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The map label for this gene is argK [C]

Identifier: 158425278

GI number: 158425278

Start: 4196287

End: 4197222

Strand: Direct

Name: argK [C]

Synonym: AZC_3654

Alternate gene names: 158425278

Gene position: 4196287-4197222 (Clockwise)

Preceding gene: 158425277

Following gene: 158425279

Centisome position: 78.15

GC content: 72.76

Gene sequence:

>936_bases
ATGACGCGCACCCGCTTTGCACTGCCCTCCCTTGATGACCTCACCACCGGCGGCAAGCGTGCCGTCGCCGCAGCGCTCGC
GGGCGTCGAGACGGCGCGCGGCACACCCGCCCTCACCGCCTTGCTCGATGCCGCTGCCGCCAACGCCCGCGCGCAGGTTC
TCGGGCTCACCGGCCCGCCGGGGGTCGGCAAGTCCACCCTGACGAACGTGCTCGTGCAGCGCGCCCGCGTCGCGGGCCGC
ACCGTGGCGGTGCTGGCGGTGGACCCCTCCTCCCGGCGCACCGGCGGCGCCCTGCTGGGCGACCGCGCGCGCATCCAGAC
CGATCCGGAGGACCGGGGCGTGTTCGTGCGCTCCATGGCGGCGCGGGACCGGCTGGGCGGCCTCTCGGACGATGCGGTGG
CCGCCGCCGTGCTGCTGCGCGCGGTCTATGATCTCGTGATCGTGGAGACAGTCGGCGTCGGCCAGTCGGAAGCGGACATC
GACCTCATCGCGGATACGGTGGTGCTGTGCATCCAGCCCGCCTCCGGCGACAGCCTCCAGTTCATGAAGGCGGGCGTCAT
GGAACTGCCCGACGTCATCGTGGTGACCAAGGCCGACATGGCCGAGATGTCCCGCCGCGCAGCCGCCGACGTGAGCGGCG
CGCTGGCGCTTGCAGGCGAAGACGGCGCCTGGCGCGTGCCGGTGATTCGCCTCTCCGCCGCGACGGGGGAAGGCATCGAC
GCCTTTGCCGAGGCCGTCGCCAACCACCGCGCCTTCCTCGACGCGGACGATCGCCTCTCCGACCGGCGGTCCACGCAGGA
AAAGCGCTGGGTCGAGGAGGCGGTCAAGGTGCGGTTCGGCACCGACGGGCTGCGCCGAGCCCGGGCGCTCGCCGTGCCCG
AGAGCGGTCCCTTCACCCGAGAGGCCTTTCTCGCGACATGCTTAACCGGCGGGTAA

Upstream 100 bases:

>100_bases
ACGCGCTCCGGAGCCGGATCCGTCTCGTTTTCAGGAGTTGGAGGGCGATTCACTGCTCAGATTGATGCAATCCGAGCGGA
TCGCGCTCTAGAGTGCGGCC

Downstream 100 bases:

>100_bases
GGTTGATAAATCATTCTAGCCGCGTGTCCGGCGCTGCGCCGGGTGCGCGGGTGCGTTCCTGCCCGCCGGTCCCGCCGGCA
GGCCCGTGGAGCCCCGCCTG

Product: periplasmic protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTRTRFALPSLDDLTTGGKRAVAAALAGVETARGTPALTALLDAAAANARAQVLGLTGPPGVGKSTLTNVLVQRARVAGR
TVAVLAVDPSSRRTGGALLGDRARIQTDPEDRGVFVRSMAARDRLGGLSDDAVAAAVLLRAVYDLVIVETVGVGQSEADI
DLIADTVVLCIQPASGDSLQFMKAGVMELPDVIVVTKADMAEMSRRAAADVSGALALAGEDGAWRVPVIRLSAATGEGID
AFAEAVANHRAFLDADDRLSDRRSTQEKRWVEEAVKVRFGTDGLRRARALAVPESGPFTREAFLATCLTGG

Sequences:

>Translated_311_residues
MTRTRFALPSLDDLTTGGKRAVAAALAGVETARGTPALTALLDAAAANARAQVLGLTGPPGVGKSTLTNVLVQRARVAGR
TVAVLAVDPSSRRTGGALLGDRARIQTDPEDRGVFVRSMAARDRLGGLSDDAVAAAVLLRAVYDLVIVETVGVGQSEADI
DLIADTVVLCIQPASGDSLQFMKAGVMELPDVIVVTKADMAEMSRRAAADVSGALALAGEDGAWRVPVIRLSAATGEGID
AFAEAVANHRAFLDADDRLSDRRSTQEKRWVEEAVKVRFGTDGLRRARALAVPESGPFTREAFLATCLTGG
>Mature_310_residues
TRTRFALPSLDDLTTGGKRAVAAALAGVETARGTPALTALLDAAAANARAQVLGLTGPPGVGKSTLTNVLVQRARVAGRT
VAVLAVDPSSRRTGGALLGDRARIQTDPEDRGVFVRSMAARDRLGGLSDDAVAAAVLLRAVYDLVIVETVGVGQSEADID
LIADTVVLCIQPASGDSLQFMKAGVMELPDVIVVTKADMAEMSRRAAADVSGALALAGEDGAWRVPVIRLSAATGEGIDA
FAEAVANHRAFLDADDRLSDRRSTQEKRWVEEAVKVRFGTDGLRRARALAVPESGPFTREAFLATCLTGG

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=297, Percent_Identity=35.3535353535354, Blast_Score=151, Evalue=8e-37,
Organism=Escherichia coli, GI1789285, Length=289, Percent_Identity=34.6020761245675, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71994271, Length=284, Percent_Identity=32.3943661971831, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71994275, Length=228, Percent_Identity=35.0877192982456, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 32357; Mature: 32226

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTRFALPSLDDLTTGGKRAVAAALAGVETARGTPALTALLDAAAANARAQVLGLTGPP
CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCC
GVGKSTLTNVLVQRARVAGRTVAVLAVDPSSRRTGGALLGDRARIQTDPEDRGVFVRSMA
CCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHH
ARDRLGGLSDDAVAAAVLLRAVYDLVIVETVGVGQSEADIDLIADTVVLCIQPASGDSLQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEEECCCCCCHH
FMKAGVMELPDVIVVTKADMAEMSRRAAADVSGALALAGEDGAWRVPVIRLSAATGEGID
HHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEECCCCCCHH
AFAEAVANHRAFLDADDRLSDRRSTQEKRWVEEAVKVRFGTDGLRRARALAVPESGPFTR
HHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCHH
EAFLATCLTGG
HHHHHHHHCCC
>Mature Secondary Structure 
TRTRFALPSLDDLTTGGKRAVAAALAGVETARGTPALTALLDAAAANARAQVLGLTGPP
CCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCC
GVGKSTLTNVLVQRARVAGRTVAVLAVDPSSRRTGGALLGDRARIQTDPEDRGVFVRSMA
CCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHH
ARDRLGGLSDDAVAAAVLLRAVYDLVIVETVGVGQSEADIDLIADTVVLCIQPASGDSLQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEEECCCCCCHH
FMKAGVMELPDVIVVTKADMAEMSRRAAADVSGALALAGEDGAWRVPVIRLSAATGEGID
HHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEECCCCCCHH
AFAEAVANHRAFLDADDRLSDRRSTQEKRWVEEAVKVRFGTDGLRRARALAVPESGPFTR
HHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCHH
EAFLATCLTGG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]