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The map label for this gene is thyX [H]

Identifier: 158425219

GI number: 158425219

Start: 4126678

End: 4127406

Strand: Reverse

Name: thyX [H]

Synonym: AZC_3595

Alternate gene names: 158425219

Gene position: 4127406-4126678 (Counterclockwise)

Preceding gene: 158425220

Following gene: 158425218

Centisome position: 76.86

GC content: 65.43

Gene sequence:

>729_bases
ATGGGTTCGGACCTCACCGTCGTCAACGCGGCGCGGGTGAGCTTCGACAGGGAAAGCGACTGGCTTCACGCCGCAGGTCC
CCGCGAGTTGAGCGGGAAGGACAAGCGCCTCATCCGATTCCTGGCACGAGGTTGCGAGAGCGGCGAGTGGGAAGCCCACA
TCAACGAGCTGTCCGACACCCATGACCCCGCCGAGTGCGGGGAAATCCTGAAGTGGGCGAAGCGCCTTCCCGAGCACTGG
ACCCCCTTCGCCCATACGGCCATCACCCTGCGCGAACACGTTCCGGTGCCTGTGGCCCGCCAGCGGTTCAAGCACAAGGT
CGGCTTCGTGGAGAACGAGGTGTCCCGCCGCTATGTGGACGATGCCCCGACGTTCGCGGAGCTGACGTGGCGCAGGCGGG
CGGCGAACAAGAAGCAGGGCTCGGCCGAGGACTTCGATCCCGTCTCGCAAGCGATGCTCAATGACGAGTATGAGGCGGCG
ACGGCGGACGCCCTGCGGCGCTACCGGCTGTTCCTCGATCACGGCGTCTGTCCTGAACAGGCCCGCTTCCTCCTGCCGCA
GGCGATGATGACGACTTATTGGGCGACGGGGAGCCTCTATGCCTTCGCCCAAGCCTACGTGAAGCGCAGTGACAGCCACG
CCCAAAAGGAAATCCAGCTTCTGGCGGCGGAATGGGACCGGATCATCCGGCCGCTGTTCCCCGTGAGCTGGGCTGCACTG
GTGGACTGA

Upstream 100 bases:

>100_bases
GTCGATGCGACCACCTTCGGCCGCATCTGGCGCGTCACCCCGAAAGGCTTGTCCCTCCTGTTTCAGAGGTGGAATGATCC
GGGTTGATTACATCCAGCAC

Downstream 100 bases:

>100_bases
AACCGTGGAACCTGAAGCCTATCACCACCCCGACATTATCTGTCAGCGGGCCACGGCCCTCGCCGAGTTGGCCGCGACCG
TGGACAACACAAAGAACCGG

Product: alternative thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MGSDLTVVNAARVSFDRESDWLHAAGPRELSGKDKRLIRFLARGCESGEWEAHINELSDTHDPAECGEILKWAKRLPEHW
TPFAHTAITLREHVPVPVARQRFKHKVGFVENEVSRRYVDDAPTFAELTWRRRAANKKQGSAEDFDPVSQAMLNDEYEAA
TADALRRYRLFLDHGVCPEQARFLLPQAMMTTYWATGSLYAFAQAYVKRSDSHAQKEIQLLAAEWDRIIRPLFPVSWAAL
VD

Sequences:

>Translated_242_residues
MGSDLTVVNAARVSFDRESDWLHAAGPRELSGKDKRLIRFLARGCESGEWEAHINELSDTHDPAECGEILKWAKRLPEHW
TPFAHTAITLREHVPVPVARQRFKHKVGFVENEVSRRYVDDAPTFAELTWRRRAANKKQGSAEDFDPVSQAMLNDEYEAA
TADALRRYRLFLDHGVCPEQARFLLPQAMMTTYWATGSLYAFAQAYVKRSDSHAQKEIQLLAAEWDRIIRPLFPVSWAAL
VD
>Mature_241_residues
GSDLTVVNAARVSFDRESDWLHAAGPRELSGKDKRLIRFLARGCESGEWEAHINELSDTHDPAECGEILKWAKRLPEHWT
PFAHTAITLREHVPVPVARQRFKHKVGFVENEVSRRYVDDAPTFAELTWRRRAANKKQGSAEDFDPVSQAMLNDEYEAAT
ADALRRYRLFLDHGVCPEQARFLLPQAMMTTYWATGSLYAFAQAYVKRSDSHAQKEIQLLAAEWDRIIRPLFPVSWAALV
D

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 27692; Mature: 27561

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSDLTVVNAARVSFDRESDWLHAAGPRELSGKDKRLIRFLARGCESGEWEAHINELSDT
CCCCCEEEHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCC
HDPAECGEILKWAKRLPEHWTPFAHTAITLREHVPVPVARQRFKHKVGFVENEVSRRYVD
CCHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHC
DAPTFAELTWRRRAANKKQGSAEDFDPVSQAMLNDEYEAATADALRRYRLFLDHGVCPEQ
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHH
ARFLLPQAMMTTYWATGSLYAFAQAYVKRSDSHAQKEIQLLAAEWDRIIRPLFPVSWAAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
VD
CC
>Mature Secondary Structure 
GSDLTVVNAARVSFDRESDWLHAAGPRELSGKDKRLIRFLARGCESGEWEAHINELSDT
CCCCEEEHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCC
HDPAECGEILKWAKRLPEHWTPFAHTAITLREHVPVPVARQRFKHKVGFVENEVSRRYVD
CCHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHC
DAPTFAELTWRRRAANKKQGSAEDFDPVSQAMLNDEYEAATADALRRYRLFLDHGVCPEQ
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHH
ARFLLPQAMMTTYWATGSLYAFAQAYVKRSDSHAQKEIQLLAAEWDRIIRPLFPVSWAAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
VD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA