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The map label for this gene is pdtaS [H]

Identifier: 158425275

GI number: 158425275

Start: 4193999

End: 4195081

Strand: Direct

Name: pdtaS [H]

Synonym: AZC_3651

Alternate gene names: 158425275

Gene position: 4193999-4195081 (Clockwise)

Preceding gene: 158425274

Following gene: 158425277

Centisome position: 78.1

GC content: 69.25

Gene sequence:

>1083_bases
ATGGCGGGGGCGACCGAGATCCGGATGCTCTATATTGACGATGATCCGGGGCTCGCGCGTCTTGTGCAGCGCCAGCTCGG
TCGCCGCGGCTATGCGGTGGAGACCGCCGCCTCAGGGGTGGAAGGGCTGGAGCGTATCCGCGCCGGCGGCATCGACGTGG
TGGCGCTCGACCATTACATGCCCGGCCAGGACGGGCTCCAGACGCTGGAGGCCATCCGCGCCCTGCCCGCCCCGCCGCCC
GTGGTCTATGTCACCGGCACACAGGAAAGCCGCGTCGCCGTCGCGGCCCTGAAGGCCGGGGCGGCGGACTATGTGGTCAA
GGAAGTCCAGGGCGACTTCATCGAACTCCTCACCTCCGCCATCAACGCCGCCCTTGAACAGGTGAAGATGCGCCGCGCCC
ACGAGGCGGCGGAGGCCGAGATCCGCGCCGCCCGCGACCGCTTCGAGGCGCTGGCGGCCGAACGGGCGATGCTGCTGCGG
GAGATGAACCACCGCGTCGGCAATTCGTTGCAGATCATCATGTCGCTGCTGCACCTCCAGGCGGGCGCCACCGACAATGA
GGAGGTGCAGACGGCGCTCAGCAACGCGCGCGGGCGCGTCGCCGCCGTCGCGCAGGTGCACCGCCGGCTCTATACGTCCG
AGCAGGTGGGCAGCGTGTCGGTGGACCAGTATCTGGGCGCGCTGCTGGATGACCTCCAGATCTCCGCCCAGCATGGCGAT
GTGGGCATCACCATCGACACCGACATCGCACCGCTGGAGATCGATCCGGATCGGGCAGTGGCGCTCGGCGTGGTGGTCAC
CGAACTCGTCATCAACGCCTCGAAATATGCCTATCCCGGCAGCAAGGGGCCGGTGCGCGTCACGCTGGCGGTGGACGGGC
CGCAGGCGCGTCTCAGTGTCGAGGACGACGGCATCGGTCTCGGCGGCGAGACGGCGGCCAAGGGCAACGGCCTTGGCAAC
CGCATCGTCACCGCCATGGCCTCCAAGCTGGGGGCGTCGCTGGCCTTCCTGCCGAAGGACAAGGGCACGTCCGTGCGCAT
GGAGTTTCCGCTCCAGCCGCAGGACGGCCGGAGCGCCCACTGA

Upstream 100 bases:

>100_bases
TCTCCAATGCCGTGCGTCAGCTCGGCCTGTTCTTCTCGGTCATCCAGGTGCCAGAGGCAAAGTAATGGGCGAAGCGGCGC
GCAAGGACGCCCCCCCGGAC

Downstream 100 bases:

>100_bases
TAAACGGCGCTGGCCGCTCAGCCGACGTCGGTGGGGAAGCCCGCTTCCTTCCAGCCGAGAATGCCGCCCTGCATATGCTC
CTCATAGGGCAGGCCCGCCG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MAGATEIRMLYIDDDPGLARLVQRQLGRRGYAVETAASGVEGLERIRAGGIDVVALDHYMPGQDGLQTLEAIRALPAPPP
VVYVTGTQESRVAVAALKAGAADYVVKEVQGDFIELLTSAINAALEQVKMRRAHEAAEAEIRAARDRFEALAAERAMLLR
EMNHRVGNSLQIIMSLLHLQAGATDNEEVQTALSNARGRVAAVAQVHRRLYTSEQVGSVSVDQYLGALLDDLQISAQHGD
VGITIDTDIAPLEIDPDRAVALGVVVTELVINASKYAYPGSKGPVRVTLAVDGPQARLSVEDDGIGLGGETAAKGNGLGN
RIVTAMASKLGASLAFLPKDKGTSVRMEFPLQPQDGRSAH

Sequences:

>Translated_360_residues
MAGATEIRMLYIDDDPGLARLVQRQLGRRGYAVETAASGVEGLERIRAGGIDVVALDHYMPGQDGLQTLEAIRALPAPPP
VVYVTGTQESRVAVAALKAGAADYVVKEVQGDFIELLTSAINAALEQVKMRRAHEAAEAEIRAARDRFEALAAERAMLLR
EMNHRVGNSLQIIMSLLHLQAGATDNEEVQTALSNARGRVAAVAQVHRRLYTSEQVGSVSVDQYLGALLDDLQISAQHGD
VGITIDTDIAPLEIDPDRAVALGVVVTELVINASKYAYPGSKGPVRVTLAVDGPQARLSVEDDGIGLGGETAAKGNGLGN
RIVTAMASKLGASLAFLPKDKGTSVRMEFPLQPQDGRSAH
>Mature_359_residues
AGATEIRMLYIDDDPGLARLVQRQLGRRGYAVETAASGVEGLERIRAGGIDVVALDHYMPGQDGLQTLEAIRALPAPPPV
VYVTGTQESRVAVAALKAGAADYVVKEVQGDFIELLTSAINAALEQVKMRRAHEAAEAEIRAARDRFEALAAERAMLLRE
MNHRVGNSLQIIMSLLHLQAGATDNEEVQTALSNARGRVAAVAQVHRRLYTSEQVGSVSVDQYLGALLDDLQISAQHGDV
GITIDTDIAPLEIDPDRAVALGVVVTELVINASKYAYPGSKGPVRVTLAVDGPQARLSVEDDGIGLGGETAAKGNGLGNR
IVTAMASKLGASLAFLPKDKGTSVRMEFPLQPQDGRSAH

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=109, Percent_Identity=37.6146788990826, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788191, Length=128, Percent_Identity=35.9375, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=30, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38182; Mature: 38051

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGATEIRMLYIDDDPGLARLVQRQLGRRGYAVETAASGVEGLERIRAGGIDVVALDHYM
CCCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEEEECCCC
PGQDGLQTLEAIRALPAPPPVVYVTGTQESRVAVAALKAGAADYVVKEVQGDFIELLTSA
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHH
INAALEQVKMRRAHEAAEAEIRAARDRFEALAAERAMLLREMNHRVGNSLQIIMSLLHLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGATDNEEVQTALSNARGRVAAVAQVHRRLYTSEQVGSVSVDQYLGALLDDLQISAQHGD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCC
VGITIDTDIAPLEIDPDRAVALGVVVTELVINASKYAYPGSKGPVRVTLAVDGPQARLSV
EEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCHHCCCCCCCCCEEEEEEECCCCEEEEE
EDDGIGLGGETAAKGNGLGNRIVTAMASKLGASLAFLPKDKGTSVRMEFPLQPQDGRSAH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AGATEIRMLYIDDDPGLARLVQRQLGRRGYAVETAASGVEGLERIRAGGIDVVALDHYM
CCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEEEECCCC
PGQDGLQTLEAIRALPAPPPVVYVTGTQESRVAVAALKAGAADYVVKEVQGDFIELLTSA
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHH
INAALEQVKMRRAHEAAEAEIRAARDRFEALAAERAMLLREMNHRVGNSLQIIMSLLHLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGATDNEEVQTALSNARGRVAAVAQVHRRLYTSEQVGSVSVDQYLGALLDDLQISAQHGD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCC
VGITIDTDIAPLEIDPDRAVALGVVVTELVINASKYAYPGSKGPVRVTLAVDGPQARLSV
EEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCHHCCCCCCCCCEEEEEEECCCCEEEEE
EDDGIGLGGETAAKGNGLGNRIVTAMASKLGASLAFLPKDKGTSVRMEFPLQPQDGRSAH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]