Click here to switch to the map view.

The map label for this gene is opdE [H]

Identifier: 158424901

GI number: 158424901

Start: 3783452

End: 3784648

Strand: Reverse

Name: opdE [H]

Synonym: AZC_3277

Alternate gene names: 158424901

Gene position: 3784648-3783452 (Counterclockwise)

Preceding gene: 158424902

Following gene: 158424900

Centisome position: 70.48

GC content: 69.09

Gene sequence:

>1197_bases
ATGCTTACATCCTCCAAGCCGGATCTCGCCGTCGTGCAACGCGGCACCGCCGCCTGGGGCGCGGTGCTCGCGCTCGCCTT
GTGTGCCTTCGCCCTCATCGCCTCCGAATTCATGCCGGTGAGCCTGCTCACGCCCATCTCCGCCGATCTCGGCATCTCCG
AAGGACAGGCCGGACAGGCGATTTCGGTTTCTGGCGCCTTTGCGGTGCTCACCAGCCTGTTCATCGCGTCCCTTGCCGGA
AGCCTCGACCGAAAAGTGCTGTTGCTCGCGCTCACGGGCTTGATGATCGCGTCGGGCGCCATTGTCGCGGCCGCGCCCAA
TTACGCGGTGCTGATGGCCGGGCGTGCGCTGATCGGGGTCGTCATCGGCGGCTTCTGGTCCATGTCCGCCGCCACCGCCA
TGCGTCTGGTCCCTGAAGCGCAGGTGCCTCGCGCGCTCGCGATCCTGAACGGCGGCAATGCCCTCGCGACGGTGGTCGCT
GCGCCCATGGGGAGTTTCCTCGGCGGTCTGATCGGCTGGCGCGGCGCATTCTTCTGCGTCGTCCCCGTAGCCGTTCTGGT
GTTCCTCTGGCTGCTGGCCAGCCTGCCGACGCTGCCGGTGGAGCGGCGGCCTGCCGCCCCCGGTGCGTTCCGGCTGGTGT
GGTGGCCGGTGGTTGGATGGGGCATGGCGGCGGTCAGCCTCTTCTTCATGGGGCAGTTCACCCTGTTCACCTATCTGCGC
CCATTCCTGGAGGCGGTGACGCGCGTGAACGTGCCGACGCTCTCGCTCATTCTGCTGGTCATGGGCGTCACCGGCTTCGT
CGGCACCAGTCTGATCGGGGCTGCACTGAGGCGTAGCCTCTACGGCACGCTCGTCGTCATCCCGGCGCTCATGGGCGGTA
TCGGGCTCGCGCTGACGCTGTTCGGCGGGAGCCCCCTCGCGACGGCGCTCCTGCTCGCCGGCTGGGGCTTCCTCAGCACG
GCGGCGCCTGTCGGCTGGTGGATCTGGCTGTCGCGTACCCTCCCGCAGGATGCGGAGGCGGGTGGCGGGCTCATGGTGGC
GGTCGTCCAGCTCGCCATCACCCTTGGCGCGACGGTCGGCGGCTTGCTGTTCGATCTCCGTGGATACGACGCCACCTTCG
GTACGGCGGTTGTCCTGCTGGTGCTGGCGGCGCTTCTGGCCTGGCGCACGGCGGGCGTCGCGCGCGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
ATCCCAGCTCTGACGCACGTCGGTGCGTGCCGCTCGCCCTTGAACCCGGGTTCGGGGGGCGGGGGACGCGCGCCCCGGGC
GGGACGCGGAACGGACGCTC

Downstream 100 bases:

>100_bases
ACTGAATGGCGGCGGCCGGGGGCACCTCATTGTTGAGCGGTGCTCATAGGCCCATTCCGCCCCGCCGCCCTAATCGCCGT
GCCGACGCAAGGTTAGAGTG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLTSSKPDLAVVQRGTAAWGAVLALALCAFALIASEFMPVSLLTPISADLGISEGQAGQAISVSGAFAVLTSLFIASLAG
SLDRKVLLLALTGLMIASGAIVAAAPNYAVLMAGRALIGVVIGGFWSMSAATAMRLVPEAQVPRALAILNGGNALATVVA
APMGSFLGGLIGWRGAFFCVVPVAVLVFLWLLASLPTLPVERRPAAPGAFRLVWWPVVGWGMAAVSLFFMGQFTLFTYLR
PFLEAVTRVNVPTLSLILLVMGVTGFVGTSLIGAALRRSLYGTLVVIPALMGGIGLALTLFGGSPLATALLLAGWGFLST
AAPVGWWIWLSRTLPQDAEAGGGLMVAVVQLAITLGATVGGLLFDLRGYDATFGTAVVLLVLAALLAWRTAGVARASA

