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The map label for this gene is argC

Identifier: 159041866

GI number: 159041866

Start: 1373744

End: 1374808

Strand: Reverse

Name: argC

Synonym: Cmaq_1301

Alternate gene names: 159041866

Gene position: 1374808-1373744 (Counterclockwise)

Preceding gene: 159041870

Following gene: 159041865

Centisome position: 66.17

GC content: 47.7

Gene sequence:

>1065_bases
ATACGTAGAGCCTGCATAATAGGTGCCAGTGGCGTTATAGGCGGTGAATTACTTAGGCTGCTGCTTGGTCATAATAATGT
TGAAGTCGTCTGCGCAACCTCAAGAAGATTCGCAGGTGAATTCATATACAGGGTGCACCCAAACCTCAGGGGGTTCATTA
ACCTGAAGTTCACTCAACCCAGTATTGATGCGGTACTTAAGAGTGAATCAGACGTGGTCTTCCTAGCCCTACCCCACGGT
GAATCAGTTAAATGGGTACCTAAACTGGTTGAAAGCGGCCTATTGGCAATAGACCTAAGCGCAGACTTTAGGTTAAAGAA
CCCTGATGACTACGTTAAGTGGTATCACTGGCCTCAACCACACCCATACCCTGATTTACTTAAGGCCGCCGCCTACGGTC
TACCTGAACTACATAGGGATGAGATTAAGGCTACTAAGGTTATTGCAGTGCCTGGATGCATGGCTACAGCCTCAATAGTT
TCACTGGCGCCTCTGGTTAAGGGGCATTTAATTAACAATGACTTCATAGTGGTTGACGCTAAGATAGCCAGCAGCGGCGC
TGGAGCTGAGGGGACTGTGCTTGATTACCATTGGCATAGGACTCATGTTGTTAGGCCCTATCAACCTGTTGGCCATAGGC
ACACAGCCGAGATAGAGCAGGAGTTAAGCCTATTAGCCGGGAGTCAGGTTAATGTCGCCTTCACTCCGCATGCGGTTGAC
ATGGTTAGGGGGATTTTCGTAACTGGGCATGCTAGGTTAAGCGGCAGTATTAGTGAACCAGACTTATGGAGGGCCTATAG
GGGAATGTACGGTAACGAGAGGTTCATACGCATAGTTAAGGATAAGGCGGGTTTAGCCCACTACCCCAGCGTTAAGTATG
TTGTGGGGACGAATATGGTTGATGTTGGGTTTGAACTGGATCAAAGACTCAACCGTGTCGTGGTCTTCTCAGCCATAGAT
AACTTAATTAGAGGAGCAGCTGGGCAAGCTATTCAATCATTCAACATTAATCAAGGATTCCCTGAAGACGAGGGGCTTAG
GTTCATTACACCATACCCAGTTTAG

Upstream 100 bases:

>100_bases
GCGGGTGTTGACTCATTTTAATCAATTTAGCTTAAGATGGTCGTTAAGTTTATAAAGACTGAACCTATATAGGCTTCGGT
GAGTTTGTATTGAAGGGACG

Downstream 100 bases:

>100_bases
GTGATTAATAAATGATACTTGTTAAACTTGGTGGTTCAGTAATATGCGGTGGAGGCTTGGATAACGTTACTAATGATGTT
GAACCAGGCACCGTGCTTAT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRRACIIGASGVIGGELLRLLLGHNNVEVVCATSRRFAGEFIYRVHPNLRGFINLKFTQPSIDAVLKSESDVVFLALPHG
ESVKWVPKLVESGLLAIDLSADFRLKNPDDYVKWYHWPQPHPYPDLLKAAAYGLPELHRDEIKATKVIAVPGCMATASIV
SLAPLVKGHLINNDFIVVDAKIASSGAGAEGTVLDYHWHRTHVVRPYQPVGHRHTAEIEQELSLLAGSQVNVAFTPHAVD
MVRGIFVTGHARLSGSISEPDLWRAYRGMYGNERFIRIVKDKAGLAHYPSVKYVVGTNMVDVGFELDQRLNRVVVFSAID
NLIRGAAGQAIQSFNINQGFPEDEGLRFITPYPV

Sequences:

>Translated_354_residues
MRRACIIGASGVIGGELLRLLLGHNNVEVVCATSRRFAGEFIYRVHPNLRGFINLKFTQPSIDAVLKSESDVVFLALPHG
ESVKWVPKLVESGLLAIDLSADFRLKNPDDYVKWYHWPQPHPYPDLLKAAAYGLPELHRDEIKATKVIAVPGCMATASIV
SLAPLVKGHLINNDFIVVDAKIASSGAGAEGTVLDYHWHRTHVVRPYQPVGHRHTAEIEQELSLLAGSQVNVAFTPHAVD
MVRGIFVTGHARLSGSISEPDLWRAYRGMYGNERFIRIVKDKAGLAHYPSVKYVVGTNMVDVGFELDQRLNRVVVFSAID
NLIRGAAGQAIQSFNINQGFPEDEGLRFITPYPV
>Mature_354_residues
MRRACIIGASGVIGGELLRLLLGHNNVEVVCATSRRFAGEFIYRVHPNLRGFINLKFTQPSIDAVLKSESDVVFLALPHG
ESVKWVPKLVESGLLAIDLSADFRLKNPDDYVKWYHWPQPHPYPDLLKAAAYGLPELHRDEIKATKVIAVPGCMATASIV
SLAPLVKGHLINNDFIVVDAKIASSGAGAEGTVLDYHWHRTHVVRPYQPVGHRHTAEIEQELSLLAGSQVNVAFTPHAVD
MVRGIFVTGHARLSGSISEPDLWRAYRGMYGNERFIRIVKDKAGLAHYPSVKYVVGTNMVDVGFELDQRLNRVVVFSAID
NLIRGAAGQAIQSFNINQGFPEDEGLRFITPYPV

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=350, Percent_Identity=32.8571428571429, Blast_Score=174, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320913, Length=351, Percent_Identity=31.3390313390313, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_CALMQ (A8M8Q9)

Other databases:

- EMBL:   CP000852
- RefSeq:   YP_001541118.1
- ProteinModelPortal:   A8M8Q9
- SMR:   A8M8Q9
- GeneID:   5708908
- GenomeReviews:   CP000852_GR
- KEGG:   cma:Cmaq_1301
- HOGENOM:   HBG294213
- OMA:   GCMATAS
- ProtClustDB:   PRK00436
- BioCyc:   CMAQ397948:CMAQ_1301-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 39115; Mature: 39115

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 153-153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRACIIGASGVIGGELLRLLLGHNNVEVVCATSRRFAGEFIYRVHPNLRGFINLKFTQP
CCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEEEECC
SIDAVLKSESDVVFLALPHGESVKWVPKLVESGLLAIDLSADFRLKNPDDYVKWYHWPQP
CHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCEEEEEECCCEEECCCCCCEEEEECCCC
HPYPDLLKAAAYGLPELHRDEIKATKVIAVPGCMATASIVSLAPLVKGHLINNDFIVVDA
CCCHHHHHHHHCCCCHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHCEEECCCEEEEEE
KIASSGAGAEGTVLDYHWHRTHVVRPYQPVGHRHTAEIEQELSLLAGSQVNVAFTPHAVD
EEECCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHH
MVRGIFVTGHARLSGSISEPDLWRAYRGMYGNERFIRIVKDKAGLAHYPSVKYVVGTNMV
HHHEEEEEECEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECCEE
DVGFELDQRLNRVVVFSAIDNLIRGAAGQAIQSFNINQGFPEDEGLRFITPYPV
EECCHHHHHHCEEEEHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MRRACIIGASGVIGGELLRLLLGHNNVEVVCATSRRFAGEFIYRVHPNLRGFINLKFTQP
CCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEEEECC
SIDAVLKSESDVVFLALPHGESVKWVPKLVESGLLAIDLSADFRLKNPDDYVKWYHWPQP
CHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCEEEEEECCCEEECCCCCCEEEEECCCC
HPYPDLLKAAAYGLPELHRDEIKATKVIAVPGCMATASIVSLAPLVKGHLINNDFIVVDA
CCCHHHHHHHHCCCCHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHCEEECCCEEEEEE
KIASSGAGAEGTVLDYHWHRTHVVRPYQPVGHRHTAEIEQELSLLAGSQVNVAFTPHAVD
EEECCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHH
MVRGIFVTGHARLSGSISEPDLWRAYRGMYGNERFIRIVKDKAGLAHYPSVKYVVGTNMV
HHHEEEEEECEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECCEE
DVGFELDQRLNRVVVFSAIDNLIRGAAGQAIQSFNINQGFPEDEGLRFITPYPV
EECCHHHHHHCEEEEHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA