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The map label for this gene is mcp4 [H]

Identifier: 158424336

GI number: 158424336

Start: 3078747

End: 3080891

Strand: Direct

Name: mcp4 [H]

Synonym: AZC_2712

Alternate gene names: 158424336

Gene position: 3078747-3080891 (Clockwise)

Preceding gene: 158424335

Following gene: 158424337

Centisome position: 57.33

GC content: 66.25

Gene sequence:

>2145_bases
TTGGCACAAGCTTGTCATGCCCAGAATGTCGCAGAATTCCCTGGGGCTTTTGGCATGACCATCACCATCCGGACGGCACT
TGTTTCCCTGTTCTGCGTCATGAGCGCAGTCATCATCGTAATGTGCGGCCTCACGCTCTCCACCGCGAAGCGCAATTACG
ATGGCGCGAAGGAGGCGGCCAGTCTCGCCTCCGTCGAAATGGACATCCTCCAGGCGCTTTCGGTCTTCCGTCTGGAACGC
GGGTCCATGGTCACGCTGCTGACGGTGGAGGGTGCCTACACGCCCGCCCAGCAGGAGCAGATGAACCAGCGCCGTCAGAT
CGCCGCCAAGGCGATGACCGCGGCTGCGCCCAAGATCGACGCTCTGACCCATCAGAAGCTCCTCGCCATCGGCAAGGATC
TCAAGAGCCAGTTCGCCAACATGGACCGGCTTCGGGAAGCCGCCGACCGCGACCTGCCCCGTCCCCTGGCGCAGCGCGAG
GCCGGCCTCTCCAAGCGGATCAATGACGACGGCGGTCGCCTGATGACCACCATGGAGAAGTTCCTGGACACGGCGGAAGA
CGGCATCCGCGCGAACGATCCGACCCTCTCCCAGTTCATCCTCTCCCGCACCATGGCGTGGGACGTGCGCAGCTATGTGG
GCACGATCAACGGCATGCTGAACACCGTCGTCGGCGCAGAGCGCCCGTTCAAGCCGGAGGAAGACCGCACGGTCACCGAC
CTCGACGGCCGCGTGACCGCCGCCTGGAAGCCGGTGCTCGACGTGGCGGACAATGACGACACTTCGCCAGACCTGAAGAA
GTCGATCCAGATCGCGCAGGAGACCTATTTCGGCGGCTCGTTCAAGAAGCTGCGCGACGACATCCTGTCCAACCTTCGCA
ACGGCAAGCCTGCCGGTGTGGCCCTCAACGCTTGGCGCGACGCCAGCCAGACGCAGAACACCTTCTCCGACGTCGCCATG
GTCTCCATAAAGTCGATCGTGGAAGCGGCGAATGCGCGGGAGGCGACCGCCTTCCGCAACCTGCTCACCTACAGCGCCAT
CCTCGTGTTCGCCGTCGCTCTCACGGTGGTCGGCCTTCTGGTGGTGCTGCGGCGCGTCACGGGACCCATCAGCCGCCTGA
CCCATGTCATGACGGACGTCGCCAGCGGCGACCTCGAGGTGGAAATCCCCGGCACCCAGCGGCACGACGAGATCGGCGCC
ATGGCCAAGGCGCTGATGGTGTTCAAGGAGAGCCTCGTGCGCAACCGCGGCATGGAGGCCGAAGCCGCCCGCCAGCGGAC
CGAGGCCGAGCTGGAGCGCAAGCGCATGATGCAGAACCTCGCGGGCGAATTCGAGCGCGAGGTGGGCGGCATCGTCGGGA
CCGTGGCCTCCTCCTCCCAGCAGCTTCAGCAGACCGCCGGCCGCATGGCGAAGGCCGCCGAGAAGACCTCCAGCCAGTCC
ACCGCCGTCGCGGCAGCCGCCGAGGAGGCTTCCACCAACGTGGTCATGGTCGCTTCCTCCGCCGAGGAACTGGGGTCCTC
CGTGGACGAGATCGGCCGCCAGGTGCTGCAGTCGGCGGAAATGTCGAAGGTCGCCGTTGCTGAAGCGGAGAAGACCGGAA
CGGTCATTCAGGATCTCGCCCAGGCGGCCGGCCGCATCGGGGCCGTGGTGGGTCTCATCTCCTCGATTGCCGAGCAGACC
AACCTGCTCGCCCTCAACGCCACCATCGAGGCCGCACGTGCGGGTGATGCCGGCAAGGGCTTCGCGGTGGTCGCGTCCGA
GGTGAAGGCGCTGGCCACGCAGACGGCCAAGGCCACCGAAGAGATCGAGAGCCAGATCGGCGCCATCCAGGCCACCACCC
AACAGGCGGTGACGGTTATCGAGGGCGTCGGACTCCAGATCCGCAAGATGAGCGATGTCGCTGCCAGCATTTCCGCTGCC
GTGGAAGAGCAGGGCGTCGCGACCCGCGAGATCGTGCGTAACGTGGACCAGGCGGCCACCGGCACGAACACCGTCACCTC
CCACATCGCGGACGTCGCCAAGACGGCGGACGAGACGGGAGAGGCGGCGGGACAGGTGCTCCAGGCCTCGACCGCGCTTA
CCGATCAGGCCAAGCGCCTGGAGGCCCAGATGCAGCAGTTCCTCGCCACGGTCCGGGCCAGCTGA

Upstream 100 bases:

>100_bases
CAGGCACTCACTCCAGCCCGCCGAACGGGTATAAACATTTAGATTCAGGTTATAATTCCTGCCGGAAAGGCCTATAGAAG
CCGCGCACCCACCTGAAAGG

Downstream 100 bases:

>100_bases
ACCGCATCCTCGAGGAAGAGTGCAAAGCCCCGACCATCGGTCGGGGCTTTTGTTTTTCAAGCTTGGTCTGCTGAGCGGAC
GCGCCCGAGCGGCGAACCTT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MAQACHAQNVAEFPGAFGMTITIRTALVSLFCVMSAVIIVMCGLTLSTAKRNYDGAKEAASLASVEMDILQALSVFRLER
GSMVTLLTVEGAYTPAQQEQMNQRRQIAAKAMTAAAPKIDALTHQKLLAIGKDLKSQFANMDRLREAADRDLPRPLAQRE
AGLSKRINDDGGRLMTTMEKFLDTAEDGIRANDPTLSQFILSRTMAWDVRSYVGTINGMLNTVVGAERPFKPEEDRTVTD
LDGRVTAAWKPVLDVADNDDTSPDLKKSIQIAQETYFGGSFKKLRDDILSNLRNGKPAGVALNAWRDASQTQNTFSDVAM
VSIKSIVEAANAREATAFRNLLTYSAILVFAVALTVVGLLVVLRRVTGPISRLTHVMTDVASGDLEVEIPGTQRHDEIGA
MAKALMVFKESLVRNRGMEAEAARQRTEAELERKRMMQNLAGEFEREVGGIVGTVASSSQQLQQTAGRMAKAAEKTSSQS
TAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVLQSAEMSKVAVAEAEKTGTVIQDLAQAAGRIGAVVGLISSIAEQT
NLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTQQAVTVIEGVGLQIRKMSDVAASISAA
VEEQGVATREIVRNVDQAATGTNTVTSHIADVAKTADETGEAAGQVLQASTALTDQAKRLEAQMQQFLATVRAS

Sequences:

>Translated_714_residues
MAQACHAQNVAEFPGAFGMTITIRTALVSLFCVMSAVIIVMCGLTLSTAKRNYDGAKEAASLASVEMDILQALSVFRLER
GSMVTLLTVEGAYTPAQQEQMNQRRQIAAKAMTAAAPKIDALTHQKLLAIGKDLKSQFANMDRLREAADRDLPRPLAQRE
AGLSKRINDDGGRLMTTMEKFLDTAEDGIRANDPTLSQFILSRTMAWDVRSYVGTINGMLNTVVGAERPFKPEEDRTVTD
LDGRVTAAWKPVLDVADNDDTSPDLKKSIQIAQETYFGGSFKKLRDDILSNLRNGKPAGVALNAWRDASQTQNTFSDVAM
VSIKSIVEAANAREATAFRNLLTYSAILVFAVALTVVGLLVVLRRVTGPISRLTHVMTDVASGDLEVEIPGTQRHDEIGA
MAKALMVFKESLVRNRGMEAEAARQRTEAELERKRMMQNLAGEFEREVGGIVGTVASSSQQLQQTAGRMAKAAEKTSSQS
TAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVLQSAEMSKVAVAEAEKTGTVIQDLAQAAGRIGAVVGLISSIAEQT
NLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTQQAVTVIEGVGLQIRKMSDVAASISAA
VEEQGVATREIVRNVDQAATGTNTVTSHIADVAKTADETGEAAGQVLQASTALTDQAKRLEAQMQQFLATVRAS
>Mature_713_residues
AQACHAQNVAEFPGAFGMTITIRTALVSLFCVMSAVIIVMCGLTLSTAKRNYDGAKEAASLASVEMDILQALSVFRLERG
SMVTLLTVEGAYTPAQQEQMNQRRQIAAKAMTAAAPKIDALTHQKLLAIGKDLKSQFANMDRLREAADRDLPRPLAQREA
GLSKRINDDGGRLMTTMEKFLDTAEDGIRANDPTLSQFILSRTMAWDVRSYVGTINGMLNTVVGAERPFKPEEDRTVTDL
DGRVTAAWKPVLDVADNDDTSPDLKKSIQIAQETYFGGSFKKLRDDILSNLRNGKPAGVALNAWRDASQTQNTFSDVAMV
SIKSIVEAANAREATAFRNLLTYSAILVFAVALTVVGLLVVLRRVTGPISRLTHVMTDVASGDLEVEIPGTQRHDEIGAM
AKALMVFKESLVRNRGMEAEAARQRTEAELERKRMMQNLAGEFEREVGGIVGTVASSSQQLQQTAGRMAKAAEKTSSQST
AVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVLQSAEMSKVAVAEAEKTGTVIQDLAQAAGRIGAVVGLISSIAEQTN
LLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTQQAVTVIEGVGLQIRKMSDVAASISAAV
EEQGVATREIVRNVDQAATGTNTVTSHIADVAKTADETGEAAGQVLQASTALTDQAKRLEAQMQQFLATVRAS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=360, Percent_Identity=26.1111111111111, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI2367378, Length=341, Percent_Identity=27.8592375366569, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789453, Length=384, Percent_Identity=27.8645833333333, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1788194, Length=185, Percent_Identity=34.0540540540541, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788195, Length=227, Percent_Identity=28.1938325991189, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 75951; Mature: 75820

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQACHAQNVAEFPGAFGMTITIRTALVSLFCVMSAVIIVMCGLTLSTAKRNYDGAKEAA
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHH
SLASVEMDILQALSVFRLERGSMVTLLTVEGAYTPAQQEQMNQRRQIAAKAMTAAAPKID
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
ALTHQKLLAIGKDLKSQFANMDRLREAADRDLPRPLAQREAGLSKRINDDGGRLMTTMEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHCCCCCCHHHHHHHHH
FLDTAEDGIRANDPTLSQFILSRTMAWDVRSYVGTINGMLNTVVGAERPFKPEEDRTVTD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEC
LDGRVTAAWKPVLDVADNDDTSPDLKKSIQIAQETYFGGSFKKLRDDILSNLRNGKPAGV
CCCCEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCE
ALNAWRDASQTQNTFSDVAMVSIKSIVEAANAREATAFRNLLTYSAILVFAVALTVVGLL
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLRRVTGPISRLTHVMTDVASGDLEVEIPGTQRHDEIGAMAKALMVFKESLVRNRGMEA
HHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
EAARQRTEAELERKRMMQNLAGEFEREVGGIVGTVASSSQQLQQTAGRMAKAAEKTSSQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
TAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVLQSAEMSKVAVAEAEKTGTVIQDLA
HHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAGRIGAVVGLISSIAEQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATE
HHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIESQIGAIQATTQQAVTVIEGVGLQIRKMSDVAASISAAVEEQGVATREIVRNVDQAAT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GTNTVTSHIADVAKTADETGEAAGQVLQASTALTDQAKRLEAQMQQFLATVRAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQACHAQNVAEFPGAFGMTITIRTALVSLFCVMSAVIIVMCGLTLSTAKRNYDGAKEAA
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHH
SLASVEMDILQALSVFRLERGSMVTLLTVEGAYTPAQQEQMNQRRQIAAKAMTAAAPKID
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
ALTHQKLLAIGKDLKSQFANMDRLREAADRDLPRPLAQREAGLSKRINDDGGRLMTTMEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHCCCCCCHHHHHHHHH
FLDTAEDGIRANDPTLSQFILSRTMAWDVRSYVGTINGMLNTVVGAERPFKPEEDRTVTD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEC
LDGRVTAAWKPVLDVADNDDTSPDLKKSIQIAQETYFGGSFKKLRDDILSNLRNGKPAGV
CCCCEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCE
ALNAWRDASQTQNTFSDVAMVSIKSIVEAANAREATAFRNLLTYSAILVFAVALTVVGLL
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLRRVTGPISRLTHVMTDVASGDLEVEIPGTQRHDEIGAMAKALMVFKESLVRNRGMEA
HHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
EAARQRTEAELERKRMMQNLAGEFEREVGGIVGTVASSSQQLQQTAGRMAKAAEKTSSQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
TAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVLQSAEMSKVAVAEAEKTGTVIQDLA
HHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAGRIGAVVGLISSIAEQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATE
HHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIESQIGAIQATTQQAVTVIEGVGLQIRKMSDVAASISAAVEEQGVATREIVRNVDQAAT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GTNTVTSHIADVAKTADETGEAAGQVLQASTALTDQAKRLEAQMQQFLATVRAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]