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The map label for this gene is cysJ [H]

Identifier: 158425049

GI number: 158425049

Start: 3947959

End: 3949386

Strand: Direct

Name: cysJ [H]

Synonym: AZC_3425

Alternate gene names: 158425049

Gene position: 3947959-3949386 (Clockwise)

Preceding gene: 158425048

Following gene: 158425051

Centisome position: 73.52

GC content: 69.61

Gene sequence:

>1428_bases
GTGATATCCGGAGATGATCATGGTGCCGCACACCCGACAGCCCGCAGACCTTTCGCCACCGGCCTGCGCGGGAGCGGCCC
CATGAACCATCCCATCACCCACTGGCCTCAGACGGGGGCGCCCGTCCCCCCGCCTGACCTTGCCCTGGATGGGCGGGACA
AGCCGACCCTCGGCGAGTCGTCGGCAAGCGCTGCCGCTCTGCCCGTTGCGGACGCGCCCGGCAGCTTCGCGCGTGCCCTG
CTTGATCTCGACACGCTGACGCCGGCAGCGCGCGCGGACGTACGCGCGCTCCTCGCCGCTCACGGCCTCTGTGCGCCCGA
GATGGGGCGGCCACCTGCCGCTCCGGCCCGTCCTTCGGCCGACGCTTCGGATACGGCGGATCTCCTCCCTTTCGATGCCC
TGCTGAAATGCCGGCGCCGCCTTGGCCGCGCCGGCTCATCGCAACCCGCCGTGCATGTGGAACTCGATCTCAGCGAGACG
CCGGTCGCGGTCCAGCCCGGAGATGCCATCGGCATCCTGCCGGAGAACGACCCGATCCTCGTGCAGCGCATCCTCGCCCA
TCTCGGCCTGTGCGGCCGGCGCCTCGCGGATGGCGAAAGCCTGCGCGCCCACCTTCTGGCGCGTTACGATCTCGACCATG
CGACGCCGGATCTGTTCCAGTTGATTGCGACCCTTGCAACGGGCGAACGACGGGACACCGCCCTCGCGCTGCGCGATGCC
CCTGCGCCCGCCATGGACGTGCTTTCGGCGCTCGGCCTGCTCTCGCGCTTCCGGCCGAGTCCGGAGGCGCTGCTCGCGTG
CCTCGCCCCCCTCGAACCCCGCTTCCATCTCGTGACCTCCAGCGCCCGTCTCCACCCGGGCATCGCGGCCCTCGTGGTGG
AGAAGGAGGACAAAGGGAGTGCGCTGACGTTCCTGAGCACGCGTGCGCCGGTGGGCTCCCGCCTTCAGTGCCTGCTGCGG
CGGGCGCCGCACTTCCGCCTGCCGCAGCAAAGGGATGTTCCGCTCATCATGATCGGCGCAGGCGTAGGGATCGCCCCCTT
CCGGGCCTTCCTGCAGGACCGGCGGGCGCGCATGGAGTCCGGGCCCGCCTGGCTGTTCTTCAGCCATGCCAGCGCCGCCA
CCGATTATTTCTACGAGGACGAATTGCGGGCCTTCCGCGCGCAGGGACACCTCACCACCCTCACCACGGCCTGGACGCAG
TCCGGCCCTCAAGCAGGAAGCTTGGAAGGGCGGCTTGCGGAAGCCGCTCCTGAGCTGCTCGCCTGGATCAGCGAGGGCGC
TCATGTCTATGTCTGTGGCGACGATGTGGTGACGGCCGGCGTCGAGCGGACCATGGTTGGTCTCCTCGCGAGTCACCTGG
CATTAGCCGGAGCGGGGGATCTCGACGCGCTCAAGGCGCAGGATCGCTATCACGTCGAGCACCTCTGA

Upstream 100 bases:

>100_bases
TGCCGAGCACCTACCAGGCCCTCGCCGGCGGCCGCGGCGTGTTCCGCATCCCGACGGAAGCGCTCCCGGCGCTGAAGGCA
AGCGCCGCCCCCGCCGCCGC

Downstream 100 bases:

>100_bases
TCAGAGGCGTCCGCCCGGCCCATTCTCGATGCGTCATGCGGGCTCCACCGCGTCGGCAATCGCGACTTGGCCGAGCTTCG
ACGGAGCGTAGCCCTCTTCC

Product: oxidoreductase

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MISGDDHGAAHPTARRPFATGLRGSGPMNHPITHWPQTGAPVPPPDLALDGRDKPTLGESSASAAALPVADAPGSFARAL
LDLDTLTPAARADVRALLAAHGLCAPEMGRPPAAPARPSADASDTADLLPFDALLKCRRRLGRAGSSQPAVHVELDLSET
PVAVQPGDAIGILPENDPILVQRILAHLGLCGRRLADGESLRAHLLARYDLDHATPDLFQLIATLATGERRDTALALRDA
PAPAMDVLSALGLLSRFRPSPEALLACLAPLEPRFHLVTSSARLHPGIAALVVEKEDKGSALTFLSTRAPVGSRLQCLLR
RAPHFRLPQQRDVPLIMIGAGVGIAPFRAFLQDRRARMESGPAWLFFSHASAATDYFYEDELRAFRAQGHLTTLTTAWTQ
SGPQAGSLEGRLAEAAPELLAWISEGAHVYVCGDDVVTAGVERTMVGLLASHLALAGAGDLDALKAQDRYHVEHL

Sequences:

>Translated_475_residues
MISGDDHGAAHPTARRPFATGLRGSGPMNHPITHWPQTGAPVPPPDLALDGRDKPTLGESSASAAALPVADAPGSFARAL
LDLDTLTPAARADVRALLAAHGLCAPEMGRPPAAPARPSADASDTADLLPFDALLKCRRRLGRAGSSQPAVHVELDLSET
PVAVQPGDAIGILPENDPILVQRILAHLGLCGRRLADGESLRAHLLARYDLDHATPDLFQLIATLATGERRDTALALRDA
PAPAMDVLSALGLLSRFRPSPEALLACLAPLEPRFHLVTSSARLHPGIAALVVEKEDKGSALTFLSTRAPVGSRLQCLLR
RAPHFRLPQQRDVPLIMIGAGVGIAPFRAFLQDRRARMESGPAWLFFSHASAATDYFYEDELRAFRAQGHLTTLTTAWTQ
SGPQAGSLEGRLAEAAPELLAWISEGAHVYVCGDDVVTAGVERTMVGLLASHLALAGAGDLDALKAQDRYHVEHL
>Mature_475_residues
MISGDDHGAAHPTARRPFATGLRGSGPMNHPITHWPQTGAPVPPPDLALDGRDKPTLGESSASAAALPVADAPGSFARAL
LDLDTLTPAARADVRALLAAHGLCAPEMGRPPAAPARPSADASDTADLLPFDALLKCRRRLGRAGSSQPAVHVELDLSET
PVAVQPGDAIGILPENDPILVQRILAHLGLCGRRLADGESLRAHLLARYDLDHATPDLFQLIATLATGERRDTALALRDA
PAPAMDVLSALGLLSRFRPSPEALLACLAPLEPRFHLVTSSARLHPGIAALVVEKEDKGSALTFLSTRAPVGSRLQCLLR
RAPHFRLPQQRDVPLIMIGAGVGIAPFRAFLQDRRARMESGPAWLFFSHASAATDYFYEDELRAFRAQGHLTTLTTAWTQ
SGPQAGSLEGRLAEAAPELLAWISEGAHVYVCGDDVVTAGVERTMVGLLASHLALAGAGDLDALKAQDRYHVEHL

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=408, Percent_Identity=28.4313725490196, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI40254422, Length=400, Percent_Identity=29.25, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI24041029, Length=400, Percent_Identity=28.25, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI169790958, Length=402, Percent_Identity=25.8706467661692, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI169790956, Length=402, Percent_Identity=25.8706467661692, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI10835173, Length=399, Percent_Identity=25.8145363408521, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI7657393, Length=393, Percent_Identity=25.1908396946565, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI221316709, Length=386, Percent_Identity=24.8704663212435, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI221316705, Length=402, Percent_Identity=24.8756218905473, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI221316707, Length=327, Percent_Identity=25.9938837920489, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789123, Length=367, Percent_Identity=30.7901907356948, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17554134, Length=378, Percent_Identity=26.4550264550265, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321143, Length=385, Percent_Identity=25.4545454545455, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321832, Length=150, Percent_Identity=30.6666666666667, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137192, Length=411, Percent_Identity=26.2773722627737, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24582192, Length=412, Percent_Identity=26.6990291262136, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24583543, Length=375, Percent_Identity=27.4666666666667, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78706876, Length=375, Percent_Identity=27.4666666666667, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78706872, Length=368, Percent_Identity=27.7173913043478, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 50359; Mature: 50359

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGDDHGAAHPTARRPFATGLRGSGPMNHPITHWPQTGAPVPPPDLALDGRDKPTLGES
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
SASAAALPVADAPGSFARALLDLDTLTPAARADVRALLAAHGLCAPEMGRPPAAPARPSA
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DASDTADLLPFDALLKCRRRLGRAGSSQPAVHVELDLSETPVAVQPGDAIGILPENDPIL
CCCCCHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEECCCCEEEECCCCCHHH
VQRILAHLGLCGRRLADGESLRAHLLARYDLDHATPDLFQLIATLATGERRDTALALRDA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
PAPAMDVLSALGLLSRFRPSPEALLACLAPLEPRFHLVTSSARLHPGIAALVVEKEDKGS
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEECCCCC
ALTFLSTRAPVGSRLQCLLRRAPHFRLPQQRDVPLIMIGAGVGIAPFRAFLQDRRARMES
EEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
GPAWLFFSHASAATDYFYEDELRAFRAQGHLTTLTTAWTQSGPQAGSLEGRLAEAAPELL
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHH
AWISEGAHVYVCGDDVVTAGVERTMVGLLASHLALAGAGDLDALKAQDRYHVEHL
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MISGDDHGAAHPTARRPFATGLRGSGPMNHPITHWPQTGAPVPPPDLALDGRDKPTLGES
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
SASAAALPVADAPGSFARALLDLDTLTPAARADVRALLAAHGLCAPEMGRPPAAPARPSA
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DASDTADLLPFDALLKCRRRLGRAGSSQPAVHVELDLSETPVAVQPGDAIGILPENDPIL
CCCCCHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEECCCCEEEECCCCCHHH
VQRILAHLGLCGRRLADGESLRAHLLARYDLDHATPDLFQLIATLATGERRDTALALRDA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
PAPAMDVLSALGLLSRFRPSPEALLACLAPLEPRFHLVTSSARLHPGIAALVVEKEDKGS
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEECCCCC
ALTFLSTRAPVGSRLQCLLRRAPHFRLPQQRDVPLIMIGAGVGIAPFRAFLQDRRARMES
EEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
GPAWLFFSHASAATDYFYEDELRAFRAQGHLTTLTTAWTQSGPQAGSLEGRLAEAAPELL
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHH
AWISEGAHVYVCGDDVVTAGVERTMVGLLASHLALAGAGDLDALKAQDRYHVEHL
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA