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The map label for this gene is aatA [H]

Identifier: 158424756

GI number: 158424756

Start: 3589299

End: 3590501

Strand: Direct

Name: aatA [H]

Synonym: AZC_3132

Alternate gene names: 158424756

Gene position: 3589299-3590501 (Clockwise)

Preceding gene: 158424753

Following gene: 158424757

Centisome position: 66.84

GC content: 64.51

Gene sequence:

>1203_bases
ATGAGCCTTCTCTCGTCCGCCCTCAAGCGTATCAAGCCCTCGCCCACCATCGCCATTTCCAACAAGGCGCGTGAGCTGAA
GGCCACCGGACGTGACATCATCGCCCTCAGCGCCGGCGAGCCCGATTTCGACACGCCGGACAACATCAAGGAAGCGGCCA
TCGCGGCCATCCGCCGGGGCGAGACCAAGTATACCGCCGTGGATGGCATGCCCGAGCTGAAGGCGGCCATCTGCCGCAAG
TTCAAGCGCGAGAACGGTCTCGACTACAAGCCCTCGCAGGTCACGGTCGGCACCGGCGGCAAGCAGGTGCTGTTCAATGC
CCTGGTCGCGACGGTGGACGCCGGCGACGAGGTGCTGATTCCCGCCCCCTTCTGGGTGAGCTATCCGGACATCGTGGAAT
TCTGCGGCGGCAAGCCCGTCTCCGTGCCGACCACGATCGAGGACAATTTCAAGCTGCGTCCGGACGTGCTGGAAGCCCAC
ATCACGCCGAAGACCAAGTGGCTGATCTTCAACTCCCCGTCCAATCCGTCGGGCGCCGCCTACAGCTTCGATGAGCTGAA
GGCCCTCACCGACGTGCTTCTGCGCCACCCGCACGTCATGATCCTCACGGACGACATGTACGAGCACCTCGTCTATGACG
ACTTCAAGTTCGTCACCCCGGCGCAGGTGGAGCCGCAGCTCTACGACCGCACGCTGACCATGAACGGCGTGTCCAAGGCC
TATTGCATGACCGGCTGGCGCATCGGCTATGCGGCCGGCCCCGAGGCCCTGATCAAGGCCATCGGCACGCTGCAGTCGCA
GTCCACCTCCAACCCCTCCTCCATCGCCCAGTGGGCGGCGCTCGAGGCGCTGGATGGTCCGCAGGACTTCATCGCCGAGA
ACAACAAGGTGTTCAAGGAGCGCCGCGATCTCGTGGTCTCCATGCTGAACCAGGCCAAGGGTCTGCATTGCCCGAAGCCG
GAAGGCGCCTTCTACGTGTTCCCGTCCTGCGCCGGGACCATCGGCAAGAAGACCCCCGAGGGCAAGGTCATCGCCACGGA
CGAGGATTTCGCGACCGAACTCCTGAGCGCAGAAGGCGTTGCGGTGGTCCATGGCTCGGCCTTCGGCCTCGGCCCGGCCT
TCCGTATCTCCTATGCGACGGCGACCTCGGATCTCGAGGAAGCCTGCCGCCGCATCCAGCGCTTCTGTGGCGCATTGGTC
TGA

Upstream 100 bases:

>100_bases
CCCGGCAAGGCTATATGGCGCGCCGGGATTTTCGTGTCACCTTCGCGTCGCCCCAGCGCAGAGAACGCGGCTGGAGCGAT
GTGCCCGGAGCCTTACGGCC

Downstream 100 bases:

>100_bases
GTTCCAGAAAAAAGGAACCTGGGGCCCTCGGGCGCGTTGGCGAACGGTTGAGACCGAGCTAAGGCTTGCCCACCCGCAAC
GGGTGGGTAACCCTCTGGGC

Product: aspartate aminotransferase A

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSLLSSALKRIKPSPTIAISNKARELKATGRDIIALSAGEPDFDTPDNIKEAAIAAIRRGETKYTAVDGMPELKAAICRK
FKRENGLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLIPAPFWVSYPDIVEFCGGKPVSVPTTIEDNFKLRPDVLEAH
ITPKTKWLIFNSPSNPSGAAYSFDELKALTDVLLRHPHVMILTDDMYEHLVYDDFKFVTPAQVEPQLYDRTLTMNGVSKA
YCMTGWRIGYAAGPEALIKAIGTLQSQSTSNPSSIAQWAALEALDGPQDFIAENNKVFKERRDLVVSMLNQAKGLHCPKP
EGAFYVFPSCAGTIGKKTPEGKVIATDEDFATELLSAEGVAVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGALV

Sequences:

>Translated_400_residues
MSLLSSALKRIKPSPTIAISNKARELKATGRDIIALSAGEPDFDTPDNIKEAAIAAIRRGETKYTAVDGMPELKAAICRK
FKRENGLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLIPAPFWVSYPDIVEFCGGKPVSVPTTIEDNFKLRPDVLEAH
ITPKTKWLIFNSPSNPSGAAYSFDELKALTDVLLRHPHVMILTDDMYEHLVYDDFKFVTPAQVEPQLYDRTLTMNGVSKA
YCMTGWRIGYAAGPEALIKAIGTLQSQSTSNPSSIAQWAALEALDGPQDFIAENNKVFKERRDLVVSMLNQAKGLHCPKP
EGAFYVFPSCAGTIGKKTPEGKVIATDEDFATELLSAEGVAVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGALV
>Mature_399_residues
SLLSSALKRIKPSPTIAISNKARELKATGRDIIALSAGEPDFDTPDNIKEAAIAAIRRGETKYTAVDGMPELKAAICRKF
KRENGLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLIPAPFWVSYPDIVEFCGGKPVSVPTTIEDNFKLRPDVLEAHI
TPKTKWLIFNSPSNPSGAAYSFDELKALTDVLLRHPHVMILTDDMYEHLVYDDFKFVTPAQVEPQLYDRTLTMNGVSKAY
CMTGWRIGYAAGPEALIKAIGTLQSQSTSNPSSIAQWAALEALDGPQDFIAENNKVFKERRDLVVSMLNQAKGLHCPKPE
GAFYVFPSCAGTIGKKTPEGKVIATDEDFATELLSAEGVAVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGALV

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=365, Percent_Identity=29.3150684931507, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI169881279, Length=365, Percent_Identity=29.3150684931507, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI56713254, Length=315, Percent_Identity=30.7936507936508, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI56713256, Length=315, Percent_Identity=30.7936507936508, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI169881281, Length=271, Percent_Identity=26.9372693726937, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4507369, Length=401, Percent_Identity=25.6857855361596, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=27.5510204081633, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788722, Length=350, Percent_Identity=31.1428571428571, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=27.0557029177719, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=362, Percent_Identity=27.9005524861878, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=362, Percent_Identity=27.9005524861878, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=336, Percent_Identity=25.297619047619, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=24.6073298429319, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=312, Percent_Identity=28.8461538461538, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=368, Percent_Identity=24.4565217391304, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=26.9349845201238, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=26.9349845201238, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=26.9349845201238, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=26.9349845201238, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI18859735, Length=385, Percent_Identity=25.974025974026, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24641770, Length=408, Percent_Identity=25.2450980392157, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641760, Length=408, Percent_Identity=25.2450980392157, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641768, Length=408, Percent_Identity=25.2450980392157, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641766, Length=408, Percent_Identity=25.2450980392157, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641764, Length=408, Percent_Identity=25.2450980392157, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45551451, Length=408, Percent_Identity=25.2450980392157, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43423; Mature: 43292

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLSSALKRIKPSPTIAISNKARELKATGRDIIALSAGEPDFDTPDNIKEAAIAAIRRG
CHHHHHHHHHCCCCCCEEECCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ETKYTAVDGMPELKAAICRKFKRENGLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLI
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPFWVSYPDIVEFCGGKPVSVPTTIEDNFKLRPDVLEAHITPKTKWLIFNSPSNPSGAA
CCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCHHHHEECCCCEEEEEEECCCCCCCCC
YSFDELKALTDVLLRHPHVMILTDDMYEHLVYDDFKFVTPAQVEPQLYDRTLTMNGVSKA
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCCCCCCCHHHHCCEEEECCCCHH
YCMTGWRIGYAAGPEALIKAIGTLQSQSTSNPSSIAQWAALEALDGPQDFIAENNKVFKE
HHHCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
RRDLVVSMLNQAKGLHCPKPEGAFYVFPSCAGTIGKKTPEGKVIATDEDFATELLSAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCE
AVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGALV
EEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLLSSALKRIKPSPTIAISNKARELKATGRDIIALSAGEPDFDTPDNIKEAAIAAIRRG
HHHHHHHHHCCCCCCEEECCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ETKYTAVDGMPELKAAICRKFKRENGLDYKPSQVTVGTGGKQVLFNALVATVDAGDEVLI
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPFWVSYPDIVEFCGGKPVSVPTTIEDNFKLRPDVLEAHITPKTKWLIFNSPSNPSGAA
CCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCHHHHEECCCCEEEEEEECCCCCCCCC
YSFDELKALTDVLLRHPHVMILTDDMYEHLVYDDFKFVTPAQVEPQLYDRTLTMNGVSKA
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCCCCCCCHHHHCCEEEECCCCHH
YCMTGWRIGYAAGPEALIKAIGTLQSQSTSNPSSIAQWAALEALDGPQDFIAENNKVFKE
HHHCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
RRDLVVSMLNQAKGLHCPKPEGAFYVFPSCAGTIGKKTPEGKVIATDEDFATELLSAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCE
AVVHGSAFGLGPAFRISYATATSDLEEACRRIQRFCGALV
EEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]