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The map label for this gene is pncB [H]

Identifier: 158425001

GI number: 158425001

Start: 3905748

End: 3907040

Strand: Reverse

Name: pncB [H]

Synonym: AZC_3377

Alternate gene names: 158425001

Gene position: 3907040-3905748 (Counterclockwise)

Preceding gene: 158425003

Following gene: 158424999

Centisome position: 72.76

GC content: 66.05

Gene sequence:

>1293_bases
ATGACCGACATCGCCACCCGCGTCTATAATCATACGTGGAAGATCGACCCCATCGTCCGTTCGGTCCTCGACACGGATTT
CTACAAGCTGCTCATGGGGCAGATGATCTTCCGGCGGCACCGGGACGTGCAGGTGGCCTTCGGCATCCACAACCGCACCA
GCCGCGTGCGCCTGGCCGAGATCATCGACGACGGTGCGCTGCGCGAGCAACTGGATCATGTGCGCTCGCTCTCCCTGTCG
CGGGGCGAATCCACCTGGCTGCGCGGCAACATGTTCTACGGCAAGCGGCAGATGTTTGCGCCGGACTATCTGGCCTGGCT
GGAGAACTTCCGATTCCCCGCCTATCATCTGGAAAAGCGCGACGGGCAGTATGAGCTGATCTTCGAGGGACCGTGGATCG
AGACCACCATGTGGGAGGTTCCGGCCCTCGCCGTCATCAACGAATTGCGCTCGCGGGCGGTGCTGAAGGGGCTCGGACGC
TTCGAGCTTCAGGTGCTCTATGCCCGCGCCATGACGCGGGTGTGGGAGAAGATCGAGTTCCTGAAAAGCCTCGGCCCGGT
CAATCTCGCGGACTTCGGCACCCGGCGCCGCCACGGCTTCCTGTGGCAGGACTGGTGCGTGCAGGCGCTGAGCGAGGGGC
TTGGCCCCACCTTCCTCGGCACCTCGAACTGCCTCATCGCCATGCGCCGCGAGGTGGAGGCAACCGGCACCAACGCCCAC
GAGCTTCCCATGGTCTATGCCGCGCTCGCGCAGGACGATGCGGCGCTGGCCGCCGCGCCCTATGAGGTGCTTGCCGACTG
GCAGCAGGAATATGATGGCAACCTGCGCATCATCCTGCCGGACACCTATGGCAGCACGGGCTTCCTCGCCCATGCGCCGG
ACTGGGTGGCGGGCTGGACCGGCATCCGCATCGACAGCAAGGACCCGCTGGAAGGGGGCGAGGAAGCGATCGCCTGGTGG
ACGGCGCGCGGGCAGAATCCGCAGGAAAAGCTGGCCATCTTCTCGGACGGGCTCGATGCGGACGAGGTGGCCCGCATCCA
TGCCCGGTTCAAGGGGCGGATGCGGCTCGGTTTCGGCTGGGGGACGCTGCTGACGAACGACTTCCGGGGCCTGGCGTCCG
ATGGGGTCCTCGACCCCATTTCCATCGTATGCAAGGTGATCTCGGCCAATGGCCGCCCGGCGGTGAAGCTCTCCGACAAT
CCCACCAAGGCCATGGGGCCGCCGGACCAGATCGCCCGCTACCGGCGGGTGTTCGAGGTGGGCGCGCAGGCCGAGCGGCG
GGTGGTGGTGTAA

Upstream 100 bases:

>100_bases
CAAGGACAACGGAACGGGGAACGGGCGGGTTCCGGCGCGGGGAACTCCCCATGGGGCCGCGAATGGTATAGGAGGCTGAA
GGCGCATCCCGAGGGCCGCC

Downstream 100 bases:

>100_bases
GCCGACCCGCTGCCGTCGCGCCGCTCAGGCGCCGCCCTGGAAGGTCTCGGCCGAGGGGATGGTCGCCGTGGCGATGAGCG
AGCGGTAGCGGCGCCGGGCG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQMIFRRHRDVQVAFGIHNRTSRVRLAEIIDDGALREQLDHVRSLSLS
RGESTWLRGNMFYGKRQMFAPDYLAWLENFRFPAYHLEKRDGQYELIFEGPWIETTMWEVPALAVINELRSRAVLKGLGR
FELQVLYARAMTRVWEKIEFLKSLGPVNLADFGTRRRHGFLWQDWCVQALSEGLGPTFLGTSNCLIAMRREVEATGTNAH
ELPMVYAALAQDDAALAAAPYEVLADWQQEYDGNLRIILPDTYGSTGFLAHAPDWVAGWTGIRIDSKDPLEGGEEAIAWW
TARGQNPQEKLAIFSDGLDADEVARIHARFKGRMRLGFGWGTLLTNDFRGLASDGVLDPISIVCKVISANGRPAVKLSDN
PTKAMGPPDQIARYRRVFEVGAQAERRVVV

Sequences:

>Translated_430_residues
MTDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQMIFRRHRDVQVAFGIHNRTSRVRLAEIIDDGALREQLDHVRSLSLS
RGESTWLRGNMFYGKRQMFAPDYLAWLENFRFPAYHLEKRDGQYELIFEGPWIETTMWEVPALAVINELRSRAVLKGLGR
FELQVLYARAMTRVWEKIEFLKSLGPVNLADFGTRRRHGFLWQDWCVQALSEGLGPTFLGTSNCLIAMRREVEATGTNAH
ELPMVYAALAQDDAALAAAPYEVLADWQQEYDGNLRIILPDTYGSTGFLAHAPDWVAGWTGIRIDSKDPLEGGEEAIAWW
TARGQNPQEKLAIFSDGLDADEVARIHARFKGRMRLGFGWGTLLTNDFRGLASDGVLDPISIVCKVISANGRPAVKLSDN
PTKAMGPPDQIARYRRVFEVGAQAERRVVV
>Mature_429_residues
TDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQMIFRRHRDVQVAFGIHNRTSRVRLAEIIDDGALREQLDHVRSLSLSR
GESTWLRGNMFYGKRQMFAPDYLAWLENFRFPAYHLEKRDGQYELIFEGPWIETTMWEVPALAVINELRSRAVLKGLGRF
ELQVLYARAMTRVWEKIEFLKSLGPVNLADFGTRRRHGFLWQDWCVQALSEGLGPTFLGTSNCLIAMRREVEATGTNAHE
LPMVYAALAQDDAALAAAPYEVLADWQQEYDGNLRIILPDTYGSTGFLAHAPDWVAGWTGIRIDSKDPLEGGEEAIAWWT
ARGQNPQEKLAIFSDGLDADEVARIHARFKGRMRLGFGWGTLLTNDFRGLASDGVLDPISIVCKVISANGRPAVKLSDNP
TKAMGPPDQIARYRRVFEVGAQAERRVVV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=414, Percent_Identity=34.7826086956522, Blast_Score=199, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324783, Length=421, Percent_Identity=28.978622327791, Blast_Score=159, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 48758; Mature: 48627

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQMIFRRHRDVQVAFGIHNRTSRVRLAE
CCCHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
IIDDGALREQLDHVRSLSLSRGESTWLRGNMFYGKRQMFAPDYLAWLENFRFPAYHLEKR
HHCCHHHHHHHHHHHHHHCCCCCCCEEECCEEECCCCCCCHHHHHHHHHCCCCCEEHHCC
DGQYELIFEGPWIETTMWEVPALAVINELRSRAVLKGLGRFELQVLYARAMTRVWEKIEF
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LKSLGPVNLADFGTRRRHGFLWQDWCVQALSEGLGPTFLGTSNCLIAMRREVEATGTNAH
HHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCH
ELPMVYAALAQDDAALAAAPYEVLADWQQEYDGNLRIILPDTYGSTGFLAHAPDWVAGWT
HHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCHHCCCE
GIRIDSKDPLEGGEEAIAWWTARGQNPQEKLAIFSDGLDADEVARIHARFKGRMRLGFGW
EEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECH
GTLLTNDFRGLASDGVLDPISIVCKVISANGRPAVKLSDNPTKAMGPPDQIARYRRVFEV
HHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
GAQAERRVVV
CCCCCCCCCC
>Mature Secondary Structure 
TDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQMIFRRHRDVQVAFGIHNRTSRVRLAE
CCHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
IIDDGALREQLDHVRSLSLSRGESTWLRGNMFYGKRQMFAPDYLAWLENFRFPAYHLEKR
HHCCHHHHHHHHHHHHHHCCCCCCCEEECCEEECCCCCCCHHHHHHHHHCCCCCEEHHCC
DGQYELIFEGPWIETTMWEVPALAVINELRSRAVLKGLGRFELQVLYARAMTRVWEKIEF
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LKSLGPVNLADFGTRRRHGFLWQDWCVQALSEGLGPTFLGTSNCLIAMRREVEATGTNAH
HHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCH
ELPMVYAALAQDDAALAAAPYEVLADWQQEYDGNLRIILPDTYGSTGFLAHAPDWVAGWT
HHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCHHCCCE
GIRIDSKDPLEGGEEAIAWWTARGQNPQEKLAIFSDGLDADEVARIHARFKGRMRLGFGW
EEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECH
GTLLTNDFRGLASDGVLDPISIVCKVISANGRPAVKLSDNPTKAMGPPDQIARYRRVFEV
HHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
GAQAERRVVV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA