Click here to switch to the map view.

The map label for this gene is cobK [H]

Identifier: 158425565

GI number: 158425565

Start: 4506222

End: 4507010

Strand: Reverse

Name: cobK [H]

Synonym: AZC_3941

Alternate gene names: 158425565

Gene position: 4507010-4506222 (Counterclockwise)

Preceding gene: 158425569

Following gene: 158425554

Centisome position: 83.93

GC content: 70.72

Gene sequence:

>789_bases
ATGCCGCGTCACATCCTCATCCTTGGGGGGACAGGGGAGGCCCGGCGTCTCGCCGCGCGACTCGCAGGCGAGGAGAACCT
CCATGCCATTGTGTCGCTTGCGGGCCGCACCGAAAACCCCGCGCAGATGCCTGTCCCCGTCCGCGTGGGCGGCTTCGGCG
GCATAGCTGGCCTGCGCGACTATCTTGCCGCCGAGGCTATTTCGGCGGTGGTCGACGCCACCCATCCCTATGCGGCGCAG
ATGTCGCGCCATGCGGCCGCCGCCTGCGCGGCCTTGGGCGTGCCGCTTCTGGCCCTGCGCCGCCAGCCGTGGAAGCCGGT
GGATGGTGACCGCTGGCGGGAGGTGGAGGGCGTTGCTGGCGCCCTCGCGGCACTGGGTGAGACACCGCGCCGCGTCTTCC
TCGCGCTCGGCCGCAACGAGGTGCGCGCCTTCGAGGCCGCGCCCCGGCACAGCTATCTGGTACGCAGCGTCGATGCCGTC
GAGCCGCCCCTGGCCGTGCCCAACGCCAACTATGTGGTGGCACGCGGCCCCTTCACGGCTGAAGGCGATCTGGACCTGCT
GCGCGATCATGGCATCGAGATCATCGTCGCCAAAAACAGCGGCGGCCCCGCCACCTACGGCAAGATGGAGGCGGCCCGCG
CGCTGGGCCTCGAGGTGATCCTGCTGCGCCGGCCGGACGTGCCCGATGTGCCGGCGGTGGAGACGGTGGAAGAGGTGGCG
CACTGGCTCGAAAGGACGAACGCGCCCGACACCCAGAGCCGGACCCGCGCACACAGAAGCGCGCTTTAA

Upstream 100 bases:

>100_bases
GTCCGCGCCATCCTCACCGATGCCGACGATGGACAGCCAGGGCCGTGCTGCGGCAGTGTCGCCCGCCATGTCAGGTCCCT
CGCTCAGCCAAGCCGCATCC

Downstream 100 bases:

>100_bases
TGCCCCGGCATGGTCAGCACGAGCGGGCCGTTGCGGGTGGCGACCACCGTGTGCTCGTACTGGACCGTGAGGGCGCGAGG
TTCGCTATAGAGCGTCCACG

Product: precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPRHILILGGTGEARRLAARLAGEENLHAIVSLAGRTENPAQMPVPVRVGGFGGIAGLRDYLAAEAISAVVDATHPYAAQ
MSRHAAAACAALGVPLLALRRQPWKPVDGDRWREVEGVAGALAALGETPRRVFLALGRNEVRAFEAAPRHSYLVRSVDAV
EPPLAVPNANYVVARGPFTAEGDLDLLRDHGIEIIVAKNSGGPATYGKMEAARALGLEVILLRRPDVPDVPAVETVEEVA
HWLERTNAPDTQSRTRAHRSAL

Sequences:

>Translated_262_residues
MPRHILILGGTGEARRLAARLAGEENLHAIVSLAGRTENPAQMPVPVRVGGFGGIAGLRDYLAAEAISAVVDATHPYAAQ
MSRHAAAACAALGVPLLALRRQPWKPVDGDRWREVEGVAGALAALGETPRRVFLALGRNEVRAFEAAPRHSYLVRSVDAV
EPPLAVPNANYVVARGPFTAEGDLDLLRDHGIEIIVAKNSGGPATYGKMEAARALGLEVILLRRPDVPDVPAVETVEEVA
HWLERTNAPDTQSRTRAHRSAL
>Mature_261_residues
PRHILILGGTGEARRLAARLAGEENLHAIVSLAGRTENPAQMPVPVRVGGFGGIAGLRDYLAAEAISAVVDATHPYAAQM
SRHAAAACAALGVPLLALRRQPWKPVDGDRWREVEGVAGALAALGETPRRVFLALGRNEVRAFEAAPRHSYLVRSVDAVE
PPLAVPNANYVVARGPFTAEGDLDLLRDHGIEIIVAKNSGGPATYGKMEAARALGLEVILLRRPDVPDVPAVETVEEVAH
WLERTNAPDTQSRTRAHRSAL

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 27954; Mature: 27823

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRHILILGGTGEARRLAARLAGEENLHAIVSLAGRTENPAQMPVPVRVGGFGGIAGLRD
CCCEEEEECCCCHHHHHHHHHCCCCCHHHHHEECCCCCCCCCCCCEEEECCCCCHHHHHH
YLAAEAISAVVDATHPYAAQMSRHAAAACAALGVPLLALRRQPWKPVDGDRWREVEGVAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALAALGETPRRVFLALGRNEVRAFEAAPRHSYLVRSVDAVEPPLAVPNANYVVARGPFTA
HHHHHCCCCHHEEEECCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
EGDLDLLRDHGIEIIVAKNSGGPATYGKMEAARALGLEVILLRRPDVPDVPAVETVEEVA
CCCHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHH
HWLERTNAPDTQSRTRAHRSAL
HHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PRHILILGGTGEARRLAARLAGEENLHAIVSLAGRTENPAQMPVPVRVGGFGGIAGLRD
CCEEEEECCCCHHHHHHHHHCCCCCHHHHHEECCCCCCCCCCCCEEEECCCCCHHHHHH
YLAAEAISAVVDATHPYAAQMSRHAAAACAALGVPLLALRRQPWKPVDGDRWREVEGVAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALAALGETPRRVFLALGRNEVRAFEAAPRHSYLVRSVDAVEPPLAVPNANYVVARGPFTA
HHHHHCCCCHHEEEECCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
EGDLDLLRDHGIEIIVAKNSGGPATYGKMEAARALGLEVILLRRPDVPDVPAVETVEEVA
CCCHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHH
HWLERTNAPDTQSRTRAHRSAL
HHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]