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The map label for this gene is fadN [H]

Identifier: 158424597

GI number: 158424597

Start: 3396766

End: 3399090

Strand: Direct

Name: fadN [H]

Synonym: AZC_2973

Alternate gene names: 158424597

Gene position: 3396766-3399090 (Clockwise)

Preceding gene: 158424596

Following gene: 158424598

Centisome position: 63.26

GC content: 67.48

Gene sequence:

>2325_bases
ATGAGCGAGATCCGCAAGGCCGCCGTCATCGGCGCCGGCGTCATGGGCGCCGGCATTGCCGCCCACATCGCCAATGCCGG
GGTGGAGGTGCTCCTCCTCGACATCGTGCCCGAGGGCGCAACCAACCGCAGCGCCATCGCCGAAAAGGCGGTGGAGCGGC
TCCTGAAGGCGGAGCCCGCCGCCTTCATGTCCAAGCGCAGCGCCAAGCTGGTGAAGGCCGGCAATATCGAGGACGACCTC
CCCGCCCTCGCCGAGTGCGACTGGATCGTGGAAGCGGTGGTGGAGCGGCTCGATGTGAAGCAGGCGCTCTACAGGAAGAT
CGACGCCGTGCGGAAGCCGGGCACGGCGGTCTCCTCCAACACCTCCACCATTCCGCTCGCGGCGCTGACGGAAGGGCTGT
CGGACGGCTTCCGCCGTGACTTCCTCATCACCCATTTCTTCAATCCGCCGCGCTACATGCGCCTGCTGGAGATCGTCTCG
GGACCGGAGACGGATCCCGCGACCGTCGCCCGCGTCAGCGCCTTCGCCGACGTGAAGCTCGGCAAGACGGTGGTGACCTG
CAAGGATACGCCCGGCTTCATCGCCAACCGCCTCGGCACCTACTGGATGCAGCTTGCGGTGGGCGAGGCCTTCGCCCTCG
GCCTCACGGTCGAGGAAGCCGACAGCGTCATGGGCCGGCCCTTCGGCATTCCCAAGACCGGCGTATTCGGCCTGCTCGAC
CTCGTCGGCCTCGACCTCATGCCGCACGTGCAGGGCAGCCTTGAGCGCGCGCTGCCGAAGGACGATCCGTTCCAGAAGAC
GGTGCGTGACATCCCCCTCATCCGCACCATGATCGAGACCGGCCTCATCGGCCGGAAGGGCAAGGGCGGCTTCTACCGGC
TGAACCGCGAGGGCGGCGGCAAGGTGAAGGAAGCCATTGATCTTGCGAGCGGCAGCTACCGCCGAGAGGAGAAGGCCCGC
CTGCCGGAAGTGGAAGCGGCCGCCAAGAATGTCGGCGCCCTGCTCGGCGCCACGACGCCCGCCGGCCGCTATGCGGTCTC
CGTCATGGCCCGCACCCTCGCCTATGCCGCCTGGCTTGTGCCGGCGGCGGCGGACGACGTGGTGGCCATCGATGACGCCA
TGCGCCTCGGCTACAACTGGAAATGGGGGCCGTTCGAGCTGATCGACCGCATCGGCGCGCCCGCGCTCATCGCCGCGCTG
GACGGCATGGGAGAGCCGGTGCCGGAATTCCTGACGCTCGCCCGCGACAAGACCTTCTACCGGGTCGAGAACGGCAAGCG
GCAGTATCTCGGCCGCGACGGCATCTATCGCGACATCGTGCGTCCCGAAGGCGTGCTGCTGCTCTCCGACATCAAGCTCA
CCGCCCAGCCGGTACTTAAGAACAGTTCGGCGGCCGTGTGGGATCTCGGCGACGGCGTGCTGTGCTTCGAGTTCACCTCC
AAGTCCAATTCACTGGACGAGGGCATCATCACGCTCCTGGGCAAGGCGTCCAAGCTCGTGAAGGACAAGCACAAGGCGCT
CGTCATCTATAACGAGGGCTCCAACTTCTCCGTGGGCGCCAATCTCGGCCTCGCGCTGTTCGCCTGCAACATCGCCGCCT
TCGGCGAGGTGGAGAAGCTGGTGGCGGCAGGCCAGCAGGCCTATCAGGCGCTGAAATACGCCACCTTCCCCGTGGTGTCG
GCCCCCGCCGGCATGGCGCTCGGCGGCGGATGCGAGATCCTCTTGCATTCGGATGCCGTGCAGGCCCATGCGGAGAGCTA
TATCGGCCTCGTGGAATGCGGCGTCGGCGTGCTGCCCGGCTGGGGCGGCTGCAAGGAGATGCTGACCCGCTGGCAGACCG
ACCCGGCCCTGCCCAAGGGCCCCATGCCCGCGCCCTCCAAGGTGTTCGAGATGGTGAGCACCGCCACCGTGTCGAAATCC
GCCGCCGAGGCCAAGGAATACAAATTCCTGCGCGAGAGCGACGGCATCACCATGAACCGCGACCGCCTGCTGGCGGACGC
CAAGGCCAAGGCGCTTGCGCTGGCGGAAAACTATGTGCCGCCGAAGCCCGTGGACCTGACGCTGCCAGGCCCTTCCGGCC
GCGTGGCGCTGGAGATGGCGGCTGAGAGCTTCCACAAGCGCGGCATCGCCACCAAGCACGATCTGGTGGTGGCCTCCGCG
CTCGCGGAAGTGCTCACCGGCGGCCCGGCGGATCACATCCAGCCGGTCACCGAGGCGCAGGTTCTGGAACTGGAGCGGGC
CGGCTTCATGAAGCTGATCCGCACCAATGCGACGCTGGCGCGGATCGAGTCCGTGCTGGAAACGGGACGCCCGCTGCGCA
ACTGA

Upstream 100 bases:

>100_bases
TGAAGCGCGAGGGCGGTCGCTATGCGGTCGCCACCCAGTGCATTGGCGGCGGCCAGGGCATCGCCACCGTTCTCGAGCGC
GTGTGAGCGGAGGCGCCACC

Downstream 100 bases:

>100_bases
CCGCAGGGCGCGGAAACGGCCGCTGCGACCGGGGGCGGACAGCAGCGGCCAGGGGCATGGCCGGCGCGGCATGCTGCGGC
CGGCCATGCCCTATCCGCCG

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MSEIRKAAVIGAGVMGAGIAAHIANAGVEVLLLDIVPEGATNRSAIAEKAVERLLKAEPAAFMSKRSAKLVKAGNIEDDL
PALAECDWIVEAVVERLDVKQALYRKIDAVRKPGTAVSSNTSTIPLAALTEGLSDGFRRDFLITHFFNPPRYMRLLEIVS
GPETDPATVARVSAFADVKLGKTVVTCKDTPGFIANRLGTYWMQLAVGEAFALGLTVEEADSVMGRPFGIPKTGVFGLLD
LVGLDLMPHVQGSLERALPKDDPFQKTVRDIPLIRTMIETGLIGRKGKGGFYRLNREGGGKVKEAIDLASGSYRREEKAR
LPEVEAAAKNVGALLGATTPAGRYAVSVMARTLAYAAWLVPAAADDVVAIDDAMRLGYNWKWGPFELIDRIGAPALIAAL
DGMGEPVPEFLTLARDKTFYRVENGKRQYLGRDGIYRDIVRPEGVLLLSDIKLTAQPVLKNSSAAVWDLGDGVLCFEFTS
KSNSLDEGIITLLGKASKLVKDKHKALVIYNEGSNFSVGANLGLALFACNIAAFGEVEKLVAAGQQAYQALKYATFPVVS
APAGMALGGGCEILLHSDAVQAHAESYIGLVECGVGVLPGWGGCKEMLTRWQTDPALPKGPMPAPSKVFEMVSTATVSKS
AAEAKEYKFLRESDGITMNRDRLLADAKAKALALAENYVPPKPVDLTLPGPSGRVALEMAAESFHKRGIATKHDLVVASA
LAEVLTGGPADHIQPVTEAQVLELERAGFMKLIRTNATLARIESVLETGRPLRN

Sequences:

>Translated_774_residues
MSEIRKAAVIGAGVMGAGIAAHIANAGVEVLLLDIVPEGATNRSAIAEKAVERLLKAEPAAFMSKRSAKLVKAGNIEDDL
PALAECDWIVEAVVERLDVKQALYRKIDAVRKPGTAVSSNTSTIPLAALTEGLSDGFRRDFLITHFFNPPRYMRLLEIVS
GPETDPATVARVSAFADVKLGKTVVTCKDTPGFIANRLGTYWMQLAVGEAFALGLTVEEADSVMGRPFGIPKTGVFGLLD
LVGLDLMPHVQGSLERALPKDDPFQKTVRDIPLIRTMIETGLIGRKGKGGFYRLNREGGGKVKEAIDLASGSYRREEKAR
LPEVEAAAKNVGALLGATTPAGRYAVSVMARTLAYAAWLVPAAADDVVAIDDAMRLGYNWKWGPFELIDRIGAPALIAAL
DGMGEPVPEFLTLARDKTFYRVENGKRQYLGRDGIYRDIVRPEGVLLLSDIKLTAQPVLKNSSAAVWDLGDGVLCFEFTS
KSNSLDEGIITLLGKASKLVKDKHKALVIYNEGSNFSVGANLGLALFACNIAAFGEVEKLVAAGQQAYQALKYATFPVVS
APAGMALGGGCEILLHSDAVQAHAESYIGLVECGVGVLPGWGGCKEMLTRWQTDPALPKGPMPAPSKVFEMVSTATVSKS
AAEAKEYKFLRESDGITMNRDRLLADAKAKALALAENYVPPKPVDLTLPGPSGRVALEMAAESFHKRGIATKHDLVVASA
LAEVLTGGPADHIQPVTEAQVLELERAGFMKLIRTNATLARIESVLETGRPLRN
>Mature_773_residues
SEIRKAAVIGAGVMGAGIAAHIANAGVEVLLLDIVPEGATNRSAIAEKAVERLLKAEPAAFMSKRSAKLVKAGNIEDDLP
ALAECDWIVEAVVERLDVKQALYRKIDAVRKPGTAVSSNTSTIPLAALTEGLSDGFRRDFLITHFFNPPRYMRLLEIVSG
PETDPATVARVSAFADVKLGKTVVTCKDTPGFIANRLGTYWMQLAVGEAFALGLTVEEADSVMGRPFGIPKTGVFGLLDL
VGLDLMPHVQGSLERALPKDDPFQKTVRDIPLIRTMIETGLIGRKGKGGFYRLNREGGGKVKEAIDLASGSYRREEKARL
PEVEAAAKNVGALLGATTPAGRYAVSVMARTLAYAAWLVPAAADDVVAIDDAMRLGYNWKWGPFELIDRIGAPALIAALD
GMGEPVPEFLTLARDKTFYRVENGKRQYLGRDGIYRDIVRPEGVLLLSDIKLTAQPVLKNSSAAVWDLGDGVLCFEFTSK
SNSLDEGIITLLGKASKLVKDKHKALVIYNEGSNFSVGANLGLALFACNIAAFGEVEKLVAAGQQAYQALKYATFPVVSA
PAGMALGGGCEILLHSDAVQAHAESYIGLVECGVGVLPGWGGCKEMLTRWQTDPALPKGPMPAPSKVFEMVSTATVSKSA
AEAKEYKFLRESDGITMNRDRLLADAKAKALALAENYVPPKPVDLTLPGPSGRVALEMAAESFHKRGIATKHDLVVASAL
AEVLTGGPADHIQPVTEAQVLELERAGFMKLIRTNATLARIESVLETGRPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=303, Percent_Identity=31.3531353135314, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI296179427, Length=320, Percent_Identity=30, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI261878539, Length=306, Percent_Identity=29.0849673202614, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI68989263, Length=306, Percent_Identity=29.0849673202614, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI20127408, Length=301, Percent_Identity=27.5747508305648, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI115430219, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790281, Length=232, Percent_Identity=34.4827586206897, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1787661, Length=304, Percent_Identity=32.8947368421053, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788682, Length=292, Percent_Identity=29.4520547945205, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17549919, Length=306, Percent_Identity=33.3333333333333, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17553560, Length=307, Percent_Identity=31.2703583061889, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17558304, Length=407, Percent_Identity=29.2383292383292, Blast_Score=116, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17508953, Length=411, Percent_Identity=28.4671532846715, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17508951, Length=411, Percent_Identity=28.4671532846715, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985923, Length=296, Percent_Identity=29.3918918918919, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=306, Percent_Identity=32.3529411764706, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17563036, Length=293, Percent_Identity=31.0580204778157, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985930, Length=297, Percent_Identity=25.9259259259259, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203623, Length=163, Percent_Identity=31.9018404907975, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533614, Length=163, Percent_Identity=31.9018404907975, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583077, Length=439, Percent_Identity=26.1958997722096, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583079, Length=439, Percent_Identity=26.1958997722096, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19921000, Length=439, Percent_Identity=26.1958997722096, Blast_Score=106, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45549573, Length=248, Percent_Identity=29.8387096774194, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129993, Length=248, Percent_Identity=29.4354838709677, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 82736; Mature: 82604

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIRKAAVIGAGVMGAGIAAHIANAGVEVLLLDIVPEGATNRSAIAEKAVERLLKAEPA
CCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCH
AFMSKRSAKLVKAGNIEDDLPALAECDWIVEAVVERLDVKQALYRKIDAVRKPGTAVSSN
HHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TSTIPLAALTEGLSDGFRRDFLITHFFNPPRYMRLLEIVSGPETDPATVARVSAFADVKL
CCCCCHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
GKTVVTCKDTPGFIANRLGTYWMQLAVGEAFALGLTVEEADSVMGRPFGIPKTGVFGLLD
CCEEEEECCCCCHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHCCCCCCCCCHHHHHHHH
LVGLDLMPHVQGSLERALPKDDPFQKTVRDIPLIRTMIETGLIGRKGKGGFYRLNREGGG
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCC
KVKEAIDLASGSYRREEKARLPEVEAAAKNVGALLGATTPAGRYAVSVMARTLAYAAWLV
HHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
PAAADDVVAIDDAMRLGYNWKWGPFELIDRIGAPALIAALDGMGEPVPEFLTLARDKTFY
CCCCCCEEEECHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCEE
RVENGKRQYLGRDGIYRDIVRPEGVLLLSDIKLTAQPVLKNSSAAVWDLGDGVLCFEFTS
EECCCCHHHCCCCCCHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEECCCCEEEEEECC
KSNSLDEGIITLLGKASKLVKDKHKALVIYNEGSNFSVGANLGLALFACNIAAFGEVEKL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHH
VAAGQQAYQALKYATFPVVSAPAGMALGGGCEILLHSDAVQAHAESYIGLVECGVGVLPG
HHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCC
WGGCKEMLTRWQTDPALPKGPMPAPSKVFEMVSTATVSKSAAEAKEYKFLRESDGITMNR
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECH
DRLLADAKAKALALAENYVPPKPVDLTLPGPSGRVALEMAAESFHKRGIATKHDLVVASA
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHH
LAEVLTGGPADHIQPVTEAQVLELERAGFMKLIRTNATLARIESVLETGRPLRN
HHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEIRKAAVIGAGVMGAGIAAHIANAGVEVLLLDIVPEGATNRSAIAEKAVERLLKAEPA
CHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCH
AFMSKRSAKLVKAGNIEDDLPALAECDWIVEAVVERLDVKQALYRKIDAVRKPGTAVSSN
HHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TSTIPLAALTEGLSDGFRRDFLITHFFNPPRYMRLLEIVSGPETDPATVARVSAFADVKL
CCCCCHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
GKTVVTCKDTPGFIANRLGTYWMQLAVGEAFALGLTVEEADSVMGRPFGIPKTGVFGLLD
CCEEEEECCCCCHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHCCCCCCCCCHHHHHHHH
LVGLDLMPHVQGSLERALPKDDPFQKTVRDIPLIRTMIETGLIGRKGKGGFYRLNREGGG
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCC
KVKEAIDLASGSYRREEKARLPEVEAAAKNVGALLGATTPAGRYAVSVMARTLAYAAWLV
HHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
PAAADDVVAIDDAMRLGYNWKWGPFELIDRIGAPALIAALDGMGEPVPEFLTLARDKTFY
CCCCCCEEEECHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCEE
RVENGKRQYLGRDGIYRDIVRPEGVLLLSDIKLTAQPVLKNSSAAVWDLGDGVLCFEFTS
EECCCCHHHCCCCCCHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEECCCCEEEEEECC
KSNSLDEGIITLLGKASKLVKDKHKALVIYNEGSNFSVGANLGLALFACNIAAFGEVEKL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHH
VAAGQQAYQALKYATFPVVSAPAGMALGGGCEILLHSDAVQAHAESYIGLVECGVGVLPG
HHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCC
WGGCKEMLTRWQTDPALPKGPMPAPSKVFEMVSTATVSKSAAEAKEYKFLRESDGITMNR
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECH
DRLLADAKAKALALAENYVPPKPVDLTLPGPSGRVALEMAAESFHKRGIATKHDLVVASA
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHH
LAEVLTGGPADHIQPVTEAQVLELERAGFMKLIRTNATLARIESVLETGRPLRN
HHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]