCTGGTAATGCCGGTGAGTC
TAATGGTTGGTTTAAGGGTTTTGAGTCCAGTGATCATATTTATGTTCCAGCCTCCTGGAATGAGCAGAATCCTGATTGGG
ATGGTTACAGTGGTGTTGCATGGTACTTAATGGACTTCTACGTGCCTAGGGAGCTTAATGGCTTAACACCATGGATAATC
TTCGAGGGTAGTGGTTACTTGAGTAGGGTTTGGGTTAATGGGGTATTTATTGGTGAGCATGAGGGTTCATTCACATTATT
CAAATTCAAGATACCCAACCTAAACTACGGTGGTTGGAATAGGGTCGTTGTTAAGATTGATAACACATTGAAGCCCGATA
ACATACCACCCGGTGAGGGTTTGAATGCAACCTACTTCGACTTCTACCATTACGGCGGTATTCAGAGGCCTGTTTGGGTT
GAGTTCACCCACGGCTGCTTCATTGATGATTTAATCATTGCCACTAGGCATGATGGATACCTTAAGGTTCAGCCAGTGGT
TAATTGCTCAAGGCCCTTTAAACTTGAGTTAAGCCTACTGGATAAGTCTGGTGGCGTGGTTTACAGTAGGGTTGTTGAGG
GTGCCTTTGAGGATTATGTTAAGGGTCTTGAACCATGGTCCATTGAACACCCTGTACTCTACACTCTTGAGGCTAGGTTA
ATTACTAATAATGATGTTGAGGACACCGTCACTGAGCGTATTGGGTTTAGGACATTTGAGGTTAAGGCTGGTGGATTCTA
CCTTAACGGTGAATCAATCTTCCTTAAGGGTTTCGGTAGGCATGAGGATTACCCAATATTCGGTAGGGCATTACCGGGGC
CAGTGTTGATTAGGGATTACTATAATATGAGGAGGATTAACGCCAACTCCTTCAGGACAAGTCACTACCCATACTCCAAC
GCCCACCTAGACCTAGCTGATGAATTCGGCGTACTCGTAATCCTAGAGGCACCATTGGTTGGGCTTAGGGAGCATCACTT
CAGTAACCGTGATTACCTTGAGAAGGCTAAGCGGGTTATTAGTGAGATGATTAGGCAGCATAGGAATAGGCCCAGTGTGG
TTATGTATAGTGTTGCTAATGAACCAAACAGTATTACTGATGAGGCTAGGGTATTCCTAGGTGAGTTAATGAACCATGTT
AAGTCCATTGACCCCACTAGACCAGTAATATATACTTCATTCAGGCACCTTGACGATAAGGCGCTGGGTCTTGGTGATGC
AGTGGCCTTAAACATATACTTCGGGTGGTATAGTGATACTGGTGATGTTGAAACTGGCGTGGCTAAGGCTGTTAAGCTTA
TTGAGGAGGTTCACTCAAGGTACCCTGATAAACCAATAATAATAACGGAGTTTGGTGCTGAGGGGGTTACTGGACTACAC
CATGACCCACCAGTGGCTTGGAGTGAGGAGTACCAGGAATTATTCCTAAGGAGGTATATTGAGGAATTATCAAAGAAACC
ATACGTAAGGGGATTACACATATGGAACTACGCAGACTTCAGGACCCCACAGAACCCAAGGAGGGTGATACTGAATACTA
AGGGCTTATACACCAGGGATAGGAGACCTAAGTTAGCCACTAGGACTGTGGCTGAGTTATTCTCAAAATTAAAGTAA

Upstream 100 bases:

>100_bases
GGCAACGACACGCCCATACACCTCTTCAAAGTAATTAACTAAATTACCGGTTGAACATAATTAACATTAATGCTTTAAAA
CTCGCTGATGCTCTGTAATT

Downstream 100 bases:

>100_bases
CACCATAACCACCTCATTCCTTGATTGGGGTAATGAAGTTACTGATTTACTGCGCTGAATAATTCTATCCTTATTCATTA
TTAAAAGCAATAATTTATGA

Product: beta-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MVTGVRPRIPLDGFWGFRLDPGNAGESNGWFKGFESSDHIYVPASWNEQNPDWDGYSGVAWYLMDFYVPRELNGLTPWII
FEGSGYLSRVWVNGVFIGEHEGSFTLFKFKIPNLNYGGWNRVVVKIDNTLKPDNIPPGEGLNATYFDFYHYGGIQRPVWV
EFTHGCFIDDLIIATRHDGYLKVQPVVNCSRPFKLELSLLDKSGGVVYSRVVEGAFEDYVKGLEPWSIEHPVLYTLEARL
ITNNDVEDTVTERIGFRTFEVKAGGFYLNGESIFLKGFGRHEDYPIFGRALPGPVLIRDYYNMRRINANSFRTSHYPYSN
AHLDLADEFGVLVILEAPLVGLREHHFSNRDYLEKAKRVISEMIRQHRNRPSVVMYSVANEPNSITDEARVFLGELMNHV
KSIDPTRPVIYTSFRHLDDKALGLGDAVALNIYFGWYSDTGDVETGVAKAVKLIEEVHSRYPDKPIIITEFGAEGVTGLH
HDPPVAWSEEYQELFLRRYIEELSKKPYVRGLHIWNYADFRTPQNPRRVILNTKGLYTRDRRPKLATRTVAELFSKLK

Sequences:

>Translated_558_residues
MVTGVRPRIPLDGFWGFRLDPGNAGESNGWFKGFESSDHIYVPASWNEQNPDWDGYSGVAWYLMDFYVPRELNGLTPWII
FEGSGYLSRVWVNGVFIGEHEGSFTLFKFKIPNLNYGGWNRVVVKIDNTLKPDNIPPGEGLNATYFDFYHYGGIQRPVWV
EFTHGCFIDDLIIATRHDGYLKVQPVVNCSRPFKLELSLLDKSGGVVYSRVVEGAFEDYVKGLEPWSIEHPVLYTLEARL
ITNNDVEDTVTERIGFRTFEVKAGGFYLNGESIFLKGFGRHEDYPIFGRALPGPVLIRDYYNMRRINANSFRTSHYPYSN
AHLDLADEFGVLVILEAPLVGLREHHFSNRDYLEKAKRVISEMIRQHRNRPSVVMYSVANEPNSITDEARVFLGELMNHV
KSIDPTRPVIYTSFRHLDDKALGLGDAVALNIYFGWYSDTGDVETGVAKAVKLIEEVHSRYPDKPIIITEFGAEGVTGLH
HDPPVAWSEEYQELFLRRYIEELSKKPYVRGLHIWNYADFRTPQNPRRVILNTKGLYTRDRRPKLATRTVAELFSKLK
>Mature_558_residues
MVTGVRPRIPLDGFWGFRLDPGNAGESNGWFKGFESSDHIYVPASWNEQNPDWDGYSGVAWYLMDFYVPRELNGLTPWII
FEGSGYLSRVWVNGVFIGEHEGSFTLFKFKIPNLNYGGWNRVVVKIDNTLKPDNIPPGEGLNATYFDFYHYGGIQRPVWV
EFTHGCFIDDLIIATRHDGYLKVQPVVNCSRPFKLELSLLDKSGGVVYSRVVEGAFEDYVKGLEPWSIEHPVLYTLEARL
ITNNDVEDTVTERIGFRTFEVKAGGFYLNGESIFLKGFGRHEDYPIFGRALPGPVLIRDYYNMRRINANSFRTSHYPYSN
AHLDLADEFGVLVILEAPLVGLREHHFSNRDYLEKAKRVISEMIRQHRNRPSVVMYSVANEPNSITDEARVFLGELMNHV
KSIDPTRPVIYTSFRHLDDKALGLGDAVALNIYFGWYSDTGDVETGVAKAVKLIEEVHSRYPDKPIIITEFGAEGVTGLH
HDPPVAWSEEYQELFLRRYIEELSKKPYVRGLHIWNYADFRTPQNPRRVILNTKGLYTRDRRPKLATRTVAELFSKLK

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=592, Percent_Identity=36.3175675675676, Blast_Score=325, Evalue=9e-89,
Organism=Escherichia coli, GI1787903, Length=583, Percent_Identity=33.1046312178388, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI48994920, Length=574, Percent_Identity=25.4355400696864, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786539, Length=453, Percent_Identity=24.9448123620309, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17510825, Length=596, Percent_Identity=29.5302013422819, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI19922582, Length=591, Percent_Identity=33.3333333333333, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24655438, Length=591, Percent_Identity=33.3333333333333, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI62471735, Length=591, Percent_Identity=33.3333333333333, Blast_Score=287, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24651745, Length=585, Percent_Identity=31.7948717948718, Blast_Score=248, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 64040; Mature: 64040

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGVRPRIPLDGFWGFRLDPGNAGESNGWFKGFESSDHIYVPASWNEQNPDWDGYSGVA
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHH
WYLMDFYVPRELNGLTPWIIFEGSGYLSRVWVNGVFIGEHEGSFTLFKFKIPNLNYGGWN
HHHHHHHCCHHCCCCCCEEEEECCCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCE
RVVVKIDNTLKPDNIPPGEGLNATYFDFYHYGGIQRPVWVEFTHGCFIDDLIIATRHDGY
EEEEEECCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCE
LKVQPVVNCSRPFKLELSLLDKSGGVVYSRVVEGAFEDYVKGLEPWSIEHPVLYTLEARL
EEEEEEECCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
ITNNDVEDTVTERIGFRTFEVKAGGFYLNGESIFLKGFGRHEDYPIFGRALPGPVLIRDY
EECCCHHHHHHHHHCCEEEEEEECCEEECCCEEEEEECCCCCCCCEECCCCCCCEEEECC
YNMRRINANSFRTSHYPYSNAHLDLADEFGVLVILEAPLVGLREHHFSNRDYLEKAKRVI
HHHEEECCCCEECCCCCCCCCEEEECCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHH
SEMIRQHRNRPSVVMYSVANEPNSITDEARVFLGELMNHVKSIDPTRPVIYTSFRHLDDK
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCH
ALGLGDAVALNIYFGWYSDTGDVETGVAKAVKLIEEVHSRYPDKPIIITEFGAEGVTGLH
HCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
HDPPVAWSEEYQELFLRRYIEELSKKPYVRGLHIWNYADFRTPQNPRRVILNTKGLYTRD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCEECC
RRPKLATRTVAELFSKLK
CCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTGVRPRIPLDGFWGFRLDPGNAGESNGWFKGFESSDHIYVPASWNEQNPDWDGYSGVA
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHH
WYLMDFYVPRELNGLTPWIIFEGSGYLSRVWVNGVFIGEHEGSFTLFKFKIPNLNYGGWN
HHHHHHHCCHHCCCCCCEEEEECCCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCE
RVVVKIDNTLKPDNIPPGEGLNATYFDFYHYGGIQRPVWVEFTHGCFIDDLIIATRHDGY
EEEEEECCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCE
LKVQPVVNCSRPFKLELSLLDKSGGVVYSRVVEGAFEDYVKGLEPWSIEHPVLYTLEARL
EEEEEEECCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
ITNNDVEDTVTERIGFRTFEVKAGGFYLNGESIFLKGFGRHEDYPIFGRALPGPVLIRDY
EECCCHHHHHHHHHCCEEEEEEECCEEECCCEEEEEECCCCCCCCEECCCCCCCEEEECC
YNMRRINANSFRTSHYPYSNAHLDLADEFGVLVILEAPLVGLREHHFSNRDYLEKAKRVI
HHHEEECCCCEECCCCCCCCCEEEECCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHH
SEMIRQHRNRPSVVMYSVANEPNSITDEARVFLGELMNHVKSIDPTRPVIYTSFRHLDDK
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCH
ALGLGDAVALNIYFGWYSDTGDVETGVAKAVKLIEEVHSRYPDKPIIITEFGAEGVTGLH
HCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
HDPPVAWSEEYQELFLRRYIEELSKKPYVRGLHIWNYADFRTPQNPRRVILNTKGLYTRD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCEECC
RRPKLATRTVAELFSKLK
CCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]