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The map label for this gene is lysR [H]

Identifier: 158425395

GI number: 158425395

Start: 4325280

End: 4326296

Strand: Direct

Name: lysR [H]

Synonym: AZC_3771

Alternate gene names: 158425395

Gene position: 4325280-4326296 (Clockwise)

Preceding gene: 158425392

Following gene: 158425396

Centisome position: 80.55

GC content: 68.83

Gene sequence:

>1017_bases
ATGCTGAATATGGATTTTAATGATCTGGATCTCCGGCAGCTGGATGCCTTCTCCGCCGTCATGTCGGCGGGCAGCATCAC
CGGGGCGGCGCGCCTGCTCGGCCGCTCGCAGCCGGCCACCACGCGCCTCATCCAGGATCTGGAAGAAAGCCTCGGCTATC
CCCTCTTCCACCGCAACGGCCCGCGCATCTCGCCCACCGAGCAGGGTGTCCTCTTCTTCGAGGAGGTGGAACGCCTTCTC
GTCAGCCTGAAGCATATTCGCGAGCGGGCCGGCGCCATCGGGCGCGGCGAGGCCCGCCCGTTCGAGGTAGCCGCAACGCC
CGCACTCTCCATAGGGCTCGTGCCTGATGCGCTGGCGGCCATGGGGGGCACCACACTGCCCCGCCTCCTGCACATCCAGT
CCCTCTCCGCCGAGAACGTGGTGCAGACCCTGCTCGCCCGTGCGGCGGACTTCGGCATCGCAAGCCTGCCCGTCGAGCAT
CCCGGCCTCGACGTGCACTGGATCGGCGAAGCGCCATGCGTGGCGGCGGTGGCGTCCGACTCCGAGCTGGCCACGCAGGA
CACGATCCGCATCGCCGATCTCGCCGGCGCCTGCATCATAACCATGGCGAACCCCTACCGTCTTCGGCGGCGGGTGAATG
AGGCTATCGCGCAGGCGGGCGTCACGCCGCTGCGCGTCATCGATACCAATGCTTCGCTCACCGCATTGTCGCTCGCCCGC
GCGGGGCTGGGCGTTGCCATCGTCGAGCCGGCGAGCGCCTGCGGACTGCTGCCCGAGGGCCTCGTTCTGAAGCCCCTCGA
CGTGCACATTCCTTTCCTCTTCGGCACGGTCTCCCCGGCGGCCAAGCCGTTGTCCTCCACCCTCATCGCCTTCAACGACG
CCTTGCGCGAGGTGGCCGCCCGCCGCCTTCCCGGCTTCCGCCTGCACGAGGCGGGCAAGCGGGAAGCGCTGGCCGATGCG
GTCTATGGCGCGGACGATGCCGCCCCGACCGCCGCCAAAGGGAGACCCATCCGATGA

Upstream 100 bases:

>100_bases
TTATTATGTGCAATCCGTATGGCGCCTGCGCGCTCCGCAGGCGCCATCGGGTGCTCGGTGCCATATTTTCATGCTTGCGA
CGAATTGTACCAGCCTTATC

Downstream 100 bases:

>100_bases
CCGAACGCACGGCCGGCGAACGCCCCATGGACCTTGATGCCCTCGAAGCCCGCCTGAAGCAGGATCTGCAATGGCTGGAA
CTGCCGTCGAAGTCCTGGGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLNMDFNDLDLRQLDAFSAVMSAGSITGAARLLGRSQPATTRLIQDLEESLGYPLFHRNGPRISPTEQGVLFFEEVERLL
VSLKHIRERAGAIGRGEARPFEVAATPALSIGLVPDALAAMGGTTLPRLLHIQSLSAENVVQTLLARAADFGIASLPVEH
PGLDVHWIGEAPCVAAVASDSELATQDTIRIADLAGACIITMANPYRLRRRVNEAIAQAGVTPLRVIDTNASLTALSLAR
AGLGVAIVEPASACGLLPEGLVLKPLDVHIPFLFGTVSPAAKPLSSTLIAFNDALREVAARRLPGFRLHEAGKREALADA
VYGADDAAPTAAKGRPIR

Sequences:

>Translated_338_residues
MLNMDFNDLDLRQLDAFSAVMSAGSITGAARLLGRSQPATTRLIQDLEESLGYPLFHRNGPRISPTEQGVLFFEEVERLL
VSLKHIRERAGAIGRGEARPFEVAATPALSIGLVPDALAAMGGTTLPRLLHIQSLSAENVVQTLLARAADFGIASLPVEH
PGLDVHWIGEAPCVAAVASDSELATQDTIRIADLAGACIITMANPYRLRRRVNEAIAQAGVTPLRVIDTNASLTALSLAR
AGLGVAIVEPASACGLLPEGLVLKPLDVHIPFLFGTVSPAAKPLSSTLIAFNDALREVAARRLPGFRLHEAGKREALADA
VYGADDAAPTAAKGRPIR
>Mature_338_residues
MLNMDFNDLDLRQLDAFSAVMSAGSITGAARLLGRSQPATTRLIQDLEESLGYPLFHRNGPRISPTEQGVLFFEEVERLL
VSLKHIRERAGAIGRGEARPFEVAATPALSIGLVPDALAAMGGTTLPRLLHIQSLSAENVVQTLLARAADFGIASLPVEH
PGLDVHWIGEAPCVAAVASDSELATQDTIRIADLAGACIITMANPYRLRRRVNEAIAQAGVTPLRVIDTNASLTALSLAR
AGLGVAIVEPASACGLLPEGLVLKPLDVHIPFLFGTVSPAAKPLSSTLIAFNDALREVAARRLPGFRLHEAGKREALADA
VYGADDAAPTAAKGRPIR

Specific function: Positive regulatory protein for the noc operon involved in nopaline catabolism and uptake [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789204, Length=312, Percent_Identity=25.6410256410256, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI157672245, Length=232, Percent_Identity=29.3103448275862, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367136, Length=294, Percent_Identity=26.8707482993197, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=265, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693105, Length=241, Percent_Identity=25.3112033195021, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35699; Mature: 35699

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNMDFNDLDLRQLDAFSAVMSAGSITGAARLLGRSQPATTRLIQDLEESLGYPLFHRNG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCC
PRISPTEQGVLFFEEVERLLVSLKHIRERAGAIGRGEARPFEVAATPALSIGLVPDALAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEECCCHHHHHH
MGGTTLPRLLHIQSLSAENVVQTLLARAADFGIASLPVEHPGLDVHWIGEAPCVAAVASD
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCEEEEECCC
SELATQDTIRIADLAGACIITMANPYRLRRRVNEAIAQAGVTPLRVIDTNASLTALSLAR
CHHHHHHHEEHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
AGLGVAIVEPASACGLLPEGLVLKPLDVHIPFLFGTVSPAAKPLSSTLIAFNDALREVAA
CCCCEEEECCHHHHCCCCCCCEECCHHEECCHHEECCCHHHHHHHHHHHHHHHHHHHHHH
RRLPGFRLHEAGKREALADAVYGADDAAPTAAKGRPIR
HHCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNMDFNDLDLRQLDAFSAVMSAGSITGAARLLGRSQPATTRLIQDLEESLGYPLFHRNG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCC
PRISPTEQGVLFFEEVERLLVSLKHIRERAGAIGRGEARPFEVAATPALSIGLVPDALAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEECCCHHHHHH
MGGTTLPRLLHIQSLSAENVVQTLLARAADFGIASLPVEHPGLDVHWIGEAPCVAAVASD
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCEEEEECCC
SELATQDTIRIADLAGACIITMANPYRLRRRVNEAIAQAGVTPLRVIDTNASLTALSLAR
CHHHHHHHEEHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
AGLGVAIVEPASACGLLPEGLVLKPLDVHIPFLFGTVSPAAKPLSSTLIAFNDALREVAA
CCCCEEEECCHHHHCCCCCCCEECCHHEECCHHEECCCHHHHHHHHHHHHHHHHHHHHHH
RRLPGFRLHEAGKREALADAVYGADDAAPTAAKGRPIR
HHCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1799698; 11743193; 11743194 [H]