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The map label for this gene is mcp4 [H]

Identifier: 158424605

GI number: 158424605

Start: 3407320

End: 3409017

Strand: Reverse

Name: mcp4 [H]

Synonym: AZC_2981

Alternate gene names: 158424605

Gene position: 3409017-3407320 (Counterclockwise)

Preceding gene: 158424607

Following gene: 158424604

Centisome position: 63.49

GC content: 66.61

Gene sequence:

>1698_bases
TTGCTCTACAATAATCTGAAGATGATCTGGAAGATCGTCGCCCTTCTTGTGCTGCTTGGCGCTGTCAGCATCGGCGGTGC
CCTCTATGGCGCCAGCCAGTCCACGGCGATCAACGACTTGTTGTCCGGCATCATCGAAGGGCCGGCCGCTGCCGCGACGC
GGATGGCCCGCGCCAATCGATTCATGGTGAGAACGGAGCTTGCCATCTATCAGTTGATCAACGCGCCCGACGATGCGTCG
GTCGCCGCCGCCGACAAGGCGATGAACGAAGTCGTCGAGACCGCCCGCGGCATCTTTTCCGATGCGGCCAAGCTCGCTCC
GGCCTTCTCGTCGCGCATCGAGAGCATCGGCAGCAGTTTTTCGCGGACCATGGAAACGGCCTGTGCCTCTACGATCAAGC
TGTCGCTGGTGGCCCGCACGCCGGCGGAGAATGCACGTGCCGCGGCATTGATGCGGTCCGAATGCGAGCCGGCGATCGAG
AAGATCAGCCAGGACTCCGTCGCGCTCACCGCCGAGATGCAGACCTACATGGCCGATGAAAACAAGCGGGCCGATGACGT
GACGGCCAGCGCCAATGCGACCTCCATCTCGGTGATCGTCGCCGCCACCGTGCTGGTCATCGGCCTCGCGCTCTTCCTCG
TGCGCCGGAGCATCGTGCGCCCGCTCGAGGCGATGATGGGCGTGATGGAGGCCATGGGCCACGGCGATCTCAGCCGCAAG
CCGGACGAGACCGGACGGGCGGACGAGATCGGCGCCATGTCCCGCACGCTCACCGTCCTTGGCGAGCAGTTGCAGGCTGC
GGAAGCCGCCCGTCAGCAGCAGGCGGAGCGGGAAGCCGCCGAGCGGCTTCAGATCCAGAAGCGGCAGAAGCTCGCCGAGG
CATTCGTCGCCGAGATCCAGCAGATCGCTGCGACCTTTGCCGATTCGTCGGCGCAGGTGGCCGATTCCGCCCGCAACCTG
TCGGCAACGGCGGAGCAGACCTCCCGGCAGGCCCAGGCTGTCGCGAGCGCGGCCGAGGAGGCGGCGACCAATGTCCAGAC
GGTGGCGGCCTCTTCCGAGGAACTGGCGGCCTCCGTGCGCGAGATCACCGGGCAGGTGAGCCATTCGGCCTCGGTCGCGG
AAGTAGCCTTCCGCGAGGCGGAAACCTCCAACGAGCGCATCGTGGAACTCGCCCGCTCGGCACAGGCCATCGGTGACGTG
ATCGTCCTGATCAAGGGCATTGCGGACCAGACCAATCTCCTTGCGCTCAACGCGACCATCGAATCCGCCCGCGCCGGCGA
GGCCGGCAAGGGCTTTGCCGTGGTGGCGTCCGAGGTGAAGGAACTGGCGGCCCAGACCGGCAAGGCGACGGACGAGATCG
CCAGCAAGATCGCCGAAATCCAGCAGGCGACGCAGGGCACCGTCAGCTCCATGGGCGAGATCATCCGCGTGGTGGGCAAC
ATCAAGCAGATCTCCTCCTCCATCGCCGGCGCGGTGGAGCAGCAGGGCGCGGCCACCGGTGAAATCGCCCAGAACTGCCA
GCAGGCCGCCACCGGCACCCAGCAGGTGACGGAGAATATCGGCGGCGTGGGGCAGGCGGCCGAACTCACCGGCTCGGCCT
CCAGCCAGTTGCTGACCCTGTCGCAGGGCCTGTCTACCCAAGCAGTCGACCTGCGGCGGACGGTGGAACGGTTCGTGTCG
GACCTCCACGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCCGCCCACACACGGGTTCCGCTTCGGCAAGTTTGGCGCAAGATGAGGGTAATAGGGGAGGGAGGTCTCTCTGAGGTTG
TATGAAGTCCGGAGGCTTTC

Downstream 100 bases:

>100_bases
GGCGCCGACGGGGCGGGTGCTGGCTCCAGCGCCCGCCTTCCCGCGCAAGCCCAAGGCAAGGTCGGGGCGCGAGTGTGCCC
CATGCGCCCGCGGGCGATCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MLYNNLKMIWKIVALLVLLGAVSIGGALYGASQSTAINDLLSGIIEGPAAAATRMARANRFMVRTELAIYQLINAPDDAS
VAAADKAMNEVVETARGIFSDAAKLAPAFSSRIESIGSSFSRTMETACASTIKLSLVARTPAENARAAALMRSECEPAIE
KISQDSVALTAEMQTYMADENKRADDVTASANATSISVIVAATVLVIGLALFLVRRSIVRPLEAMMGVMEAMGHGDLSRK
PDETGRADEIGAMSRTLTVLGEQLQAAEAARQQQAEREAAERLQIQKRQKLAEAFVAEIQQIAATFADSSAQVADSARNL
SATAEQTSRQAQAVASAAEEAATNVQTVAASSEELAASVREITGQVSHSASVAEVAFREAETSNERIVELARSAQAIGDV
IVLIKGIADQTNLLALNATIESARAGEAGKGFAVVASEVKELAAQTGKATDEIASKIAEIQQATQGTVSSMGEIIRVVGN
IKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQQVTENIGGVGQAAELTGSASSQLLTLSQGLSTQAVDLRRTVERFVS
DLHAA

Sequences:

>Translated_565_residues
MLYNNLKMIWKIVALLVLLGAVSIGGALYGASQSTAINDLLSGIIEGPAAAATRMARANRFMVRTELAIYQLINAPDDAS
VAAADKAMNEVVETARGIFSDAAKLAPAFSSRIESIGSSFSRTMETACASTIKLSLVARTPAENARAAALMRSECEPAIE
KISQDSVALTAEMQTYMADENKRADDVTASANATSISVIVAATVLVIGLALFLVRRSIVRPLEAMMGVMEAMGHGDLSRK
PDETGRADEIGAMSRTLTVLGEQLQAAEAARQQQAEREAAERLQIQKRQKLAEAFVAEIQQIAATFADSSAQVADSARNL
SATAEQTSRQAQAVASAAEEAATNVQTVAASSEELAASVREITGQVSHSASVAEVAFREAETSNERIVELARSAQAIGDV
IVLIKGIADQTNLLALNATIESARAGEAGKGFAVVASEVKELAAQTGKATDEIASKIAEIQQATQGTVSSMGEIIRVVGN
IKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQQVTENIGGVGQAAELTGSASSQLLTLSQGLSTQAVDLRRTVERFVS
DLHAA
>Mature_565_residues
MLYNNLKMIWKIVALLVLLGAVSIGGALYGASQSTAINDLLSGIIEGPAAAATRMARANRFMVRTELAIYQLINAPDDAS
VAAADKAMNEVVETARGIFSDAAKLAPAFSSRIESIGSSFSRTMETACASTIKLSLVARTPAENARAAALMRSECEPAIE
KISQDSVALTAEMQTYMADENKRADDVTASANATSISVIVAATVLVIGLALFLVRRSIVRPLEAMMGVMEAMGHGDLSRK
PDETGRADEIGAMSRTLTVLGEQLQAAEAARQQQAEREAAERLQIQKRQKLAEAFVAEIQQIAATFADSSAQVADSARNL
SATAEQTSRQAQAVASAAEEAATNVQTVAASSEELAASVREITGQVSHSASVAEVAFREAETSNERIVELARSAQAIGDV
IVLIKGIADQTNLLALNATIESARAGEAGKGFAVVASEVKELAAQTGKATDEIASKIAEIQQATQGTVSSMGEIIRVVGN
IKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQQVTENIGGVGQAAELTGSASSQLLTLSQGLSTQAVDLRRTVERFVS
DLHAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=334, Percent_Identity=31.437125748503, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI2367378, Length=361, Percent_Identity=29.6398891966759, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787690, Length=328, Percent_Identity=29.5731707317073, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788195, Length=196, Percent_Identity=33.6734693877551, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=202, Percent_Identity=35.6435643564356, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58880; Mature: 58880

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYNNLKMIWKIVALLVLLGAVSIGGALYGASQSTAINDLLSGIIEGPAAAATRMARANR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
FMVRTELAIYQLINAPDDASVAAADKAMNEVVETARGIFSDAAKLAPAFSSRIESIGSSF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTMETACASTIKLSLVARTPAENARAAALMRSECEPAIEKISQDSVALTAEMQTYMADE
HHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
NKRADDVTASANATSISVIVAATVLVIGLALFLVRRSIVRPLEAMMGVMEAMGHGDLSRK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDETGRADEIGAMSRTLTVLGEQLQAAEAARQQQAEREAAERLQIQKRQKLAEAFVAEIQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIAATFADSSAQVADSARNLSATAEQTSRQAQAVASAAEEAATNVQTVAASSEELAASVR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EITGQVSHSASVAEVAFREAETSNERIVELARSAQAIGDVIVLIKGIADQTNLLALNATI
HHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHH
ESARAGEAGKGFAVVASEVKELAAQTGKATDEIASKIAEIQQATQGTVSSMGEIIRVVGN
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQQVTENIGGVGQAAELTGSASSQLLTL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHCCCCHHHHHHH
SQGLSTQAVDLRRTVERFVSDLHAA
HCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYNNLKMIWKIVALLVLLGAVSIGGALYGASQSTAINDLLSGIIEGPAAAATRMARANR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
FMVRTELAIYQLINAPDDASVAAADKAMNEVVETARGIFSDAAKLAPAFSSRIESIGSSF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTMETACASTIKLSLVARTPAENARAAALMRSECEPAIEKISQDSVALTAEMQTYMADE
HHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
NKRADDVTASANATSISVIVAATVLVIGLALFLVRRSIVRPLEAMMGVMEAMGHGDLSRK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDETGRADEIGAMSRTLTVLGEQLQAAEAARQQQAEREAAERLQIQKRQKLAEAFVAEIQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIAATFADSSAQVADSARNLSATAEQTSRQAQAVASAAEEAATNVQTVAASSEELAASVR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EITGQVSHSASVAEVAFREAETSNERIVELARSAQAIGDVIVLIKGIADQTNLLALNATI
HHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHH
ESARAGEAGKGFAVVASEVKELAAQTGKATDEIASKIAEIQQATQGTVSSMGEIIRVVGN
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQQVTENIGGVGQAAELTGSASSQLLTL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHCCCCHHHHHHH
SQGLSTQAVDLRRTVERFVSDLHAA
HCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]