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The map label for this gene is idsA [H]

Identifier: 159041215

GI number: 159041215

Start: 672166

End: 673188

Strand: Reverse

Name: idsA [H]

Synonym: Cmaq_0637

Alternate gene names: 159041215

Gene position: 673188-672166 (Counterclockwise)

Preceding gene: 159041216

Following gene: 159041213

Centisome position: 32.4

GC content: 43.89

Gene sequence:

>1023_bases
ATGGTTGATGTTTTAAGTGAACTACATGAGAAGTATGGGGAATTGGTTAATAAGGCTATTGAGAGGTACTTAACCATAGG
TGTTGATCCATCATTCAGGGAGACTGTACTTTACCAAGTGGCTACGGGTGGTAAGAGGATTAGGCCACTAATGGTTATTG
AATCAGCCTTAGCCTGTGGTGGTTCCCTTGAATCAGCCTTACCCTACGCCGCCATAGTTGAGTTAATACATAATTACTCC
CTCATATACGATGACATAATTGATGAGGCGGACTTAAGGAGGAATATGCCAACAGTGAGGAGGAAGTACGGTGACTACGC
GGCAATACTGGTGGGGATATGGTATAGGGAGGCTATTGAGGAGGCGGTACTGGATACAAGGAATCCCAGTGAGGTAGCTA
GGGTTGTTGCTGAGACTATAAAGGCCATTGATGAGGGTGAGAGACTTGACATACTGATGGAGTACTCGGGTAGAAGGGAT
CCTTACTTTATTGAGAATAGACTTGTTAGGGAAATAACCCCAGCCTTAAGGGACCTTTACATAAGAATGATTTCACTTAA
GACTGCTGCATTATTTAAAACATCAATGTGGCTCGGCGGCTACTCGGCGAAATGCGGTAACGAGCAATTGGAGGCGCTGA
GTAATTTCGGGTATAACGTGGGTGTGGCCTTCCAAATAATAGACGATGTACTAGACATATTCGGTGACTTAAGGAAGTTC
GGTAAGGAGATTGGTAAGGACCTTAAGGAACATAAGGTCGGTAACCTAGTTATACTGCTTTCACTCCTTGAGAGTAAGGA
GGCTAATAAGCTACTTAATGTGCTTTCCAAGCAGAGGCCGACTCAAGACGATGTTAAGGAGGCTGTGGAGGTTATTTCAG
CAACTAAGGCTAGGGAGGAGGCTATTAGGATGGCTAATGAATACATGAGTAAGGCCATTAGTGAACTAAGTAAGGTGCCT
AGGAATGAACATACAATGAAGCTGGAGGAACTGGCTAAATTCATAGTTTATAGGGAGTATTGA

Upstream 100 bases:

>100_bases
AGTTGTTTTAGCTAAGTCGCCTAGGGATATTGATAATGAGCTTATAGCAACCCTGCTTCGAGGCGGCTAATACTTTTAAA
CGTTAACTAATTCCGTGACT

Downstream 100 bases:

>100_bases
AGAATTAAGGTTTTAAGAAATTAAATTATATTGAAGTTTAACTTAGGAGTGGCCTTTACCATGGCCATGGTTACTGTTGC
CGCTACCATTACCCTTACCT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MVDVLSELHEKYGELVNKAIERYLTIGVDPSFRETVLYQVATGGKRIRPLMVIESALACGGSLESALPYAAIVELIHNYS
LIYDDIIDEADLRRNMPTVRRKYGDYAAILVGIWYREAIEEAVLDTRNPSEVARVVAETIKAIDEGERLDILMEYSGRRD
PYFIENRLVREITPALRDLYIRMISLKTAALFKTSMWLGGYSAKCGNEQLEALSNFGYNVGVAFQIIDDVLDIFGDLRKF
GKEIGKDLKEHKVGNLVILLSLLESKEANKLLNVLSKQRPTQDDVKEAVEVISATKAREEAIRMANEYMSKAISELSKVP
RNEHTMKLEELAKFIVYREY

Sequences:

>Translated_340_residues
MVDVLSELHEKYGELVNKAIERYLTIGVDPSFRETVLYQVATGGKRIRPLMVIESALACGGSLESALPYAAIVELIHNYS
LIYDDIIDEADLRRNMPTVRRKYGDYAAILVGIWYREAIEEAVLDTRNPSEVARVVAETIKAIDEGERLDILMEYSGRRD
PYFIENRLVREITPALRDLYIRMISLKTAALFKTSMWLGGYSAKCGNEQLEALSNFGYNVGVAFQIIDDVLDIFGDLRKF
GKEIGKDLKEHKVGNLVILLSLLESKEANKLLNVLSKQRPTQDDVKEAVEVISATKAREEAIRMANEYMSKAISELSKVP
RNEHTMKLEELAKFIVYREY
>Mature_340_residues
MVDVLSELHEKYGELVNKAIERYLTIGVDPSFRETVLYQVATGGKRIRPLMVIESALACGGSLESALPYAAIVELIHNYS
LIYDDIIDEADLRRNMPTVRRKYGDYAAILVGIWYREAIEEAVLDTRNPSEVARVVAETIKAIDEGERLDILMEYSGRRD
PYFIENRLVREITPALRDLYIRMISLKTAALFKTSMWLGGYSAKCGNEQLEALSNFGYNVGVAFQIIDDVLDIFGDLRKF
GKEIGKDLKEHKVGNLVILLSLLESKEANKLLNVLSKQRPTQDDVKEAVEVISATKAREEAIRMANEYMSKAISELSKVP
RNEHTMKLEELAKFIVYREY

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=321, Percent_Identity=26.1682242990654, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789578, Length=304, Percent_Identity=30.9210526315789, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786623, Length=249, Percent_Identity=32.1285140562249, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17505681, Length=343, Percent_Identity=25.9475218658892, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24651612, Length=304, Percent_Identity=23.0263157894737, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 38609; Mature: 38609

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVLSELHEKYGELVNKAIERYLTIGVDPSFRETVLYQVATGGKRIRPLMVIESALACG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
GSLESALPYAAIVELIHNYSLIYDDIIDEADLRRNMPTVRRKYGDYAAILVGIWYREAIE
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHH
EAVLDTRNPSEVARVVAETIKAIDEGERLDILMEYSGRRDPYFIENRLVREITPALRDLY
HHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
IRMISLKTAALFKTSMWLGGYSAKCGNEQLEALSNFGYNVGVAFQIIDDVLDIFGDLRKF
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GKEIGKDLKEHKVGNLVILLSLLESKEANKLLNVLSKQRPTQDDVKEAVEVISATKAREE
HHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AIRMANEYMSKAISELSKVPRNEHTMKLEELAKFIVYREY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDVLSELHEKYGELVNKAIERYLTIGVDPSFRETVLYQVATGGKRIRPLMVIESALACG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
GSLESALPYAAIVELIHNYSLIYDDIIDEADLRRNMPTVRRKYGDYAAILVGIWYREAIE
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHH
EAVLDTRNPSEVARVVAETIKAIDEGERLDILMEYSGRRDPYFIENRLVREITPALRDLY
HHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
IRMISLKTAALFKTSMWLGGYSAKCGNEQLEALSNFGYNVGVAFQIIDDVLDIFGDLRKF
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GKEIGKDLKEHKVGNLVILLSLLESKEANKLLNVLSKQRPTQDDVKEAVEVISATKAREE
HHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AIRMANEYMSKAISELSKVPRNEHTMKLEELAKFIVYREY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]