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The map label for this gene is fucA [H]

Identifier: 159041285

GI number: 159041285

Start: 746623

End: 747291

Strand: Reverse

Name: fucA [H]

Synonym: Cmaq_0711

Alternate gene names: 159041285

Gene position: 747291-746623 (Counterclockwise)

Preceding gene: 159041287

Following gene: 159041284

Centisome position: 35.97

GC content: 47.53

Gene sequence:

>669_bases
ATGTCAACAGGGGAAGAGGGACCTAGCCTCATTAGTGAGGATGAGATTAAGAATGAGATTACGCGTGTAATGAAGGCACT
GTATGAGAGAGGATTAGTGTCTGCGCTTGGGGGTAATGTTAGTGCCAGGGTACCTGGAGCCAGTGAATTTTGGATAACAC
CCAGTGGTGTCTTTAAGGGTGCTGTTAATGTTGATGACTTAGTTAAGGTTGATTTAGATGGTAATGTGGTTGAGGGCGTG
CTTAGGCCATCAACAGAGACTCCATTTCACGCAGCCATATATAAAGTTAGGCCGGATGTTAACGCAGTGATTCATGCACA
TAACCCAGTAACATTAGGGTTAGCGTTGGCTGGTGTTAACTTGAAGCCAATATCCGTTGAGGCTATTATGACCCTGAGGA
AGGTTGAGGTCGTTCCCTTTGCCTTCCCTGGGACTGACCAATTAGCTAAGCTTGTTGCTGATGCTGCGCTTAAGGGTGCG
CGTGCAATAATACTGATGAATCATGGGGTAGTGGGTATGGGGGCTAATTTACTTGAGGCTGAGGCTGTGGTGGAGACCCT
TGAGGAGGTTGCCACTGCGCAGTTTGTGGCCATGGTGTTAGGTAAGGAACCACCAGTTATACCTGAGAAGGATGTGGAGC
TCTACATGAAGTTGTACTTCCAGGGTTAG

Upstream 100 bases:

>100_bases
CATGATGATTTAATGTTCATTGAGTCTTCATGCATACCTAACATGTTAGGATAAACATAATGGTAAAATGCTTATATACA
TCTGATTAAATATTCACTGC

Downstream 100 bases:

>100_bases
GTGGACTGCATGAGTGAATGGTATGGGTACATAGGGAAGATACTTGAGGTTGATTTAAGCAGTGGTAAAACTAGGGTTAG
GGAATTGAAGGAAGAGGATG

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSTGEEGPSLISEDEIKNEITRVMKALYERGLVSALGGNVSARVPGASEFWITPSGVFKGAVNVDDLVKVDLDGNVVEGV
LRPSTETPFHAAIYKVRPDVNAVIHAHNPVTLGLALAGVNLKPISVEAIMTLRKVEVVPFAFPGTDQLAKLVADAALKGA
RAIILMNHGVVGMGANLLEAEAVVETLEEVATAQFVAMVLGKEPPVIPEKDVELYMKLYFQG

Sequences:

>Translated_222_residues
MSTGEEGPSLISEDEIKNEITRVMKALYERGLVSALGGNVSARVPGASEFWITPSGVFKGAVNVDDLVKVDLDGNVVEGV
LRPSTETPFHAAIYKVRPDVNAVIHAHNPVTLGLALAGVNLKPISVEAIMTLRKVEVVPFAFPGTDQLAKLVADAALKGA
RAIILMNHGVVGMGANLLEAEAVVETLEEVATAQFVAMVLGKEPPVIPEKDVELYMKLYFQG
>Mature_221_residues
STGEEGPSLISEDEIKNEITRVMKALYERGLVSALGGNVSARVPGASEFWITPSGVFKGAVNVDDLVKVDLDGNVVEGVL
RPSTETPFHAAIYKVRPDVNAVIHAHNPVTLGLALAGVNLKPISVEAIMTLRKVEVVPFAFPGTDQLAKLVADAALKGAR
AIILMNHGVVGMGANLLEAEAVVETLEEVATAQFVAMVLGKEPPVIPEKDVELYMKLYFQG

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. The substrate preference order is glyceraldehyde > DL- lactaldehyde, glycolaldehyde > acrolein > formaldehyde, methylglyoxal > acet

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Homo sapiens, GI9257190, Length=191, Percent_Identity=29.8429319371728, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI89276787, Length=191, Percent_Identity=29.8429319371728, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI297307160, Length=191, Percent_Identity=29.8429319371728, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI29826325, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI29826323, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI29826321, Length=166, Percent_Identity=30.7228915662651, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI29826319, Length=166, Percent_Identity=30.7228915662651, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789094, Length=197, Percent_Identity=32.48730964467, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789164, Length=215, Percent_Identity=26.9767441860465, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786247, Length=232, Percent_Identity=26.2931034482759, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790008, Length=222, Percent_Identity=25.6756756756757, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790642, Length=106, Percent_Identity=33.9622641509434, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23612; Mature: 23480

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGEEGPSLISEDEIKNEITRVMKALYERGLVSALGGNVSARVPGASEFWITPSGVFKG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEECCCCCEEEECCHHHHCC
AVNVDDLVKVDLDGNVVEGVLRPSTETPFHAAIYKVRPDVNAVIHAHNPVTLGLALAGVN
CCCCCCEEEECCCCHHHHHEECCCCCCCCEEEEEEECCCCEEEEECCCCEEEEEEEECCC
LKPISVEAIMTLRKVEVVPFAFPGTDQLAKLVADAALKGARAIILMNHGVVGMGANLLEA
CCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCEEECCCHHHHH
EAVVETLEEVATAQFVAMVLGKEPPVIPEKDVELYMKLYFQG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEECC
>Mature Secondary Structure 
STGEEGPSLISEDEIKNEITRVMKALYERGLVSALGGNVSARVPGASEFWITPSGVFKG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEECCCCCEEEECCHHHHCC
AVNVDDLVKVDLDGNVVEGVLRPSTETPFHAAIYKVRPDVNAVIHAHNPVTLGLALAGVN
CCCCCCEEEECCCCHHHHHEECCCCCCCCEEEEEEECCCCEEEEECCCCEEEEEEEECCC
LKPISVEAIMTLRKVEVVPFAFPGTDQLAKLVADAALKGARAIILMNHGVVGMGANLLEA
CCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCEEECCCHHHHH
EAVVETLEEVATAQFVAMVLGKEPPVIPEKDVELYMKLYFQG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]