Sequences:

>Translated_398_residues
MLTSSKPDLAVVQRGTAAWGAVLALALCAFALIASEFMPVSLLTPISADLGISEGQAGQAISVSGAFAVLTSLFIASLAG
SLDRKVLLLALTGLMIASGAIVAAAPNYAVLMAGRALIGVVIGGFWSMSAATAMRLVPEAQVPRALAILNGGNALATVVA
APMGSFLGGLIGWRGAFFCVVPVAVLVFLWLLASLPTLPVERRPAAPGAFRLVWWPVVGWGMAAVSLFFMGQFTLFTYLR
PFLEAVTRVNVPTLSLILLVMGVTGFVGTSLIGAALRRSLYGTLVVIPALMGGIGLALTLFGGSPLATALLLAGWGFLST
AAPVGWWIWLSRTLPQDAEAGGGLMVAVVQLAITLGATVGGLLFDLRGYDATFGTAVVLLVLAALLAWRTAGVARASA
>Mature_398_residues
MLTSSKPDLAVVQRGTAAWGAVLALALCAFALIASEFMPVSLLTPISADLGISEGQAGQAISVSGAFAVLTSLFIASLAG
SLDRKVLLLALTGLMIASGAIVAAAPNYAVLMAGRALIGVVIGGFWSMSAATAMRLVPEAQVPRALAILNGGNALATVVA
APMGSFLGGLIGWRGAFFCVVPVAVLVFLWLLASLPTLPVERRPAAPGAFRLVWWPVVGWGMAAVSLFFMGQFTLFTYLR
PFLEAVTRVNVPTLSLILLVMGVTGFVGTSLIGAALRRSLYGTLVVIPALMGGIGLALTLFGGSPLATALLLAGWGFLST
AAPVGWWIWLSRTLPQDAEAGGGLMVAVVQLAITLGATVGGLLFDLRGYDATFGTAVVLLVLAALLAWRTAGVARASA

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=368, Percent_Identity=41.5760869565217, Blast_Score=265, Evalue=5e-72,
Organism=Escherichia coli, GI1787947, Length=295, Percent_Identity=28.135593220339, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787808, Length=235, Percent_Identity=28.5106382978723, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786595, Length=350, Percent_Identity=26, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40777; Mature: 40777

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSSKPDLAVVQRGTAAWGAVLALALCAFALIASEFMPVSLLTPISADLGISEGQAGQA
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCE
ISVSGAFAVLTSLFIASLAGSLDRKVLLLALTGLMIASGAIVAAAPNYAVLMAGRALIGV
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHEEHHHHHHHHH
VIGGFWSMSAATAMRLVPEAQVPRALAILNGGNALATVVAAPMGSFLGGLIGWRGAFFCV
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPVAVLVFLWLLASLPTLPVERRPAAPGAFRLVWWPVVGWGMAAVSLFFMGQFTLFTYLR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLEAVTRVNVPTLSLILLVMGVTGFVGTSLIGAALRRSLYGTLVVIPALMGGIGLALTL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FGGSPLATALLLAGWGFLSTAAPVGWWIWLSRTLPQDAEAGGGLMVAVVQLAITLGATVG
CCCCHHHHHHHHHHCHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GLLFDLRGYDATFGTAVVLLVLAALLAWRTAGVARASA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCC
>Mature Secondary Structure
MLTSSKPDLAVVQRGTAAWGAVLALALCAFALIASEFMPVSLLTPISADLGISEGQAGQA
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCE
ISVSGAFAVLTSLFIASLAGSLDRKVLLLALTGLMIASGAIVAAAPNYAVLMAGRALIGV
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHEEHHHHHHHHH
VIGGFWSMSAATAMRLVPEAQVPRALAILNGGNALATVVAAPMGSFLGGLIGWRGAFFCV
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPVAVLVFLWLLASLPTLPVERRPAAPGAFRLVWWPVVGWGMAAVSLFFMGQFTLFTYLR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLEAVTRVNVPTLSLILLVMGVTGFVGTSLIGAALRRSLYGTLVVIPALMGGIGLALTL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FGGSPLATALLLAGWGFLSTAAPVGWWIWLSRTLPQDAEAGGGLMVAVVQLAITLGATVG
CCCCHHHHHHHHHHCHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GLLFDLRGYDATFGTAVVLLVLAALLAWRTAGVARASA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]