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The map label for this gene is tsr [C]

Identifier: 158425471

GI number: 158425471

Start: 4397449

End: 4399548

Strand: Reverse

Name: tsr [C]

Synonym: AZC_3847

Alternate gene names: 158425471

Gene position: 4399548-4397449 (Counterclockwise)

Preceding gene: 158425473

Following gene: 158425470

Centisome position: 81.93

GC content: 67.43

Gene sequence:

>2100_bases
ATGCGTTTGTCGATTAATGCAACGCTGCTCAGCCTTTTCTGCTTCACCACCCTCATAGTTACGATGCTCTGCGCCGTGGC
GCTGCGAAGCGCTTACGGCGCGTATGCCTCAGCCAGACAGGCGACCGCCGTCGCCCATATCGACAGAGATATCTATGTGG
CACTCGCTAATTTCCGCTTCGAGCGCGGCGAGGTCGGCATCGCCCTCGCGCTCGCCAGCGACAAGAACCAGCGCAATGTT
GCCAACATCGCGAGCCGCCGCGAGAAGGTGAAGCACGCGCTCGAGGCCGCGCTCGTTGCCTTTAAGACCTATCCCTTGGC
GGATGCCAAATCGGTAGTGCTTATGCGGGACATAGAAAGCCAGTTCGAGACCGTGAAGGACCTGCGCCGCCAGGTGGACG
ACCAGCTCGCGCTGGCGCCGGAGCGCCGCGATGGCTCGGTGGGCCAGCGGTTCGCCGCCGACGGCGGCAAGCTGCTGGAC
ACGCTGGAGCGCCTGTCCACGGAAGTGGAGGCCGACATCCGCTCGCTCGATCCCACGCTGTCGCAGCTCATCCTCGCCCG
CGCCATGGGTTGGGCCACGCGCACCTATACCGGCATCTCCACGCTGCTCATCAATGCCGCCGTCGCGCAGGACCGCCCCC
TCACCGCCGAGGAGACGAAGTCGCTCTTCGCCAATGACGCCAAGGCGGATGTGGCCTGGGGCGCGGTGGTCGAGATCGCT
ATGGCCGACAATGCACCGCCCGCTCTGCGCAAGGCCGCCCAGACCGCGCAGGACTTCTATTTCGCGGGCACGTTCAAGAC
GCTGCGCGACGGCATCGTCAACCGCATCACCCGTGGCGAGAAGAGCGGCGTCTCCCTTCCGGACTGGCGCCAGCCCATCG
AGATCGGTCTCGCCAACTTCGCCGATGTGGCGGGCGTCGCCGTGAACAGCCTCGCCGATATCGCCGACGCCAATGAGGAC
ACAGCCCGCACCACGGCCCTCATCTATGCCGTCGTGCTGCTCGTTTCCCTTGCCCTCGCGGGCGCGGGCCTCGCGGTGGT
CGTCGGCCGCGTGGTGCGGCCCATCTCGCGCCTCACCGCCGTGATGGAGGACGTCGCCGGCGGGCATCTGGAGGTCGAGG
TACCGGGCACGGCCCGCCACGACGAGATCGGCGCCATGGCCAAGACGCTCCTCATCTTCAAGGAGAGCCTGCTGCGCAAC
CGGCAGATGGAGCGCGAGGCGGAGGAAAACCGTCGCGCCACGGAGGCCCAGCGCCGCGCCGCCATGCTGGACCTCGCCGC
GCGCTTCGAGACGGCCGTCGGCGGCATCATCGGTCAGGTGGCCAGTTCGTCCGGCGTCCTGTTCCAGACCGCCCAGTCCA
TGAGCCGGGCGGCGGAGCAGACCTCCACCCGCTCCACAGCCGTGGCCGCGGCGGCGGAGGAGGCCTCCACCAACGTGATC
ATGGTCGCTTCTTCGGCGGAGGAGCTGGGTGCCTCGGTGGAGGAGATTTCCCGCCAGGTGATGCAGTCCTCGCAGATGTC
CTCGAGCGCCGTGGCCGAGGCGGACCGGACCGGCGCGGTGATGCGCGAGCTCGCCCAGGCCGCGGCCCGCATCGGCGCGG
TGGTGGAGCTCATCAACACCATCGCCTCCCAGACCAACCTTCTGGCGCTGAACGCGACCATCGAGGCCGCCCGCGCCGGA
GACGCCGGCAAGGGCTTCGCCGTGGTCGCCTCCGAAGTGAAGGAACTGGCCAACCAGACCGGCAAGGCGACGGAAGAGAT
CGCCGCGCAGGTGAATGCCATCCAGTCCACCACGCAGGAGGCGGTGAAGGTCATCGAGAGCGTGGGCCAGCAGATCCGCA
GCATGAGCGACGTGGCCACCGGCATTTCGGCCGCCGTGGAGGAACAGGGCATCGCCACGCGCGAGATCGTCCGCAATGTG
GATCAGGCGGCCACCGGCACCAATTCCGTGACCGGCCATATCGCCGATGTCGCCCGCACGGCACAGGAAACGGGAGCCGC
GGCCCACGAGGTGCTCAGCGCCTCCTCGGCCCTCAGCGATCAGGCCAAGCAGTTGGAAGTGGAGATGCGCCGCTTCTTGA
ACACTATACGTTCATCCTGA

Upstream 100 bases:

>100_bases
ATTATTGGACCGAGCAAAAAACTTCTGATTTCTCAGAACTAAATGCCAGCCCCCACAAAAGTCATCAGAATTACCGGGAA
TTCGTGTAGGAGTGTTTATT

Downstream 100 bases:

>100_bases
GCTTAACCTACAGACGGCCACGTGCTCGACGAGTTCGCGCGGGAGTGCTTGGCCATCCGCATTGAGCGCAAGCCGAACTC
GACCGCGGTCATCGACGTGC

Product: histidine kinase

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MRLSINATLLSLFCFTTLIVTMLCAVALRSAYGAYASARQATAVAHIDRDIYVALANFRFERGEVGIALALASDKNQRNV
ANIASRREKVKHALEAALVAFKTYPLADAKSVVLMRDIESQFETVKDLRRQVDDQLALAPERRDGSVGQRFAADGGKLLD
TLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANED
TARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISRLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRN
RQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLFQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAG
DAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNV
DQAATGTNSVTGHIADVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLNTIRSS

Sequences:

>Translated_699_residues
MRLSINATLLSLFCFTTLIVTMLCAVALRSAYGAYASARQATAVAHIDRDIYVALANFRFERGEVGIALALASDKNQRNV
ANIASRREKVKHALEAALVAFKTYPLADAKSVVLMRDIESQFETVKDLRRQVDDQLALAPERRDGSVGQRFAADGGKLLD
TLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANED
TARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISRLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRN
RQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLFQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAG
DAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNV
DQAATGTNSVTGHIADVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLNTIRSS
>Mature_699_residues
MRLSINATLLSLFCFTTLIVTMLCAVALRSAYGAYASARQATAVAHIDRDIYVALANFRFERGEVGIALALASDKNQRNV
ANIASRREKVKHALEAALVAFKTYPLADAKSVVLMRDIESQFETVKDLRRQVDDQLALAPERRDGSVGQRFAADGGKLLD
TLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANED
TARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISRLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRN
RQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLFQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAG
DAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNV
DQAATGTNSVTGHIADVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLNTIRSS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=364, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788195, Length=236, Percent_Identity=31.7796610169492, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787690, Length=248, Percent_Identity=28.6290322580645, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789453, Length=179, Percent_Identity=34.6368715083799, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788194, Length=220, Percent_Identity=29.0909090909091, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74054; Mature: 74054

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSINATLLSLFCFTTLIVTMLCAVALRSAYGAYASARQATAVAHIDRDIYVALANFRF
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEE
ERGEVGIALALASDKNQRNVANIASRREKVKHALEAALVAFKTYPLADAKSVVLMRDIES
ECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QFETVKDLRRQVDDQLALAPERRDGSVGQRFAADGGKLLDTLERLSTEVEADIRSLDPTL
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
SQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHEEE
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ADVAGVAVNSLADIADANEDTARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISRLTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRNRQMEREAEENRRATEAQRRA
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLDLAARFETAVGGIIGQVASSSGVLFQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINT
EEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASQTNLLALNATIEAARAGDAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQE
HHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNVDQAATGTNSVTGHIADVART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AQETGAAAHEVLSASSALSDQAKQLEVEMRRFLNTIRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLSINATLLSLFCFTTLIVTMLCAVALRSAYGAYASARQATAVAHIDRDIYVALANFRF
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEE
ERGEVGIALALASDKNQRNVANIASRREKVKHALEAALVAFKTYPLADAKSVVLMRDIES
ECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QFETVKDLRRQVDDQLALAPERRDGSVGQRFAADGGKLLDTLERLSTEVEADIRSLDPTL
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
SQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHEEE
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ADVAGVAVNSLADIADANEDTARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISRLTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRNRQMEREAEENRRATEAQRRA
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLDLAARFETAVGGIIGQVASSSGVLFQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINT
EEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASQTNLLALNATIEAARAGDAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQE
HHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNVDQAATGTNSVTGHIADVART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AQETGAAAHEVLSASSALSDQAKQLEVEMRRFLNTIRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]