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The map label for this gene is trpA [H]

Identifier: 159041614

GI number: 159041614

Start: 1097700

End: 1098428

Strand: Reverse

Name: trpA [H]

Synonym: Cmaq_1047

Alternate gene names: 159041614

Gene position: 1098428-1097700 (Counterclockwise)

Preceding gene: 159041616

Following gene: 159041613

Centisome position: 52.87

GC content: 43.48

Gene sequence:

>729_bases
ATGGGTATAAGTAGGCCCGCCTTGGGCCTATATTTAACGGCAACGTACCCAAGTACTAAACGCTTCCTAGAGACCCTTGA
TAAGATAAGTGGCCTCGTGGACTTCCTGGAAATAGGCATACCGACACGTAATCCTAAGTATGATGGGCCGGTTATAAGGA
TGGCTCACCAGGGTGCTGAGTTAATGGGTCTTAATGCAGTTAAGGTTACTGATGACTACAGTAAGTATGGTAAAGTACCT
GTGCTAATGGGTTATATTAGTGATTACGTGAACTCACTCAATGATGTGGCTAAGACAGCTAGTGATGTTGGGGCCGCCAC
TGTATTATTCCCTGACCTAATATTCGATTACCCTGAGTTAATAGGTAGGTACATTGAGGTTATGAGGAGTAATGGATTAG
CCCCCAGCTTCTTCATATCAAGTAAAACACCCTATAGGTTAATTAGGAGCCTAAGTGAACAGGAACCATTATTCATATAC
CTAGGCCTATACGCGGCCACTGGTATTAAGTTGCCTATTTACATTGAGCAGAATGTAGTAACTATTAGGGGTGTTTTAGG
TGATGCATTCCTTATCGTGGGTTTCGCAGTTAATAGCCCTGATATGGTTAGGTCATTGATTAAGGCTGGGGCTGATGGGG
TTGTTGTTGGTTCAGCCTTCATTCAAAGAATGAGTGACCTTAATGATGCGTTAAGCTTCCTTAAGTGGCTTAGGGGTGGT
TTACCGTGA

Upstream 100 bases:

>100_bases
AAAACATTTCATGTCAAGTAACGTTCACTTTAGCGTTTATAGCGCAGTAATGCTTAAAAATAGTTAACCGAAATACACCT
ATGAGGGACGGTAAGCTCCA

Downstream 100 bases:

>100_bases
GTGGTGTTCCAACTCATTGGTATAACATAGCCGTTGACCTACCTAAACCACTACCACCACCCATGGATCCCTATGAGGGT
GAGTCCAGGATAGCTTTACT

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MGISRPALGLYLTATYPSTKRFLETLDKISGLVDFLEIGIPTRNPKYDGPVIRMAHQGAELMGLNAVKVTDDYSKYGKVP
VLMGYISDYVNSLNDVAKTASDVGAATVLFPDLIFDYPELIGRYIEVMRSNGLAPSFFISSKTPYRLIRSLSEQEPLFIY
LGLYAATGIKLPIYIEQNVVTIRGVLGDAFLIVGFAVNSPDMVRSLIKAGADGVVVGSAFIQRMSDLNDALSFLKWLRGG
LP

Sequences:

>Translated_242_residues
MGISRPALGLYLTATYPSTKRFLETLDKISGLVDFLEIGIPTRNPKYDGPVIRMAHQGAELMGLNAVKVTDDYSKYGKVP
VLMGYISDYVNSLNDVAKTASDVGAATVLFPDLIFDYPELIGRYIEVMRSNGLAPSFFISSKTPYRLIRSLSEQEPLFIY
LGLYAATGIKLPIYIEQNVVTIRGVLGDAFLIVGFAVNSPDMVRSLIKAGADGVVVGSAFIQRMSDLNDALSFLKWLRGG
LP
>Mature_241_residues
GISRPALGLYLTATYPSTKRFLETLDKISGLVDFLEIGIPTRNPKYDGPVIRMAHQGAELMGLNAVKVTDDYSKYGKVPV
LMGYISDYVNSLNDVAKTASDVGAATVLFPDLIFDYPELIGRYIEVMRSNGLAPSFFISSKTPYRLIRSLSEQEPLFIYL
GLYAATGIKLPIYIEQNVVTIRGVLGDAFLIVGFAVNSPDMVRSLIKAGADGVVVGSAFIQRMSDLNDALSFLKWLRGGL
P

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 26457; Mature: 26326

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISRPALGLYLTATYPSTKRFLETLDKISGLVDFLEIGIPTRNPKYDGPVIRMAHQGAE
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCH
LMGLNAVKVTDDYSKYGKVPVLMGYISDYVNSLNDVAKTASDVGAATVLFPDLIFDYPEL
HHCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
IGRYIEVMRSNGLAPSFFISSKTPYRLIRSLSEQEPLFIYLGLYAATGIKLPIYIEQNVV
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEEHHHHCCCEEEEEEECCEE
TIRGVLGDAFLIVGFAVNSPDMVRSLIKAGADGVVVGSAFIQRMSDLNDALSFLKWLRGG
EEHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
LP
CC
>Mature Secondary Structure 
GISRPALGLYLTATYPSTKRFLETLDKISGLVDFLEIGIPTRNPKYDGPVIRMAHQGAE
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCH
LMGLNAVKVTDDYSKYGKVPVLMGYISDYVNSLNDVAKTASDVGAATVLFPDLIFDYPEL
HHCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
IGRYIEVMRSNGLAPSFFISSKTPYRLIRSLSEQEPLFIYLGLYAATGIKLPIYIEQNVV
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEEHHHHCCCEEEEEEECCEE
TIRGVLGDAFLIVGFAVNSPDMVRSLIKAGADGVVVGSAFIQRMSDLNDALSFLKWLRGG
EEHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
LP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]