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The map label for this gene is rsmA [H]

Identifier: 159041898

GI number: 159041898

Start: 1410811

End: 1411632

Strand: Reverse

Name: rsmA [H]

Synonym: Cmaq_1334

Alternate gene names: 159041898

Gene position: 1411632-1410811 (Counterclockwise)

Preceding gene: 159041900

Following gene: 159041897

Centisome position: 67.95

GC content: 41.85

Gene sequence:

>822_bases
GTGGTGTCGCTTAATGACTTTTACGCAGTCGATAAGTGGACTCTAATTAAGTTAGCTAAGTCAGCCCTAGGGCTTGGAAT
TAGGGTTGGTGGCGATGTGCACTTCATGGTTGATCCAGTTTACCTTAACACCATTGCGCAATTAGCTAAGGATGAGAAGG
TTCTTGAGGTGGGGTTTGGTTTAAGTTACTTAACGCATTACTTAGCTAAGTATGCTCAACACGTGTTCGCATGTGATGTG
AATCCAATGATGATCAAGGCCATTAAGGCTATTGGGTTGAGTGAAGTTAACGCTGACTTATTCATATGTGATGCATTAAC
CTACAAGCCACCTATTGAATTAACCGTGGTTTCAAACATACCCTATAGCATTACATCAAGGTTACTGTTAAGATTACTAA
CCGATTACGGGGCTAGGAAACTAATATTAACGCTGCAGAGGGAGGTGGCCTTAAGGCTTGCAGCTAAGCCTGGCTCCACG
GATTACGGTAGGCTTTCTGTGATTACCCAATGCCTGAGTCTAGTTAAGGTAATTAAGCATGTGCCTCCATGGGCCTTTTG
GCCAAGGCCTAAGGTGTATTCAGCAATTGTTGAGTTGAAGCCCTTACCTAAACCATGCGTTGATGTTAGGGCTTTAGAAT
CCTTAACAAGTAAATTATTCACCCAGCCTAATAAGAAGGCTATTAAAGTTATTAAGCAGTTTTACGGTTTAAGAGAGGGG
GAAGCGCCTAGTTACTTACTTAATAAGAGGGTTAGGGAGTTAAGCGTTAATGAGGTTGCTGAACTGGTTAATGTTTTAAT
CAACATGGGGAAAATTACGTAA

Upstream 100 bases:

>100_bases
AGGATTCTTGACACCGGCATTAACCCACCCTATCCTAGGTATCCCGGATAATGAATCCACTAGTTTTAAAAGTCTCCATA
GGTTAAGCATAATCACCCCT

Downstream 100 bases:

>100_bases
TTATGTTCATGTAATATAAATTACGTAATTATGTTCATGTAATATATGCCGCATGATCGCATCTATATATTTAACATATG
CTTTTTCTGCATAATTCCTC

Product: ribosomal RNA adenine methylase transferase

Products: NA

Alternate protein names: 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MVSLNDFYAVDKWTLIKLAKSALGLGIRVGGDVHFMVDPVYLNTIAQLAKDEKVLEVGFGLSYLTHYLAKYAQHVFACDV
NPMMIKAIKAIGLSEVNADLFICDALTYKPPIELTVVSNIPYSITSRLLLRLLTDYGARKLILTLQREVALRLAAKPGST
DYGRLSVITQCLSLVKVIKHVPPWAFWPRPKVYSAIVELKPLPKPCVDVRALESLTSKLFTQPNKKAIKVIKQFYGLREG
EAPSYLLNKRVRELSVNEVAELVNVLINMGKIT

Sequences:

>Translated_273_residues
MVSLNDFYAVDKWTLIKLAKSALGLGIRVGGDVHFMVDPVYLNTIAQLAKDEKVLEVGFGLSYLTHYLAKYAQHVFACDV
NPMMIKAIKAIGLSEVNADLFICDALTYKPPIELTVVSNIPYSITSRLLLRLLTDYGARKLILTLQREVALRLAAKPGST
DYGRLSVITQCLSLVKVIKHVPPWAFWPRPKVYSAIVELKPLPKPCVDVRALESLTSKLFTQPNKKAIKVIKQFYGLREG
EAPSYLLNKRVRELSVNEVAELVNVLINMGKIT
>Mature_273_residues
MVSLNDFYAVDKWTLIKLAKSALGLGIRVGGDVHFMVDPVYLNTIAQLAKDEKVLEVGFGLSYLTHYLAKYAQHVFACDV
NPMMIKAIKAIGLSEVNADLFICDALTYKPPIELTVVSNIPYSITSRLLLRLLTDYGARKLILTLQREVALRLAAKPGST
DYGRLSVITQCLSLVKVIKHVPPWAFWPRPKVYSAIVELKPLPKPCVDVRALESLTSKLFTQPNKKAIKVIKQFYGLREG
EAPSYLLNKRVRELSVNEVAELVNVLINMGKIT

Specific function: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Homo sapiens, GI7657198, Length=214, Percent_Identity=35.981308411215, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI156415992, Length=137, Percent_Identity=32.1167883211679, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1786236, Length=191, Percent_Identity=32.4607329842932, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25146882, Length=211, Percent_Identity=33.175355450237, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324989, Length=201, Percent_Identity=32.3383084577114, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21358017, Length=201, Percent_Identity=33.8308457711443, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30486; Mature: 30486

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLNDFYAVDKWTLIKLAKSALGLGIRVGGDVHFMVDPVYLNTIAQLAKDEKVLEVGFG
CCCCCHHHCCCHHHHHHHHHHHHCCCEEECCEEEEEECHHHHHHHHHHHCCCHHHHHHCC
LSYLTHYLAKYAQHVFACDVNPMMIKAIKAIGLSEVNADLFICDALTYKPPIELTVVSNI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCCCEEEEECCCCCCCEEEEEECCC
PYSITSRLLLRLLTDYGARKLILTLQREVALRLAAKPGSTDYGRLSVITQCLSLVKVIKH
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VPPWAFWPRPKVYSAIVELKPLPKPCVDVRALESLTSKLFTQPNKKAIKVIKQFYGLREG
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
EAPSYLLNKRVRELSVNEVAELVNVLINMGKIT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVSLNDFYAVDKWTLIKLAKSALGLGIRVGGDVHFMVDPVYLNTIAQLAKDEKVLEVGFG
CCCCCHHHCCCHHHHHHHHHHHHCCCEEECCEEEEEECHHHHHHHHHHHCCCHHHHHHCC
LSYLTHYLAKYAQHVFACDVNPMMIKAIKAIGLSEVNADLFICDALTYKPPIELTVVSNI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCCCEEEEECCCCCCCEEEEEECCC
PYSITSRLLLRLLTDYGARKLILTLQREVALRLAAKPGSTDYGRLSVITQCLSLVKVIKH
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VPPWAFWPRPKVYSAIVELKPLPKPCVDVRALESLTSKLFTQPNKKAIKVIKQFYGLREG
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
EAPSYLLNKRVRELSVNEVAELVNVLINMGKIT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Dimethylation [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]