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The map label for this gene is ffh [H]

Identifier: 158425575

GI number: 158425575

Start: 4516842

End: 4518377

Strand: Direct

Name: ffh [H]

Synonym: AZC_3951

Alternate gene names: 158425575

Gene position: 4516842-4518377 (Clockwise)

Preceding gene: 158425572

Following gene: 158425576

Centisome position: 84.12

GC content: 69.08

Gene sequence:

>1536_bases
ATGTTCGACAGCCTTTCAGACCGCCTTGGCGGCATACTCGACAAGCTGAAGCGGCGCGGCGCTCTCACCGAGGCCGACGT
CGGCGAGGCCATGCGCGAGGTCCGGCGGGCGCTGATCGAGGCGGACGTCGCCCTCGACGTGGTGCGCTCCTTCACGGACA
AGGTGCGCCAGCGCGCCGTGGGCGTCGAGGTCATCAAGTCGGTGACCCCCGGCCAGATGGTCGTGAAGATCGTCCATGAC
GTGCTGGTGGAGACGCTGGGCTCCGACGCCGATCCCATCGACCTCAATGCGCCCGCCCCCGTCCCGATCCTCATGGTCGG
CCTCCAGGGCTCGGGCAAGACCACCACCACCGCCAAGATCGCCAAGCGCCTGACCGAGCGCGGCAACCGCCGCGTGCTCA
TGGCCTCGCTCGACACCCGCCGCCCGGCGGCCATGGAGCAGCTGGCGACGCTGGGCACGCAGGTGGAGGTGAACACCCTT
CCCATCGTGCCCGGCCAGAGCGCCGTGCAGATCGCCAAGCGGGCCATGGATGCCGCCCGCTTCGGCAATTACGACGTGGT
GATCCTCGACACCGCCGGCCGCGTCACGCTGGATGAAGCGCTGATGGCGGAAGTGGCCGAGGTGAAGGCCATCACCAACC
CGCACGAAGTGCTGCTGGTGGCCGACAGCCTCACCGGCCAGGACGCGGTGAACACCGCGAAAGCCTTCGACAGCCGCGTC
TCCATCACCGGCATCGTGCTGACCCGCGCCGACGGCGACGGGCGCGGCGGCGCCGCGCTCTCCATGCGCGCGGTCACCGG
CAAGCCCATCAAGCTGCTGGGCACGGGCGAGAAGATGGACGGGCTGGAGGATTTCGATCCCCAGCGGGTCGCCGGCCGTA
TCCTCGGCATGGGCGACGTGGTGGCCCTCGTGGAGAAGGCCGCCGAGAATCTCGACATCGAGAAGGCCAAGGCCACCGCC
GAGCGGATGCGCAAGGGCGTCTTCGATCTGGAAGACCTGCGCGACCAGCTCTTCCAGATGCAGAAGATGGGCGGCATGGG
CGGCCTGATGGGGATGCTGCCCGGCATCGCCAAGGTGAAGAACCAGATCGCCGCTGCCAATCTCGACGACAAGGTGTTCA
AGCGCCAGGTCGCCATCATCAATTCCATGACCCGGCAGGAGCGGCGCAATCCGAAGGTGCTCGACGCCTCGCGCAAGAAG
CGCATCGCCTCCGGCTCTGGCACCAAGGTCGAGGAGATCAACCGCCTCATCAAGATGCACCGCCAGATGGCGGACGTGAT
GAAGGCCATGGGCGGGGCCGCCGGCAAGCGCGGTCCGCTCGCCGGTCTCGCCAGCATGATGGGCATGGGGGCCGGCGGCC
CCTCGCCGGAAATGCTCCAGCAGATGGCCGAGAAGATGCCGGGCGGCCTGCCCGGTGGCGGCGGCCTCCCCCCGACCTTC
CCCGGTGGCCTGCCCGGCCTCGGAAAGGGCCTGCCTCCGGGCCTGCCCAAGGGCTTCCCCGGCCTGCCCGGCCTCGGCGG
CCCGAAGAAGAAATGA

Upstream 100 bases:

>100_bases
ACCCCATCTGTGGCGCAGCAGAGAGACAAGACCCGGCGGGCCAGCCGCCGACCTTGCGAACCCCAACTCCGGTCCCGGCC
GGAGTGATCAGGACGGACCC

Downstream 100 bases:

>100_bases
CGCCCGCCGCTTGCTCCCATGGGGATCAGCGGTCGGCCGATTGAAATCAAGACACACGAACACGAAGACACTGAAAGGAA
AGTCCCATGTCCCTCAAGAT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MFDSLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDKVRQRAVGVEVIKSVTPGQMVVKIVHD
VLVETLGSDADPIDLNAPAPVPILMVGLQGSGKTTTTAKIAKRLTERGNRRVLMASLDTRRPAAMEQLATLGTQVEVNTL
PIVPGQSAVQIAKRAMDAARFGNYDVVILDTAGRVTLDEALMAEVAEVKAITNPHEVLLVADSLTGQDAVNTAKAFDSRV
SITGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDGLEDFDPQRVAGRILGMGDVVALVEKAAENLDIEKAKATA
ERMRKGVFDLEDLRDQLFQMQKMGGMGGLMGMLPGIAKVKNQIAAANLDDKVFKRQVAIINSMTRQERRNPKVLDASRKK
RIASGSGTKVEEINRLIKMHRQMADVMKAMGGAAGKRGPLAGLASMMGMGAGGPSPEMLQQMAEKMPGGLPGGGGLPPTF
PGGLPGLGKGLPPGLPKGFPGLPGLGGPKKK

Sequences:

>Translated_511_residues
MFDSLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDKVRQRAVGVEVIKSVTPGQMVVKIVHD
VLVETLGSDADPIDLNAPAPVPILMVGLQGSGKTTTTAKIAKRLTERGNRRVLMASLDTRRPAAMEQLATLGTQVEVNTL
PIVPGQSAVQIAKRAMDAARFGNYDVVILDTAGRVTLDEALMAEVAEVKAITNPHEVLLVADSLTGQDAVNTAKAFDSRV
SITGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDGLEDFDPQRVAGRILGMGDVVALVEKAAENLDIEKAKATA
ERMRKGVFDLEDLRDQLFQMQKMGGMGGLMGMLPGIAKVKNQIAAANLDDKVFKRQVAIINSMTRQERRNPKVLDASRKK
RIASGSGTKVEEINRLIKMHRQMADVMKAMGGAAGKRGPLAGLASMMGMGAGGPSPEMLQQMAEKMPGGLPGGGGLPPTF
PGGLPGLGKGLPPGLPKGFPGLPGLGGPKKK
>Mature_511_residues
MFDSLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDKVRQRAVGVEVIKSVTPGQMVVKIVHD
VLVETLGSDADPIDLNAPAPVPILMVGLQGSGKTTTTAKIAKRLTERGNRRVLMASLDTRRPAAMEQLATLGTQVEVNTL
PIVPGQSAVQIAKRAMDAARFGNYDVVILDTAGRVTLDEALMAEVAEVKAITNPHEVLLVADSLTGQDAVNTAKAFDSRV
SITGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDGLEDFDPQRVAGRILGMGDVVALVEKAAENLDIEKAKATA
ERMRKGVFDLEDLRDQLFQMQKMGGMGGLMGMLPGIAKVKNQIAAANLDDKVFKRQVAIINSMTRQERRNPKVLDASRKK
RIASGSGTKVEEINRLIKMHRQMADVMKAMGGAAGKRGPLAGLASMMGMGAGGPSPEMLQQMAEKMPGGLPGGGGLPPTF
PGGLPGLGKGLPPGLPKGFPGLPGLGGPKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=511, Percent_Identity=30.1369863013699, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI226371618, Length=408, Percent_Identity=31.8627450980392, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=33.9622641509434, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI23308697, Length=316, Percent_Identity=29.746835443038, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI295424842, Length=316, Percent_Identity=29.746835443038, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=50.7075471698113, Blast_Score=413, Evalue=1e-116,
Organism=Escherichia coli, GI1789874, Length=211, Percent_Identity=38.3886255924171, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=466, Percent_Identity=29.1845493562232, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI193206261, Length=215, Percent_Identity=34.4186046511628, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=459, Percent_Identity=30.9368191721133, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6320498, Length=314, Percent_Identity=25.4777070063694, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647949, Length=464, Percent_Identity=29.0948275862069, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24641198, Length=306, Percent_Identity=30.3921568627451, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53903; Mature: 53903

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDKVRQRAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVEVIKSVTPGQMVVKIVHDVLVETLGSDADPIDLNAPAPVPILMVGLQGSGKTTTTAKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
AKRLTERGNRRVLMASLDTRRPAAMEQLATLGTQVEVNTLPIVPGQSAVQIAKRAMDAAR
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHH
FGNYDVVILDTAGRVTLDEALMAEVAEVKAITNPHEVLLVADSLTGQDAVNTAKAFDSRV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCE
SITGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDGLEDFDPQRVAGRILGMGDV
EEEEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
VALVEKAAENLDIEKAKATAERMRKGVFDLEDLRDQLFQMQKMGGMGGLMGMLPGIAKVK
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NQIAAANLDDKVFKRQVAIINSMTRQERRNPKVLDASRKKRIASGSGTKVEEINRLIKMH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
RQMADVMKAMGGAAGKRGPLAGLASMMGMGAGGPSPEMLQQMAEKMPGGLPGGGGLPPTF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
PGGLPGLGKGLPPGLPKGFPGLPGLGGPKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDSLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDKVRQRAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVEVIKSVTPGQMVVKIVHDVLVETLGSDADPIDLNAPAPVPILMVGLQGSGKTTTTAKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
AKRLTERGNRRVLMASLDTRRPAAMEQLATLGTQVEVNTLPIVPGQSAVQIAKRAMDAAR
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHH
FGNYDVVILDTAGRVTLDEALMAEVAEVKAITNPHEVLLVADSLTGQDAVNTAKAFDSRV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCE
SITGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDGLEDFDPQRVAGRILGMGDV
EEEEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
VALVEKAAENLDIEKAKATAERMRKGVFDLEDLRDQLFQMQKMGGMGGLMGMLPGIAKVK
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NQIAAANLDDKVFKRQVAIINSMTRQERRNPKVLDASRKKRIASGSGTKVEEINRLIKMH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
RQMADVMKAMGGAAGKRGPLAGLASMMGMGAGGPSPEMLQQMAEKMPGGLPGGGGLPPTF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
PGGLPGLGKGLPPGLPKGFPGLPGLGGPKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]