Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 158424816

GI number: 158424816

Start: 3651484

End: 3652404

Strand: Direct

Name: livH [H]

Synonym: AZC_3192

Alternate gene names: 158424816

Gene position: 3651484-3652404 (Clockwise)

Preceding gene: 158424815

Following gene: 158424817

Centisome position: 68.0

GC content: 68.4

Gene sequence:

>921_bases
ATGACCACGGCACTGTTCGTCTCCCAGTTGCTGAACGGGCTACAGTTCGGCGTGATCCTCTTCCTCGTCGCCGCCGGTCT
GACGCTCGTGTTCGGGGTGATGGACTTCATCAACCTCGCCCACGGCGTCCAGTACATGATCGGCGCCTATCTGGTGGCCG
TCGCCACCGCCTCCACGGGCAACTTCGCCATCGGCCTGATCACCGGCCTCTTCGGCGCTCTGGTGCTGGGCGTCGTGCTG
GAGACGCTGGTGTTCCGGCATCTCACGCGGAAGGATCACCTGGATCAGGTGCTCGCCACCTTCGGCGTCATCCTGGTGGT
CACGGAACTGGCGCGGATCGTGTTCGGCGCGGCGCCCATCGCCTTCCCCATTCCGGCCGCGCTCAGCGGCGCGGTGACGC
TGATGCCGGGGCTCGTCTATCCGGTCTGGCGCCTTGTGATCCTCGCTGCCGGCGTGGGCGTCGCCGTGCTGCTCTGGTAT
CTCGTCACGCGCACTCGGCTCGGCATGCTGGTGCGGGCGGGATCGACCCATCCGCAGACCGTCGCCGCGCTGGGCGTGGA
TGTGGACCGCCTGTTCAGGGCCGTCTTCGCCTTCGGCGCCGTGCTCGCGGGTCTCGCCGGCGCCATGGCAGGCCCCCTCG
TCTCGGTGGAACCGACCATGGGCGACCGCATCCTCATCGTCGCCTTCGTGGTCATCGTCATCGGCGGCATCGGCTCCATC
AAGGGGGCCTTCGTCGCGGCGATCATCGTGGGGCTGGTGGATACGCTCGGGCGCGCCTTTGCGCCGGAGCTTCTGAAACT
GCTCATCGGGCGCTCGGCCGCAGCGGCGGCCGGCCCGGCCCTCTCCTCCATGGCGATCTACCTGCTGATGGCCGCGGTCC
TGAGCTTCCGTCCGACCGGCCTGTTCGGCGGGAGATCGTGA

Upstream 100 bases:

>100_bases
GCCCCCTGAAGTGATCCGCCCCGCCGGCCGGGGGGGATGGCAGGAGCGCCCTTCTCCGGCCGGCGCTGCCAGATCGCAAG
TTCCGACGCCGAGAGGGGCC

Downstream 100 bases:

>100_bases
TGACGGTCCCGTCTTTCGTGAAAAACCCGGCACTGGCGACCGTCGCGGCCTTCCTTCTGCTCCTCGCTCTCGCCCATGGG
CTCGGCTTCTCCCATGGCGC

Product: ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTTALFVSQLLNGLQFGVILFLVAAGLTLVFGVMDFINLAHGVQYMIGAYLVAVATASTGNFAIGLITGLFGALVLGVVL
ETLVFRHLTRKDHLDQVLATFGVILVVTELARIVFGAAPIAFPIPAALSGAVTLMPGLVYPVWRLVILAAGVGVAVLLWY
LVTRTRLGMLVRAGSTHPQTVAALGVDVDRLFRAVFAFGAVLAGLAGAMAGPLVSVEPTMGDRILIVAFVVIVIGGIGSI
KGAFVAAIIVGLVDTLGRAFAPELLKLLIGRSAAAAAGPALSSMAIYLLMAAVLSFRPTGLFGGRS

Sequences:

>Translated_306_residues
MTTALFVSQLLNGLQFGVILFLVAAGLTLVFGVMDFINLAHGVQYMIGAYLVAVATASTGNFAIGLITGLFGALVLGVVL
ETLVFRHLTRKDHLDQVLATFGVILVVTELARIVFGAAPIAFPIPAALSGAVTLMPGLVYPVWRLVILAAGVGVAVLLWY
LVTRTRLGMLVRAGSTHPQTVAALGVDVDRLFRAVFAFGAVLAGLAGAMAGPLVSVEPTMGDRILIVAFVVIVIGGIGSI
KGAFVAAIIVGLVDTLGRAFAPELLKLLIGRSAAAAAGPALSSMAIYLLMAAVLSFRPTGLFGGRS
>Mature_305_residues
TTALFVSQLLNGLQFGVILFLVAAGLTLVFGVMDFINLAHGVQYMIGAYLVAVATASTGNFAIGLITGLFGALVLGVVLE
TLVFRHLTRKDHLDQVLATFGVILVVTELARIVFGAAPIAFPIPAALSGAVTLMPGLVYPVWRLVILAAGVGVAVLLWYL
VTRTRLGMLVRAGSTHPQTVAALGVDVDRLFRAVFAFGAVLAGLAGAMAGPLVSVEPTMGDRILIVAFVVIVIGGIGSIK
GAFVAAIIVGLVDTLGRAFAPELLKLLIGRSAAAAAGPALSSMAIYLLMAAVLSFRPTGLFGGRS

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=281, Percent_Identity=27.0462633451957, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 31538; Mature: 31406

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTALFVSQLLNGLQFGVILFLVAAGLTLVFGVMDFINLAHGVQYMIGAYLVAVATASTG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NFAIGLITGLFGALVLGVVLETLVFRHLTRKDHLDQVLATFGVILVVTELARIVFGAAPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AFPIPAALSGAVTLMPGLVYPVWRLVILAAGVGVAVLLWYLVTRTRLGMLVRAGSTHPQT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VAALGVDVDRLFRAVFAFGAVLAGLAGAMAGPLVSVEPTMGDRILIVAFVVIVIGGIGSI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCHH
KGAFVAAIIVGLVDTLGRAFAPELLKLLIGRSAAAAAGPALSSMAIYLLMAAVLSFRPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCC
LFGGRS
CCCCCC
>Mature Secondary Structure 
TTALFVSQLLNGLQFGVILFLVAAGLTLVFGVMDFINLAHGVQYMIGAYLVAVATASTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]