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The map label for this gene is hmeD [H]

Identifier: 159041424

GI number: 159041424

Start: 895730

End: 897211

Strand: Reverse

Name: hmeD [H]

Synonym: Cmaq_0851

Alternate gene names: 159041424

Gene position: 897211-895730 (Counterclockwise)

Preceding gene: 159041425

Following gene: 159041422

Centisome position: 43.19

GC content: 44.6

Gene sequence:

>1482_bases
ATGGTTAATGTTAAAGTTAAGTATAAGGGTGAGGACAAGGATATACTGGAGACTAGCCCACGCTACAGTGAGTGGGTTAA
GGAGTTCAGTAAAGGTAGTGGTCACTTGAAGGCTAGGGTTGAGGCTGATGAAGGTACATTAGGTACAATAGAGATGAATA
AATTAACTAAGGTTAAGCCTAATTTAAGTGATAGGAAACTCTACTTCATTAATAGGATAGGGGAATTAGCAAGGAGTAGT
AGGGCTTTTAGAAACTACATGGAGTCATGCACCCACTGTGGCTTCTGTATAGATAAATGCCAAATGTGGCTGGCCACAAG
GGACCCCAATAATAGCCCCGTTGGTAGGGCTGACTTAATTAGAAACATATACAGGAGGATGCGTAAATTAACCTTTGGCC
TAGTGGATAAGTTGAGTGATGAGGAGGAATTAAAGCGGTTAATGGATAGTGTTGACTTGGATAAGATATGGACCTACTAC
TACCAGTGCACTGAATGCAGGAGATGCGCGTACTTCTGTCCCTTTGGCATTGATCAAGCTGAGATAACTAGGTCTATTAG
GCAAATATTCGTTGAAATGGGTATGATGCCCCCCTTCATAGCTAAGACAATGGAGTGTGTTTATAAGACTGGCAATAACA
TGTGTATTACTAAGGATGCAGCACTTAATGTAATAGACTTCACTGTTAGTGAGATAAGTGAGCAGACTGGTAGGAAAATG
GAGGGGGTGGTGGATAAGGATAAGGCTGATGTACTCTACATACCATCATCCACCGACTTCTTCACTAACATTGGTACGTT
AAAGGGGGCTATAGCAGTAATGACTGAGCTTGGTCTTAATTGGACAATGGACTCCCAGGCCCTTGAGGTGGGTAACTTCG
GGCTCTTTGAGGATGAATACCACTTAAGGAGGTTTGGGGATAATATTGTTAATGCGGCCTTGAGGAGGAAGGCTAAGGTA
GTTGTATTCGGGGAATGTGGACATGGGTGGAGAGCCTTTAAGAACTACGTAGTCCCCAGGCTTGCTGAACATGGCATTAA
TGGAATCTCCATAACGCAGTTAACGGCATGGGCTCTTAAGAAGGGTAAATTGAAGATAAGCAATAAGGTTGATGCAGTGG
TGACTTACCATGACCCATGTAACCTAGCCAGGGCAGGGGACTTAATTGAGGAACCCAGGGAGATACTTAAGTCAACTGTT
AAGGAATTTAGGGAGAGGGAGCATAATAGGGAGAGAACCCTATGCTGTGGGGCTGGTGGCGGGTTACTGCTTGATGAATT
AATGCCCCTAAGGGTTTGGGCAGGTTGGCCATCGGTGTACGATGCCTACCGCACTGGGGCACAGTACATGGTTGCGCCCT
GTAGTATTGATAAGGCCCAGTTCCCTCTAGTGATAGAGTATCATAAGGTTCCCTTGAAGTTCAGGGGTGTGTCTGATTTC
GTCTACGCCGCCCTATATGGTATTGACATAGATTCCGTTTAA

Upstream 100 bases:

>100_bases
ATTCACCCATTCTCAATGCCCGTTAACCCAGCCCTTTATGGTAAGTTTGAAGACGTTAATGAAGTTGAGGAGAGGGTTAC
GGGAATCTGGGGTGGTAGTC

Downstream 100 bases:

>100_bases
GAAGTTAGGCATTGATTAATGTTACTCTTAATGAAGTCCTCAATCACCTTAACATGCTGAGACCTGGGGGTATGCCCCAT
ACCCTCTATTGTTAATTCAA

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: Hme subunit D [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MVNVKVKYKGEDKDILETSPRYSEWVKEFSKGSGHLKARVEADEGTLGTIEMNKLTKVKPNLSDRKLYFINRIGELARSS
RAFRNYMESCTHCGFCIDKCQMWLATRDPNNSPVGRADLIRNIYRRMRKLTFGLVDKLSDEEELKRLMDSVDLDKIWTYY
YQCTECRRCAYFCPFGIDQAEITRSIRQIFVEMGMMPPFIAKTMECVYKTGNNMCITKDAALNVIDFTVSEISEQTGRKM
EGVVDKDKADVLYIPSSTDFFTNIGTLKGAIAVMTELGLNWTMDSQALEVGNFGLFEDEYHLRRFGDNIVNAALRRKAKV
VVFGECGHGWRAFKNYVVPRLAEHGINGISITQLTAWALKKGKLKISNKVDAVVTYHDPCNLARAGDLIEEPREILKSTV
KEFREREHNRERTLCCGAGGGLLLDELMPLRVWAGWPSVYDAYRTGAQYMVAPCSIDKAQFPLVIEYHKVPLKFRGVSDF
VYAALYGIDIDSV

Sequences:

>Translated_493_residues
MVNVKVKYKGEDKDILETSPRYSEWVKEFSKGSGHLKARVEADEGTLGTIEMNKLTKVKPNLSDRKLYFINRIGELARSS
RAFRNYMESCTHCGFCIDKCQMWLATRDPNNSPVGRADLIRNIYRRMRKLTFGLVDKLSDEEELKRLMDSVDLDKIWTYY
YQCTECRRCAYFCPFGIDQAEITRSIRQIFVEMGMMPPFIAKTMECVYKTGNNMCITKDAALNVIDFTVSEISEQTGRKM
EGVVDKDKADVLYIPSSTDFFTNIGTLKGAIAVMTELGLNWTMDSQALEVGNFGLFEDEYHLRRFGDNIVNAALRRKAKV
VVFGECGHGWRAFKNYVVPRLAEHGINGISITQLTAWALKKGKLKISNKVDAVVTYHDPCNLARAGDLIEEPREILKSTV
KEFREREHNRERTLCCGAGGGLLLDELMPLRVWAGWPSVYDAYRTGAQYMVAPCSIDKAQFPLVIEYHKVPLKFRGVSDF
VYAALYGIDIDSV
>Mature_493_residues
MVNVKVKYKGEDKDILETSPRYSEWVKEFSKGSGHLKARVEADEGTLGTIEMNKLTKVKPNLSDRKLYFINRIGELARSS
RAFRNYMESCTHCGFCIDKCQMWLATRDPNNSPVGRADLIRNIYRRMRKLTFGLVDKLSDEEELKRLMDSVDLDKIWTYY
YQCTECRRCAYFCPFGIDQAEITRSIRQIFVEMGMMPPFIAKTMECVYKTGNNMCITKDAALNVIDFTVSEISEQTGRKM
EGVVDKDKADVLYIPSSTDFFTNIGTLKGAIAVMTELGLNWTMDSQALEVGNFGLFEDEYHLRRFGDNIVNAALRRKAKV
VVFGECGHGWRAFKNYVVPRLAEHGINGISITQLTAWALKKGKLKISNKVDAVVTYHDPCNLARAGDLIEEPREILKSTV
KEFREREHNRERTLCCGAGGGLLLDELMPLRVWAGWPSVYDAYRTGAQYMVAPCSIDKAQFPLVIEYHKVPLKFRGVSDF
VYAALYGIDIDSV

Specific function: Has menaquinol-oxidizing activity. HmeC and hmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 56142; Mature: 56142

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVKVKYKGEDKDILETSPRYSEWVKEFSKGSGHLKARVEADEGTLGTIEMNKLTKVKP
CEEEEEEECCCCCHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCEECCC
NLSDRKLYFINRIGELARSSRAFRNYMESCTHCGFCIDKCQMWLATRDPNNSPVGRADLI
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHH
RNIYRRMRKLTFGLVDKLSDEEELKRLMDSVDLDKIWTYYYQCTECRRCAYFCPFGIDQA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCHH
EITRSIRQIFVEMGMMPPFIAKTMECVYKTGNNMCITKDAALNVIDFTVSEISEQTGRKM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCHH
EGVVDKDKADVLYIPSSTDFFTNIGTLKGAIAVMTELGLNWTMDSQALEVGNFGLFEDEY
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECHHHHCCCCCCCCCCHH
HLRRFGDNIVNAALRRKAKVVVFGECGHGWRAFKNYVVPRLAEHGINGISITQLTAWALK
HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
KGKLKISNKVDAVVTYHDPCNLARAGDLIEEPREILKSTVKEFREREHNRERTLCCGAGG
CCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
GLLLDELMPLRVWAGWPSVYDAYRTGAQYMVAPCSIDKAQFPLVIEYHKVPLKFRGVSDF
CHHHHHHHHHHEECCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCEEECCHHHH
VYAALYGIDIDSV
HHHHHHCCCCCCC
>Mature Secondary Structure
MVNVKVKYKGEDKDILETSPRYSEWVKEFSKGSGHLKARVEADEGTLGTIEMNKLTKVKP
CEEEEEEECCCCCHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCEECCC
NLSDRKLYFINRIGELARSSRAFRNYMESCTHCGFCIDKCQMWLATRDPNNSPVGRADLI
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHH
RNIYRRMRKLTFGLVDKLSDEEELKRLMDSVDLDKIWTYYYQCTECRRCAYFCPFGIDQA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCHH
EITRSIRQIFVEMGMMPPFIAKTMECVYKTGNNMCITKDAALNVIDFTVSEISEQTGRKM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCHH
EGVVDKDKADVLYIPSSTDFFTNIGTLKGAIAVMTELGLNWTMDSQALEVGNFGLFEDEY
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECHHHHCCCCCCCCCCHH
HLRRFGDNIVNAALRRKAKVVVFGECGHGWRAFKNYVVPRLAEHGINGISITQLTAWALK
HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
KGKLKISNKVDAVVTYHDPCNLARAGDLIEEPREILKSTVKEFREREHNRERTLCCGAGG
CCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
GLLLDELMPLRVWAGWPSVYDAYRTGAQYMVAPCSIDKAQFPLVIEYHKVPLKFRGVSDF
CHHHHHHHHHHEECCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCEEECCHHHH
VYAALYGIDIDSV
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]