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The map label for this gene is braE [H]

Identifier: 158424626

GI number: 158424626

Start: 3432812

End: 3433696

Strand: Direct

Name: braE [H]

Synonym: AZC_3002

Alternate gene names: 158424626

Gene position: 3432812-3433696 (Clockwise)

Preceding gene: 158424625

Following gene: 158424627

Centisome position: 63.93

GC content: 65.54

Gene sequence:

>885_bases
ATGGACGCCTATCTCATCGCCATCGCCATCATCGGCGCGCTCTACGTGCTGCTGGCCCTGGGGCTGAACCTCCAGTACGG
CCTCACCGGCATCGTCAATTTCGGCCATGTGGGCTTCTTCTGCGTGGGTGCCTACACCACCGCCATCCTGTGCGAGCACG
GTGTGCCGATGGTCGTGACATTCCCGCTCGCGGCCCTGCTCGCCATGCTGGCCGCCTGGCCGCTGGGGCTCGTCAGCATC
CGCCTCAGGGAAGACTATTTTGCCATCGTCTCGCTCGGCTTCTCGGAAGTGGTGCGTCTCGTCGCGACCAGCGAGCGCTG
GCTGACCAATGGCGTGCAGGGCATCGCCGGCATCCCCAAGATGTTCGGCATGCTCACCGGCACGCCCCAGGCTCTGGCGG
TGCTCGGGCTGCTGGTGGTGCTGAACCTCATCGCCATCGCCGCCATGTGGCGCATCGTGCGCTCACCCTTCGGGCGCATG
ATCGAGGCCATCCGCGACAATGAGGAGGCGGTGAAGGCGCTCGGCAAGGACCCGGCCGGCTTCAAGATCCAGGTTCTGGT
GCTGGGCGCCGGCCTCGCGGGCATCGCGGGCGCGGTCTATGCCCATTACATCGGCTTCATCGCGCCCGAGCAGTTCGTCC
CGCTCATGACCTTCCAGATCTGGATGGCCATCATCATGGGCGGCGTGGGGCGCATCTCCGGCGCGCTGGTTGGCGCGGTG
ATCCTCATGTTCTTCCTGGAGGGCTCGCGCTTCCTGCGCGACCTTCTGCCTTTCATCTCGGAAGTCTCCATGGCGAGCGT
CCGGCTCGGCGTGGTGGGTCTGGCACTCATCCTCTTCACCATGTACCGCCCGCAGGGCCTGATGGGGGATTTCACCCGCA
AATGA

Upstream 100 bases:

>100_bases
TGGGCTTCACCTACAAGCTGGCGCTTGCCTTCGTCATCCTGCTGGTGGTGCTGCTGGTGCGGCCCAAGGGCCTGTTCGGC
CGCGTGGAGGGGGTGCGCTG

Downstream 100 bases:

>100_bases
CCCTCTCGATCCAAGGACTGACCAAGGCCTATGGCGGCCTGCGCGTGGTGGATGAGGTGCGCTTCGAGGTGCCTTCCGGC
GCGCTCGTGGGCGTGATCGG

Product: ABC transport permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDAYLIAIAIIGALYVLLALGLNLQYGLTGIVNFGHVGFFCVGAYTTAILCEHGVPMVVTFPLAALLAMLAAWPLGLVSI
RLREDYFAIVSLGFSEVVRLVATSERWLTNGVQGIAGIPKMFGMLTGTPQALAVLGLLVVLNLIAIAAMWRIVRSPFGRM
IEAIRDNEEAVKALGKDPAGFKIQVLVLGAGLAGIAGAVYAHYIGFIAPEQFVPLMTFQIWMAIIMGGVGRISGALVGAV
ILMFFLEGSRFLRDLLPFISEVSMASVRLGVVGLALILFTMYRPQGLMGDFTRK

Sequences:

>Translated_294_residues
MDAYLIAIAIIGALYVLLALGLNLQYGLTGIVNFGHVGFFCVGAYTTAILCEHGVPMVVTFPLAALLAMLAAWPLGLVSI
RLREDYFAIVSLGFSEVVRLVATSERWLTNGVQGIAGIPKMFGMLTGTPQALAVLGLLVVLNLIAIAAMWRIVRSPFGRM
IEAIRDNEEAVKALGKDPAGFKIQVLVLGAGLAGIAGAVYAHYIGFIAPEQFVPLMTFQIWMAIIMGGVGRISGALVGAV
ILMFFLEGSRFLRDLLPFISEVSMASVRLGVVGLALILFTMYRPQGLMGDFTRK
>Mature_294_residues
MDAYLIAIAIIGALYVLLALGLNLQYGLTGIVNFGHVGFFCVGAYTTAILCEHGVPMVVTFPLAALLAMLAAWPLGLVSI
RLREDYFAIVSLGFSEVVRLVATSERWLTNGVQGIAGIPKMFGMLTGTPQALAVLGLLVVLNLIAIAAMWRIVRSPFGRM
IEAIRDNEEAVKALGKDPAGFKIQVLVLGAGLAGIAGAVYAHYIGFIAPEQFVPLMTFQIWMAIIMGGVGRISGALVGAV
ILMFFLEGSRFLRDLLPFISEVSMASVRLGVVGLALILFTMYRPQGLMGDFTRK

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=307, Percent_Identity=31.2703583061889, Blast_Score=134, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 31497; Mature: 31497

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]