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The map label for this gene is aroQ

Identifier: 158424697

GI number: 158424697

Start: 3513749

End: 3514192

Strand: Direct

Name: aroQ

Synonym: AZC_3073

Alternate gene names: 158424697

Gene position: 3513749-3514192 (Clockwise)

Preceding gene: 158424696

Following gene: 158424698

Centisome position: 65.44

GC content: 68.47

Gene sequence:

>444_bases
ATGTCCGACACCATCCACGTCCTCAACGGACCCAATCTGAACCTCCTCGGCACCCGCGAGCCCGGCATCTACGGTGCCGC
GACGCTGGCCGACGTTGAGGCGCTCTGCCGCACGACCGCGGCCCAGCACGGGCTCGAGCTCGTCTTCCGCCAGAGCAATC
ACGAAGGCGATCTGGTGGACTGGATCCAGGCTGCGGCAGGCTCCGTCGGCGTGGTCCTGAATGCCGGCGCCTATACCCAC
ACCTCCGTCGCGTTGCGCGATGCCATTGCCGGCACCGGCGTTCCCGCCGTCGAGGTGCATCTGTCGAACGTGTTCGCCCG
CGAACCCTTCCGTCACCATTCCTATCTCTCGCCGGTGGTGCGGGGCGTGATCTGCGGCTTCGGGCCCCAGAGCTACGTCC
TCGGCATCACGGCGCTCGCCACAACCCGGCCGGCGCGCCCCTGA

Upstream 100 bases:

>100_bases
GGTCTGGTGAATGGGGTGAGATGGCGTCTTTCCTTGCGACGCAACGCCCCCTATAACCGCGCGGGCCCGGACGCTGCCGG
GTCGCAGCTGAACCGTCAGG

Downstream 100 bases:

>100_bases
GCGCGGCCCTCACCCTTCAGGAGCTCATGCGTGGCTGAACCCGCGTACGTGCAGGATGAAATGAAAAACTCCAAGACCCC
CATCGATACCGACGTCATCC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSDTIHVLNGPNLNLLGTREPGIYGAATLADVEALCRTTAAQHGLELVFRQSNHEGDLVDWIQAAAGSVGVVLNAGAYTH
TSVALRDAIAGTGVPAVEVHLSNVFAREPFRHHSYLSPVVRGVICGFGPQSYVLGITALATTRPARP

Sequences:

>Translated_147_residues
MSDTIHVLNGPNLNLLGTREPGIYGAATLADVEALCRTTAAQHGLELVFRQSNHEGDLVDWIQAAAGSVGVVLNAGAYTH
TSVALRDAIAGTGVPAVEVHLSNVFAREPFRHHSYLSPVVRGVICGFGPQSYVLGITALATTRPARP
>Mature_146_residues
SDTIHVLNGPNLNLLGTREPGIYGAATLADVEALCRTTAAQHGLELVFRQSNHEGDLVDWIQAAAGSVGVVLNAGAYTHT
SVALRDAIAGTGVPAVEVHLSNVFAREPFRHHSYLSPVVRGVICGFGPQSYVLGITALATTRPARP

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_AZOC5 (A8IBI0)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001525989.1
- ProteinModelPortal:   A8IBI0
- SMR:   A8IBI0
- GeneID:   5691225
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_3073
- HOGENOM:   HBG284657
- OMA:   GWLHEAA
- ProtClustDB:   PRK05395
- BioCyc:   ACAU438753:AZC_3073-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15451; Mature: 15319

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTIHVLNGPNLNLLGTREPGIYGAATLADVEALCRTTAAQHGLELVFRQSNHEGDLVD
CCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHH
WIQAAAGSVGVVLNAGAYTHTSVALRDAIAGTGVPAVEVHLSNVFAREPFRHHSYLSPVV
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHHH
RGVICGFGPQSYVLGITALATTRPARP
HHHHHCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDTIHVLNGPNLNLLGTREPGIYGAATLADVEALCRTTAAQHGLELVFRQSNHEGDLVD
CCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHH
WIQAAAGSVGVVLNAGAYTHTSVALRDAIAGTGVPAVEVHLSNVFAREPFRHHSYLSPVV
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHHH
RGVICGFGPQSYVLGITALATTRPARP
HHHHHCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA