| Definition | Azorhizobium caulinodans ORS 571, complete genome. |
|---|---|
| Accession | NC_009937 |
| Length | 5,369,772 |
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The map label for this gene is kduD [H]
Identifier: 158424958
GI number: 158424958
Start: 3861081
End: 3861836
Strand: Reverse
Name: kduD [H]
Synonym: AZC_3334
Alternate gene names: 158424958
Gene position: 3861836-3861081 (Counterclockwise)
Preceding gene: 158424959
Following gene: 158424957
Centisome position: 71.92
GC content: 67.86
Gene sequence:
>756_bases ATGACCTCTCCTTTTGACCTTTCCGGCAAACGCGCCATCGTCACCGGCGCCAATACGGGCCTTGGGCAGGCGATCGCGGT GGCCCTTGCTCAGGCTGGTGCCGGCATCGTCGCCGTGGGCCGCTCCGCCATGGACGAGACGGGTGAAGCCGTGCGCGCGG CGGGCGTCGCCTTCACCGAGGTGCGGGCGGATCTCGCGACGCTGGAGCCCATCGGCCGCATTGTCGAGGAGGCCTCCGTC GGCGGGCGCGTCGACATCCTCGTCAACAATGCGGGCATCATCCGCCGCGCCGACGCCATCGACTTCACCGAGGCCGATTG GGACGCGGTGATGGATGTGAACCTCAAGAGCACGTTCTTCCTCACCCAGGGGGTGGCGCGGGGCATGCTGGCGGACGGCA AGGGCGGCAAGGTGATCAACATCGCTTCGCTCCTCTCCTTCCAGGGTGGCATCCGCATCCCGTCCTACACGGCGAGCAAG AGCGGGCTGGCTGGCCTCACTCGGCTTCTGGCCTGCGAATGGGCGGGCAAGGGCATCAATGTGAACGCCATCGCACCGGG CTATTTCGAGACCAACAACACGCAGGCCCTGCGGGAAGACCCCGAGCGCAGTGCCGCCATTCTCGCCCGCATTCCGGCCG GCCACTGGGGCCAGCCCTCAGAACTGGGTGGGGCGGCGGTGTTCCTTGCCGCGCGTGCCTCCGATTATGTGCATGGCGTG GTGCTGCCCGTGGATGGCGGCTGGCTGGCCCGATAG
Upstream 100 bases:
>100_bases TCGGCACCCGCGCCTACACCTTTATCTGGGGTATGGGCGGCGACAATATCGATTATACGGACATGGACATGGTCGCCATG GACCAGTTGCGGTGAGCGGG
Downstream 100 bases:
>100_bases AGCAACAGGGAGCGCCCGCGCATCCCGCGGGCGCCTTTCCGGAGAAGTGACATGGCGCAGAAGGGCGACGTCTTCGCATT CGCGGGCGAGACGGAGGTAG
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MTSPFDLSGKRAIVTGANTGLGQAIAVALAQAGAGIVAVGRSAMDETGEAVRAAGVAFTEVRADLATLEPIGRIVEEASV GGRVDILVNNAGIIRRADAIDFTEADWDAVMDVNLKSTFFLTQGVARGMLADGKGGKVINIASLLSFQGGIRIPSYTASK SGLAGLTRLLACEWAGKGINVNAIAPGYFETNNTQALREDPERSAAILARIPAGHWGQPSELGGAAVFLAARASDYVHGV VLPVDGGWLAR
Sequences:
>Translated_251_residues MTSPFDLSGKRAIVTGANTGLGQAIAVALAQAGAGIVAVGRSAMDETGEAVRAAGVAFTEVRADLATLEPIGRIVEEASV GGRVDILVNNAGIIRRADAIDFTEADWDAVMDVNLKSTFFLTQGVARGMLADGKGGKVINIASLLSFQGGIRIPSYTASK SGLAGLTRLLACEWAGKGINVNAIAPGYFETNNTQALREDPERSAAILARIPAGHWGQPSELGGAAVFLAARASDYVHGV VLPVDGGWLAR >Mature_250_residues TSPFDLSGKRAIVTGANTGLGQAIAVALAQAGAGIVAVGRSAMDETGEAVRAAGVAFTEVRADLATLEPIGRIVEEASVG GRVDILVNNAGIIRRADAIDFTEADWDAVMDVNLKSTFFLTQGVARGMLADGKGGKVINIASLLSFQGGIRIPSYTASKS GLAGLTRLLACEWAGKGINVNAIAPGYFETNNTQALREDPERSAAILARIPAGHWGQPSELGGAAVFLAARASDYVHGVV LPVDGGWLAR
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=34.1176470588235, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=33.1967213114754, Blast_Score=121, Evalue=6e-28, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=32.5490196078431, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=32.3886639676113, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=31.7269076305221, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=29.296875, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=28.6821705426357, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=29.0076335877863, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=31.4720812182741, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI59889578, Length=172, Percent_Identity=36.6279069767442, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=32.9787234042553, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=33.6633663366337, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=32.5490196078431, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=34.1968911917098, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=28.755364806867, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI224922801, Length=189, Percent_Identity=32.2751322751323, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI225579078, Length=210, Percent_Identity=31.4285714285714, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=59.1269841269841, Blast_Score=294, Evalue=4e-81, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=47.4308300395257, Blast_Score=197, Evalue=7e-52, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=40.3100775193798, Blast_Score=167, Evalue=5e-43, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=36.5853658536585, Blast_Score=139, Evalue=1e-34, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=33.596837944664, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=33.4677419354839, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=34.4262295081967, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.1497975708502, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=29.3877551020408, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789057, Length=117, Percent_Identity=37.6068376068376, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=35.5102040816327, Blast_Score=134, Evalue=6e-32, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=30.7377049180328, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=30.7392996108949, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=29.3650793650794, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.8063241106719, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=31.4393939393939, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=34, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=33.8461538461538, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=34.3511450381679, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=32.6771653543307, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=33.2089552238806, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=32.319391634981, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=31.0606060606061, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=30.3846153846154, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=31.3653136531365, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=32.4626865671642, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=29.8850574712644, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=30.1158301158301, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30.3846153846154, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=30.3703703703704, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=31.640625, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17561272, Length=252, Percent_Identity=28.968253968254, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=29.4573643410853, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17538182, Length=269, Percent_Identity=32.7137546468402, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=29.811320754717, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=30.3370786516854, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=26.5060240963855, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=30.8900523560209, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=25.6916996047431, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17555612, Length=218, Percent_Identity=31.1926605504587, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI86565303, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=29.3193717277487, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=35.2040816326531, Blast_Score=91, Evalue=2e-19, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=34.0080971659919, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=33.6, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=31.3253012048193, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=34.136546184739, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.9317269076305, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=32.2709163346614, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=30.8641975308642, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=36.5079365079365, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=31.1538461538462, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=34, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=28.968253968254, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=30.6878306878307, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=30.6878306878307, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI24649181, Length=211, Percent_Identity=30.8056872037915, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=28.4974093264249, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI28574402, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665247, Length=194, Percent_Identity=31.4432989690722, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI221331216, Length=210, Percent_Identity=31.4285714285714, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=30.4123711340206, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 25858; Mature: 25726
Theoretical pI: Translated: 5.34; Mature: 5.34
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSPFDLSGKRAIVTGANTGLGQAIAVALAQAGAGIVAVGRSAMDETGEAVRAAGVAFTE CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCHHHH VRADLATLEPIGRIVEEASVGGRVDILVNNAGIIRRADAIDFTEADWDAVMDVNLKSTFF HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCEEEECCCCCEEE LTQGVARGMLADGKGGKVINIASLLSFQGGIRIPSYTASKSGLAGLTRLLACEWAGKGIN EHHHHHHCEEECCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE VNAIAPGYFETNNTQALREDPERSAAILARIPAGHWGQPSELGGAAVFLAARASDYVHGV EEEECCCEEECCCCHHHHCCCCHHEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEE VLPVDGGWLAR EEEECCCCCCC >Mature Secondary Structure TSPFDLSGKRAIVTGANTGLGQAIAVALAQAGAGIVAVGRSAMDETGEAVRAAGVAFTE CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCHHHH VRADLATLEPIGRIVEEASVGGRVDILVNNAGIIRRADAIDFTEADWDAVMDVNLKSTFF HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCEEEECCCCCEEE LTQGVARGMLADGKGGKVINIASLLSFQGGIRIPSYTASKSGLAGLTRLLACEWAGKGIN EHHHHHHCEEECCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE VNAIAPGYFETNNTQALREDPERSAAILARIPAGHWGQPSELGGAAVFLAARASDYVHGV EEEECCCEEECCCCHHHHCCCCHHEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEE VLPVDGGWLAR EEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1766386 [H]