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The map label for this gene is aphA [H]

Identifier: 158425273

GI number: 158425273

Start: 4192028

End: 4193533

Strand: Direct

Name: aphA [H]

Synonym: AZC_3649

Alternate gene names: 158425273

Gene position: 4192028-4193533 (Clockwise)

Preceding gene: 158425270

Following gene: 158425274

Centisome position: 78.07

GC content: 66.73

Gene sequence:

>1506_bases
GTGAGCACACCCACCCTCCCCGCTCGGTCCGGCCGCCAGGTGCTCCTCCAAGCCACCATGATGGGCTGTGGCCTGGCCGT
GCTCGTCGTGATCAGCGTCGCGTCGCTCTTCCTCATCAACCGCACACGCGAGGACGCGAACCAGGTCACCCAGACCCTGC
TCATGGAGAATGACCTTTCCACCCTGCGCAACCAGGTGCTGCGCGCGGAAAGCTCCCAGCGCGGCTTCCTGCTGACGGGC
GACACCGATTATCTGGGCGCCTTCGATTCGTCGGTCGCCGAAATGGGGCCGCTCCTCGACCAGATCAGAGAGCGCCTGCG
GGGCGACACGCGCCGCCTCGCCGCGGCTGAGCAACTCACCGATCTGGTGCGCGCCAAGCAGGATGAACTGCGCCACACCG
TGCTTCTCAAGCGGTCCGGAAACGACACCGGCGCCCTCGCCGTGGTGCGCACCGATCGCGGCGAGCGACTGACGCGCGAC
ATCAGCGCCATCATCGCCACCATGCAGAAGACCGAGCAGGCGCTGCTGGCGGAGCGCTCGGAGACCTCCAGCCGCTCCAG
CTTCCTGCTGCTGATCGTCAACCTCGTGGGCGTCGCTGCCCTCATCATCATCGCCGTCATCGGCCTGCGGCTCGCCCAGA
AGACCGCCGACGCCCTGCGGCGCGCCCATCACGAGGTGGAAGGCGCCAACCAGATCCTCGAGCAGCGGGTGGCCGAGCGC
ACCGCCGACCTCCAGGAAGCCAATAACGAGATCCAGAGCTTCGCCTACATCGTCAGCCATGACCTGCGCGCGCCGCTGGT
CAACATCATGGGCTTCACCAGCGAACTGGAAGCGCTGCGCACCGACCTGTTCGACCGTCTTGCCGACCTGCGCCGCCGCG
TGGGCGAGGAGGCCTCCGACTCGGACGAGGACCTCGACAAGGACTTCAGCGAGGCCTTCGGCTTCATCAAGGCGTCCATC
ACCAAGATGGACCGCCTCATCAACGCCATCCTCGATCTCTCTCGCCAGGGGCGGAAGGAATTCGCCCCCGCCGCCATCAA
CGTCACCGAGCTGATGCAGGCCATCACCGCCACCATGGCGCACCAGCTGATGGACCGCGAAGCCAAGGTCAGCATCACGC
CCCTGCCCTCGATCATCTCCGACCGGCTCGCCCTCGAACAGGTGTTCACGAACCTGATCGACAATGCGGTGAAGTACCTG
CGCCCGGAAGTCCCCGGCCTGATCGAGATCTCGGCGCGCGAGACGCCCGGCTACATCACCTACATGATCCGCGACAACGG
CCGCGGCATCGATCCCAACGACCGCGCGCGGGTGTTCGAGCTGTTCCGGCGCTCGGGTCCGCAGGACCGGCCGGGGGAAG
GCATCGGGCTCGCCCATGTGCGGGCCCTCGTCCGGCGCCTTGGGGGAGGCATCACGCTGGACTCGGAACTGGGGCAAGGC
ACCGTCTTCAAGGTGACGCTGCCCCGCAAGCTCGTTGTCGACACTCATGGGGGAAAGAATGCCTGA

Upstream 100 bases:

>100_bases
GCAGGCATGCGCCCCTGCGCGCTTTTGTCATGCGCGGATGGGCGCATCGTCGGGCCTGCGGCCTTGAAAGGCAAGGGCCG
GCTGTGGACCGGAGCCGCCC

Downstream 100 bases:

>100_bases
GCATGTGACCATCGTCATGATCGAGGACGATCCGGGCCACGCGCGGCTGATCGAGAAGAACATCCGCCGCGCCGGCGTGC
TCAACGAGATCATGCCCTTC

Product: histidine kinase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSTPTLPARSGRQVLLQATMMGCGLAVLVVISVASLFLINRTREDANQVTQTLLMENDLSTLRNQVLRAESSQRGFLLTG
DTDYLGAFDSSVAEMGPLLDQIRERLRGDTRRLAAAEQLTDLVRAKQDELRHTVLLKRSGNDTGALAVVRTDRGERLTRD
ISAIIATMQKTEQALLAERSETSSRSSFLLLIVNLVGVAALIIIAVIGLRLAQKTADALRRAHHEVEGANQILEQRVAER
TADLQEANNEIQSFAYIVSHDLRAPLVNIMGFTSELEALRTDLFDRLADLRRRVGEEASDSDEDLDKDFSEAFGFIKASI
TKMDRLINAILDLSRQGRKEFAPAAINVTELMQAITATMAHQLMDREAKVSITPLPSIISDRLALEQVFTNLIDNAVKYL
RPEVPGLIEISARETPGYITYMIRDNGRGIDPNDRARVFELFRRSGPQDRPGEGIGLAHVRALVRRLGGGITLDSELGQG
TVFKVTLPRKLVVDTHGGKNA

Sequences:

>Translated_501_residues
MSTPTLPARSGRQVLLQATMMGCGLAVLVVISVASLFLINRTREDANQVTQTLLMENDLSTLRNQVLRAESSQRGFLLTG
DTDYLGAFDSSVAEMGPLLDQIRERLRGDTRRLAAAEQLTDLVRAKQDELRHTVLLKRSGNDTGALAVVRTDRGERLTRD
ISAIIATMQKTEQALLAERSETSSRSSFLLLIVNLVGVAALIIIAVIGLRLAQKTADALRRAHHEVEGANQILEQRVAER
TADLQEANNEIQSFAYIVSHDLRAPLVNIMGFTSELEALRTDLFDRLADLRRRVGEEASDSDEDLDKDFSEAFGFIKASI
TKMDRLINAILDLSRQGRKEFAPAAINVTELMQAITATMAHQLMDREAKVSITPLPSIISDRLALEQVFTNLIDNAVKYL
RPEVPGLIEISARETPGYITYMIRDNGRGIDPNDRARVFELFRRSGPQDRPGEGIGLAHVRALVRRLGGGITLDSELGQG
TVFKVTLPRKLVVDTHGGKNA
>Mature_500_residues
STPTLPARSGRQVLLQATMMGCGLAVLVVISVASLFLINRTREDANQVTQTLLMENDLSTLRNQVLRAESSQRGFLLTGD
TDYLGAFDSSVAEMGPLLDQIRERLRGDTRRLAAAEQLTDLVRAKQDELRHTVLLKRSGNDTGALAVVRTDRGERLTRDI
SAIIATMQKTEQALLAERSETSSRSSFLLLIVNLVGVAALIIIAVIGLRLAQKTADALRRAHHEVEGANQILEQRVAERT
ADLQEANNEIQSFAYIVSHDLRAPLVNIMGFTSELEALRTDLFDRLADLRRRVGEEASDSDEDLDKDFSEAFGFIKASIT
KMDRLINAILDLSRQGRKEFAPAAINVTELMQAITATMAHQLMDREAKVSITPLPSIISDRLALEQVFTNLIDNAVKYLR
PEVPGLIEISARETPGYITYMIRDNGRGIDPNDRARVFELFRRSGPQDRPGEGIGLAHVRALVRRLGGGITLDSELGQGT
VFKVTLPRKLVVDTHGGKNA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=26.0377358490566, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=349, Percent_Identity=27.2206303724928, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=28.6307053941909, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=24.2914979757085, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=392, Percent_Identity=24.4897959183673, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=27.6150627615063, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55253; Mature: 55122

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTLPARSGRQVLLQATMMGCGLAVLVVISVASLFLINRTREDANQVTQTLLMENDLS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRNQVLRAESSQRGFLLTGDTDYLGAFDSSVAEMGPLLDQIRERLRGDTRRLAAAEQLT
HHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DLVRAKQDELRHTVLLKRSGNDTGALAVVRTDRGERLTRDISAIIATMQKTEQALLAERS
HHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ETSSRSSFLLLIVNLVGVAALIIIAVIGLRLAQKTADALRRAHHEVEGANQILEQRVAER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TADLQEANNEIQSFAYIVSHDLRAPLVNIMGFTSELEALRTDLFDRLADLRRRVGEEASD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDEDLDKDFSEAFGFIKASITKMDRLINAILDLSRQGRKEFAPAAINVTELMQAITATMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHH
HQLMDREAKVSITPLPSIISDRLALEQVFTNLIDNAVKYLRPEVPGLIEISARETPGYIT
HHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
YMIRDNGRGIDPNDRARVFELFRRSGPQDRPGEGIGLAHVRALVRRLGGGITLDSELGQG
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCC
TVFKVTLPRKLVVDTHGGKNA
EEEEEECCCEEEEECCCCCCC
>Mature Secondary Structure 
STPTLPARSGRQVLLQATMMGCGLAVLVVISVASLFLINRTREDANQVTQTLLMENDLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRNQVLRAESSQRGFLLTGDTDYLGAFDSSVAEMGPLLDQIRERLRGDTRRLAAAEQLT
HHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DLVRAKQDELRHTVLLKRSGNDTGALAVVRTDRGERLTRDISAIIATMQKTEQALLAERS
HHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ETSSRSSFLLLIVNLVGVAALIIIAVIGLRLAQKTADALRRAHHEVEGANQILEQRVAER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TADLQEANNEIQSFAYIVSHDLRAPLVNIMGFTSELEALRTDLFDRLADLRRRVGEEASD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDEDLDKDFSEAFGFIKASITKMDRLINAILDLSRQGRKEFAPAAINVTELMQAITATMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHH
HQLMDREAKVSITPLPSIISDRLALEQVFTNLIDNAVKYLRPEVPGLIEISARETPGYIT
HHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
YMIRDNGRGIDPNDRARVFELFRRSGPQDRPGEGIGLAHVRALVRRLGGGITLDSELGQG
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCC
TVFKVTLPRKLVVDTHGGKNA
EEEEEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]