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The map label for this gene is ntrY

Identifier: 158424708

GI number: 158424708

Start: 3526829

End: 3529144

Strand: Reverse

Name: ntrY

Synonym: AZC_3084

Alternate gene names: 158424708

Gene position: 3529144-3526829 (Counterclockwise)

Preceding gene: 158424709

Following gene: 158424707

Centisome position: 65.72

GC content: 67.57

Gene sequence:

>2316_bases
ATGACGCAAGCCGCGTTTGACCAGGCTTCGGACAACGGACCCATGACGCCGTCCGGCTCGTCCTTCGGCCTGTTCGCCCC
GGCAGTGGTGCTGCTCGCCCTCATCTCGGCTCTCGCCACCTTCCTCATCCTCATGGGCCTCACCCCCGTGGTGCCGACCC
ATCAGGTGGTCATCAGCGTGCTGCTGGTGAATGCGGCAGCGGTGCTGATCCTCAGCGCCATGGTCGGCCGCGAGATCTGG
CGCATCGCCAAGGCGCGGGCGCGCGGGCGCGCCGCCGCCCGGCTGCACATCCGCATTGTCGGCCTGTTCGCGGTGGTCTC
CGTGGTGCCGGCCATCCTCGTGGCGGTGGTGGCTAGCCTGACGCTCGACCGCGGGCTCGACCGCTGGTTCTCCATGCGCA
CGCAGGAGATCGTGGCGAGTTCCGTCTCCGTCGCCCAGACCTATGTGCGCGAGCACGCCCTGAACATCCGGGGCGACATC
CTCGCCATGAGCGCGGACCTGACGCGGCTGAAGTCGGTCTATGAAGGGGACCGCTCGCGCTTCAACCAGATCCTCACTGC
GCAGGCGGCGCTGCGGAACCTGCCGGGCGCCATGCTGATCCGCCGCGACCTCTCGGTGGTGGAGCGGGCCAACGTCAACA
TCGGCCGCGAATTCATCGTCCCCGCCAACCTCGCCATTGGGGATGCGACGCCGGATCAGCCGGTGATCTATCTGCCCAAT
GACGCGGACTATGTGGCCGCCGTGGTGCCGCTCAAGGACTATGACGACCTCTATCTCTACGTGGCCCGCCTCATCGATCC
GCGCGTCATCGGCTATCTGAAGACCACGCAGGAGACGCTGGCCGACTATCGGTCGCTGGAGGAGCGGCGCTTCGGCGTGC
AGGTGGCCTTCGCGCTCATGTATGCGGTCATCACGCTCATCGTGCTGCTCTCCGCGGTCTGGCTCGGCCTCAACTTCTCC
AAGTGGCTGGTGGCGCCCATCCGCCGCCTCATGTCGGCAGCCGACCATGTGGCGGAAGGCAATCTCGACGTACGCGTGCC
CATCTATCGGGCCGAAGGCGATCTCGCCTCGCTCGCCGAGACCTTCAACAAGATGACCCACGAGCTGCGCAGCCAGCGCG
AGGCCATCCTCACCGCCCGCGACCAGATCGACAGCCGCCGCCGCTTCACGGAAGCCGTGCTTTCCGGTGTCGGCGCGGGC
GTCATCGGCCTCGATTCGCAGGAGCGCATCACCATCCTCAACCGCTCGGCCGAGCGCCTTTTGGGGCTGTCGGAGGTGGA
GGCCCTGCACCGGCATCTCGCCGAGGTGGTGCCGGAGACGGCGGGCCTCCTGGAAGAGGCCGAGCATGCGCGGCAGCGTA
GCGTTCAGGGCAACATCACGCTCACCCGCGACGGGCGTGAGCGCGTCTTCGCGGTCCGTGTCACCACCGAGCAATCGCCC
GAGGCCGAGCATGGCTGGGTGGTGACGCTCGACGACATCACCGAACTCATCTCGGCCCAGCGCACCTCTGCCTGGGCGGA
TGTGGCCCGGCGCATCGCCCACGAGATCAAGAACCCGCTCACCCCCATCCAGCTCTCCGCCGAGCGGCTCAAGCGCAAGT
TCGGCCGGCACGTGACGCAGGATCGGGAGATCTTCGACCAGTGCACCGACACCATCATCCGTCAGGTGGGCGACATCGGC
CGGATGGTGGACGAGTTCTCCTCCTTCGCCCGGATGCCCAAGCCCGTCGTGGACAGCCAGGACATGTCGGAGATCATCCG
CCAGACGGTGTTCCTCATGCGGGTGGGACATCCCGAGGTGGTGTTTGATTCCGAGGTGCCGCCCGCTATGCCCGCGCGCT
TCGACCGCCGCCTCGTTTCCCAAGCCTTAACGAACATCCTCAAGAACGCTGCCGAGGCCATCGAGGCCGTTCCGCCGGAC
GTACGCGGCCAAGGCCGCATCCGCGTCAGCGCCAATCGGGTGGGTGAGGATCTGGTGATCGACATCATCGACAACGGCAC
CGGCCTGCCGCAGGAGAGCCGGAACCGTCTTCTGGAACCCTATGTGACGACGCGCGAAAAGGGCACGGGCCTCGGCCTTG
CCATCGTGGGGAAGATCATGGAGGAGCACGGCGGCGGCATCGAGCTGAACGACGCGCCCGAGGGGCGCGGCGCGTGGATC
CGTCTCACCCTCAAGGCCGAGGGACCGAAGGCGGAACCGACCGATGCCTCAACCAAGGCGACCGGGGCTGCCACGCCCGC
GGCGCCCGCCGCTTCCGCCATGGCCCGCGATGCGGCTGCCGATTCCGCCGCGCGCGGCAAGAACGAGAGGACCTGA

Upstream 100 bases:

>100_bases
ACGACTCAGGGGGCTGCGGGCCGACCGCATGCCCCTGACGACGGCGCAACAGCCGCAGGCCCGGACGACCGGCCCCCGCG
TGCCAGGAGTGGCGTGACAC

Downstream 100 bases:

>100_bases
TCCATGGCCCATGACATCCTGATCGTCGATGACGAGCCCGACATCAGCGGCCTCGTCGCCGGCATCCTGGAGGACGAGGG
CTATTCCGCCCGCACCGCCC

Product: nitrogen regulation protein ntrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 770

Protein sequence:

>771_residues
MTQAAFDQASDNGPMTPSGSSFGLFAPAVVLLALISALATFLILMGLTPVVPTHQVVISVLLVNAAAVLILSAMVGREIW
RIAKARARGRAAARLHIRIVGLFAVVSVVPAILVAVVASLTLDRGLDRWFSMRTQEIVASSVSVAQTYVREHALNIRGDI
LAMSADLTRLKSVYEGDRSRFNQILTAQAALRNLPGAMLIRRDLSVVERANVNIGREFIVPANLAIGDATPDQPVIYLPN
DADYVAAVVPLKDYDDLYLYVARLIDPRVIGYLKTTQETLADYRSLEERRFGVQVAFALMYAVITLIVLLSAVWLGLNFS
KWLVAPIRRLMSAADHVAEGNLDVRVPIYRAEGDLASLAETFNKMTHELRSQREAILTARDQIDSRRRFTEAVLSGVGAG
VIGLDSQERITILNRSAERLLGLSEVEALHRHLAEVVPETAGLLEEAEHARQRSVQGNITLTRDGRERVFAVRVTTEQSP
EAEHGWVVTLDDITELISAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKFGRHVTQDREIFDQCTDTIIRQVGDIG
RMVDEFSSFARMPKPVVDSQDMSEIIRQTVFLMRVGHPEVVFDSEVPPAMPARFDRRLVSQALTNILKNAAEAIEAVPPD
VRGQGRIRVSANRVGEDLVIDIIDNGTGLPQESRNRLLEPYVTTREKGTGLGLAIVGKIMEEHGGGIELNDAPEGRGAWI
RLTLKAEGPKAEPTDASTKATGAATPAAPAASAMARDAAADSAARGKNERT

Sequences:

>Translated_771_residues
MTQAAFDQASDNGPMTPSGSSFGLFAPAVVLLALISALATFLILMGLTPVVPTHQVVISVLLVNAAAVLILSAMVGREIW
RIAKARARGRAAARLHIRIVGLFAVVSVVPAILVAVVASLTLDRGLDRWFSMRTQEIVASSVSVAQTYVREHALNIRGDI
LAMSADLTRLKSVYEGDRSRFNQILTAQAALRNLPGAMLIRRDLSVVERANVNIGREFIVPANLAIGDATPDQPVIYLPN
DADYVAAVVPLKDYDDLYLYVARLIDPRVIGYLKTTQETLADYRSLEERRFGVQVAFALMYAVITLIVLLSAVWLGLNFS
KWLVAPIRRLMSAADHVAEGNLDVRVPIYRAEGDLASLAETFNKMTHELRSQREAILTARDQIDSRRRFTEAVLSGVGAG
VIGLDSQERITILNRSAERLLGLSEVEALHRHLAEVVPETAGLLEEAEHARQRSVQGNITLTRDGRERVFAVRVTTEQSP
EAEHGWVVTLDDITELISAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKFGRHVTQDREIFDQCTDTIIRQVGDIG
RMVDEFSSFARMPKPVVDSQDMSEIIRQTVFLMRVGHPEVVFDSEVPPAMPARFDRRLVSQALTNILKNAAEAIEAVPPD
VRGQGRIRVSANRVGEDLVIDIIDNGTGLPQESRNRLLEPYVTTREKGTGLGLAIVGKIMEEHGGGIELNDAPEGRGAWI
RLTLKAEGPKAEPTDASTKATGAATPAAPAASAMARDAAADSAARGKNERT
>Mature_770_residues
TQAAFDQASDNGPMTPSGSSFGLFAPAVVLLALISALATFLILMGLTPVVPTHQVVISVLLVNAAAVLILSAMVGREIWR
IAKARARGRAAARLHIRIVGLFAVVSVVPAILVAVVASLTLDRGLDRWFSMRTQEIVASSVSVAQTYVREHALNIRGDIL
AMSADLTRLKSVYEGDRSRFNQILTAQAALRNLPGAMLIRRDLSVVERANVNIGREFIVPANLAIGDATPDQPVIYLPND
ADYVAAVVPLKDYDDLYLYVARLIDPRVIGYLKTTQETLADYRSLEERRFGVQVAFALMYAVITLIVLLSAVWLGLNFSK
WLVAPIRRLMSAADHVAEGNLDVRVPIYRAEGDLASLAETFNKMTHELRSQREAILTARDQIDSRRRFTEAVLSGVGAGV
IGLDSQERITILNRSAERLLGLSEVEALHRHLAEVVPETAGLLEEAEHARQRSVQGNITLTRDGRERVFAVRVTTEQSPE
AEHGWVVTLDDITELISAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKFGRHVTQDREIFDQCTDTIIRQVGDIGR
MVDEFSSFARMPKPVVDSQDMSEIIRQTVFLMRVGHPEVVFDSEVPPAMPARFDRRLVSQALTNILKNAAEAIEAVPPDV
RGQGRIRVSANRVGEDLVIDIIDNGTGLPQESRNRLLEPYVTTREKGTGLGLAIVGKIMEEHGGGIELNDAPEGRGAWIR
LTLKAEGPKAEPTDASTKATGAATPAAPAASAMARDAAADSAARGKNERT

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain

Homologues:

Organism=Escherichia coli, GI1788549, Length=420, Percent_Identity=24.7619047619048, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=27.7551020408163, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790300, Length=338, Percent_Identity=26.0355029585799, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=439, Percent_Identity=24.8291571753986, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=26.7543859649123, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTRY_AZOC5 (Q04850)

Other databases:

- EMBL:   X63841
- EMBL:   AP009384
- PIR:   S18624
- RefSeq:   YP_001526000.1
- ProteinModelPortal:   Q04850
- GeneID:   5690261
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_3084
- HOGENOM:   HBG311288
- OMA:   VAITPAI
- ProtClustDB:   CLSK911226
- BioCyc:   ACAU438753:AZC_3084-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232
- Gene3D:   G3DSA:3.30.565.10
- PIRSF:   PIRSF037532
- PRINTS:   PR00344
- SMART:   SM00304
- SMART:   SM00387
- SMART:   SM00388
- SMART:   SM00091
- TIGRFAMs:   TIGR00229

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 84265; Mature: 84134

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN; PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x215ba500)-; HASH(0x21baf6b4)-; HASH(0x22383354)-; HASH(0x223449a4)-;

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAAFDQASDNGPMTPSGSSFGLFAPAVVLLALISALATFLILMGLTPVVPTHQVVISV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LLVNAAAVLILSAMVGREIWRIAKARARGRAAARLHIRIVGLFAVVSVVPAILVAVVASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLDRGLDRWFSMRTQEIVASSVSVAQTYVREHALNIRGDILAMSADLTRLKSVYEGDRSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
FNQILTAQAALRNLPGAMLIRRDLSVVERANVNIGREFIVPANLAIGDATPDQPVIYLPN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCCCCCEEECCC
DADYVAAVVPLKDYDDLYLYVARLIDPRVIGYLKTTQETLADYRSLEERRFGVQVAFALM
CCCEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAVITLIVLLSAVWLGLNFSKWLVAPIRRLMSAADHVAEGNLDVRVPIYRAEGDLASLAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHH
TFNKMTHELRSQREAILTARDQIDSRRRFTEAVLSGVGAGVIGLDSQERITILNRSAERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCHHHH
LGLSEVEALHRHLAEVVPETAGLLEEAEHARQRSVQGNITLTRDGRERVFAVRVTTEQSP
HCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCC
EAEHGWVVTLDDITELISAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKFGRHVTQ
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCH
DREIFDQCTDTIIRQVGDIGRMVDEFSSFARMPKPVVDSQDMSEIIRQTVFLMRVGHPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
VFDSEVPPAMPARFDRRLVSQALTNILKNAAEAIEAVPPDVRGQGRIRVSANRVGEDLVI
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCEEE
DIIDNGTGLPQESRNRLLEPYVTTREKGTGLGLAIVGKIMEEHGGGIELNDAPEGRGAWI
EEECCCCCCCHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCEE
RLTLKAEGPKAEPTDASTKATGAATPAAPAASAMARDAAADSAARGKNERT
EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TQAAFDQASDNGPMTPSGSSFGLFAPAVVLLALISALATFLILMGLTPVVPTHQVVISV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LLVNAAAVLILSAMVGREIWRIAKARARGRAAARLHIRIVGLFAVVSVVPAILVAVVASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLDRGLDRWFSMRTQEIVASSVSVAQTYVREHALNIRGDILAMSADLTRLKSVYEGDRSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
FNQILTAQAALRNLPGAMLIRRDLSVVERANVNIGREFIVPANLAIGDATPDQPVIYLPN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCCCCCEEECCC
DADYVAAVVPLKDYDDLYLYVARLIDPRVIGYLKTTQETLADYRSLEERRFGVQVAFALM
CCCEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAVITLIVLLSAVWLGLNFSKWLVAPIRRLMSAADHVAEGNLDVRVPIYRAEGDLASLAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHH
TFNKMTHELRSQREAILTARDQIDSRRRFTEAVLSGVGAGVIGLDSQERITILNRSAERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCHHHH
LGLSEVEALHRHLAEVVPETAGLLEEAEHARQRSVQGNITLTRDGRERVFAVRVTTEQSP
HCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCC
EAEHGWVVTLDDITELISAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKFGRHVTQ
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCH
DREIFDQCTDTIIRQVGDIGRMVDEFSSFARMPKPVVDSQDMSEIIRQTVFLMRVGHPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
VFDSEVPPAMPARFDRRLVSQALTNILKNAAEAIEAVPPDVRGQGRIRVSANRVGEDLVI
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCEEE
DIIDNGTGLPQESRNRLLEPYVTTREKGTGLGLAIVGKIMEEHGGGIELNDAPEGRGAWI
EEECCCCCCCHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCEE
RLTLKAEGPKAEPTDASTKATGAATPAAPAASAMARDAAADSAARGKNERT
EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370