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The map label for this gene is atpA [H]

Identifier: 159040804

GI number: 159040804

Start: 253111

End: 254898

Strand: Reverse

Name: atpA [H]

Synonym: Cmaq_0217

Alternate gene names: 159040804

Gene position: 254898-253111 (Counterclockwise)

Preceding gene: 159040805

Following gene: 159040803

Centisome position: 12.27

GC content: 46.64

Gene sequence:

>1788_bases
ATGATGAGTAGTCAAGGCACCGGTAGGATACTTGTGGTTAATGGCCCAGTAATAAAGGCTGAGTTACCTGGGGCTAAACT
ATATGAGTTAGTGTTCGTGGGTGAATTAGGGTTATTTGGTGAAGTAGTTAGGGTTCAGGGTGAGAATGCTTTCATACAGG
TTTACGAGGATACCACTGGAATAAGGCCAGGTGAACCAGTGGTTAGGACTGGTGAAATGCTTAGTGCCTGGCTTGGACCT
GGGATAATTGGTCAGGTTTATGATGGTGTACAGAGGCCATTGAAGATTATTTTTGATCAAACTGGGCGCCCATTCATAGC
CAGGGGTATTAATTATGATAGAGCCCCACCATTAGACTTCAGTAGGAAGTGGAGGTGGATACCTAAGGTTAAGATTGGTG
ATAAGGTTAACGTCGGCACGGTACTTGGTATTGTACCTGAGACCCAATTAATAGAGCATAGGATACTTTATCCCCCATTA
TATAAGCCCGGCATCATAAAGTACATTGCCCCTGAGGGTGACTACACGCTTAATGATGATATCGCGGAGGTAGAGACCAG
TGATGGCTTAATTAAGGTTAAGATGTGGCATAAGTGGCCCGTTAGGAGACCAAGGCCATTCCAGGAGAAGCTGCCTCCAA
GTGACCCCTTAATAACTGGAATAAGGGTAATTGATACTGTTTTCCCAATAGCTAAGGGTGGGGCAGCCTCAATACCAGGT
CCATTTGGCTCAGGTAAGACGGTGACCATTAGGTCATTGATGCTTTACGCAATGACCCAGTACAGTGTCCCAGTACTATG
TGGTGAGAGGGGTAATGAGGCTGCTGATGCATTGCAGGGATTACTTAAATTATCTGACCCAGCCACTGGGCGGCCGTTGC
TTGAGAGGGAGACGATAATAGTTAATACATCCAATATGCCTGTTGCAGCCAGGGAGGCAAGTATATACATGGGTGCAACA
ATAGCTGAGTACTTCAGGGATCAGGGCTACGACGTATTATTGATGGCTGATTCCACAAGCCGTTGGGCTGAGGCTATGCG
TGAGGTGGCGTTGAGGATTGGTGAAATGCCCAGTGAGGAGGGGTTCCCAGCCTACTTACCCACTAGGCTTGCTGAATTCT
ATGAGAGGGCTGGTAAGGTTAAGTTACTTAACGGTGGTTTAGGTTCATTAACCATAGCAGCCTCAGTAAGCCCACCTGGT
GGTGACTTCACTGAGCCGGTGACTAGCCATACGTTAAGGTTCATTGGAGCCTTCTGGCCCCTTGATGCTAGATTAGCCTA
CTCTAGGCATTACCCAGCCATTAATTGGCTTCAAGGCTTCAGCAGATACGTGGACTCAGTAGCCTCCTGGTACAGTAAGA
CTGTTGGTGAGGATTGGGTTGAGTTAAGGAGAATAGCCATAGAGGTATTGACTAGGGAGGCTGAGTTATCTGAAATTGTT
AGGATACTTGGAAGCGAGGCCTTAAGTGAACAGGAGAAGCATATCCTTAACGTTGCATCAATGATACGTGAAGGCTTCCT
TAAACAGGATGCATTCAACCCAGTGGATACGCCATCAGCGCCGGAGAAGCAGTATTGGCTACTTAGATTAATGATAACCT
ACTATAGGGTTGGCTCAGAGGCCATTAACGCTGGTGTACCGGCTAATGCAATTAGGGAACTGGACTCAGTGAGGAGGCTT
ATTAGGCTTAAGATGGAGGTTAAGAGCAGTGACTATAAGGTCCTGGCTGATTACGAGAGGAAGCTAATTGATGATATAAG
GGGACTCATGGCTAAGTTCAGTAAATGA

Upstream 100 bases:

>100_bases
GTTCAGTGACATATGAGGCAACGATCGATGACGTGTTAAACCGCATGATAGACTATATAAGGAGTATAATTAAGGAGGTT
GCTGATGAGGTGGTTAAGCA

Downstream 100 bases:

>100_bases
TGCTTAAAAATAACTAATACTTATTGCTCCTTAAAAAGCCGGTGGTATGAAGAATCATGTGGTGATAAATAAGGCATTAC
TCATCAGTCTGGGGCATGGC

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MMSSQGTGRILVVNGPVIKAELPGAKLYELVFVGELGLFGEVVRVQGENAFIQVYEDTTGIRPGEPVVRTGEMLSAWLGP
GIIGQVYDGVQRPLKIIFDQTGRPFIARGINYDRAPPLDFSRKWRWIPKVKIGDKVNVGTVLGIVPETQLIEHRILYPPL
YKPGIIKYIAPEGDYTLNDDIAEVETSDGLIKVKMWHKWPVRRPRPFQEKLPPSDPLITGIRVIDTVFPIAKGGAASIPG
PFGSGKTVTIRSLMLYAMTQYSVPVLCGERGNEAADALQGLLKLSDPATGRPLLERETIIVNTSNMPVAAREASIYMGAT
IAEYFRDQGYDVLLMADSTSRWAEAMREVALRIGEMPSEEGFPAYLPTRLAEFYERAGKVKLLNGGLGSLTIAASVSPPG
GDFTEPVTSHTLRFIGAFWPLDARLAYSRHYPAINWLQGFSRYVDSVASWYSKTVGEDWVELRRIAIEVLTREAELSEIV
RILGSEALSEQEKHILNVASMIREGFLKQDAFNPVDTPSAPEKQYWLLRLMITYYRVGSEAINAGVPANAIRELDSVRRL
IRLKMEVKSSDYKVLADYERKLIDDIRGLMAKFSK

Sequences:

>Translated_595_residues
MMSSQGTGRILVVNGPVIKAELPGAKLYELVFVGELGLFGEVVRVQGENAFIQVYEDTTGIRPGEPVVRTGEMLSAWLGP
GIIGQVYDGVQRPLKIIFDQTGRPFIARGINYDRAPPLDFSRKWRWIPKVKIGDKVNVGTVLGIVPETQLIEHRILYPPL
YKPGIIKYIAPEGDYTLNDDIAEVETSDGLIKVKMWHKWPVRRPRPFQEKLPPSDPLITGIRVIDTVFPIAKGGAASIPG
PFGSGKTVTIRSLMLYAMTQYSVPVLCGERGNEAADALQGLLKLSDPATGRPLLERETIIVNTSNMPVAAREASIYMGAT
IAEYFRDQGYDVLLMADSTSRWAEAMREVALRIGEMPSEEGFPAYLPTRLAEFYERAGKVKLLNGGLGSLTIAASVSPPG
GDFTEPVTSHTLRFIGAFWPLDARLAYSRHYPAINWLQGFSRYVDSVASWYSKTVGEDWVELRRIAIEVLTREAELSEIV
RILGSEALSEQEKHILNVASMIREGFLKQDAFNPVDTPSAPEKQYWLLRLMITYYRVGSEAINAGVPANAIRELDSVRRL
IRLKMEVKSSDYKVLADYERKLIDDIRGLMAKFSK
>Mature_595_residues
MMSSQGTGRILVVNGPVIKAELPGAKLYELVFVGELGLFGEVVRVQGENAFIQVYEDTTGIRPGEPVVRTGEMLSAWLGP
GIIGQVYDGVQRPLKIIFDQTGRPFIARGINYDRAPPLDFSRKWRWIPKVKIGDKVNVGTVLGIVPETQLIEHRILYPPL
YKPGIIKYIAPEGDYTLNDDIAEVETSDGLIKVKMWHKWPVRRPRPFQEKLPPSDPLITGIRVIDTVFPIAKGGAASIPG
PFGSGKTVTIRSLMLYAMTQYSVPVLCGERGNEAADALQGLLKLSDPATGRPLLERETIIVNTSNMPVAAREASIYMGAT
IAEYFRDQGYDVLLMADSTSRWAEAMREVALRIGEMPSEEGFPAYLPTRLAEFYERAGKVKLLNGGLGSLTIAASVSPPG
GDFTEPVTSHTLRFIGAFWPLDARLAYSRHYPAINWLQGFSRYVDSVASWYSKTVGEDWVELRRIAIEVLTREAELSEIV
RILGSEALSEQEKHILNVASMIREGFLKQDAFNPVDTPSAPEKQYWLLRLMITYYRVGSEAINAGVPANAIRELDSVRRL
IRLKMEVKSSDYKVLADYERKLIDDIRGLMAKFSK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=594, Percent_Identity=43.9393939393939, Blast_Score=488, Evalue=1e-138,
Organism=Homo sapiens, GI32189394, Length=350, Percent_Identity=31.4285714285714, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI19913428, Length=217, Percent_Identity=26.7281105990783, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI19913426, Length=235, Percent_Identity=27.2340425531915, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI50345984, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4757810, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790170, Length=320, Percent_Identity=32.1875, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788251, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790172, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=600, Percent_Identity=44, Blast_Score=487, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25144756, Length=312, Percent_Identity=32.0512820512821, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=217, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17570191, Length=239, Percent_Identity=27.1966527196653, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71988080, Length=259, Percent_Identity=24.7104247104247, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71988063, Length=259, Percent_Identity=24.7104247104247, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71988074, Length=259, Percent_Identity=24.7104247104247, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320016, Length=305, Percent_Identity=43.9344262295082, Blast_Score=257, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6322581, Length=329, Percent_Identity=32.8267477203647, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=238, Percent_Identity=28.1512605042017, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319370, Length=241, Percent_Identity=26.9709543568465, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583988, Length=596, Percent_Identity=43.7919463087248, Blast_Score=496, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24583986, Length=596, Percent_Identity=43.7919463087248, Blast_Score=496, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24583984, Length=596, Percent_Identity=43.7919463087248, Blast_Score=496, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24583992, Length=596, Percent_Identity=42.9530201342282, Blast_Score=493, Evalue=1e-139,
Organism=Drosophila melanogaster, GI20129479, Length=564, Percent_Identity=44.6808510638298, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI24638766, Length=302, Percent_Identity=32.4503311258278, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28574560, Length=302, Percent_Identity=32.1192052980132, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281361666, Length=239, Percent_Identity=26.3598326359833, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646341, Length=239, Percent_Identity=26.3598326359833, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136796, Length=239, Percent_Identity=26.3598326359833, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658560, Length=301, Percent_Identity=25.9136212624585, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 66251; Mature: 66251

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSQGTGRILVVNGPVIKAELPGAKLYELVFVGELGLFGEVVRVQGENAFIQVYEDTTG
CCCCCCCCEEEEEECCEEEEECCCCCEEEEEEECCCCCCCEEEEEECCCEEEEEEECCCC
IRPGEPVVRTGEMLSAWLGPGIIGQVYDGVQRPLKIIFDQTGRPFIARGINYDRAPPLDF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
SRKWRWIPKVKIGDKVNVGTVLGIVPETQLIEHRILYPPLYKPGIIKYIAPEGDYTLNDD
CCCCEECCCEECCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCC
IAEVETSDGLIKVKMWHKWPVRRPRPFQEKLPPSDPLITGIRVIDTVFPIAKGGAASIPG
HHHEECCCCEEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PFGSGKTVTIRSLMLYAMTQYSVPVLCGERGNEAADALQGLLKLSDPATGRPLLERETII
CCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEE
VNTSNMPVAAREASIYMGATIAEYFRDQGYDVLLMADSTSRWAEAMREVALRIGEMPSEE
EECCCCCEEECCCCEEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
GFPAYLPTRLAEFYERAGKVKLLNGGLGSLTIAASVSPPGGDFTEPVTSHTLRFIGAFWP
CCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
LDARLAYSRHYPAINWLQGFSRYVDSVASWYSKTVGEDWVELRRIAIEVLTREAELSEIV
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILGSEALSEQEKHILNVASMIREGFLKQDAFNPVDTPSAPEKQYWLLRLMITYYRVGSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHH
AINAGVPANAIRELDSVRRLIRLKMEVKSSDYKVLADYERKLIDDIRGLMAKFSK
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSSQGTGRILVVNGPVIKAELPGAKLYELVFVGELGLFGEVVRVQGENAFIQVYEDTTG
CCCCCCCCEEEEEECCEEEEECCCCCEEEEEEECCCCCCCEEEEEECCCEEEEEEECCCC
IRPGEPVVRTGEMLSAWLGPGIIGQVYDGVQRPLKIIFDQTGRPFIARGINYDRAPPLDF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
SRKWRWIPKVKIGDKVNVGTVLGIVPETQLIEHRILYPPLYKPGIIKYIAPEGDYTLNDD
CCCCEECCCEECCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCC
IAEVETSDGLIKVKMWHKWPVRRPRPFQEKLPPSDPLITGIRVIDTVFPIAKGGAASIPG
HHHEECCCCEEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PFGSGKTVTIRSLMLYAMTQYSVPVLCGERGNEAADALQGLLKLSDPATGRPLLERETII
CCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEE
VNTSNMPVAAREASIYMGATIAEYFRDQGYDVLLMADSTSRWAEAMREVALRIGEMPSEE
EECCCCCEEECCCCEEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
GFPAYLPTRLAEFYERAGKVKLLNGGLGSLTIAASVSPPGGDFTEPVTSHTLRFIGAFWP
CCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
LDARLAYSRHYPAINWLQGFSRYVDSVASWYSKTVGEDWVELRRIAIEVLTREAELSEIV
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILGSEALSEQEKHILNVASMIREGFLKQDAFNPVDTPSAPEKQYWLLRLMITYYRVGSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHH
AINAGVPANAIRELDSVRRLIRLKMEVKSSDYKVLADYERKLIDDIRGLMAKFSK
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA