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The map label for this gene is sseA [H]

Identifier: 158425027

GI number: 158425027

Start: 3931343

End: 3932203

Strand: Reverse

Name: sseA [H]

Synonym: AZC_3403

Alternate gene names: 158425027

Gene position: 3932203-3931343 (Counterclockwise)

Preceding gene: 158425028

Following gene: 158425026

Centisome position: 73.23

GC content: 68.41

Gene sequence:

>861_bases
ATGTCGTCATCCGCCTTTGAAACGCCTGTCGTCAGCACCGAATGGCTCGCCGCGCATCTGGGCGAGGGGGATCTGCGCAT
CCTCGACTGCACCTGGCATCATCCGAGCACCAATCTGGATGGCCGCACGCAGTATCGGGGCCGTCACCTGCCGGGCGCGG
TGCATTTCGACATCGATCAGGTGGCCGACAAGACCAACCCGCTGCCGCACATGCTGCCCAAGGAGGAGGATTTCGCCGCC
AAGATGGGGCTGCTCGGTGTGGGCACAGGCGATCGCGCGGTGGTCTATGACCGGCTGTGCGGCGGGGCCGCTGCCGCCCG
CGCCTGGTGGATGTTCCGGGTCTTCGGCCATGAGAACGTGGCGCTGCTGGACGGCGGCTATGCCAAATGGGCGGCCGAGA
AGCGGCCCGCCGAGATGGCGCCCGTGCGGCCAGAGGCGCGCAGCTTCACCGCCGGCTTCAATCCGGCGCTCCTGCGCACG
CTGGACCAGATGAAGGCGAATCTCGCCTCCGGCGCCGAACAGGTTCTGGACGCGCGTGGGCCCGGCAAGTTCGATGGCAC
GCAGGAGGATGTCTATGCCTTCGCCAAGCGTGGCCACATGCCCAACGCGGTGAATGTGCCGTGGGGCGATCTCGTCGATA
CCCAGACGGGAGCCCTCGTCGCCCCGGAGGCGATCTCTGCCCGCTTCGCGGCGGCCGGTGTCGATCTCGACAGGCCCATC
GTCACCACCTGCGCCTCCGGCATTCTCGCGCCCATGCTGTCGTTGGCGCTGAAGCTGCTGGGGCGGGAGGCCCCGGTCTA
TGACGGCTCCTGGGCCGAGTGGGAAAAGGCTGCCGACGCGCCGGTGGCGGCTGCCGCCTGA

Upstream 100 bases:

>100_bases
CTGCACAAGGCGCTCTGAAACCGGCAGGTGCGTCGTGGGTTTCGGCCCCGCCGCACCTGCCTTCCACCGTGATATCGCGT
GAGCTGCGGGAGATCTGTCG

Downstream 100 bases:

>100_bases
GGGAGGGCGCCATGTCGGATGCGGCGGAAACCCTGCTCTCCGGCGCGGAGTATGAACTCCTCGCCGGGCCGGGCGCGGGC
GCCTACCGGCTGCGGTGCAA

Product: rhodanese-related sulfurtransferase

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSSSAFETPVVSTEWLAAHLGEGDLRILDCTWHHPSTNLDGRTQYRGRHLPGAVHFDIDQVADKTNPLPHMLPKEEDFAA
KMGLLGVGTGDRAVVYDRLCGGAAAARAWWMFRVFGHENVALLDGGYAKWAAEKRPAEMAPVRPEARSFTAGFNPALLRT
LDQMKANLASGAEQVLDARGPGKFDGTQEDVYAFAKRGHMPNAVNVPWGDLVDTQTGALVAPEAISARFAAAGVDLDRPI
VTTCASGILAPMLSLALKLLGREAPVYDGSWAEWEKAADAPVAAAA

Sequences:

>Translated_286_residues
MSSSAFETPVVSTEWLAAHLGEGDLRILDCTWHHPSTNLDGRTQYRGRHLPGAVHFDIDQVADKTNPLPHMLPKEEDFAA
KMGLLGVGTGDRAVVYDRLCGGAAAARAWWMFRVFGHENVALLDGGYAKWAAEKRPAEMAPVRPEARSFTAGFNPALLRT
LDQMKANLASGAEQVLDARGPGKFDGTQEDVYAFAKRGHMPNAVNVPWGDLVDTQTGALVAPEAISARFAAAGVDLDRPI
VTTCASGILAPMLSLALKLLGREAPVYDGSWAEWEKAADAPVAAAA
>Mature_285_residues
SSSAFETPVVSTEWLAAHLGEGDLRILDCTWHHPSTNLDGRTQYRGRHLPGAVHFDIDQVADKTNPLPHMLPKEEDFAAK
MGLLGVGTGDRAVVYDRLCGGAAAARAWWMFRVFGHENVALLDGGYAKWAAEKRPAEMAPVRPEARSFTAGFNPALLRTL
DQMKANLASGAEQVLDARGPGKFDGTQEDVYAFAKRGHMPNAVNVPWGDLVDTQTGALVAPEAISARFAAAGVDLDRPIV
TTCASGILAPMLSLALKLLGREAPVYDGSWAEWEKAADAPVAAAA

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI194473668, Length=280, Percent_Identity=40.3571428571429, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI61835204, Length=280, Percent_Identity=40.3571428571429, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI194473681, Length=280, Percent_Identity=40.3571428571429, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI17402865, Length=276, Percent_Identity=40.9420289855072, Blast_Score=206, Evalue=2e-53,
Organism=Escherichia coli, GI87082121, Length=285, Percent_Identity=38.2456140350877, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI87081967, Length=275, Percent_Identity=24, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561888, Length=300, Percent_Identity=26.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71997283, Length=292, Percent_Identity=25.3424657534247, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115534702, Length=198, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559150, Length=284, Percent_Identity=26.7605633802817, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17543836, Length=291, Percent_Identity=26.8041237113402, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17543838, Length=291, Percent_Identity=26.8041237113402, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324825, Length=266, Percent_Identity=31.5789473684211, Blast_Score=129, Evalue=8e-31,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 30615; Mature: 30484

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00380 RHODANESE_1 ; PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSAFETPVVSTEWLAAHLGEGDLRILDCTWHHPSTNLDGRTQYRGRHLPGAVHFDIDQ
CCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHH
VADKTNPLPHMLPKEEDFAAKMGLLGVGTGDRAVVYDRLCGGAAAARAWWMFRVFGHENV
HHHCCCCCCCCCCCCHHHHHHHCEEEECCCCCEEHHHHHHCCHHHHHHHHHEEEECCCCE
ALLDGGYAKWAAEKRPAEMAPVRPEARSFTAGFNPALLRTLDQMKANLASGAEQVLDARG
EEEECCHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PGKFDGTQEDVYAFAKRGHMPNAVNVPWGDLVDTQTGALVAPEAISARFAAAGVDLDRPI
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCCCHH
VTTCASGILAPMLSLALKLLGREAPVYDGSWAEWEKAADAPVAAAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSSAFETPVVSTEWLAAHLGEGDLRILDCTWHHPSTNLDGRTQYRGRHLPGAVHFDIDQ
CCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHH
VADKTNPLPHMLPKEEDFAAKMGLLGVGTGDRAVVYDRLCGGAAAARAWWMFRVFGHENV
HHHCCCCCCCCCCCCHHHHHHHCEEEECCCCCEEHHHHHHCCHHHHHHHHHEEEECCCCE
ALLDGGYAKWAAEKRPAEMAPVRPEARSFTAGFNPALLRTLDQMKANLASGAEQVLDARG
EEEECCHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PGKFDGTQEDVYAFAKRGHMPNAVNVPWGDLVDTQTGALVAPEAISARFAAAGVDLDRPI
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCCCHH
VTTCASGILAPMLSLALKLLGREAPVYDGSWAEWEKAADAPVAAAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]