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The map label for this gene is nudL [H]

Identifier: 158425131

GI number: 158425131

Start: 4022247

End: 4022924

Strand: Reverse

Name: nudL [H]

Synonym: AZC_3507

Alternate gene names: 158425131

Gene position: 4022924-4022247 (Counterclockwise)

Preceding gene: 158425132

Following gene: 158425130

Centisome position: 74.92

GC content: 68.58

Gene sequence:

>678_bases
GTGATGACCGCCCCCTTTCCCTCCGCCGGGGCGCCGGTCGGCACGTCGTCGCCCGAGCTCGATGATTTCCTCGACCGCGC
CGCCTTCGGCCTCTCGCAGGTGCCGCCTCCGCCCTATGTGCGGGACGACCATGCGACGCTGAACGGCGACCACGCCATCT
CCAGCCATGTGCCGGTGCCGGAGAAGCCGCCGCGCCCGGCCGCCGTTCTGGTGCCCGTGGTGGCACGGCCAGAGCCCACG
GTGCTCCTGACGCTGCGGGCCACCAACCTCTCCCATCATGCCGGACAGATCGCCTTTCCCGGTGGGCGGATGGACCCGGA
GGACAAGGACGAGGTTGACACCGCCTTGCGCGAGGCGCGGGAGGAGGTGGGCCTTGCGGGCGATCTGGTGCGCCCTCTCG
GCTTCCTCGACGGGTACCTCTCCAGCACCAATTTCTGGATCGTACCCGTGGTCGGGCTCATCCCGCCCAATTACGCCCTC
GCCCTCAATGAAGCCGAGGTGCAGGAGGCGTTCGAGGTGCCGCTGGCCTTCCTGATGGACCCCGCCAACCACCAGCGCCA
GTCGCGGGTGCGCGAGGGCATCCGGCGCTATTTCTTCGCCATGCCCTATGGCGAGCGGTTCATCTGGGGCGTAACGGCCG
GGCTGATCCGCAACCTCTACGAGAAGCTCTACGCATGA

Upstream 100 bases:

>100_bases
GCGGCGAGGTGCGGGAGGTTGAGGGCACGGCGATGTTCGGCGTCGCCTCGGGCCGGGCCTTCTATGCCATGATGCCCGCC
GCCCAACTGGAAGGCAGCCT

Downstream 100 bases:

>100_bases
TCCGCACCGTTCTCGTGGAGACCGCGCTCTTCCTCTCGCCCTTCATTGCCTATGGCCTGATCCTGCTGGCGCTGCGCGGC
TCCGTGGTGCCGGCGCACTG

Product: nudix hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MMTAPFPSAGAPVGTSSPELDDFLDRAAFGLSQVPPPPYVRDDHATLNGDHAISSHVPVPEKPPRPAAVLVPVVARPEPT
VLLTLRATNLSHHAGQIAFPGGRMDPEDKDEVDTALREAREEVGLAGDLVRPLGFLDGYLSSTNFWIVPVVGLIPPNYAL
ALNEAEVQEAFEVPLAFLMDPANHQRQSRVREGIRRYFFAMPYGERFIWGVTAGLIRNLYEKLYA

Sequences:

>Translated_225_residues
MMTAPFPSAGAPVGTSSPELDDFLDRAAFGLSQVPPPPYVRDDHATLNGDHAISSHVPVPEKPPRPAAVLVPVVARPEPT
VLLTLRATNLSHHAGQIAFPGGRMDPEDKDEVDTALREAREEVGLAGDLVRPLGFLDGYLSSTNFWIVPVVGLIPPNYAL
ALNEAEVQEAFEVPLAFLMDPANHQRQSRVREGIRRYFFAMPYGERFIWGVTAGLIRNLYEKLYA
>Mature_225_residues
MMTAPFPSAGAPVGTSSPELDDFLDRAAFGLSQVPPPPYVRDDHATLNGDHAISSHVPVPEKPPRPAAVLVPVVARPEPT
VLLTLRATNLSHHAGQIAFPGGRMDPEDKDEVDTALREAREEVGLAGDLVRPLGFLDGYLSSTNFWIVPVVGLIPPNYAL
ALNEAEVQEAFEVPLAFLMDPANHQRQSRVREGIRRYFFAMPYGERFIWGVTAGLIRNLYEKLYA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=134, Percent_Identity=41.044776119403, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32469515, Length=95, Percent_Identity=44.2105263157895, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1788115, Length=203, Percent_Identity=37.9310344827586, Blast_Score=101, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17536993, Length=120, Percent_Identity=37.5, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17510677, Length=136, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859683, Length=146, Percent_Identity=39.041095890411, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 24662; Mature: 24662

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTAPFPSAGAPVGTSSPELDDFLDRAAFGLSQVPPPPYVRDDHATLNGDHAISSHVPVP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EKPPRPAAVLVPVVARPEPTVLLTLRATNLSHHAGQIAFPGGRMDPEDKDEVDTALREAR
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
EEVGLAGDLVRPLGFLDGYLSSTNFWIVPVVGLIPPNYALALNEAEVQEAFEVPLAFLMD
HHHCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCEEEEECHHHHHHHHHCCHHHHCC
PANHQRQSRVREGIRRYFFAMPYGERFIWGVTAGLIRNLYEKLYA
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTAPFPSAGAPVGTSSPELDDFLDRAAFGLSQVPPPPYVRDDHATLNGDHAISSHVPVP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EKPPRPAAVLVPVVARPEPTVLLTLRATNLSHHAGQIAFPGGRMDPEDKDEVDTALREAR
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
EEVGLAGDLVRPLGFLDGYLSSTNFWIVPVVGLIPPNYALALNEAEVQEAFEVPLAFLMD
HHHCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCEEEEECHHHHHHHHHCCHHHHCC
PANHQRQSRVREGIRRYFFAMPYGERFIWGVTAGLIRNLYEKLYA
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA