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The map label for this gene is glpE [H]

Identifier: 158425063

GI number: 158425063

Start: 3955704

End: 3956483

Strand: Reverse

Name: glpE [H]

Synonym: AZC_3439

Alternate gene names: 158425063

Gene position: 3956483-3955704 (Counterclockwise)

Preceding gene: 158425064

Following gene: 158425060

Centisome position: 73.68

GC content: 67.44

Gene sequence:

>780_bases
ATGACCTTCCGCGTTCCCTTCCGCCGCATCCATCCCGGCGAGGCGGAGGTGCTTCTCCGGCGGGACGATCTCCTCGTCTT
CGACACCCGCGATGCGTGCTCCTACGAGGCGGGTCACATGCCGGGCGCCCGGCGGCTTTCGCAGGCCAATCTCTCGGAGA
TCATCCTGGCGACACCGCGGCACCATCCCGTGCTGATCTATTGCTATCACGGCAATGCCAGCCAGGAATATGCGCAGACC
TTCGCCGATTTCGGCTTCCAGGACGTCTCCAGCCTCGATGACGGCTATGAGGGCTGGCGCACACGCGGCGCCACCCATGC
CATGCCCGACATCGATGCGGATCTCGCTGCCTGGCTCGTCGCCCACGGCTTTCCGGCCGATGACGTGGATGCGGTGATCG
ACAACGGCACCACGCCGCTCATGAAGGCGGCCCACACGGGCGACACGGAGGCGCTGTGCCAGCTCATCGCGGCGGGCGCG
CATCTCGATCTGCGCAATGCCGATGGCAACACGGCGCTGTGGCTCGCCTGCGTCGGCCGGCATCTGGACGCCATCGACAT
GCTGGTGGCTGCCGGCATCGACATCGACAACCAGAATGACAACGGCGCGACCGCCCTGATGTATGCGTCTTCGGCCGGCC
TCGGTCCGGTGGTGGGCCGTCTCCTCGCGCGGGGCGCAGATGCGGAGCTCGAAACGCTGGACGGCTTCACGGCGCTGGAT
CTTGCGGGCACGGTAGAATGCCTGGCGCTCCTGCGCCCCGCACGACAGGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
AGTTCACCGTCGGCCGGCCGCTCCATGACGGGCGCATCCTGTCGCTGCCCGCCTATCCCGGCCGCCGCCCGCCTCCCGCC
CCTGCACAGGAGCCGCTCGC

Downstream 100 bases:

>100_bases
GGCCCGCCGCGCACGTCGGTATCAGGCGGCCCTGGGGGCGATGCCCTTCTCACTGAACAGGGCCTGAAGCTCGCCCTTCT
GCGCCATCTCGCGGACGATG

Product: rhodanese-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTFRVPFRRIHPGEAEVLLRRDDLLVFDTRDACSYEAGHMPGARRLSQANLSEIILATPRHHPVLIYCYHGNASQEYAQT
FADFGFQDVSSLDDGYEGWRTRGATHAMPDIDADLAAWLVAHGFPADDVDAVIDNGTTPLMKAAHTGDTEALCQLIAAGA
HLDLRNADGNTALWLACVGRHLDAIDMLVAAGIDIDNQNDNGATALMYASSAGLGPVVGRLLARGADAELETLDGFTALD
LAGTVECLALLRPARQAAG

Sequences:

>Translated_259_residues
MTFRVPFRRIHPGEAEVLLRRDDLLVFDTRDACSYEAGHMPGARRLSQANLSEIILATPRHHPVLIYCYHGNASQEYAQT
FADFGFQDVSSLDDGYEGWRTRGATHAMPDIDADLAAWLVAHGFPADDVDAVIDNGTTPLMKAAHTGDTEALCQLIAAGA
HLDLRNADGNTALWLACVGRHLDAIDMLVAAGIDIDNQNDNGATALMYASSAGLGPVVGRLLARGADAELETLDGFTALD
LAGTVECLALLRPARQAAG
>Mature_258_residues
TFRVPFRRIHPGEAEVLLRRDDLLVFDTRDACSYEAGHMPGARRLSQANLSEIILATPRHHPVLIYCYHGNASQEYAQTF
ADFGFQDVSSLDDGYEGWRTRGATHAMPDIDADLAAWLVAHGFPADDVDAVIDNGTTPLMKAAHTGDTEALCQLIAAGAH
LDLRNADGNTALWLACVGRHLDAIDMLVAAGIDIDNQNDNGATALMYASSAGLGPVVGRLLARGADAELETLDGFTALDL
AGTVECLALLRPARQAAG

Specific function: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide [H]

COG id: COG0666

COG function: function code R; FOG: Ankyrin repeat

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI38683807, Length=206, Percent_Identity=33.0097087378641, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI38683816, Length=206, Percent_Identity=33.0097087378641, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI46519147, Length=206, Percent_Identity=33.495145631068, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37620163, Length=206, Percent_Identity=33.495145631068, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46519154, Length=206, Percent_Identity=33.495145631068, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46519151, Length=206, Percent_Identity=33.495145631068, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI70995267, Length=125, Percent_Identity=36.8, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161084156, Length=112, Percent_Identity=36.6071428571429, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281366282, Length=112, Percent_Identity=36.6071428571429, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281366284, Length=112, Percent_Identity=36.6071428571429, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161084152, Length=112, Percent_Identity=36.6071428571429, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281366286, Length=112, Percent_Identity=36.6071428571429, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28571867, Length=90, Percent_Identity=40, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28571865, Length=90, Percent_Identity=40, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.1 [H]

Molecular weight: Translated: 27694; Mature: 27563

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRVPFRRIHPGEAEVLLRRDDLLVFDTRDACSYEAGHMPGARRLSQANLSEIILATPR
CCCCCCHHHCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCHHHHHHCCHHHEEEECCC
HHPVLIYCYHGNASQEYAQTFADFGFQDVSSLDDGYEGWRTRGATHAMPDIDADLAAWLV
CCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHH
AHGFPADDVDAVIDNGTTPLMKAAHTGDTEALCQLIAAGAHLDLRNADGNTALWLACVGR
HCCCCCCCHHHHHCCCCCHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEHHHC
HLDAIDMLVAAGIDIDNQNDNGATALMYASSAGLGPVVGRLLARGADAELETLDGFTALD
CHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCHHHH
LAGTVECLALLRPARQAAG
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFRVPFRRIHPGEAEVLLRRDDLLVFDTRDACSYEAGHMPGARRLSQANLSEIILATPR
CCCCCHHHCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCHHHHHHCCHHHEEEECCC
HHPVLIYCYHGNASQEYAQTFADFGFQDVSSLDDGYEGWRTRGATHAMPDIDADLAAWLV
CCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHH
AHGFPADDVDAVIDNGTTPLMKAAHTGDTEALCQLIAAGAHLDLRNADGNTALWLACVGR
HCCCCCCCHHHHHCCCCCHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEHHHC
HLDAIDMLVAAGIDIDNQNDNGATALMYASSAGLGPVVGRLLARGADAELETLDGFTALD
CHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCHHHH
LAGTVECLALLRPARQAAG
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA