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The map label for this gene is trpD

Identifier: 159041612

GI number: 159041612

Start: 1095437

End: 1096456

Strand: Reverse

Name: trpD

Synonym: Cmaq_1045

Alternate gene names: 159041612

Gene position: 1096456-1095437 (Counterclockwise)

Preceding gene: 159041613

Following gene: 159041611

Centisome position: 52.78

GC content: 48.33

Gene sequence:

>1020_bases
ATGAGGCCACTCCTAGAGAAGATAGCTAGGGGTCTTGAGTTGAGTCTTGAGGAGGCCTATAACGCCGCCTTAGCCATATT
AAAGATGGAGGCAGGTGAGGCTGAGACTGCTGCGTTACTCATGGGGCTTAGGGTGAGGGGTGAGCGTGCCTTTGAGGTTG
CAGGCTTCGCTAAGGCGCTTAGGGAAACATGCCTAAGAATACCGGTTAATGACCCATACGTAATAGATACAGCTGGCACT
GGGGGTGATGGGTTAAGGACAATGAACGTATCCACTATTTCAGCATTACTGGCAGCCTACCTGGGGGTTAAGGTGCTTAA
GCACGGTAATAGGAGTGTCTCATCATCATCAGGCAGCGCAGACTTCCTGGAGGCCCTCGGCTTCAACATAAGTGTGAAAC
CTGAAACTGCATTACTAATGCTGAATAACCATAGGTTCTCATTCGCCTTCGCGCCAATGTACCACCCAGCCATGAAGAAT
GTTATGCCTGTTAGGAGGAGGCTCGGTATAAGAACTATATTTAACCTAGTGGGTCCATTGGCTAATCCAGGCCTTGTGAG
GAGGCAGGTGCTTGGTGTGGCTGAGGCTGGAATAATGGGGGTTATGGCTGAGGCAGCTGGTTTAATAGGTTATGACCACC
TCCTGTTAGTTCACGGTGAACCAGGTATTGATGAGGTTTCAGTATTCGGGAGAACAATGATATATGAGGTTAAGGGTAAT
TCCATTGATAAATACGTAATTGAGCCCCCTGAACTTGGTTTACGCATACATGAGTTAAGGGATGTAGTGGTCTCTAACCC
AATGGAGAGCATTGAGAAGGCTAAGAGGGGTTTAATGGGTGTTGATGAAGCTGCCTTAGACTTCATAGCCGCCAACACAG
CAATGGCGCTCTACGTCGCTGGTAAGGTTAAGGATCCTAGGGATGGTGTTGAGGCCGTTAAGCAGATTGCAGGTAATTCA
AACGACTTCTGGAGCTACGTTAATAATGTCGCAGCAGTGAGTAGGCGTGACTCTGCTTAA

Upstream 100 bases:

>100_bases
TTGATGAAGCCAGGAGAATGCCTAAGGGCAGTGTAATATTGTTTAACCTATCTGGGCATGGTTTACTGGATCCTGACGCC
TACGAGAAGGTGAACGCATC

Downstream 100 bases:

>100_bases
GGTTTGCGGATTAACGAGGAGGATTGACGTAGAGTTCATTGATAAGCACGCCGATTACGCAGGCTTCATAATTCACTCAG
ATGTTAAGACCCAGAGGCTA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRPLLEKIARGLELSLEEAYNAALAILKMEAGEAETAALLMGLRVRGERAFEVAGFAKALRETCLRIPVNDPYVIDTAGT
GGDGLRTMNVSTISALLAAYLGVKVLKHGNRSVSSSSGSADFLEALGFNISVKPETALLMLNNHRFSFAFAPMYHPAMKN
VMPVRRRLGIRTIFNLVGPLANPGLVRRQVLGVAEAGIMGVMAEAAGLIGYDHLLLVHGEPGIDEVSVFGRTMIYEVKGN
SIDKYVIEPPELGLRIHELRDVVVSNPMESIEKAKRGLMGVDEAALDFIAANTAMALYVAGKVKDPRDGVEAVKQIAGNS
NDFWSYVNNVAAVSRRDSA

Sequences:

>Translated_339_residues
MRPLLEKIARGLELSLEEAYNAALAILKMEAGEAETAALLMGLRVRGERAFEVAGFAKALRETCLRIPVNDPYVIDTAGT
GGDGLRTMNVSTISALLAAYLGVKVLKHGNRSVSSSSGSADFLEALGFNISVKPETALLMLNNHRFSFAFAPMYHPAMKN
VMPVRRRLGIRTIFNLVGPLANPGLVRRQVLGVAEAGIMGVMAEAAGLIGYDHLLLVHGEPGIDEVSVFGRTMIYEVKGN
SIDKYVIEPPELGLRIHELRDVVVSNPMESIEKAKRGLMGVDEAALDFIAANTAMALYVAGKVKDPRDGVEAVKQIAGNS
NDFWSYVNNVAAVSRRDSA
>Mature_339_residues
MRPLLEKIARGLELSLEEAYNAALAILKMEAGEAETAALLMGLRVRGERAFEVAGFAKALRETCLRIPVNDPYVIDTAGT
GGDGLRTMNVSTISALLAAYLGVKVLKHGNRSVSSSSGSADFLEALGFNISVKPETALLMLNNHRFSFAFAPMYHPAMKN
VMPVRRRLGIRTIFNLVGPLANPGLVRRQVLGVAEAGIMGVMAEAAGLIGYDHLLLVHGEPGIDEVSVFGRTMIYEVKGN
SIDKYVIEPPELGLRIHELRDVVVSNPMESIEKAKRGLMGVDEAALDFIAANTAMALYVAGKVKDPRDGVEAVKQIAGNS
NDFWSYVNNVAAVSRRDSA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=280, Percent_Identity=36.7857142857143, Blast_Score=167, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320561, Length=361, Percent_Identity=29.9168975069252, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_CALMQ (A8MDL8)

Other databases:

- EMBL:   CP000852
- RefSeq:   YP_001540864.1
- ProteinModelPortal:   A8MDL8
- SMR:   A8MDL8
- GeneID:   5710181
- GenomeReviews:   CP000852_GR
- KEGG:   cma:Cmaq_1045
- HOGENOM:   HBG559996
- OMA:   ERTHEES
- ProtClustDB:   PRK00188
- BioCyc:   CMAQ397948:CMAQ_1045-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36523; Mature: 36523

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLLEKIARGLELSLEEAYNAALAILKMEAGEAETAALLMGLRVRGERAFEVAGFAKAL
CCHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
RETCLRIPVNDPYVIDTAGTGGDGLRTMNVSTISALLAAYLGVKVLKHGNRSVSSSSGSA
HHHHHCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DFLEALGFNISVKPETALLMLNNHRFSFAFAPMYHPAMKNVMPVRRRLGIRTIFNLVGPL
HHHHHCCCCEEECCCEEEEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANPGLVRRQVLGVAEAGIMGVMAEAAGLIGYDHLLLVHGEPGIDEVSVFGRTMIYEVKGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCEEEEEECCC
SIDKYVIEPPELGLRIHELRDVVVSNPMESIEKAKRGLMGVDEAALDFIAANTAMALYVA
CCCCEEECCHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEE
GKVKDPRDGVEAVKQIAGNSNDFWSYVNNVAAVSRRDSA
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRPLLEKIARGLELSLEEAYNAALAILKMEAGEAETAALLMGLRVRGERAFEVAGFAKAL
CCHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
RETCLRIPVNDPYVIDTAGTGGDGLRTMNVSTISALLAAYLGVKVLKHGNRSVSSSSGSA
HHHHHCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DFLEALGFNISVKPETALLMLNNHRFSFAFAPMYHPAMKNVMPVRRRLGIRTIFNLVGPL
HHHHHCCCCEEECCCEEEEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANPGLVRRQVLGVAEAGIMGVMAEAAGLIGYDHLLLVHGEPGIDEVSVFGRTMIYEVKGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCEEEEEECCC
SIDKYVIEPPELGLRIHELRDVVVSNPMESIEKAKRGLMGVDEAALDFIAANTAMALYVA
CCCCEEECCHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEE
GKVKDPRDGVEAVKQIAGNSNDFWSYVNNVAAVSRRDSA
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA