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The map label for this gene is iclR [H]

Identifier: 158424508

GI number: 158424508

Start: 3286344

End: 3287198

Strand: Direct

Name: iclR [H]

Synonym: AZC_2884

Alternate gene names: 158424508

Gene position: 3286344-3287198 (Clockwise)

Preceding gene: 158424507

Following gene: 158424509

Centisome position: 61.2

GC content: 69.01

Gene sequence:

>855_bases
GTGTGCATTGTGTACGATACAAAAAGAGACCGGGGGATCCGGCGAGACGGGGAAATGGCCGACGACAGGGACGCGACGCC
CGAGAAGAGCGACGGCGTGCGCGCTTTGCGCCGGGGCCTCGCGGTGCTGCGGCACATCAATGCCTGCGGCAGCACGTCGG
CGGCGGAGATCGCCCGCGCGCTCAGCATTCCCCGGCCCACGGTCTATCGGCTGCTGCAGACGCTGGAGGAAGAGGGCTAC
GTGGCCTTTTCCGCCTCCTCCACGCAGGTCCGCGTCACCCGCCTCGCCGCCAGCCTTGGCGACGGCTATGCCGCGCAGGC
GCGCATCTGCCAGGCGGCAGGCCCCGTGTTCGGCCATTATGCGCCCCGCCTCGTGTGGCCTCTCGATCTGACGGTCTATG
AGGATGCGGCCATGGTCATCCAGGAGACCACCCACACCCGCAGCCCCCTATCCATCGACCGCGGCATGATCGGCTTCCGC
CTGCCCATGCTCAGGACCTCCGCCGGGCGCGCCTATCTCGCCTATTGTCCGCCGGAAGACCGGCAGGCCATCCTCGGCCA
CCTGCGGCGCATGGATGACGGGGAGGACCGTCCCTTCCTCGATGACGCCTGGCTGGCGCGCTGCTTGTCGGAAACCCGGA
AGAACGGATTCGCGGTGCGCGATGGCGGCGAGTTCCGGCCGAAGACCAGCAGCATCGCTGTGCCGGTGATGGTGGGCCAG
CGGGTGGAGGCGGTGGTTTCCATGATCTGGATCCGTTCCGCCCTCTCACTCGCCGAAGCCATCCGCGCCCACGGAAGGAC
GCTCGCGGAGGTCGCCTCGGCCATCGCGCAGGCGGGCGCGCCACCGCCCGATTGA

Upstream 100 bases:

>100_bases
GTCGGCGTGCTGCGCAACCCGGTGGTCGCCGAGCGCTGAGCCCCCGGAAGGTTCCTTGAAGACGTGACACCTGCCGTGGC
TGGAACGCTGGCCACGGCAG

Downstream 100 bases:

>100_bases
GCTGACGCTGCCGCCCGGCCGGCATCCTCCGGCGTGCCGCGTTCCGGCCGCGAAGGTCAGAGCGCCACTCCAGGCACACG
CGCATGCGGTTTGATCACAC

Product: DNA-binding transcriptional activator MhpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MCIVYDTKRDRGIRRDGEMADDRDATPEKSDGVRALRRGLAVLRHINACGSTSAAEIARALSIPRPTVYRLLQTLEEEGY
VAFSASSTQVRVTRLAASLGDGYAAQARICQAAGPVFGHYAPRLVWPLDLTVYEDAAMVIQETTHTRSPLSIDRGMIGFR
LPMLRTSAGRAYLAYCPPEDRQAILGHLRRMDDGEDRPFLDDAWLARCLSETRKNGFAVRDGGEFRPKTSSIAVPVMVGQ
RVEAVVSMIWIRSALSLAEAIRAHGRTLAEVASAIAQAGAPPPD

Sequences:

>Translated_284_residues
MCIVYDTKRDRGIRRDGEMADDRDATPEKSDGVRALRRGLAVLRHINACGSTSAAEIARALSIPRPTVYRLLQTLEEEGY
VAFSASSTQVRVTRLAASLGDGYAAQARICQAAGPVFGHYAPRLVWPLDLTVYEDAAMVIQETTHTRSPLSIDRGMIGFR
LPMLRTSAGRAYLAYCPPEDRQAILGHLRRMDDGEDRPFLDDAWLARCLSETRKNGFAVRDGGEFRPKTSSIAVPVMVGQ
RVEAVVSMIWIRSALSLAEAIRAHGRTLAEVASAIAQAGAPPPD
>Mature_284_residues
MCIVYDTKRDRGIRRDGEMADDRDATPEKSDGVRALRRGLAVLRHINACGSTSAAEIARALSIPRPTVYRLLQTLEEEGY
VAFSASSTQVRVTRLAASLGDGYAAQARICQAAGPVFGHYAPRLVWPLDLTVYEDAAMVIQETTHTRSPLSIDRGMIGFR
LPMLRTSAGRAYLAYCPPEDRQAILGHLRRMDDGEDRPFLDDAWLARCLSETRKNGFAVRDGGEFRPKTSSIAVPVMVGQ
RVEAVVSMIWIRSALSLAEAIRAHGRTLAEVASAIAQAGAPPPD

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=255, Percent_Identity=36.4705882352941, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31036; Mature: 31036

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIVYDTKRDRGIRRDGEMADDRDATPEKSDGVRALRRGLAVLRHINACGSTSAAEIARA
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSIPRPTVYRLLQTLEEEGYVAFSASSTQVRVTRLAASLGDGYAAQARICQAAGPVFGHY
HCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHCC
APRLVWPLDLTVYEDAAMVIQETTHTRSPLSIDRGMIGFRLPMLRTSAGRAYLAYCPPED
CCCEEEEECEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHCCCCCCEEEEECCCCH
RQAILGHLRRMDDGEDRPFLDDAWLARCLSETRKNGFAVRDGGEFRPKTSSIAVPVMVGQ
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEHHHHHH
RVEAVVSMIWIRSALSLAEAIRAHGRTLAEVASAIAQAGAPPPD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MCIVYDTKRDRGIRRDGEMADDRDATPEKSDGVRALRRGLAVLRHINACGSTSAAEIARA
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSIPRPTVYRLLQTLEEEGYVAFSASSTQVRVTRLAASLGDGYAAQARICQAAGPVFGHY
HCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHCC
APRLVWPLDLTVYEDAAMVIQETTHTRSPLSIDRGMIGFRLPMLRTSAGRAYLAYCPPED
CCCEEEEECEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHCCCCCCEEEEECCCCH
RQAILGHLRRMDDGEDRPFLDDAWLARCLSETRKNGFAVRDGGEFRPKTSSIAVPVMVGQ
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEHHHHHH
RVEAVVSMIWIRSALSLAEAIRAHGRTLAEVASAIAQAGAPPPD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]