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The map label for this gene is tsr [C]

Identifier: 158425338

GI number: 158425338

Start: 4260570

End: 4262669

Strand: Direct

Name: tsr [C]

Synonym: AZC_3714

Alternate gene names: 158425338

Gene position: 4260570-4262669 (Clockwise)

Preceding gene: 158425337

Following gene: 158425346

Centisome position: 79.34

GC content: 68.57

Gene sequence:

>2100_bases
ATGCGTTTGACCATCAAGACCACGCTGATCAGCCTGTTCTGCCTCATCAGCCTGATCGTCGCGATCCTCTGTGCGGTAGC
CTTGCGCACCGCCTACAAGGCCTACGTCTCTGCCGGTCAGGCGACGACACTCGCGCATATCGACCGCAATCTCTACGACG
GGCTGGCGAATTTCCGCTTCGAGCGCGGCGAGGCGGGCATCGCCCTCGCACTCGCCAGCGACAAGAACCAGCGCAATGTC
GCCAACATCGCGAGCCGCCGCGAGAAGGTGACCCCCGCGCTTGAGGCCGCGCTCGTCGCCTTCAGGACCTACCCTTTCAT
GGATGCCAAGATGGCGGCGCTGATCAAGGATCTGCAAGGCCAGTTCGAAACCGTGAAGGGCCTGCGCCGCCAGGTGGATG
ACCAGCTCGCGCTGGCGCCGGAGCGCCGGGATGGCTCGGTGGGCCAGCGGTTCGCCGCCGACGGCGGCAAGCTGCTGGAT
ACGCTGGAGCGCCTGTCCACGGAAGTGGAGGCCGACATCCGCTCGCTCGATCCCACGCTGTCGCAGCTCATCCTCGCCCG
CGCCATGGGCTGGGCCACGCGCACCTATACCGGCATCTCCACGCTGCTCATCAATGCCGCCGTCGCGCAGGACCGCCCCC
TCACCGCCGAGGAGACGAAGTCGCTCTTCGCCAATGACGCCAAGGCGGATGTGGCCTGGGGCGCGGTGGTCGAGATCGCC
ATGGCCGACAATGCACCGCCCGCTCTGCGCAAGGCTGCCCAGACCGCGCAGGACTTCTATTTCGCGGGCACGTTCAAGAC
GCTGCGCGACGGCATCGTCAACCGCATCACCCGTGGCGAGAAGAGCGGCGTCTCCCTGCCGGACTGGCGCCAGCCCATCG
AGATCGGTCTCGCCAACTTCGCCGATGTGGCGGGCGTCGCCGTGAACAGCCTCGCCGATATCGCCGACGCCAATGAGGAC
ACAGCCCGCACGACGGCCCTCATCTATGCCGTCGTGCTGCTCGTTTCCCTTGCCCTCGCCGGCGCGGGCCTCGCGGTGGT
CGTCGGCCGCGTGGTGCGGCCCATCTCGCACCTCACCGCCGTGATGGAGGACGTCGCCGGCGGGCATCTGGAGGTCGAGG
TACCGGGCACGGCCCGCCACGACGAGATCGGCGCCATGGCCAAGACGCTCCTCATCTTCAAGGAGAGCCTGCTGCGCAAC
CGGCAGATGGAGCGCGAGGCGGAGGAAAACCGTCGCGCCACGGAGGCCCAGCGCCGCGCCGCCATGCTGGACCTCGCCGC
CCGCTTCGAGACCGCCGTGGGCGGCATCATCGGTCAGGTGGCCAGTTCGTCCGGCGTCCTGCTCCAGACCGCCCAGTCCA
TGAGCCGGGCGGCGGAGCAGACCTCCACGCGCTCGACGGCCGTGGCCGCGGCGGCGGAGGAGGCCTCCACCAACGTGATC
ATGGTCGCTTCTTCGGCGGAGGAGCTGGGTGCCTCGGTGGAGGAGATTTCCCGCCAGGTGATGCAGTCCTCGCAGATGTC
CTCGAGCGCCGTGGCCGAGGCGGACCGGACCGGCGCGGTGATGCGCGAGCTCGCCCAGGCCGCGGCCCGCATCGGCGCGG
TGGTGGAGCTCATCAACACCATCGCCTCCCAGACCAACCTTCTGGCGCTGAACGCGACCATCGAGGCCGCCCGCGCCGGA
GACGCCGGCAAGGGCTTCGCCGTGGTGGCCTCCGAAGTGAAGGAACTGGCCAACCAGACCGGCAAGGCGACGGAAGAGAT
TGCCGCGCAGGTGAATGCCATCCAGTCCACCACGCAAGAGGCGGTGAAGGTCATCGAGAGCGTGGGCCAGCAGATCCGCA
GCATGAGCGACGTGGCCACCGGCATTTCGGCCGCCGTGGAGGAACAGGGCATCGCCACGCGGGAGATCGTCCGCAATGTG
GATCAGGCGGCCACCGGCACCAATTCCGTGACCGGCCACATCACCGACGTCGCCCGCACGGCGCAGGAGACCGGGGCCGC
GGCCCACGAGGTGCTCAGCGCCTCCTCGGCCCTCAGCGATCAGGCCAAGCAGTTGGAGGTGGAAATGCGCCGCTTCCTTG
AGACGGTCCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
CAGACAAGCAATCACGTGCGCGTGAGACCCTGATCGACTCTAGGTTGAGGCAAGCTTAAACACCCCCCAGTGGAACCAAT
TCCTTCCGCTGGAGCGCATC

Downstream 100 bases:

>100_bases
GGTCTCCAAACGCAGACGGCCGGGCGTGGGCCCGGCCGTCTGTCTTTAGATCCTGAAGCGGCCCGGCGTCGGGAACGTCA
GCGGCGGACCACCGCCGGAA

Product: histidine kinase

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MRLTIKTTLISLFCLISLIVAILCAVALRTAYKAYVSAGQATTLAHIDRNLYDGLANFRFERGEAGIALALASDKNQRNV
ANIASRREKVTPALEAALVAFRTYPFMDAKMAALIKDLQGQFETVKGLRRQVDDQLALAPERRDGSVGQRFAADGGKLLD
TLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANED
TARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISHLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRN
RQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLLQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAG
DAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNV
DQAATGTNSVTGHITDVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLETVRAA

Sequences:

>Translated_699_residues
MRLTIKTTLISLFCLISLIVAILCAVALRTAYKAYVSAGQATTLAHIDRNLYDGLANFRFERGEAGIALALASDKNQRNV
ANIASRREKVTPALEAALVAFRTYPFMDAKMAALIKDLQGQFETVKGLRRQVDDQLALAPERRDGSVGQRFAADGGKLLD
TLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANED
TARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISHLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRN
RQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLLQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAG
DAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNV
DQAATGTNSVTGHITDVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLETVRAA
>Mature_699_residues
MRLTIKTTLISLFCLISLIVAILCAVALRTAYKAYVSAGQATTLAHIDRNLYDGLANFRFERGEAGIALALASDKNQRNV
ANIASRREKVTPALEAALVAFRTYPFMDAKMAALIKDLQGQFETVKGLRRQVDDQLALAPERRDGSVGQRFAADGGKLLD
TLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANED
TARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISHLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRN
RQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLLQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAG
DAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNV
DQAATGTNSVTGHITDVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLETVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=342, Percent_Identity=27.4853801169591, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788195, Length=190, Percent_Identity=35.7894736842105, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787690, Length=342, Percent_Identity=25.7309941520468, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789453, Length=179, Percent_Identity=34.6368715083799, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788194, Length=220, Percent_Identity=29.0909090909091, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73913; Mature: 73913

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTIKTTLISLFCLISLIVAILCAVALRTAYKAYVSAGQATTLAHIDRNLYDGLANFRF
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCE
ERGEAGIALALASDKNQRNVANIASRREKVTPALEAALVAFRTYPFMDAKMAALIKDLQG
ECCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QFETVKGLRRQVDDQLALAPERRDGSVGQRFAADGGKLLDTLERLSTEVEADIRSLDPTL
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
SQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHEEE
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ADVAGVAVNSLADIADANEDTARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISHLTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRNRQMEREAEENRRATEAQRRA
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLDLAARFETAVGGIIGQVASSSGVLLQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINT
EEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASQTNLLALNATIEAARAGDAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQE
HHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNVDQAATGTNSVTGHITDVART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AQETGAAAHEVLSASSALSDQAKQLEVEMRRFLETVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLTIKTTLISLFCLISLIVAILCAVALRTAYKAYVSAGQATTLAHIDRNLYDGLANFRF
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCE
ERGEAGIALALASDKNQRNVANIASRREKVTPALEAALVAFRTYPFMDAKMAALIKDLQG
ECCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QFETVKGLRRQVDDQLALAPERRDGSVGQRFAADGGKLLDTLERLSTEVEADIRSLDPTL
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
SQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHEEE
MADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ADVAGVAVNSLADIADANEDTARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISHLTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRNRQMEREAEENRRATEAQRRA
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLDLAARFETAVGGIIGQVASSSGVLLQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINT
EEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASQTNLLALNATIEAARAGDAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQE
HHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNVDQAATGTNSVTGHITDVART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AQETGAAAHEVLSASSALSDQAKQLEVEMRRFLETVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]