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The map label for this gene is stc [H]

Identifier: 158424548

GI number: 158424548

Start: 3342477

End: 3344420

Strand: Reverse

Name: stc [H]

Synonym: AZC_2924

Alternate gene names: 158424548

Gene position: 3344420-3342477 (Counterclockwise)

Preceding gene: 158424549

Following gene: 158424547

Centisome position: 62.28

GC content: 66.51

Gene sequence:

>1944_bases
ATGGACCAGCGGGACATCCGTTTGGCTTGGGAAACATTCCTGACCGATGGCTGCCCACCCGTGGGCGTTTCGGCTTCTTT
GCTGGCGTCTTGGCAGCGCTCCCGCACGCTTGGCGTCGGCGCAGGGCGCGCCGAGGCGCCATTGGCCGACGAACCGGAGA
TCTTCCGACGGCGCTCACAGAATGCCAGCCTTGTGGGCGCCGCCCGTCCGGCGTTGGATCGCTCCACCCGCTTCCTGGCA
GATGCCGCCTCCATGATGATCCTGGCCGATGCCAGCGGCTTCATTGTCGAGACCGCAGGTGATCCGCGGGTCATGGACAA
AGGCCGGCGCAATCATCTGGAAACCGGCGGGCGGTGGGATGAAGCCACCATCGGCACCAATGCCATCGGCACCGCCCTGG
CGGATGGGCGTTCGGTGGAGATCTGCGGGGCTGAGCATTTTTGCGAAGAGGTGCAGCGCTGGACCTGCGCCGCCACGCCA
GTGCGCCATCCCCTGGATGGCGAACTTCTCGGCGTGGTGGATATCTCGGGGCCGGCCGCCTCGTTCAATCCGCAAAGCCT
GTCGCTGGCGGTGGCCATCGGCCAGGAGATCGAGGCCTCGCTCGGCCGCGCCGCGAAGATGGAGCATGAGGTGCTGTTGC
GGCATTTCGTGTCGAAGCGTTCCATTTGGTTGAGCGAAGACATCCTGGTGGTGGATCGGCGCGGCATGCTGGTGCATGCC
GCGCACAAGGCCGGGTCGACCGGCAGTGGCCTGGCGGGCGACATCCGCCAGATGATCGGCGCCGCCTCCCAAGAGGCCTG
GGAGGCCAATTGCCGGCGCCGTTTCCCCAATGCCAGCCTGGAGGTGGTGAAGCGCGATGATGCGGTGGTCGGCTGCCTCA
TCGTTCTGCATACGACGCGGCGTCGGTCGGCATCACCGGCGGCGGTGCCCCGTCCGGCGGGAGAAGACGGGCTCGCGTTT
GAGCAGATCCTCGGCAATGACCCGGCACTGCACGCGGTGCGCGAGCGGGCGCGGCGGCTGGCGGCCAATCGTCTGCCGAT
CCTCATTGAGGGGGAGACCGGCGTCGGCAAGGAGTTGTTTGCCCGTGCCATCAAGGGCGCTAGCCCGGACCCAGACGGAC
CTTTCGTGCCGGTGAACTGTGGTGGCATGGCCCGGGAACTGATCGCCAGCGAACTGTTCGGCTATGCCAAAGGCGCGTTC
ACGGGTGCCGACGAACATGGCCGCGCCGGCAAGATCGAGAAAGCGGACGGCGGCATCCTGTGCCTGGACGAAATCGGCGA
AATGCCTCTCGACCTGCAATCCTATCTGCTGCGGGTGCTCGAGGATGGCGTGGTCTATCGCGTCGGCGAGCACGAGGGCC
GCCGGGTCAATATCCGCATCCTTGCGATGACTAATCGCGACCTGCTGGCGGAGGTGGAGGCGGGGCGGTTCCGCCGCGAC
CTCTATTATCGCATCGCCGCCGCGCGGCTGCGCATTCCCCCTCTGCGCGAGCGGGGGGCGGATATTGTCACTCTGGCGCA
AACATTCGCCGCAGCGGCCGCCAGCCGGCTGGGACGCAGTTCGCTTGTCTTCTCCGCTGCGGCACTGGACCGGATGCAGG
CCTATAGCTGGCCGGGCAACATCCGCGAACTGCGCAACGTGGTGGATACCCTAGTGGCATTGGCGGAAGGCGATCGGCTG
AACGAAAGCGACCTGCCGCCCGAGGTGCTCGCAGCACCGTCTCCCTCCCGAGCGCCTATCTCCCGCCCGCTCAACAACGG
CAGTGAGGGTTCTCCCCCACCGCCTGGCGCGGATCTCAAGGCGGCTGAACGCGCTGCCATTCTGGCCCAGGTGACTGCGT
GTGGTGGCAACCTCACCGAAGCTGCGCGGCGCCTCGGCATTGCCCGCTCGACCCTTTATGTGCGCCTCGCCGAGTATGGT
GATGGGCGTGTGCTCAAGAATTGA

Upstream 100 bases:

>100_bases
GCAGACGCGCGCGTCCCGGGTGACCGTCAGGCCATGTCCACGCTTCCGCTGGGTCGGACGCCAGGGCTTTCCCTTGCCGC
CCCCGTAGGAAGGACGCGAC

Downstream 100 bases:

>100_bases
CATCCGCTCCGGCCCGGTGTCCGTCCTCTGGACGTCCGGCTCAGGCACAGTTCGATATTCGGACATTCGCAGACGCAAAG
CGAGAACTGTGCAGGTGCGG

Product: sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MDQRDIRLAWETFLTDGCPPVGVSASLLASWQRSRTLGVGAGRAEAPLADEPEIFRRRSQNASLVGAARPALDRSTRFLA
DAASMMILADASGFIVETAGDPRVMDKGRRNHLETGGRWDEATIGTNAIGTALADGRSVEICGAEHFCEEVQRWTCAATP
VRHPLDGELLGVVDISGPAASFNPQSLSLAVAIGQEIEASLGRAAKMEHEVLLRHFVSKRSIWLSEDILVVDRRGMLVHA
AHKAGSTGSGLAGDIRQMIGAASQEAWEANCRRRFPNASLEVVKRDDAVVGCLIVLHTTRRRSASPAAVPRPAGEDGLAF
EQILGNDPALHAVRERARRLAANRLPILIEGETGVGKELFARAIKGASPDPDGPFVPVNCGGMARELIASELFGYAKGAF
TGADEHGRAGKIEKADGGILCLDEIGEMPLDLQSYLLRVLEDGVVYRVGEHEGRRVNIRILAMTNRDLLAEVEAGRFRRD
LYYRIAAARLRIPPLRERGADIVTLAQTFAAAAASRLGRSSLVFSAAALDRMQAYSWPGNIRELRNVVDTLVALAEGDRL
NESDLPPEVLAAPSPSRAPISRPLNNGSEGSPPPPGADLKAAERAAILAQVTACGGNLTEAARRLGIARSTLYVRLAEYG
DGRVLKN

Sequences:

>Translated_647_residues
MDQRDIRLAWETFLTDGCPPVGVSASLLASWQRSRTLGVGAGRAEAPLADEPEIFRRRSQNASLVGAARPALDRSTRFLA
DAASMMILADASGFIVETAGDPRVMDKGRRNHLETGGRWDEATIGTNAIGTALADGRSVEICGAEHFCEEVQRWTCAATP
VRHPLDGELLGVVDISGPAASFNPQSLSLAVAIGQEIEASLGRAAKMEHEVLLRHFVSKRSIWLSEDILVVDRRGMLVHA
AHKAGSTGSGLAGDIRQMIGAASQEAWEANCRRRFPNASLEVVKRDDAVVGCLIVLHTTRRRSASPAAVPRPAGEDGLAF
EQILGNDPALHAVRERARRLAANRLPILIEGETGVGKELFARAIKGASPDPDGPFVPVNCGGMARELIASELFGYAKGAF
TGADEHGRAGKIEKADGGILCLDEIGEMPLDLQSYLLRVLEDGVVYRVGEHEGRRVNIRILAMTNRDLLAEVEAGRFRRD
LYYRIAAARLRIPPLRERGADIVTLAQTFAAAAASRLGRSSLVFSAAALDRMQAYSWPGNIRELRNVVDTLVALAEGDRL
NESDLPPEVLAAPSPSRAPISRPLNNGSEGSPPPPGADLKAAERAAILAQVTACGGNLTEAARRLGIARSTLYVRLAEYG
DGRVLKN
>Mature_647_residues
MDQRDIRLAWETFLTDGCPPVGVSASLLASWQRSRTLGVGAGRAEAPLADEPEIFRRRSQNASLVGAARPALDRSTRFLA
DAASMMILADASGFIVETAGDPRVMDKGRRNHLETGGRWDEATIGTNAIGTALADGRSVEICGAEHFCEEVQRWTCAATP
VRHPLDGELLGVVDISGPAASFNPQSLSLAVAIGQEIEASLGRAAKMEHEVLLRHFVSKRSIWLSEDILVVDRRGMLVHA
AHKAGSTGSGLAGDIRQMIGAASQEAWEANCRRRFPNASLEVVKRDDAVVGCLIVLHTTRRRSASPAAVPRPAGEDGLAF
EQILGNDPALHAVRERARRLAANRLPILIEGETGVGKELFARAIKGASPDPDGPFVPVNCGGMARELIASELFGYAKGAF
TGADEHGRAGKIEKADGGILCLDEIGEMPLDLQSYLLRVLEDGVVYRVGEHEGRRVNIRILAMTNRDLLAEVEAGRFRRD
LYYRIAAARLRIPPLRERGADIVTLAQTFAAAAASRLGRSSLVFSAAALDRMQAYSWPGNIRELRNVVDTLVALAEGDRL
NESDLPPEVLAAPSPSRAPISRPLNNGSEGSPPPPGADLKAAERAAILAQVTACGGNLTEAARRLGIARSTLYVRLAEYG
DGRVLKN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=324, Percent_Identity=41.9753086419753, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1790437, Length=341, Percent_Identity=39.5894428152493, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1790299, Length=335, Percent_Identity=40.2985074626866, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1786524, Length=329, Percent_Identity=41.6413373860182, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI87082152, Length=266, Percent_Identity=46.6165413533835, Blast_Score=215, Evalue=7e-57,
Organism=Escherichia coli, GI87082117, Length=331, Percent_Identity=38.9728096676737, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1788905, Length=323, Percent_Identity=39.6284829721362, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789087, Length=328, Percent_Identity=38.4146341463415, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=33.9563862928349, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=353, Percent_Identity=33.1444759206799, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87081858, Length=649, Percent_Identity=25.7318952234206, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87081872, Length=261, Percent_Identity=40.2298850574713, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1789828, Length=257, Percent_Identity=35.7976653696498, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69375; Mature: 69375

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQRDIRLAWETFLTDGCPPVGVSASLLASWQRSRTLGVGAGRAEAPLADEPEIFRRRSQ
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHCCC
NASLVGAARPALDRSTRFLADAASMMILADASGFIVETAGDPRVMDKGRRNHLETGGRWD
CCCEEECCCCHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCHHHCCCCHHCCCCCCCCC
EATIGTNAIGTALADGRSVEICGAEHFCEEVQRWTCAATPVRHPLDGELLGVVDISGPAA
CCCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEECCCCC
SFNPQSLSLAVAIGQEIEASLGRAAKMEHEVLLRHFVSKRSIWLSEDILVVDRRGMLVHA
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEECCCCEEEE
AHKAGSTGSGLAGDIRQMIGAASQEAWEANCRRRFPNASLEVVKRDDAVVGCLIVLHTTR
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCHHEEEHHEEEEHH
RRSASPAAVPRPAGEDGLAFEQILGNDPALHAVRERARRLAANRLPILIEGETGVGKELF
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHH
ARAIKGASPDPDGPFVPVNCGGMARELIASELFGYAKGAFTGADEHGRAGKIEKADGGIL
HHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCEE
CLDEIGEMPLDLQSYLLRVLEDGVVYRVGEHEGRRVNIRILAMTNRDLLAEVEAGRFRRD
EHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHHHHH
LYYRIAAARLRIPPLRERGADIVTLAQTFAAAAASRLGRSSLVFSAAALDRMQAYSWPGN
HHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
IRELRNVVDTLVALAEGDRLNESDLPPEVLAAPSPSRAPISRPLNNGSEGSPPPPGADLK
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AAERAAILAQVTACGGNLTEAARRLGIARSTLYVRLAEYGDGRVLKN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEECCCCCEECC
>Mature Secondary Structure
MDQRDIRLAWETFLTDGCPPVGVSASLLASWQRSRTLGVGAGRAEAPLADEPEIFRRRSQ
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHCCC
NASLVGAARPALDRSTRFLADAASMMILADASGFIVETAGDPRVMDKGRRNHLETGGRWD
CCCEEECCCCHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCHHHCCCCHHCCCCCCCCC
EATIGTNAIGTALADGRSVEICGAEHFCEEVQRWTCAATPVRHPLDGELLGVVDISGPAA
CCCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEECCCCC
SFNPQSLSLAVAIGQEIEASLGRAAKMEHEVLLRHFVSKRSIWLSEDILVVDRRGMLVHA
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEECCCCEEEE
AHKAGSTGSGLAGDIRQMIGAASQEAWEANCRRRFPNASLEVVKRDDAVVGCLIVLHTTR
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCHHEEEHHEEEEHH
RRSASPAAVPRPAGEDGLAFEQILGNDPALHAVRERARRLAANRLPILIEGETGVGKELF
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHH
ARAIKGASPDPDGPFVPVNCGGMARELIASELFGYAKGAFTGADEHGRAGKIEKADGGIL
HHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCEE
CLDEIGEMPLDLQSYLLRVLEDGVVYRVGEHEGRRVNIRILAMTNRDLLAEVEAGRFRRD
EHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHHHHH
LYYRIAAARLRIPPLRERGADIVTLAQTFAAAAASRLGRSSLVFSAAALDRMQAYSWPGN
HHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
IRELRNVVDTLVALAEGDRLNESDLPPEVLAAPSPSRAPISRPLNNGSEGSPPPPGADLK
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AAERAAILAQVTACGGNLTEAARRLGIARSTLYVRLAEYGDGRVLKN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA