Click here to switch to the map view.

The map label for this gene is argS

Identifier: 158424430

GI number: 158424430

Start: 3190847

End: 3192607

Strand: Reverse

Name: argS

Synonym: AZC_2806

Alternate gene names: 158424430

Gene position: 3192607-3190847 (Counterclockwise)

Preceding gene: 158424431

Following gene: 158424429

Centisome position: 59.46

GC content: 66.33

Gene sequence:

>1761_bases
ATGAACGTCTACGCGATCTTCGCCGATCACGTGAGAGAAGCCGTCGCCGCTCTTGCCGGCGAACTGCCCGAGGCCGGCGC
GCTCGACCTCTCCCGGATCGTCGTCGAGCCCCCGCGTGACGCCGCCCATGGCGATCTCGCCACCAATGCGGCCATGGTCC
TCGCCAAGGACCTGAAGATGAAGCCGCGCGATCTCGCCGAGAAGATCGCCGCGCGGCTCGCGCAGGTGCCGAACGTGGCC
AAGGTGGACGTGGCCGGACCCGGCTTCATCAACCTCACCCTCGACGCCGGTTACTGGCCCGGCGTGCTCGCCGCGCTGCT
GCGCGCGGGCACCGACTTCGGCCGCTCGGACCTCGGGGGCGGGGAGGCGGTGAACGTGGAATACGTCTCCGCCAACCCCA
CCGGCCCCATGCATGTGGGCCATTGCCGGGGCGCGGTGTTCGGCGATGCGCTGGCGAGCCTCCTGGCTTTCGCCGGTTTC
AAGGTGACCCGCGAATATTACATCAACGACGCGGGCGCCCAGGTGGACGTGCTCGCTCGCTCCGCCTACCTGCGCTATCG
CGAGGCGGCCACCGGCGAGACGGTCGAGATCCCCGACGGGCTCTATCCGGGCGATTACCTCGTGCCCGTGGGCAAGACGC
TCGCCGAGGTGCACGGCTCGGAATATCTGGAATCGCCCGAGAGCGAGTGGCTGCCGATTTTCCGCACCTTCGCCATCGGC
GCGATGATGGAGATGATCCGCGACGATCTCCAGGCGCTCGGCATCTCCTTCGACGTCTTCTTCTCCGAGCGCTCGCTGAC
CGCCGCCGGCATCGACCGGGTGGGCCTCACCATCGAGCAACTGCGTCGCACCGGGGAGGTTTATGAGGGCCGTCTGCCGC
CGCCCAAGGGCGCGCCCATCGAGGACTGGGAGGATCGCGAGCAGAGCCTGTTCCGCTCCACCGCCCATGGTGACGATGTG
GACCGCCCGCTGGTGAAGTCCGACGGCAGCTACACCTATTTCGCCGGCGACATCGCCTATCACAAGGACAAGTTCGACCG
CGGCTTCCGCCGCATGATCGATGTCTGGGGCGCCGACCATGGCGGCTATGTGAAGCGCATGCAGGCCGCCGTGAAGGCGG
TCACCGCCGGTCAGGCGACCCTCGATGTGGAACTGTGTCAGCTCGTGCGCCTGCTGCGCAACGGCGAGCAGGTGCGCATG
TCGAAGCGCGCGGGCTCCTTCGTCACGCTCCGCGAGGTGGTGGACGAGGTGGGGCGCGATGCGGTCCGCTTCATGATGCT
GTTCCGCAAGAATGACGCGACGCTCGATTTCGATCTCGCGAAGGTGATCGAGCAGTCCCGCGAGAACCCCGTATTCTATG
TGCAGTATGCGCATGCGCGGGCGCAGTCGATCCTGCGCAACGCGAAGGAACAGCATGCCGATCTGCCGGAAAGCGGCGCC
ATTTATGCGCACGCGCCGCTGGACCGGTTGACGGACGAGGGCGAACTTGGTCTGGTGAAGCGGCTGGCGGGCTGGCCGCG
CCTTGTGGAGCAGGCGGCTCACGCCCGCGAACCGCACCGCGTGGCCTTCTATCTGCATGAGGTGGCGAGCGAGTTCCACG
GACAGTGGAACCGCGGAAAAGACTTGCCACATTTACGCTTCATTATCGAGAATGATCGAGAATTGACCATGGCCCGTCTG
GCTTTGGTCCACGGCGTGGCTGCGGTCCTCGCCTCTGGCCTTGGCTTGCTGGGTGTCGAGGCCGTCGACGAAATGAAGTG
A

Upstream 100 bases:

>100_bases
CATGACCGACCGTTACGCCCTCGACCAGCACGCCCGCTTTTTTGACACGACGCCGGAATTGCGTTAGGCGCCCGGCTGCT
TTCACCACACGGATGATGCC

Downstream 100 bases:

>100_bases
CCGTCGCGGGTCGGAGCCGCCAGAGCCGGCGGCCCGCCACCCTCGATGGCCGATGGGCATAATCGAGGCGACATGGGCGA
CGAAAGCAGGTTCCGCTACC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MNVYAIFADHVREAVAALAGELPEAGALDLSRIVVEPPRDAAHGDLATNAAMVLAKDLKMKPRDLAEKIAARLAQVPNVA
KVDVAGPGFINLTLDAGYWPGVLAALLRAGTDFGRSDLGGGEAVNVEYVSANPTGPMHVGHCRGAVFGDALASLLAFAGF
KVTREYYINDAGAQVDVLARSAYLRYREAATGETVEIPDGLYPGDYLVPVGKTLAEVHGSEYLESPESEWLPIFRTFAIG
AMMEMIRDDLQALGISFDVFFSERSLTAAGIDRVGLTIEQLRRTGEVYEGRLPPPKGAPIEDWEDREQSLFRSTAHGDDV
DRPLVKSDGSYTYFAGDIAYHKDKFDRGFRRMIDVWGADHGGYVKRMQAAVKAVTAGQATLDVELCQLVRLLRNGEQVRM
SKRAGSFVTLREVVDEVGRDAVRFMMLFRKNDATLDFDLAKVIEQSRENPVFYVQYAHARAQSILRNAKEQHADLPESGA
IYAHAPLDRLTDEGELGLVKRLAGWPRLVEQAAHAREPHRVAFYLHEVASEFHGQWNRGKDLPHLRFIIENDRELTMARL
ALVHGVAAVLASGLGLLGVEAVDEMK

Sequences:

>Translated_586_residues
MNVYAIFADHVREAVAALAGELPEAGALDLSRIVVEPPRDAAHGDLATNAAMVLAKDLKMKPRDLAEKIAARLAQVPNVA
KVDVAGPGFINLTLDAGYWPGVLAALLRAGTDFGRSDLGGGEAVNVEYVSANPTGPMHVGHCRGAVFGDALASLLAFAGF
KVTREYYINDAGAQVDVLARSAYLRYREAATGETVEIPDGLYPGDYLVPVGKTLAEVHGSEYLESPESEWLPIFRTFAIG
AMMEMIRDDLQALGISFDVFFSERSLTAAGIDRVGLTIEQLRRTGEVYEGRLPPPKGAPIEDWEDREQSLFRSTAHGDDV
DRPLVKSDGSYTYFAGDIAYHKDKFDRGFRRMIDVWGADHGGYVKRMQAAVKAVTAGQATLDVELCQLVRLLRNGEQVRM
SKRAGSFVTLREVVDEVGRDAVRFMMLFRKNDATLDFDLAKVIEQSRENPVFYVQYAHARAQSILRNAKEQHADLPESGA
IYAHAPLDRLTDEGELGLVKRLAGWPRLVEQAAHAREPHRVAFYLHEVASEFHGQWNRGKDLPHLRFIIENDRELTMARL
ALVHGVAAVLASGLGLLGVEAVDEMK
>Mature_586_residues
MNVYAIFADHVREAVAALAGELPEAGALDLSRIVVEPPRDAAHGDLATNAAMVLAKDLKMKPRDLAEKIAARLAQVPNVA
KVDVAGPGFINLTLDAGYWPGVLAALLRAGTDFGRSDLGGGEAVNVEYVSANPTGPMHVGHCRGAVFGDALASLLAFAGF
KVTREYYINDAGAQVDVLARSAYLRYREAATGETVEIPDGLYPGDYLVPVGKTLAEVHGSEYLESPESEWLPIFRTFAIG
AMMEMIRDDLQALGISFDVFFSERSLTAAGIDRVGLTIEQLRRTGEVYEGRLPPPKGAPIEDWEDREQSLFRSTAHGDDV
DRPLVKSDGSYTYFAGDIAYHKDKFDRGFRRMIDVWGADHGGYVKRMQAAVKAVTAGQATLDVELCQLVRLLRNGEQVRM
SKRAGSFVTLREVVDEVGRDAVRFMMLFRKNDATLDFDLAKVIEQSRENPVFYVQYAHARAQSILRNAKEQHADLPESGA
IYAHAPLDRLTDEGELGLVKRLAGWPRLVEQAAHAREPHRVAFYLHEVASEFHGQWNRGKDLPHLRFIIENDRELTMARL
ALVHGVAAVLASGLGLLGVEAVDEMK

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=609, Percent_Identity=25.615763546798, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1788184, Length=631, Percent_Identity=25.8320126782884, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71985061, Length=607, Percent_Identity=25.7001647446458, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71985068, Length=569, Percent_Identity=25.6590509666081, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=620, Percent_Identity=25, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321883, Length=619, Percent_Identity=23.5864297253635, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18859963, Length=629, Percent_Identity=24.0063593004769, Blast_Score=100, Evalue=5e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_AZOC5 (A8I9L7)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001525722.1
- ProteinModelPortal:   A8I9L7
- GeneID:   5688776
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_2806
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   ACAU438753:AZC_2806-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64362; Mature: 64362

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVYAIFADHVREAVAALAGELPEAGALDLSRIVVEPPRDAAHGDLATNAAMVLAKDLKM
CCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCCCHHHHHHHHHHHHCCC
KPRDLAEKIAARLAQVPNVAKVDVAGPGFINLTLDAGYWPGVLAALLRAGTDFGRSDLGG
CHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCC
GEAVNVEYVSANPTGPMHVGHCRGAVFGDALASLLAFAGFKVTREYYINDAGAQVDVLAR
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHEECCCCCCHHHHHH
SAYLRYREAATGETVEIPDGLYPGDYLVPVGKTLAEVHGSEYLESPESEWLPIFRTFAIG
HHHHHHHHHCCCCEEECCCCCCCCCEEEHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHH
AMMEMIRDDLQALGISFDVFFSERSLTAAGIDRVGLTIEQLRRTGEVYEGRLPPPKGAPI
HHHHHHHHHHHHHCCEEEEEECCCCCCHHCHHHHCCCHHHHHHCCHHHCCCCCCCCCCCC
EDWEDREQSLFRSTAHGDDVDRPLVKSDGSYTYFAGDIAYHKDKFDRGFRRMIDVWGADH
CCHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
GGYVKRMQAAVKAVTAGQATLDVELCQLVRLLRNGEQVRMSKRAGSFVTLREVVDEVGRD
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHHHH
AVRFMMLFRKNDATLDFDLAKVIEQSRENPVFYVQYAHARAQSILRNAKEQHADLPESGA
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC
IYAHAPLDRLTDEGELGLVKRLAGWPRLVEQAAHAREPHRVAFYLHEVASEFHGQWNRGK
EEEECCHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
DLPHLRFIIENDRELTMARLALVHGVAAVLASGLGLLGVEAVDEMK
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNVYAIFADHVREAVAALAGELPEAGALDLSRIVVEPPRDAAHGDLATNAAMVLAKDLKM
CCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCCCHHHHHHHHHHHHCCC
KPRDLAEKIAARLAQVPNVAKVDVAGPGFINLTLDAGYWPGVLAALLRAGTDFGRSDLGG
CHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCC
GEAVNVEYVSANPTGPMHVGHCRGAVFGDALASLLAFAGFKVTREYYINDAGAQVDVLAR
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHEECCCCCCHHHHHH
SAYLRYREAATGETVEIPDGLYPGDYLVPVGKTLAEVHGSEYLESPESEWLPIFRTFAIG
HHHHHHHHHCCCCEEECCCCCCCCCEEEHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHH
AMMEMIRDDLQALGISFDVFFSERSLTAAGIDRVGLTIEQLRRTGEVYEGRLPPPKGAPI
HHHHHHHHHHHHHCCEEEEEECCCCCCHHCHHHHCCCHHHHHHCCHHHCCCCCCCCCCCC
EDWEDREQSLFRSTAHGDDVDRPLVKSDGSYTYFAGDIAYHKDKFDRGFRRMIDVWGADH
CCHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
GGYVKRMQAAVKAVTAGQATLDVELCQLVRLLRNGEQVRMSKRAGSFVTLREVVDEVGRD
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHHHH
AVRFMMLFRKNDATLDFDLAKVIEQSRENPVFYVQYAHARAQSILRNAKEQHADLPESGA
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC
IYAHAPLDRLTDEGELGLVKRLAGWPRLVEQAAHAREPHRVAFYLHEVASEFHGQWNRGK
EEEECCHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
DLPHLRFIIENDRELTMARLALVHGVAAVLASGLGLLGVEAVDEMK
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA