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The map label for this gene is mrp [H]

Identifier: 158424987

GI number: 158424987

Start: 3891638

End: 3892861

Strand: Reverse

Name: mrp [H]

Synonym: AZC_3363

Alternate gene names: 158424987

Gene position: 3892861-3891638 (Counterclockwise)

Preceding gene: 158424988

Following gene: 158424986

Centisome position: 72.5

GC content: 69.61

Gene sequence:

>1224_bases
GTGAGGGTGGGGTTTCTTCCGCGCGCGAGCGTGGCATACAGGGTTTCAAATGTGGCGCGAGGCGCCGAAGCGTTTGGGAG
AGGACCAATGGCCGACATCACCGAAGATATGGTGCGCAGCGCGCTCGGCTCCGTGCGGACGCCGGAAGGGGTGGCGCTGG
CCGTTTCTCCGGCGCTGTCGGGCATCGTGGTCACCAGCGGCAAGGTCTATCTGTCCGTCACCGTGGATGCGGCGCAGGCC
CGCGCCTGGGAAAGCGTGCGCGCCGAGGCGGAAGACGCGGTGCGCACCATTCCGGGTGTCGCCTCGGCACTGGTGGCGCT
CACCGCCGAACGCAAGGCGGGCGCCCGCCCGGCCGCCCCCCCGCCGCCGGCCGTTGGCGGCCATGGCCACAGCCACGGAC
CGGCGAAGGGCGGTGCCATCGAGGTGCCCGGCGTTGCCTCCATCATCGCGGTCGCCTCGGGCAAGGGGGGCGTCGGCAAG
TCCACCGTGTCCATCAATCTGGCGCTGGCGCTGCGCGATCTCGGCCTCAAGGTCGGCCTGCTGGATGCGGACATTTACGG
CCCCTCCGTGCCGCGCCTCGCCGGCGTGCACGGCAAGCCGGAGGTGGAGGATGGGCGCATGATGCTGCCCATGGACAATT
TCGGCCTCCAGCTCATGTCCATCGGCTTCATGGTGGAGGAAGACACCCCCATGATCTGGCGCGGGCCGATGGTCATGTCG
GCCATCTCGCAGATGCTGCGCGAGGTGAAGTGGGGCCCGCTCGACGTGCTGGTGGTGGATATGCCGCCCGGCACGGGCGA
TGCCCAGCTGACCATGGCCCAGCAGGTCGGCCTTGCCGGTGCGGTCATCGTCTCGACCCCGCAGGATCTGGCGCTCATCG
ACGCCCGGCGCGGCATCGCCATGTTCAAGCGCGTGAATGTGCCGATCCTCGGCATCGTCGAGAACATGGCCACCTTCATC
TGTCCGCACTGCGGCGGCAGGTCCGACATCTTCGGCCATGGCGGCGCGCGGGCGGAAGCCGAGAAGCTCGGCGTGCCCTT
CCTCGGCGAGATCCCGCTGCACATGCGCATCCGCGAGATGTCTGACGCCGGCGTGCCGATCCTCGTGTCCGATCCCGACA
GTCCGCAGGCGGAAGGTTATCGCGCCATCGCGCAGCAGGTGCGCTCGGCCATCAGCCGCAGCGGCGCCTCCGCCCGCCCG
GCCCCGCGCATCGTCATCGAGTGA

Upstream 100 bases:

>100_bases
CCTGGCGCAACACGGGGTGGCTGAAGCGCAATCCCTGGTTCGAGCAGGATCTGCTTCCCGAGCTGCGCGCGGATATCGCA
CAGGCGCTCGCCCGGTCCGG

Downstream 100 bases:

>100_bases
GGCGCGGGCGGGGCTTTCAAAAGACCCATTTCGCAGACCGGGAAAAGCCATTAGAAGAAAGTCGAGGATGACCTCGGGTC
AGGGAGCCTTTAGTTCTCTG

Product: multidrug-resistance related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRVGFLPRASVAYRVSNVARGAEAFGRGPMADITEDMVRSALGSVRTPEGVALAVSPALSGIVVTSGKVYLSVTVDAAQA
RAWESVRAEAEDAVRTIPGVASALVALTAERKAGARPAAPPPPAVGGHGHSHGPAKGGAIEVPGVASIIAVASGKGGVGK
STVSINLALALRDLGLKVGLLDADIYGPSVPRLAGVHGKPEVEDGRMMLPMDNFGLQLMSIGFMVEEDTPMIWRGPMVMS
AISQMLREVKWGPLDVLVVDMPPGTGDAQLTMAQQVGLAGAVIVSTPQDLALIDARRGIAMFKRVNVPILGIVENMATFI
CPHCGGRSDIFGHGGARAEAEKLGVPFLGEIPLHMRIREMSDAGVPILVSDPDSPQAEGYRAIAQQVRSAISRSGASARP
APRIVIE

Sequences:

>Translated_407_residues
MRVGFLPRASVAYRVSNVARGAEAFGRGPMADITEDMVRSALGSVRTPEGVALAVSPALSGIVVTSGKVYLSVTVDAAQA
RAWESVRAEAEDAVRTIPGVASALVALTAERKAGARPAAPPPPAVGGHGHSHGPAKGGAIEVPGVASIIAVASGKGGVGK
STVSINLALALRDLGLKVGLLDADIYGPSVPRLAGVHGKPEVEDGRMMLPMDNFGLQLMSIGFMVEEDTPMIWRGPMVMS
AISQMLREVKWGPLDVLVVDMPPGTGDAQLTMAQQVGLAGAVIVSTPQDLALIDARRGIAMFKRVNVPILGIVENMATFI
CPHCGGRSDIFGHGGARAEAEKLGVPFLGEIPLHMRIREMSDAGVPILVSDPDSPQAEGYRAIAQQVRSAISRSGASARP
APRIVIE
>Mature_407_residues
MRVGFLPRASVAYRVSNVARGAEAFGRGPMADITEDMVRSALGSVRTPEGVALAVSPALSGIVVTSGKVYLSVTVDAAQA
RAWESVRAEAEDAVRTIPGVASALVALTAERKAGARPAAPPPPAVGGHGHSHGPAKGGAIEVPGVASIIAVASGKGGVGK
STVSINLALALRDLGLKVGLLDADIYGPSVPRLAGVHGKPEVEDGRMMLPMDNFGLQLMSIGFMVEEDTPMIWRGPMVMS
AISQMLREVKWGPLDVLVVDMPPGTGDAQLTMAQQVGLAGAVIVSTPQDLALIDARRGIAMFKRVNVPILGIVENMATFI
CPHCGGRSDIFGHGGARAEAEKLGVPFLGEIPLHMRIREMSDAGVPILVSDPDSPQAEGYRAIAQQVRSAISRSGASARP
APRIVIE

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=248, Percent_Identity=56.0483870967742, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI118572611, Length=254, Percent_Identity=43.3070866141732, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI6912540, Length=254, Percent_Identity=41.3385826771654, Blast_Score=192, Evalue=4e-49,
Organism=Escherichia coli, GI87082045, Length=255, Percent_Identity=52.9411764705882, Blast_Score=267, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI25143050, Length=258, Percent_Identity=38.7596899224806, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6321347, Length=258, Percent_Identity=41.0852713178295, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322188, Length=231, Percent_Identity=39.3939393939394, Blast_Score=186, Evalue=5e-48,
Organism=Drosophila melanogaster, GI221511043, Length=256, Percent_Identity=41.40625, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24667611, Length=254, Percent_Identity=43.7007874015748, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI19921440, Length=246, Percent_Identity=41.869918699187, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 42206; Mature: 42206

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGFLPRASVAYRVSNVARGAEAFGRGPMADITEDMVRSALGSVRTPEGVALAVSPALS
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
GIVVTSGKVYLSVTVDAAQARAWESVRAEAEDAVRTIPGVASALVALTAERKAGARPAAP
EEEEECCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
PPPAVGGHGHSHGPAKGGAIEVPGVASIIAVASGKGGVGKSTVSINLALALRDLGLKVGL
CCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEE
LDADIYGPSVPRLAGVHGKPEVEDGRMMLPMDNFGLQLMSIGFMVEEDTPMIWRGPMVMS
EECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEEECCCCEEEECHHHHH
AISQMLREVKWGPLDVLVVDMPPGTGDAQLTMAQQVGLAGAVIVSTPQDLALIDARRGIA
HHHHHHHHCCCCCEEEEEEECCCCCCCCEEEHHHHCCCCEEEEEECCCCCEEEHHHCCHH
MFKRVNVPILGIVENMATFICPHCGGRSDIFGHGGARAEAEKLGVPFLGEIPLHMRIREM
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCEECCCCCEEEEEEC
SDAGVPILVSDPDSPQAEGYRAIAQQVRSAISRSGASARPAPRIVIE
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
>Mature Secondary Structure
MRVGFLPRASVAYRVSNVARGAEAFGRGPMADITEDMVRSALGSVRTPEGVALAVSPALS
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
GIVVTSGKVYLSVTVDAAQARAWESVRAEAEDAVRTIPGVASALVALTAERKAGARPAAP
EEEEECCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
PPPAVGGHGHSHGPAKGGAIEVPGVASIIAVASGKGGVGKSTVSINLALALRDLGLKVGL
CCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEE
LDADIYGPSVPRLAGVHGKPEVEDGRMMLPMDNFGLQLMSIGFMVEEDTPMIWRGPMVMS
EECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEEECCCCEEEECHHHHH
AISQMLREVKWGPLDVLVVDMPPGTGDAQLTMAQQVGLAGAVIVSTPQDLALIDARRGIA
HHHHHHHHCCCCCEEEEEEECCCCCCCCEEEHHHHCCCCEEEEEECCCCCEEEHHHCCHH
MFKRVNVPILGIVENMATFICPHCGGRSDIFGHGGARAEAEKLGVPFLGEIPLHMRIREM
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCEECCCCCEEEEEEC
SDAGVPILVSDPDSPQAEGYRAIAQQVRSAISRSGASARPAPRIVIE
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]