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The map label for this gene is oxlT [H]

Identifier: 158425258

GI number: 158425258

Start: 4172256

End: 4173557

Strand: Reverse

Name: oxlT [H]

Synonym: AZC_3634

Alternate gene names: 158425258

Gene position: 4173557-4172256 (Counterclockwise)

Preceding gene: 158425259

Following gene: 158425257

Centisome position: 77.72

GC content: 62.75

Gene sequence:

>1302_bases
ATGGTCGCTCAAGCTGGGAGCAGCCCCGCGCCGTCTACGCGCTGGCTGCAGTTGGTGGCCGGCATCGTCTGCATGGTCGC
GGCTGCCAACATTCAATATTCTTGGACACTCTTCGTTCCGGAGATCCAGAACGCCCACGGCTGGACGCGTGCGTCCATTC
AGGTGGCCTTCACCATCTTCGTCGTGGTGCAGACTTGGCTGACGCCGATCGAGGGCTACTTCATCGACAAGTACGGCCCG
CGCGCCGTGGTGTTCGTGGGTGGTCTCTTCACCGGCCTGTCCTGGATCGTCAACTCCTATGCCACCACGCTGACGGGCTT
CTACGTGGGCGCGGTCATCGGCGGCATCGGCGTCGGCTGCGTGTATGCCACCTGCGTCAACAGCGCGCTGAAGTGGTTCC
CGGACAAGCGCGGTCTTGCGGTCGGTCTCACCGCGGCGGGCTACGGCTCGGGCACGGTTCTGACGATCATGCCGATCGCC
AACATGCTCAAGACCTCCGGCTATCAGGACACCTTCTTCCTGTTCGGCCTCATCCAGGGCGCCATCATCCTTCTCGCGGC
GGGCTTCCTGCGGCAGCCGGGCTCCGGTGAAGTGGTGTATTCGGCGAGCGTCGCCCAGTCCCGGCGTGACTACACGCTCG
GCGAAGCGCTGCGCACTCCGGTCTTCTACGTCATGCTCGGCATGTTCATCTGCACCGTTACCGGCGGTCTGATGGCTGTG
GCGCAGCTCGGCGTCATCGCGGAAGACCTCGGTGTGAAGAAGGTGGAAGTGAACCTCTACTTCTTCGCCATGGCCGCCCT
GCCGTTCGCGCTGATGCTGGACCGTATCCTCAACGGTATTTCGCGTCCGCTGTTCGGCTGGATCTCCGACCATATCGGCC
GTGAGAAGACCATGTTCTTTGCTTTCGCCATGGAAGGCATCGGCATCGTCGCCCTCGGCACGTTCGGTCACAATCCCTGG
GCCTTCATCATCCTGTCCGGCGTGGTCTTCCTCGCCTGGGGTGAAGTCTACTCTCTGTTCAGTGCAACCGCGGCCGATAC
GTTCGGTTCCAAGCATGTGGGCAAGATCTACGGCGTTCTTTACTGCGCCAAGGGTGTTGCGGCTCTGCTTGTTCCCGTGG
CGAACCTGATCATGGAAGCATCGGGCAGCTGGGCGACGGTTCTTTACATCGTCGCGGCCATGGATCTGACCGCTGCCTTT
GCCGCGCTTTTCGTTCTGCGTCCGATGCTGGCGCGCCATCACCGGCAGAACGAAGCGGCGGCCCAAGCCCTGCGCGAGCG
CGACGGTATCGTCCGCGCTTGA

Upstream 100 bases:

>100_bases
CAAGTTCTACGCGTTCGCAACAGCCGCCCAAAGAGGGACAGAGGGTCGGGCGGTCCTCATATCAATAGAAGAAAAATCAT
CTTCATCAGGGGTAGGAAAC

Downstream 100 bases:

>100_bases
ACAAAGAGCCCTCTGTCGCCCTCGGGCGACCCCTCGCGGCCCCGGCTTTGCCGGGGCCTTTTTTTTTTGTTTTCGCGCGC
GATCCGGGCGCTGTTGCCCG

Product: oxalate/formate antiporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MVAQAGSSPAPSTRWLQLVAGIVCMVAAANIQYSWTLFVPEIQNAHGWTRASIQVAFTIFVVVQTWLTPIEGYFIDKYGP
RAVVFVGGLFTGLSWIVNSYATTLTGFYVGAVIGGIGVGCVYATCVNSALKWFPDKRGLAVGLTAAGYGSGTVLTIMPIA
NMLKTSGYQDTFFLFGLIQGAIILLAAGFLRQPGSGEVVYSASVAQSRRDYTLGEALRTPVFYVMLGMFICTVTGGLMAV
AQLGVIAEDLGVKKVEVNLYFFAMAALPFALMLDRILNGISRPLFGWISDHIGREKTMFFAFAMEGIGIVALGTFGHNPW
AFIILSGVVFLAWGEVYSLFSATAADTFGSKHVGKIYGVLYCAKGVAALLVPVANLIMEASGSWATVLYIVAAMDLTAAF
AALFVLRPMLARHHRQNEAAAQALRERDGIVRA

Sequences:

>Translated_433_residues
MVAQAGSSPAPSTRWLQLVAGIVCMVAAANIQYSWTLFVPEIQNAHGWTRASIQVAFTIFVVVQTWLTPIEGYFIDKYGP
RAVVFVGGLFTGLSWIVNSYATTLTGFYVGAVIGGIGVGCVYATCVNSALKWFPDKRGLAVGLTAAGYGSGTVLTIMPIA
NMLKTSGYQDTFFLFGLIQGAIILLAAGFLRQPGSGEVVYSASVAQSRRDYTLGEALRTPVFYVMLGMFICTVTGGLMAV
AQLGVIAEDLGVKKVEVNLYFFAMAALPFALMLDRILNGISRPLFGWISDHIGREKTMFFAFAMEGIGIVALGTFGHNPW
AFIILSGVVFLAWGEVYSLFSATAADTFGSKHVGKIYGVLYCAKGVAALLVPVANLIMEASGSWATVLYIVAAMDLTAAF
AALFVLRPMLARHHRQNEAAAQALRERDGIVRA
>Mature_433_residues
MVAQAGSSPAPSTRWLQLVAGIVCMVAAANIQYSWTLFVPEIQNAHGWTRASIQVAFTIFVVVQTWLTPIEGYFIDKYGP
RAVVFVGGLFTGLSWIVNSYATTLTGFYVGAVIGGIGVGCVYATCVNSALKWFPDKRGLAVGLTAAGYGSGTVLTIMPIA
NMLKTSGYQDTFFLFGLIQGAIILLAAGFLRQPGSGEVVYSASVAQSRRDYTLGEALRTPVFYVMLGMFICTVTGGLMAV
AQLGVIAEDLGVKKVEVNLYFFAMAALPFALMLDRILNGISRPLFGWISDHIGREKTMFFAFAMEGIGIVALGTFGHNPW
AFIILSGVVFLAWGEVYSLFSATAADTFGSKHVGKIYGVLYCAKGVAALLVPVANLIMEASGSWATVLYIVAAMDLTAAF
AALFVLRPMLARHHRQNEAAAQALRERDGIVRA

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=363, Percent_Identity=23.6914600550964, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193209150, Length=368, Percent_Identity=22.8260869565217, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46392; Mature: 46392

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00036 BZIP_BASIC ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQAGSSPAPSTRWLQLVAGIVCMVAAANIQYSWTLFVPEIQNAHGWTRASIQVAFTIF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHH
VVVQTWLTPIEGYFIDKYGPRAVVFVGGLFTGLSWIVNSYATTLTGFYVGAVIGGIGVGC
HHHHHHHHHHCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYATCVNSALKWFPDKRGLAVGLTAAGYGSGTVLTIMPIANMLKTSGYQDTFFLFGLIQG
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHH
AIILLAAGFLRQPGSGEVVYSASVAQSRRDYTLGEALRTPVFYVMLGMFICTVTGGLMAV
HHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLGVIAEDLGVKKVEVNLYFFAMAALPFALMLDRILNGISRPLFGWISDHIGREKTMFF
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AFAMEGIGIVALGTFGHNPWAFIILSGVVFLAWGEVYSLFSATAADTFGSKHVGKIYGVL
EEHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YCAKGVAALLVPVANLIMEASGSWATVLYIVAAMDLTAAFAALFVLRPMLARHHRQNEAA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQALRERDGIVRA
HHHHHHHCCCCCC
>Mature Secondary Structure
MVAQAGSSPAPSTRWLQLVAGIVCMVAAANIQYSWTLFVPEIQNAHGWTRASIQVAFTIF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHH
VVVQTWLTPIEGYFIDKYGPRAVVFVGGLFTGLSWIVNSYATTLTGFYVGAVIGGIGVGC
HHHHHHHHHHCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYATCVNSALKWFPDKRGLAVGLTAAGYGSGTVLTIMPIANMLKTSGYQDTFFLFGLIQG
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHH
AIILLAAGFLRQPGSGEVVYSASVAQSRRDYTLGEALRTPVFYVMLGMFICTVTGGLMAV
HHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLGVIAEDLGVKKVEVNLYFFAMAALPFALMLDRILNGISRPLFGWISDHIGREKTMFF
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AFAMEGIGIVALGTFGHNPWAFIILSGVVFLAWGEVYSLFSATAADTFGSKHVGKIYGVL
EEHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YCAKGVAALLVPVANLIMEASGSWATVLYIVAAMDLTAAFAALFVLRPMLARHHRQNEAA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQALRERDGIVRA
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]